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Milestone Pharmaceuticals Inc. (MIST)

Healthcare | Biotechnology | Montreal, Canada | NasdaqGS
2.10 USD +0.01 (0.478%) ⇧ (April 17, 2026, 4 p.m. EDT)
After hours: 2.10

Short-term: ★★★★★ | Long-term: ★★★☆☆ | Dividends: ★★☆☆☆
Hot Take | April 18, 2026, 11:35 p.m. EDT

MIST is in a high-conviction short-term breakout phase driven by positive catalysts (analyst upgrades, earnings beat) and aggressive call speculation, but long-term value remains subjective due to persistent losses and no current dividend infrastructure.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
MSTL ✓0.189089
AutoARIMA0.193771
AutoETS0.193772
AutoTheta0.208405

Forecast horizon: 45 days | Selected: MSTL

Forecast Reliability
Score 21%
H-stat 20.24
Ljung-Box p 0.000
Jarque-Bera p 0.001
Excess Kurtosis 0.93
Attribute Value
Sector Healthcare
Debt to Equity Ratio 139.762
Revenue per Share 0.018
Market Cap 247,101,280
Forward P/E -2.46
Beta 0.69
Website https://www.milestonepharma.com

As of April 18, 2026, 11:35 p.m. EDT: Speculative sentiment is heavily skewed bullish with significant Call positioning relative to Puts. The 2026-05-15 expiration sees the highest volume of out-of-the-money (OTM) calls (474 contracts) compared to negligible put volume (2), indicating a strong momentum buy program. Despite higher implied volatility in Puts for near-term expirations (1.91 IV) versus Calls (1.19 IV) at the April 17 strike, the sheer volume of Calls at May and June expirations suggests traders are positioning for a move above current levels (OTM OI % combined is significantly higher for Calls). The presence of Iron Condors (OTM Puts with volume) at May and June strikes suggests traders are offering downside protection at elevated prices, betting on a continued rally or a sharp, short-term bottoming out followed by upside.


Info Dump

Attribute Value
52 Week Change 1.0792079
Address1 1,111 Dr. Frederik-Philips Boulevard
Address2 Suite 420
All Time High 27.95
All Time Low 0.625
Ask 2.14
Ask Size 51
Average Analyst Rating 1.5 - Strong Buy
Average Daily Volume10 Day 3,677,780
Average Daily Volume3 Month 2,256,849
Average Volume 2,256,849
Average Volume10Days 3,677,780
Beta 0.685
Bid 2.09
Bid Size 34
Book Value 0.341
City Montreal
Compensation As Of Epoch Date 1,735,603,200
Country Canada
Crypto Tradeable 0
Currency USD
Current Price 2.1
Current Ratio 8.006
Custom Price Alert Confidence HIGH
Date Short Interest 1,774,915,200
Day High 2.16
Day Low 2.05
Debt To Equity 139.762
Display Name Milestone Pharmaceuticals
Earnings Call Timestamp End 1,774,009,800
Earnings Call Timestamp Start 1,774,009,800
Earnings Timestamp 1,774,009,800
Earnings Timestamp End 1,778,761,800
Earnings Timestamp Start 1,778,761,800
Ebitda -62,026,000
Ebitda Margins 0.0
Enterprise To Ebitda 0.211
Enterprise To Revenue -8.484
Enterprise Value -13,115,858
Eps Current Year -0.645
Eps Forward -0.855
Eps Trailing Twelve Months -0.75
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 1.6574
Fifty Day Average Change 0.4425999
Fifty Day Average Change Percent 0.2670447
Fifty Two Week Change Percent 107.92079
Fifty Two Week High 3.06
Fifty Two Week High Change -0.96000004
Fifty Two Week High Change Percent -0.3137255
Fifty Two Week Low 0.88
Fifty Two Week Low Change 1.2199999
Fifty Two Week Low Change Percent 1.3863635
Fifty Two Week Range 0.88 - 3.06
Financial Currency USD
First Trade Date Milliseconds 1,557,408,600,000
Float Shares 14,061,117
Forward Eps -0.855
Forward P E -2.4561403
Free Cashflow -28,903,250
Full Exchange Name NasdaqGS
Full Time Employees 38
Gmt Off Set Milliseconds -14,400,000
Gross Margins 1.0
Gross Profits 1,546,000
Has Pre Post Market Data 1
Held Percent Insiders 0.02398
Held Percent Institutions 0.27124
Implied Shares Outstanding 117,667,278
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Milestone Pharmaceuticals Inc., a biopharmaceutical company, focuses on the development and commercialization of cardiovascular medicines in the United States and Canada. It offers CARDAMYST (etripamil) nasal spray, a prescription medication for the conversion of acute symptomatic episodes of paroxysmal supraventricular tachycardia (PSVT) to sinus rhythm in adults. The company is also developing etripamil for the indication of atrial fibrillation with rapid ventricular rate (AFib-RVR). It has a license and collaboration agreement with Corxel Pharmaceuticals to develop and commercialize etripamil. Milestone Pharmaceuticals Inc.was incorporated in 2003 and is headquartered in Montreal, Canada.
Long Name Milestone Pharmaceuticals Inc.
Market us_market
Market Cap 247,101,280
Market State CLOSED
Max Age 86,400
Message Board Id finmb_36171059
Most Recent Quarter 1,767,139,200
Net Income To Common -63,058,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 248,277,954
Number Of Analyst Opinions 6
Open 2.12
Operating Cashflow -49,041,000
Operating Margins -11.16235
Payout Ratio 0.0
Phone 514 336 0444
Post Market Change 0.0
Post Market Change Percent 0.0
Post Market Price 2.1
Post Market Time 1,776,465,438
Previous Close 2.09
Price Eps Current Year -3.2558138
Price Hint 4
Price To Book 6.1583576
Price To Sales Trailing12 Months 159.83266
Profit Margins 0.0
Quick Ratio 7.831
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.5
Region US
Regular Market Change 0.00999999
Regular Market Change Percent 0.478468
Regular Market Day High 2.16
Regular Market Day Low 2.05
Regular Market Day Range 2.05 - 2.16
Regular Market Open 2.12
Regular Market Previous Close 2.09
Regular Market Price 2.1
Regular Market Time 1,776,456,001
Regular Market Volume 1,278,004
Return On Assets -0.41085
Return On Equity -2.29653
Revenue Per Share 0.018
Sand P52 Week Change 0.38150132
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 117,667,277
Shares Percent Shares Out 0.0718
Shares Short 8,453,485
Shares Short Previous Month Date 1,772,150,400
Shares Short Prior Month 8,424,060
Short Name Milestone Pharmaceuticals Inc.
Short Percent Of Float 0.0718
Short Ratio 4.14
Source Interval 15
State QC
Symbol MIST
Target High Price 8.0
Target Low Price 2.0
Target Mean Price 6.5
Target Median Price 7.5
Total Cash 105,960,000
Total Cash Per Share 6.456
Total Debt 58,377,000
Total Revenue 1,546,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -0.75
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 1.886725
Two Hundred Day Average Change 0.21327496
Two Hundred Day Average Change Percent 0.11303977
Type Disp Equity
Volume 1,278,004
Website https://www.milestonepharma.com
Zip H4M 2X6