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Monopar Therapeutics Inc. (MNPR)

Healthcare | Biotechnology | Wilmette, United States | NasdaqCM
71.80 USD -1.30 (-1.778%) ⇩ (Oct. 15, 2026, 4 p.m. EDT)
After hours: 71.80

Short-term:★☆☆☆☆Long-term:★★⯪☆☆Dividends:☆☆☆☆☆
Hot Take ↕ | Oct. 10, 2026, 10:07 a.m. EDT

The immediate outlook is severely clouded by aggressive selling pressure; the stock has tumbled from $96.63 to $78.96 over the last two weeks, erasing nearly 20% of its value in mere days. This sharp decline suggests a lack of near-term catalysts to arrest the momentum, despite the broader market's recent recovery. While the long-term picture tells a different story—driven by a spectacular 1,598% surge in the latest fiscal year and a massive 234% gain over the five-year window—the current price action indicates the market is currently pricing in significant uncertainty regarding the company's ability to sustain this growth or manage its cash burn. The disconnect between the soaring long-term trajectory and the precipitous short-term drop creates a volatile environment where the immediate trend is decisively downward, overshadowing the potential for a rebound until clearer signs of stabilization emerge.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoETS ✓0.078564
MSTL0.084236
AutoTheta0.200573
AutoARIMA0.303890

Forecast horizon: 45 days | Selected: AutoETS

Forecast Reliability
Score 28%
H-stat 1.62
Ljung-Box p 0.000
Jarque-Bera p 0.000
Excess Kurtosis 1.57
Attribute Value
Sector Healthcare
Debt to Equity Ratio 0.157
Market Cap 481,933,984
Forward P/E -37.48
Beta 1.51
Website https://www.monopartx.com

Info Dump

Attribute Value
52 Week Change -0.11458331
Address1 1,000 Skokie Boulevard
Address2 Suite 350
All Time High 240.0
All Time Low 1.37
Ask 75.0
Ask Size 1
Audit Risk 9
Average Daily Volume10 Day 160,520
Average Daily Volume3 Month 206,973
Average Volume 206,973
Average Volume10Days 160,520
Beta 1.513
Bid 73.9
Bid Size 5
Board Risk 10
Book Value 19.495
City Wilmette
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 10
Country United States
Crypto Tradeable 0
Currency USD
Current Price 71.8
Current Ratio 33.556
Custom Price Alert Confidence HIGH
Date Short Interest 1,790,726,400
Day High 73.28
Day Low 70.05
Debt To Equity 0.157
Display Name Monopar Therapeutics
Dividend Yield 0.0
Earnings Timestamp 1,786,561,200
Earnings Timestamp End 1,794,510,000
Earnings Timestamp Start 1,794,510,000
Ebitda Margins 0.0
Enterprise Value 347,840,640
Eps Current Year -3.0405
Eps Forward -1.91575
Eps Trailing Twelve Months -2.2
Esg Populated 0
Exchange NCM
Exchange Data Delayed By 15
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 101.8321
Fifty Day Average Change -30.032097
Fifty Day Average Change Percent -0.2949178
Fifty Two Week Change Percent -11.458331
Fifty Two Week High 124.82
Fifty Two Week High Change -53.019997
Fifty Two Week High Change Percent -0.42477164
Fifty Two Week Low 50.07
Fifty Two Week Low Change 21.730003
Fifty Two Week Low Change Percent 0.43399248
Fifty Two Week Range 50.07 - 124.82
Financial Currency USD
First Trade Date Milliseconds 1,576,765,800,000
Float Shares 4,467,219
Forward Eps -1.91575
Forward P E -37.478794
Free Cashflow -6,098,616
Full Exchange Name NasdaqCM
Full Time Employees 22
Fullday Change -1.2999954
Fullday Change Percent -1.7783796
Fullday Price 71.8
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,790,812,800
Gross Margins 0.0
Has Pre Post Market Data 1
Held Percent Insiders 0.23472
Held Percent Institutions 0.94908
Implied Shares Outstanding 6,712,172
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Last Split Date 1,723,507,200
Last Split Factor 1:5
Long Business Summary Monopar Therapeutics Inc., a clinical-stage biopharmaceutical company, engages in developing therapeutics for the treatment of cancer in the United States. The company develops ALXN1840, a late-stage, investigational once-daily and oral medicine; MNPR-101, a proprietary humanized monoclonal antibody that is conjugated with different radioisotopes for the treatment of advanced solid tumors expressing urokinase plasminogen activator receptor; and MNPR-101-Zr, which is in phase 1 imaging and dosimetry clinical trial, a radiopharmaceutical imaging agent comprised of MNPR-101 conjugated to zirconium-89. It develops MNPR-101-Lu, a Phase1a stage radiotherapeutic comprised of MNPR-101 conjugated to actinium-225. The company has collaborations NorthStar to develop radio-immuno-therapeutics targeting severe COVID-19; Excel Diagnostics and Nuclear Oncology Center, for the investigational imaging agent MNPR-101-Zr and investigational therapeutic agent MNPR-101-Lu; license agreement with Alexion to develop and commercialize ALXN1840, a drug candidate for Wilson disease. The company was founded in 2014 and is headquartered in Wilmette, Illinois.
Long Name Monopar Therapeutics Inc.
Market us_market
Market Cap 481,933,984
Market State POSTPOST
Max Age 86,400
Message Board Id finmb_304391755
Most Recent Quarter 1,782,777,600
Net Income To Common -17,844,746
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 597,584,673
Number Of Analyst Opinions 12
Open 73.2
Operating Cashflow -12,181,947
Operating Margins 0.0
Overall Risk 9
Phone 847 388 0349
Post Market Change 0.0
Post Market Change Percent 0.0
Post Market Price 71.8
Post Market Time 1,792,094,436
Previous Close 73.1
Price Eps Current Year -23.614538
Price Hint 2
Price To Book 3.6829956
Profit Margins 0.0
Quick Ratio 33.441
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key none
Region US
Regular Market Change -1.3
Regular Market Change Percent -1.77838
Regular Market Day High 73.28
Regular Market Day Low 70.05
Regular Market Day Range 70.05 - 73.28
Regular Market Open 73.2
Regular Market Previous Close 73.1
Regular Market Price 71.8
Regular Market Time 1,792,094,401
Regular Market Volume 139,378
Return On Assets -0.1464
Return On Equity -0.19496
Sand P52 Week Change 0.16440773
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 2
Shares Outstanding 6,712,172
Shares Percent Shares Out 0.1618
Shares Short 1,086,279
Shares Short Previous Month Date 1,788,134,400
Shares Short Prior Month 852,425
Short Name Monopar Therapeutics Inc.
Short Percent Of Float 0.2369
Short Ratio 7.15
Source Interval 15
State IL
Symbol MNPR
Target High Price 145.0
Target Low Price 119.0
Target Mean Price 129.91667
Target Median Price 130.0
Total Cash 134,298,976
Total Cash Per Share 20.008
Total Debt 205,663
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -2.2
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 76.8235
Two Hundred Day Average Change -5.0234985
Two Hundred Day Average Change Percent -0.065390125
Type Disp Equity
Volume 139,378
Website https://www.monopartx.com
Zip 60,091