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Nektar Therapeutics (NKTR)

Healthcare | Biotechnology | San Francisco, United States | NasdaqCM
84.86 USD +0.87 (1.036%) ⇧ (April 17, 2026, 4 p.m. EDT)

Short-term: ★★☆☆☆ | Long-term: ☆☆☆☆☆ | Dividends: ★★☆☆☆
Hot Take | April 19, 2026, 12:53 a.m. EDT

The stock is trading as a 'make-or-break' binary playsight on their REZPEG data, supported by aggressive call positioning at 100-110 strikes. However, the deteriorating fundamentals (-25% revenue growth, negative earnings, high debt/equity) and the presence of active litigation class action deadlinewith 26 suggest a high risk of value destruction. The bullish IV spikes at deep OTM levels are a contrarian signal that speculators fear a catalyst failure as much as they hope for a moonshot success.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
MSTL ✓0.517813
AutoETS0.521947
AutoTheta0.657326
AutoARIMA0.790572

Forecast horizon: 45 days | Selected: MSTL

Forecast Reliability
Score 31%
H-stat 5.08
Ljung-Box p 0.000
Jarque-Bera p 0.008
Excess Kurtosis -0.68
Attribute Value
Sector Healthcare
Debt to Equity Ratio 165.763
Revenue per Share 3.274
Market Cap 2,434,460,672
Forward P/E -7.55
Beta 1.18
Profit Margins -297.07%
Website https://www.nektar.com

As of April 19, 2026, 12:53 a.m. EDT: Options flow is dominated by long calls at high strikes (100-110) by August/Nov 2026, while short-to-mid-term expiries show heavy put options (OTM) on declines, likely hedging a specific catalyst or earnings date. However, the IV profile is notably distorted with spikes at deeply OTM strikes (e.g., 43-strike puts), suggesting intelligence-betting on extreme downside fear or a binary event like a litigation verdict or drug rejection. The 1.9x average volume relative to OI on 100-strike calls indicates active speculation on upside momentum driven by recent positive trial data.


Info Dump

Attribute Value
52 Week Change 7.9798946
Address1 455 Mission Bay Boulevard South
All Time High 1,670.4
All Time Low 6.15
Ask 96.78
Ask Size 1
Audit Risk 8
Average Analyst Rating 1.3 - Strong Buy
Average Daily Volume10 Day 570,950
Average Daily Volume3 Month 1,099,013
Average Volume 1,099,013
Average Volume10Days 570,950
Beta 1.176
Bid 72.24
Bid Size 1
Board Risk 6
Book Value 4.408
City San Francisco
Compensation As Of Epoch Date 1,735,603,200
Compensation Risk 8
Country United States
Crypto Tradeable 0
Currency USD
Current Price 84.86
Current Ratio 4.974
Custom Price Alert Confidence HIGH
Date Short Interest 1,774,915,200
Day High 86.95
Day Low 84.15
Debt To Equity 165.763
Earnings Call Timestamp End 1,773,349,200
Earnings Call Timestamp Start 1,773,349,200
Earnings Timestamp 1,773,345,600
Earnings Timestamp End 1,778,184,000
Earnings Timestamp Start 1,778,184,000
Ebitda -129,745,000
Ebitda Margins -2.3490899
Enterprise To Ebitda -18.017
Enterprise To Revenue 42.324
Enterprise Value 2,337,616,640
Eps Current Year -10.0125
Eps Forward -11.2375
Eps Trailing Twelve Months -9.73
Esg Populated 0
Exchange NCM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fax 415 339 5300
Fifty Day Average 70.7208
Fifty Day Average Change 14.139198
Fifty Day Average Change Percent 0.19992983
Fifty Two Week Change Percent 797.98944
Fifty Two Week High 86.95
Fifty Two Week High Change -2.0899963
Fifty Two Week High Change Percent -0.024036761
Fifty Two Week Low 7.99
Fifty Two Week Low Change 76.87
Fifty Two Week Low Change Percent 9.620776
Fifty Two Week Range 7.99 - 86.95
Financial Currency USD
First Trade Date Milliseconds 767,971,800,000
Float Shares 24,990,371
Forward Eps -11.2375
Forward P E -7.5515018
Free Cashflow -108,228,872
Full Exchange Name NasdaqCM
Full Time Employees 63
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,775,001,600
Gross Margins 1.0
Gross Profits 55,232,000
Has Pre Post Market Data 1
Held Percent Insiders 0.00575
Held Percent Institutions 0.61064
Implied Shares Outstanding 28,687,963
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Ir Website http://ir.nektar.com/
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Last Split Date 1,749,427,200
Last Split Factor 1:15
Long Business Summary Nektar Therapeutics, a biopharmaceutical company, focuses on discovering and developing medicines in the field of immunotherapy in the United States and internationally. It develops rezpegaldesleukin, which is in Phase 2b to treat underlying immune system imbalance in people with autoimmune disorders and inflammatory diseases; NKTR-0165 to treat ulcerative colitis, vitiligo, and multiple sclerosis; NKTR-0166 to treat autoimmune disease; NKTR-422 to treat fibrotic diseases; and NKTR-255 to treat solid tumors and large b-cell lymphoma. It has collaboration agreements with Takeda Pharmaceutical Company Ltd.; AstraZeneca AB; UCB Pharma; F. Hoffmann-La Roche Ltd; Bausch Health Companies Inc.; Pfizer Inc.; UCB Pharma (Biogen); Bristol-Myers Squibb Company; and Merck KGaA. The company was incorporated in 1990 and is headquartered in San Francisco, California.
Long Name Nektar Therapeutics
Market us_market
Market Cap 2,434,460,672
Market State PRE
Max Age 86,400
Message Board Id finmb_29929
Most Recent Quarter 1,767,139,200
Net Income To Common -164,076,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 2,434,460,540
Number Of Analyst Opinions 8
Open 85.39
Operating Cashflow -208,511,008
Operating Margins -0.87541
Overall Risk 5
Payout Ratio 0.0
Peg Ratio 0.31
Phone 415 482 5300
Previous Close 83.99
Price Eps Current Year -8.475406
Price Hint 2
Price To Book 19.251362
Price To Sales Trailing12 Months 44.076996
Profit Margins -2.9706697
Quick Ratio 4.624
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.3
Region US
Regular Market Change 0.870003
Regular Market Change Percent 1.03584
Regular Market Day High 86.95
Regular Market Day Low 84.15
Regular Market Day Range 84.15 - 86.95
Regular Market Open 85.39
Regular Market Previous Close 83.99
Regular Market Price 84.86
Regular Market Time 1,776,456,000
Regular Market Volume 509,820
Return On Assets -0.27978
Return On Equity -2.17941
Revenue Growth -0.253
Revenue Per Share 3.274
Sand P52 Week Change 0.38150132
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 2
Shares Outstanding 28,687,963
Shares Percent Shares Out 0.1277
Shares Short 3,663,438
Shares Short Previous Month Date 1,772,150,400
Shares Short Prior Month 3,342,020
Short Name Nektar Therapeutics
Short Percent Of Float 0.1293
Short Ratio 4.32
Source Interval 15
State CA
Symbol NKTR
Target High Price 165.0
Target Low Price 70.0
Target Mean Price 128.125
Target Median Price 131.5
Total Cash 245,752,000
Total Cash Per Share 8.566
Total Debt 148,908,000
Total Revenue 55,232,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -9.73
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 50.4832
Two Hundred Day Average Change 34.3768
Two Hundred Day Average Change Percent 0.68095523
Type Disp Equity
Volume 509,820
Website https://www.nektar.com
Zip 94,158