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Neurogene Inc. (NGNE)

Healthcare | Biotechnology | New York, United States | NasdaqGM
38.32 USD -1.31 (-3.306%) ⇩ (July 13, 2026, 4 p.m. EDT)
After hours: 37.56 -0.76 (-0.760%) ⇩ (July 13, 2026, 7:02 p.m. EDT)

Short-term:★★★⯪☆Long-term:★⯪☆☆☆Dividends:☆☆☆☆☆
Hot Take | July 11, 2026, 6:53 a.m. EDT

Neurogene presents a classic 'binary biotech' dilemma where the business thesis is compelling but the financial reality is precarious. The company has secured significant capital ($125M-$134M) to extend its runway into 2029, which is a crucial lifeline for a firm burning cash and reporting negative free cash flow. However, the balance sheet remains fragile with negative equity and a massive short interest (28%), signaling deep skepticism among traditional investors. The short-term outlook is cautiously optimistic due to the upcoming Phase 1/2 data readout for NGN-401. The options market is screaming for a catalyst, with heavy call buying at the $45 strike for late July, implying a belief that the data could trigger a massive re-rating similar to past rallies. Yet, the statistical forecast model is useless here, showing very low confidence, which aligns with the high volatility and lack of earnings visibility. Long-term, the investment case hinges entirely on the success of the Rett syndrome therapy. The stock has suffered a brutal multi-year decline (-85% over 9 years), reflecting the market's fear of failure in this high-risk sector. While the analyst consensus is a 'strong buy' with a target nearly doubling the current price, this is based on potential upside from a successful trial, not current profitability. For now, this is a speculative play on a specific clinical milestone, not a stable income or growth vehicle.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
MSTL_48 ✓0.271428
MSTL0.331573
AutoARIMA0.344044
AutoETS0.350097
AutoTheta0.359314
MSTL_48_900.398121
MSTL_900.449691

Forecast horizon: 60 days | Selected: MSTL_48

Forecast Reliability
Score 24%
H-stat 4.00
Ljung-Box p 0.000
Jarque-Bera p 0.008
Excess Kurtosis 0.98
Attribute Value
Sector Healthcare
Debt to Equity Ratio 3.84
Market Cap 764,496,000
Forward P/E -7.02
Beta 1.96
Website https://www.neurogene.com

As of July 11, 2026, 6:53 a.m. EDT: Speculators are positioning for a binary event rather than a steady trend. Call volume is heavily skewed toward out-of-the-money strikes (45 strike) expiring in late July, suggesting a bet on a sharp spike driven by clinical data or regulatory news. Conversely, put volume is concentrated deep in-the-money (12.5 and 17.5 strikes) for January 2027, indicating a hedge against a prolonged failure or dilution scenario. The massive implied volatility spike on the far-dated deep puts versus zero IV on near-term deep calls confirms the market views the immediate future as volatile but potentially explosive, while the distant future carries a severe downside tail risk.


