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NuCana plc (NCNA)

Healthcare | Biotechnology | Edinburgh, United Kingdom | NasdaqCM
2.27 USD +0.14 (6.573%) ⇧ (April 17, 2026, 12:42 p.m. EDT)

Short-term: ★☆☆☆☆ | Long-term: ☆☆☆☆☆ | Dividends: ☆☆☆☆☆
Hot Take | April 11, 2026, 3:48 p.m. EDT

NCNA is a highly volatile stock with a significant drop in price over the past few months, as evidenced by its 52-week low of $1.33 and current price of $1.97. The stock has shown some recent upward movement, but the overall trend is bearish. The company's financials are weak, with negative earnings and a high debt-to-equity ratio, which indicates financial instability. The lack of dividends and the high short interest suggest that the stock is not a safe investment for either short-term or long-term traders. The recent news of a potential delisting threat further exacerbates the risk. Overall, this stock is not recommended for investment.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoTheta ✓0.418771
MSTL0.439101
AutoARIMA0.445490
AutoETS0.446898

Forecast horizon: 45 days | Selected: AutoTheta

Forecast Reliability
Score 48%
H-stat 4.92
Ljung-Box p 0.000
Jarque-Bera p 0.797
Excess Kurtosis 0.00
Attribute Value
Sector Healthcare
Debt to Equity Ratio 2.779
Market Cap 9,447,674
Trailing P/E Infinity
Forward P/E -0.24
Beta 1.80
Website https://www.nucana.com

Info Dump

Attribute Value
52 Week Change -0.986519
Address1 3 Lochside Way
All Time High 160,000.0
All Time Low 1.33
Ask 2.81
Ask Size 2
Average Daily Volume10 Day 47,660
Average Daily Volume3 Month 50,942
Average Volume 50,942
Average Volume10Days 47,660
Beta 1.799
Bid 1.65
Bid Size 2
Book Value 7.934237
City Edinburgh
Compensation As Of Epoch Date 1,767,139,200
Country United Kingdom
Crypto Tradeable 0
Currency USD
Current Price 2.27
Current Ratio 5.604
Custom Price Alert Confidence HIGH
Date Short Interest 1,774,915,200
Day High 2.33
Day Low 2.16
Debt To Equity 2.779
Display Name NuCana
Earnings Timestamp End 1,755,518,400
Earnings Timestamp Start 1,755,082,740
Ebitda -20,604,000
Ebitda Margins 0.0
Enterprise To Ebitda -2,150.085
Enterprise Value 44,300,349,440
Eps Forward -9.43
Eps Trailing Twelve Months 0.0
Esg Populated 0
Exchange NCM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 1.9545
Fifty Day Average Change 0.31550002
Fifty Day Average Change Percent 0.16142237
Fifty Two Week Change Percent -98.6519
Fifty Two Week High 250.0
Fifty Two Week High Change -247.73
Fifty Two Week High Change Percent -0.99092
Fifty Two Week Low 1.33
Fifty Two Week Low Change 0.93999994
Fifty Two Week Low Change Percent 0.70676684
Fifty Two Week Range 1.33 - 250.0
Financial Currency GBP
First Trade Date Milliseconds 1,506,605,400,000
Float Shares 20,807,898,345
Forward Eps -9.43
Forward P E -0.24072109
Free Cashflow -3,824,625
Full Exchange Name NasdaqCM
Full Time Employees 10
Gmt Off Set Milliseconds -14,400,000
Gross Margins 0.0
Has Pre Post Market Data 1
Held Percent Insiders 0.000020000001
Held Percent Institutions 0.04079
Implied Shares Outstanding 4,161,971
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Last Split Date 1,754,870,400
Last Split Factor 1:200
Long Business Summary NuCana plc, a clinical-stage biopharmaceutical company, engages in the development of medicines to treat patients with cancer in the United States. It applies its ProTide technology to transform prescribed chemotherapy agents and nucleoside analogs into medicines. The company is developing medicines to overcome the limitations of nucleoside analogs and generate concentrations of anti-cancer metabolites in cancer cells. Its pipeline includes NUC-3373, a chemical entity derived from the nucleoside analog 5-fluorouracil that is in Phase 1b/2 study in patients with metastatic colorectal cancer; Phase 2 clinical trial for the second-line treatment of patients with advanced colorectal cancer; and Phase 1b/2 modular clinical trial for patients with advanced solid tumors and lung cancer. It also developing NUC-7738, a ProTide transformation of 3'-deoxyadenosine, which is in the Phase 2 part of a Phase 1/2 clinical trial for patients with advanced solid tumors. It has an assignment, license, and collaboration agreement with Cardiff ProTides Ltd to discover, drug design, and in vitro screen purine and pyrimidine-based nucleosides as potential drug candidates. The company was formerly known as NuCana BioMed Limited and changed its name to NuCana plc in August 2017. NuCana plc was incorporated in 1997 and is based in Edinburgh, the United Kingdom.
Long Name NuCana plc
Market us_market
Market Cap 9,447,674
Market State REGULAR
Max Age 86,400
Message Board Id finmb_50918463
Most Recent Quarter 1,767,139,200
Net Income To Common -29,353,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 8,864,998
Open 2.27
Operating Cashflow -7,467,000
Operating Margins 0.0
Payout Ratio 0.0
Phone 44 13 1357 1111
Previous Close 2.13
Price Hint 4
Price To Book 0.28610185
Profit Margins 0.0
Quick Ratio 5.436
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key none
Region US
Regular Market Change 0.13999987
Regular Market Change Percent 6.5727634
Regular Market Day High 2.33
Regular Market Day Low 2.16
Regular Market Day Range 2.16 - 2.33
Regular Market Open 2.27
Regular Market Previous Close 2.13
Regular Market Price 2.27
Regular Market Time 1,776,444,125
Regular Market Volume 23,191
Return On Assets -0.58322
Return On Equity -1.93871
Sand P52 Week Change 0.36506534
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 4,161,971
Shares Percent Shares Out 0.0405
Shares Short 168,450
Shares Short Previous Month Date 1,772,150,400
Shares Short Prior Month 176,475
Short Name NuCana plc
Short Percent Of Float 0.0405
Short Ratio 3.27
Source Interval 15
Symbol NCNA
Total Cash 24,251,000
Total Cash Per Share 0.001
Total Debt 676,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps 0.0
Trailing P E Infinity
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 4.217825
Two Hundred Day Average Change -1.947825
Two Hundred Day Average Change Percent -0.4618079
Type Disp Equity
Volume 23,191
Website https://www.nucana.com
Zip EH12 9DT