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Neumora Therapeutics, Inc. (NMRA)

Healthcare | Biotechnology | Watertown, United States | NasdaqGS
1.39 USD -0.09 (-6.081%) ⇩ (Aug. 28, 2026, 4 p.m. EDT)
After hours: 1.41 +0.02 (1.432%) ⇧ (Aug. 28, 2026, 7:31 p.m. EDT)

Short-term:★☆☆☆☆Long-term:⯪☆☆☆☆Dividends:☆☆☆☆☆
Hot Take | Aug. 22, 2026, 1:05 a.m. EDT

Neumora Therapeutics is currently a distressed biotech play defined by catastrophic clinical failure and a collapsing business model. The company recently failed late-stage trials for its lead depression drug, triggering a 49% stock plunge, a 35% workforce reduction, and the scrapping of that entire pipeline segment. Fundamentally, the picture is dire: the stock has lost 86% of its value in the last year, the company is burning through cash with negative free cash flow of nearly $100 million, and it carries significant debt relative to its tiny market cap. While the balance sheet shows a current ratio above 4, suggesting some liquidity runway, the operational reality is that the core product portfolio is being dismantled. Analysts remain bullish on paper with a mean target of $6, but this ignores the fundamental destruction of value and the high probability of further dilution or bankruptcy as the company pivots. The options market confirms this pessimism, with traders loading up on puts at the $2.00 level, betting on further decline. There is no reliable path to recovery without a miraculous new asset discovery, making this a high-risk speculative trap rather than an investment opportunity.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoTheta ✓0.070632
MSTL0.130267
AutoARIMA0.138635
AutoETS0.138636

Forecast horizon: 45 days | Selected: AutoTheta

Forecast Reliability
Score 27%
H-stat 0.04
Ljung-Box p 0.198
Jarque-Bera p 7.378546864975363e-205
Excess Kurtosis 20.82
Attribute Value
Sector Healthcare
Debt to Equity Ratio 119.616
Market Cap 261,175,296
Forward P/E -2.08
Beta 2.78
Website https://www.neumoratx.com

As of Aug. 22, 2026, 1:05 a.m. EDT: Speculators are overwhelmingly positioning for downside protection rather than upside participation. Put volume and open interest vastly exceed call volume across all expirations, with massive concentration in the $2.00 strike for September and October. This indicates a strong consensus among traders that the stock will struggle to recover from recent lows, despite some speculative call buying at distant $5.00 strikes.


