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Mereo BioPharma Group plc (MREO)

Healthcare | Biotechnology | London, United Kingdom | NasdaqCM
0.34 USD +0.01 (3.157%) ⇧ (April 17, 2026, 4 p.m. EDT)
After hours: 0.33 -0.01 (-0.006%) ⇩ (April 17, 2026, 7:56 p.m. EDT)

Short-term: ★★☆☆☆ | Long-term: ☆☆☆☆☆ | Dividends: ☆☆☆☆☆
Hot Take | April 18, 2026, 6:10 p.m. EDT

Mereo BioPharma is a classic value trap masquerading as a turnaround candidate; the combination of failed Phase 3/4 trials, massive burn rates, and a forecasting model predicting a 25% drop over the next 45 days makes any investment here strictly akin to gambling on a rescue that the balance sheet (low cash, high relative burn) cannot afford to support without massive dilution. The options market confirms the doom: while retail chases distant moonshots, smart money is buying insurance on further collapses to the $0.20 level, rendering the stock a definitive 'avoid' for both growth and income strategies.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoTheta ✓0.289214
AutoARIMA0.375660
AutoETS0.398728
MSTL0.553553

Forecast horizon: 45 days | Selected: AutoTheta

Forecast Reliability
Score 41%
H-stat 38.88
Ljung-Box p 0.000
Jarque-Bera p 0.159
Excess Kurtosis -1.39
Attribute Value
Sector Healthcare
Debt to Equity Ratio 0.494
Revenue per Share 0.003
Market Cap 53,726,664
Forward P/E -8.34
Beta 0.38
Website https://www.mereobiopharma.com

As of April 18, 2026, 6:10 p.m. EDT: Speculators are heavily weighted toward downside protection in the near-to-medium term, with significant Open Interest in ITM puts expiring May and August 2026, indicating active hedging or speculative short positions against the current sub-$0.35 price. Conversely, call activity is dominated by extreme OTM strikes (e.g., $1.50, $2.00) with low volume, suggesting long-term 'lottery ticket' speculation rather than genuine bullish conviction for the immediate future. The absence of significant ITM calls and the high put OI at $2.00 and $2.50 strikes highlight a consensus that a recovery to analyst targets is highly improbable without a catastrophic fundamental shift.


