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Neurogene Inc. (NGNE)

Healthcare | Biotechnology | New York, United States | NasdaqGM
21.56 USD -2.88 (-11.784%) ⇩ (Oct. 13, 2026, 4 p.m. EDT)
After hours: 21.95 +0.39 (1.809%) ⇧ (Oct. 13, 2026, 6:20 p.m. EDT)

Short-term:★⯪☆☆☆Long-term:★☆☆☆☆Dividends:☆☆☆☆☆
Hot Take ↕ | Oct. 10, 2026, 1:52 a.m. EDT

Neurogene presents a classic biotech value trap where the business fundamentals and market pricing tell a story of severe distress, despite the allure of a potential blockbuster drug. The company is burning cash aggressively, with operating and free cash flows deeply negative, while returning losses to shareholders via dilution. The balance sheet, though currently showing low debt, is propped up by significant cash reserves that are being consumed rapidly by R&D and operational costs. The stock has suffered a catastrophic multi-year decline, dropping nearly 89% over the last nine years, with the most recent annual performance also negative. This long-term erosion suggests the market has already priced in the failure of the pipeline or the inability to generate sustainable revenue. The short-term outlook remains bleak due to this structural weakness. Although the price has recently dipped below its 200-day moving average, offering a slight technical bounce opportunity, the lack of positive momentum and the heavy selling pressure make a strong reversal unlikely without a major catalyst. The statistical forecasting models offer no help here, showing a weak, unreliable signal that cannot overcome the fundamental reality of the company's financial bleed. Crucially, there is no dividend to provide any income cushion or signal of financial stability; the company is entirely focused on survival and growth, not shareholder returns. The options market confirms this pessimism, with traders stacking up cheap insurance (puts) for the distant future rather than betting on a recovery. Investors should view this as a high-risk speculative vehicle suitable only for those willing to accept the possibility of total capital loss in exchange for a lottery ticket on a clinical trial success, rather than a sound investment.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoETS ✓0.088234
MSTL0.088824
AutoARIMA0.092356
AutoTheta0.093201

Forecast horizon: 45 days | Selected: AutoETS

Forecast Reliability
Score 40%
H-stat 2.47
Ljung-Box p 0.000
Jarque-Bera p 0.050
Excess Kurtosis 0.23
Attribute Value
Sector Healthcare
Debt to Equity Ratio 3.843
Market Cap 431,445,376
Forward P/E -3.79
Beta 2.09
Website https://www.neurogene.com

As of Oct. 10, 2026, 1:52 a.m. EDT: Speculators are heavily positioning for downside protection, evidenced by massive open interest in deep out-of-the-money puts expiring late in 2027 compared to negligible call volume. While there is some call activity at strikes significantly above the current price, the overwhelming capital deployment is in put writing and buying at lower strikes, suggesting a fear of a prolonged decline rather than an expectation of a near-term rally.