Info Dump

Attribute Value
52 Week Change -0.2011494
Address1 260 Arsenal Place
Address2 Suite 1
All Time High 21.0
All Time Low 0.611
Ask 10.0
Ask Size 4
Average Analyst Rating 1.8 - Buy
Average Daily Volume10 Day 822,090
Average Daily Volume3 Month 1,894,290
Average Volume 1,894,290
Average Volume10Days 822,090
Beta 2.779
Bid 1.08
Bid Size 2
Book Value 0.238
City Watertown
Compensation As Of Epoch Date 1,767,139,200
Country United States
Crypto Tradeable 0
Currency USD
Current Price 1.39
Current Ratio 4.496
Custom Price Alert Confidence HIGH
Date Short Interest 1,786,665,600
Day High 1.51
Day Low 1.38
Debt To Equity 119.616
Display Name Neumora Therapeutics
Earnings Call Timestamp End 1,774,872,000
Earnings Call Timestamp Start 1,774,872,000
Earnings Timestamp 1,786,710,600
Earnings Timestamp End 1,793,881,800
Earnings Timestamp Start 1,793,881,800
Ebitda -206,187,008
Ebitda Margins 0.0
Enterprise To Ebitda -0.958
Enterprise Value 197,593,312
Eps Current Year -0.87163
Eps Forward -0.66933
Eps Trailing Twelve Months -1.15
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 1.6059
Fifty Day Average Change -0.21590006
Fifty Day Average Change Percent -0.13444178
Fifty Two Week Change Percent -20.11494
Fifty Two Week High 3.65
Fifty Two Week High Change -2.2600002
Fifty Two Week High Change Percent -0.6191781
Fifty Two Week Low 0.83
Fifty Two Week Low Change 0.56
Fifty Two Week Low Change Percent 0.6746988
Fifty Two Week Range 0.83 - 3.65
Financial Currency USD
First Trade Date Milliseconds 1,694,698,200,000
Float Shares 116,363,938
Forward Eps -0.66933
Forward P E -2.0767035
Free Cashflow -99,416,872
Full Exchange Name NasdaqGS
Full Time Employees 63
Fullday Change -0.09
Fullday Change Percent -6.08108
Fullday Price 1.4099
Gmt Off Set Milliseconds -14,400,000
Gross Margins 0.0
Has Pre Post Market Data 1
Held Percent Insiders 0.23251
Held Percent Institutions 0.60113996
Implied Shares Outstanding 187,895,912
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Ipo Expected Date 2,023-09-15
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Neumora Therapeutics, Inc., a clinical-stage biopharmaceutical company, engages in developing therapeutic treatments for brain diseases, neuropsychiatric disorders, and neurodegenerative diseases in the United States. The company develops navacaprant (NMRA-140), a novel once-daily oral kappa opioid receptor antagonist, which is in phase 3 clinical trials for the treatment of major depressive disorder. It also develops NMRA-511 that is in Phase 1b clinical trials in patients with agitation associated with dementia due to Alzheimer's disease; and NMRA-861 and NMRA-898, a M4 muscarinic receptor positive allosteric modulators (PAMs) for schizophrenia and other neuropsychiatric disorders. In addition, the company's preclinical phase product includes NMRA-GCase, an activator program for the treatment of Parkinson's Disease; NMRA-CK1d, a casein kinase 1 isoform delta (CK1d) inhibitor program for Amyotrophic Lateral Sclerosis; and NMRA-215 a brain-penetrant oral NLRP3 inhibitor for the treatment of obesity. The company was formerly known as RBNC Therapeutics, Inc. and changed its name to Neumora Therapeutics, Inc. in October 2021. Neumora Therapeutics, Inc. was incorporated in 2019 and is headquartered in Watertown, Massachusetts.
Long Name Neumora Therapeutics, Inc.
Market us_market
Market Cap 261,175,296
Market State CLOSED
Max Age 86,400
Message Board Id finmb_1684602478
Most Recent Quarter 1,782,777,600
Net Income To Common -212,744,992
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 278,085,949
Number Of Analyst Opinions 7
Open 1.5
Operating Cashflow -180,520,000
Operating Margins 0.0
Payout Ratio 0.0
Phone 857 760 0900
Post Market Change 0.019899964
Post Market Change Percent 1.4316521
Post Market Price 1.4099
Post Market Time 1,787,959,906
Previous Close 1.48
Price Eps Current Year -1.5947133
Price Hint 4
Price To Book 5.840336
Profit Margins 0.0
Quick Ratio 4.206
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key buy
Recommendation Mean 1.77778
Region US
Regular Market Change -0.09
Regular Market Change Percent -6.08108
Regular Market Day High 1.51
Regular Market Day Low 1.38
Regular Market Day Range 1.38 - 1.51
Regular Market Open 1.5
Regular Market Previous Close 1.48
Regular Market Price 1.39
Regular Market Time 1,787,947,200
Regular Market Volume 694,554
Return On Assets -0.7385
Return On Equity -1.87112
Sand P52 Week Change 0.20204377
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 187,895,912
Shares Percent Shares Out 0.0425
Shares Short 7,991,116
Shares Short Previous Month Date 1,784,073,600
Shares Short Prior Month 7,786,397
Short Name Neumora Therapeutics, Inc.
Short Percent Of Float 0.0727
Short Ratio 12.24
Source Interval 15
State MA
Symbol NMRA
Target High Price 14.0
Target Low Price 3.0
Target Mean Price 6.14286
Target Median Price 5.0
Total Cash 116,834,000
Total Cash Per Share 0.622
Total Debt 53,252,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -1.15
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 2.09775
Two Hundred Day Average Change -0.70774996
Two Hundred Day Average Change Percent -0.3373853
Type Disp Equity
Volume 694,554
Website https://www.neumoratx.com
Zip 2,472