Info Dump

Attribute Value
52 Week Change -0.8553648
Address1 One Cavendish Place
Address2 4th Floor
All Time High 8.48
All Time Low 0.2
Ask 0.4264
Ask Size 2
Average Daily Volume10 Day 1,830,160
Average Daily Volume3 Month 3,028,790
Average Volume 3,028,790
Average Volume10Days 1,830,160
Beta 0.376
Bid 0.2366
Bid Size 2
Book Value 0.257
City London
Compensation As Of Epoch Date 1,767,139,200
Country United Kingdom
Crypto Tradeable 0
Currency USD
Current Price 0.3366
Current Ratio 10.465
Custom Price Alert Confidence HIGH
Date Short Interest 1,774,915,200
Day High 0.34
Day Low 0.32
Debt To Equity 0.494
Display Name Mereo BioPharma
Earnings Timestamp 1,773,923,400
Earnings Timestamp End 1,778,589,000
Earnings Timestamp Start 1,778,589,000
Ebitda -37,935,000
Ebitda Margins 0.0
Enterprise To Ebitda -6.006
Enterprise To Revenue 455.687
Enterprise Value 227,843,328
Eps Current Year -0.028
Eps Forward -0.040377297
Eps Trailing Twelve Months -0.25
Esg Populated 0
Exchange NCM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 0.36908
Fifty Day Average Change -0.03248
Fifty Day Average Change Percent -0.0880026
Fifty Two Week Change Percent -85.53648
Fifty Two Week High 3.05
Fifty Two Week High Change -2.7134
Fifty Two Week High Change Percent -0.8896393
Fifty Two Week Low 0.2
Fifty Two Week Low Change 0.1366
Fifty Two Week Low Change Percent 0.683
Fifty Two Week Range 0.2 - 3.05
Financial Currency USD
First Trade Date Milliseconds 1,556,112,600,000
Float Shares 572,326,271
Forward Eps -0.040377297
Forward P E -8.336368
Free Cashflow -18,103,500
Full Exchange Name NasdaqCM
Full Time Employees 39
Gmt Off Set Milliseconds -14,400,000
Gross Margins 0.734
Gross Profits 367,000
Has Pre Post Market Data 1
Held Percent Insiders 0.00959
Held Percent Institutions 0.43346
Implied Shares Outstanding 159,615,766
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Mereo BioPharma Group plc, a biopharmaceutical company, develops and commercializes therapeutics for the treatment of rare diseases in the United Kingdom and the United States. The company develops Setrusumab, an antibody for the treatment of osteogenesis imperfecta; Alvelestat, an oral small molecule that is in Phase II clinical trial to treat Alpha-1 anti-trypsin deficiency associated lung disease; and Vantictumab, an anti-FZD monoclonal antibody for the treatment of autosomal dominant osteopetrosis type 2. It also develops Leflutrozole, an oral aromatase inhibitor, which is in Phase 2 trials for use in the treatment of hypogonadotropic hypogonadism; Navicixizumab, which has completed Phase 1b clinical trials for the treatment of the late line ovarian cancer; Etigilimab, an IgG1 monoclonal antibody which binds to the human TIGIT receptor on immune cells for the Treatment of advanced solid tumors; and Acumapimod, a p38 MAP kinase inhibitor that is in Phase II clinical trials to treat acute exacerbations of chronic obstructive pulmonary disease. The company has a license agreement with Feng Biosciences for the development and commercialization of navicixizumab; license agreement with ReproNovo for the development and commercialization of leflutrozole; and licensing agreement with AstraZeneca. Mereo BioPharma Group plc was incorporated in 2015 and is headquartered in London, United Kingdom.
Long Name Mereo BioPharma Group plc
Market us_market
Market Cap 53,726,664
Market State CLOSED
Max Age 86,400
Message Board Id finmb_307970474
Most Recent Quarter 1,767,139,200
Net Income To Common -41,878,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 53,726,665
Number Of Analyst Opinions 6
Open 0.3327
Operating Cashflow -30,971,000
Operating Margins -77.114
Payout Ratio 0.0
Phone 44 33 3023 7300
Post Market Change -0.006099999
Post Market Change Percent -1.8122396
Post Market Price 0.3305
Post Market Time 1,776,470,184
Previous Close 0.3263
Price Eps Current Year -12.021428
Price Hint 4
Price To Book 1.3097277
Price To Sales Trailing12 Months 107.45333
Profit Margins 0.0
Quick Ratio 9.99
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key none
Region US
Regular Market Change 0.0103
Regular Market Change Percent 3.15661
Regular Market Day High 0.34
Regular Market Day Low 0.32
Regular Market Day Range 0.32 - 0.34
Regular Market Open 0.3327
Regular Market Previous Close 0.3263
Regular Market Price 0.3366
Regular Market Time 1,776,456,001
Regular Market Volume 2,101,899
Return On Assets -0.39406
Return On Equity -0.82206
Revenue Per Share 0.003
Sand P52 Week Change 0.38150132
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 159,615,766
Shares Percent Shares Out 0.0683
Shares Short 10,907,448
Shares Short Previous Month Date 1,772,150,400
Shares Short Prior Month 13,764,845
Short Name Mereo BioPharma Group plc
Short Percent Of Float 0.084
Short Ratio 7.65
Source Interval 15
Symbol MREO
Target High Price 3.033117
Target Low Price 0.50146455
Target Mean Price 1.769994
Target Median Price 1.5212892
Total Cash 40,992,000
Total Cash Per Share 0.051
Total Debt 202,000
Total Revenue 500,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -0.25
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 1.335695
Two Hundred Day Average Change -0.999095
Two Hundred Day Average Change Percent -0.7479964
Type Disp Equity
Volume 2,101,899
Website https://www.mereobiopharma.com
Zip W1G 0QF