Info Dump

Attribute Value
52 Week Change -0.28891474
Address1 535 W 24th Street
Address2 5th Floor
All Time High 1,115.0
All Time Low 6.875
Ask 44.63
Ask Size 2
Audit Risk 9
Average Analyst Rating 1.1 - Strong Buy
Average Daily Volume10 Day 273,060
Average Daily Volume3 Month 252,334
Average Volume 252,334
Average Volume10Days 273,060
Beta 2.088
Bid 25.99
Bid Size 2
Board Risk 7
Book Value 13.716
City New York
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 9
Country United States
Crypto Tradeable 0
Currency USD
Current Price 21.56
Current Ratio 10.645
Custom Price Alert Confidence HIGH
Date Short Interest 1,790,726,400
Day High 25.1744
Day Low 21.395
Debt To Equity 3.843
Display Name Neurogene
Dividend Yield 0.0
Earnings Timestamp 1,786,451,400
Earnings Timestamp End 1,794,486,600
Earnings Timestamp Start 1,794,486,600
Ebitda -117,990,000
Ebitda Margins 0.0
Enterprise To Ebitda -1.817
Enterprise Value 214,398,400
Eps Current Year -5.74514
Eps Forward -5.68544
Eps Trailing Twelve Months -5.04
Esg Populated 0
Exchange NGM
Exchange Data Delayed By 15
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 33.8084
Fifty Day Average Change -12.2484
Fifty Day Average Change Percent -0.36228865
Fifty Two Week Change Percent -28.891474
Fifty Two Week High 43.66
Fifty Two Week High Change -22.1
Fifty Two Week High Change Percent -0.50618416
Fifty Two Week Low 15.93
Fifty Two Week Low Change 5.629999
Fifty Two Week Low Change Percent 0.35342115
Fifty Two Week Range 15.93 - 43.66
Financial Currency USD
First Trade Date Milliseconds 1,394,202,600,000
Float Shares 11,300,027
Forward Eps -5.68544
Forward P E -3.7921426
Free Cashflow -48,083,752
Full Exchange Name NasdaqGM
Full Time Employees 131
Fullday Change -2.4899998
Fullday Change Percent -10.188214
Fullday Price 21.56
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,790,812,800
Gross Margins 0.0
Gross Profits -88,378,000
Has Pre Post Market Data 1
Held Percent Insiders 0.0698
Held Percent Institutions 0.976
Implied Shares Outstanding 20,011,382
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Last Split Date 1,702,944,000
Last Split Factor 1:4
Long Business Summary Neurogene Inc., a clinical stage biotechnology company, develops genetic medicines for rare neurological diseases. The company's product candidates include NGN-401 that is packaged in an adeno-associated virus 9, which is in Phase 1/2 clinical trial for the treatment of Rett syndrome; and NGN-101, a conventional gene therapy candidate that is in Phase 1/2 clinical trial to treat CLN5 Batten disease. It has a license agreement with The University of Edinburgh, Virovek, Inc., Sigma-Aldrich Co. LLC., and Leland Stanford Junior University. The company was founded in 2018 and is headquartered in New York, New York.
Long Name Neurogene Inc.
Market us_market
Market Cap 431,445,376
Market State PREPRE
Max Age 86,400
Message Board Id finmb_602062523
Most Recent Quarter 1,782,777,600
Net Income To Common -111,110,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 618,952,045
Number Of Analyst Opinions 8
Open 24.32
Operating Cashflow -86,817,000
Operating Margins 0.0
Overall Risk 8
Phone 855 508 3568
Post Market Change 0.3900013
Post Market Change Percent 1.8089114
Post Market Price 21.95
Post Market Time 1,791,930,000
Previous Close 24.44
Price Eps Current Year -3.752737
Price Hint 2
Price To Book 1.5718869
Profit Margins 0.0
Quick Ratio 10.501
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.1
Region US
Regular Market Change -2.88
Regular Market Change Percent -11.784
Regular Market Day High 25.1744
Regular Market Day Low 21.395
Regular Market Day Range 21.395 - 25.1744
Regular Market Open 24.32
Regular Market Previous Close 24.44
Regular Market Price 21.56
Regular Market Time 1,791,921,600
Regular Market Volume 441,219
Return On Assets -0.27975
Return On Equity -0.45314997
Sand P52 Week Change 0.17502642
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 8
Shares Outstanding 20,011,382
Shares Percent Shares Out 0.2486
Shares Short 4,974,749
Shares Short Previous Month Date 1,788,134,400
Shares Short Prior Month 3,135,369
Short Name Neurogene Inc.
Short Percent Of Float 0.295
Short Ratio 16.1
Source Interval 15
State NY
Symbol NGNE
Target High Price 166.0
Target Low Price 46.0
Target Mean Price 77.875
Target Median Price 65.0
Total Cash 225,392,000
Total Cash Per Share 11.263
Total Debt 8,345,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -5.04
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 27.40195
Two Hundred Day Average Change -5.8419514
Two Hundred Day Average Change Percent -0.21319473
Type Disp Equity
Volume 441,219
Website https://www.neurogene.com
Zip 10,011