Info Dump

Attribute Value
52 Week Change 0.7803235
Address1 535 W 24th Street
Address2 5th Floor
All Time High 1,115.0
All Time Low 6.875
Ask 48.37
Ask Size 2
Audit Risk 9
Average Analyst Rating 1.0 - Strong Buy
Average Daily Volume10 Day 445,510
Average Daily Volume3 Month 210,888
Average Volume 210,888
Average Volume10Days 445,510
Beta 1.959
Bid 27.95
Bid Size 2
Board Risk 7
Book Value 15.227
City New York
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 9
Country United States
Crypto Tradeable 0
Currency USD
Current Price 38.32
Current Ratio 13.079
Custom Price Alert Confidence HIGH
Date Short Interest 1,782,777,600
Day High 39.03
Day Low 37.26
Debt To Equity 3.84
Display Name Neurogene
Earnings Timestamp 1,778,616,000
Earnings Timestamp End 1,786,478,400
Earnings Timestamp Start 1,786,478,400
Ebitda -107,454,000
Ebitda Margins 0.0
Enterprise To Ebitda -3.457
Enterprise Value 371,476,832
Eps Current Year -5.31333
Eps Forward -5.4575
Eps Trailing Twelve Months -4.55
Esg Populated 0
Exchange NGM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 30.2318
Fifty Day Average Change 8.0882
Fifty Day Average Change Percent 0.26753947
Fifty Two Week Change Percent 78.03235
Fifty Two Week High 43.66
Fifty Two Week High Change -5.34
Fifty Two Week High Change Percent -0.12230875
Fifty Two Week Low 15.93
Fifty Two Week Low Change 22.39
Fifty Two Week Low Change Percent 1.4055241
Fifty Two Week Range 15.93 - 43.66
Financial Currency USD
First Trade Date Milliseconds 1,394,202,600,000
Float Shares 8,829,470
Forward Eps -5.4575
Forward P E -7.02153
Free Cashflow -47,845,624
Full Exchange Name NasdaqGM
Full Time Employees 131
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,782,864,000
Gross Margins 0.0
Gross Profits -82,281,000
Has Pre Post Market Data 1
Held Percent Insiders 0.07072
Held Percent Institutions 0.88491
Implied Shares Outstanding 19,950,314
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Last Split Date 1,702,944,000
Last Split Factor 1:4
Long Business Summary Neurogene Inc., a clinical stage biotechnology company, develops genetic medicines for rare neurological diseases. The company's product candidates include NGN-401 that is packaged in an adeno-associated virus 9, which is in Phase 1/2 clinical trial for the treatment of Rett syndrome; and NGN-101, a conventional gene therapy candidate that is in Phase 1/2 clinical trial to treat CLN5 Batten disease. It has a license agreement with The University of Edinburgh, Virovek, Inc., Sigma-Aldrich Co. LLC., and Leland Stanford Junior University. The company was founded in 2018 and is headquartered in New York, New York.
Long Name Neurogene Inc.
Market us_market
Market Cap 764,496,000
Market State PREPRE
Max Age 86,400
Message Board Id finmb_602062523
Most Recent Quarter 1,774,915,200
Net Income To Common -98,638,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 788,835,415
Number Of Analyst Opinions 7
Open 38.76
Operating Cashflow -82,518,000
Operating Margins 0.0
Overall Risk 9
Payout Ratio 0.0
Phone 855 508 3568
Post Market Change -0.7599983
Post Market Change Percent -1.9832941
Post Market Price 37.56
Post Market Time 1,783,983,768
Previous Close 39.63
Price Eps Current Year -7.2120495
Price Hint 2
Price To Book 2.5165823
Profit Margins 0.0
Quick Ratio 12.903
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.0
Region US
Regular Market Change -1.31
Regular Market Change Percent -3.30558
Regular Market Day High 39.03
Regular Market Day Low 37.26
Regular Market Day Range 37.26 - 39.03
Regular Market Open 38.76
Regular Market Previous Close 39.63
Regular Market Price 38.32
Regular Market Time 1,783,972,800
Regular Market Volume 235,775
Return On Assets -0.23909001
Return On Equity -0.37252
Sand P52 Week Change 0.20847368
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 8
Shares Outstanding 19,950,314
Shares Percent Shares Out 0.21180001
Shares Short 3,352,320
Shares Short Previous Month Date 1,780,012,800
Shares Short Prior Month 3,545,963
Short Name Neurogene Inc.
Short Percent Of Float 0.2644
Short Ratio 16.62
Source Interval 15
State NY
Symbol NGNE
Target High Price 180.0
Target Low Price 46.0
Target Mean Price 81.71429
Target Median Price 69.0
Total Cash 243,182,000
Total Cash Per Share 15.389
Total Debt 9,130,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -4.55
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 24.22615
Two Hundred Day Average Change 14.093849
Two Hundred Day Average Change Percent 0.58176184
Type Disp Equity
Volume 235,775
Website https://www.neurogene.com
Zip 10,011