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Mirum Pharmaceuticals, Inc. (MIRM)

Healthcare | Biotechnology | Foster City, United States | NasdaqGM
119.04 USD -3.09 (-2.530%) ⇩ (July 13, 2026, 4 p.m. EDT)

Short-term:★★★★☆Long-term:★★★☆☆Dividends:☆☆☆☆☆
Hot Take | July 11, 2026, 5:48 a.m. EDT

Mirum Pharmaceuticals is riding a powerful momentum wave, surging nearly 13% in just two weeks as retail investors eye a potential buyout premium following positive liver disease trial data. While the stock trades near its 52-week high, the underlying business remains a high-risk biotech play with negative earnings and significant operating losses. The strong revenue growth of 43% supports the valuation, yet the lack of profitability and high debt load prevent a top-tier long-term rating. Options flow confirms the speculative appetite, with call buyers targeting upside beyond current levels, though deep put protection exists for later dates. For now, the technicals and catalyst-driven news outweigh the fundamental risks, making it a compelling short-term trade, but investors should remain cautious about the binary nature of clinical outcomes.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoARIMA ✓0.069755
AutoTheta0.075132
MSTL_97_1260.076586
MSTL_970.081944
MSTL0.082883
AutoETS0.085029
MSTL_1260.086542

Forecast horizon: 60 days | Selected: AutoARIMA

Forecast Reliability
Score 37%
H-stat 5.40
Ljung-Box p 0.000
Jarque-Bera p 0.092
Excess Kurtosis -0.79
Attribute Value
Sector Healthcare
Debt to Equity Ratio 133.52
Revenue per Share 10.811
Market Cap 7,259,205,632
Forward P/E -633.19
Beta 0.49
Profit Margins -140.24%
Website https://www.mirumpharma.com

As of July 11, 2026, 5:48 a.m. EDT: Speculators are positioning for volatility with elevated implied volatility across expirations. Call positioning leans bullish in the near-to-intermediate term, with significant open interest at strikes above the current price (130, 135, 180), while put activity concentrates on deep out-of-the-money strikes further out, suggesting a hedge against downside rather than a primary bet on collapse. The mix indicates a speculative bias toward upside continuation.


Info Dump

Attribute Value
52 Week Change 1.2901115
Address1 989 East Hillsdale Boulevard
Address2 Suite 300
All Time High 130.0
All Time Low 6.513
Ask 151.37
Ask Size 2
Audit Risk 6
Average Analyst Rating 1.3 - Strong Buy
Average Daily Volume10 Day 797,740
Average Daily Volume3 Month 1,002,395
Average Volume 1,002,395
Average Volume10Days 797,740
Beta 0.485
Bid 85.99
Bid Size 2
Board Risk 10
Book Value 3.98
City Foster City
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 7
Country United States
Crypto Tradeable 0
Currency USD
Current Price 119.04
Current Ratio 2.087
Custom Price Alert Confidence HIGH
Date Short Interest 1,782,777,600
Day High 120.89
Day Low 117.18
Debt To Equity 133.52
Display Name Mirum Pharmaceuticals
Earnings Call Timestamp End 1,778,099,400
Earnings Call Timestamp Start 1,778,099,400
Earnings Timestamp 1,778,097,600
Earnings Timestamp End 1,785,960,000
Earnings Timestamp Start 1,785,960,000
Ebitda -50,050,000
Ebitda Margins -0.087869994
Enterprise To Ebitda -143.791
Enterprise To Revenue 12.635
Enterprise Value 7,196,725,248
Eps Current Year -14.24
Eps Forward -0.188
Eps Trailing Twelve Months -13.26
Esg Populated 0
Exchange NGM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 106.2944
Fifty Day Average Change 12.745598
Fifty Day Average Change Percent 0.11990846
Fifty Two Week Change Percent 129.01115
Fifty Two Week High 130.0
Fifty Two Week High Change -10.959999
Fifty Two Week High Change Percent -0.084307685
Fifty Two Week Low 50.25
Fifty Two Week Low Change 68.79
Fifty Two Week Low Change Percent 1.3689553
Fifty Two Week Range 50.25 - 130.0
Financial Currency USD
First Trade Date Milliseconds 1,563,456,600,000
Float Shares 52,463,979
Forward Eps -0.188
Forward P E -633.1915
Free Cashflow 166,895,872
Full Exchange Name NasdaqGM
Full Time Employees 418
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,782,864,000
Gross Margins 0.81386
Gross Profits 463,582,016
Has Pre Post Market Data 1
Held Percent Insiders 0.013890001
Held Percent Institutions 1.14382
Implied Shares Outstanding 60,981,227
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Mirum Pharmaceuticals, Inc., a biopharmaceutical company, focuses on the development and commercialization of novel therapies for debilitating rare and orphan diseases. Its lead product candidate is LIVMARLI (maralixibat), an orally administered and minimally absorbed ileal bile acid transporter (IBAT) inhibitor that is approved for the treatment of cholestatic pruritus in patients with Alagille syndrome in the United States and internationally. The company is also involved in the commercialization of Cholbam, a cholic acid capsule, which is approved as treatment for pediatric and adult patients with bile acid synthesis disorders due to single enzyme defects and for adjunctive treatment of patients with peroxisomal disorders, including peroxisome biogenesis disorder-Zellweger spectrum disorder and Smith-Lemli-Opitz syndrome; and Chenodal, a tablet, which is approved for the treatment of radiolucent stones in the gallbladder, and under development for the treatment cerebrotendinous xanthomatosis. In addition, it develops Volixibat, an oral and minimally absorbed agent designed to inhibit IBAT, currently under Phase 2b clinical trial for the treatment of adult patients with cholestatic liver diseases; Brelovitug, for the treatment of chronic HDV infection, which is in Phase 2 clinical trial; and MRM-3379, that is in Phase 2 clinical study for the treatment of FXS. The company has a collaboration agreement with the Shire International GmbH; License Agreement with Pfizer Inc.; Sanofi-Aventis Deutschland GmbH; Novartis Pharma AG; Lonza Ltd.; Enthorin Therapeutics, LLC and Dart Neuroscience LLC; Asset Purchase Agreement with Asklepion Pharmaceuticals, LLC; License and Manufacturing Agreement with LGM Pharma; and Asset Purchase Agreement with Travere Therapeutics, Inc. The company was incorporated in 2018 and is headquartered in Foster City, California.
Long Name Mirum Pharmaceuticals, Inc.
Market us_market
Market Cap 7,259,205,632
Market State PRE
Max Age 86,400
Message Board Id finmb_590571226
Most Recent Quarter 1,774,915,200
Net Income To Common -798,841,024
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 7,259,205,262
Number Of Analyst Opinions 14
Open 120.85
Operating Cashflow -170,975,008
Operating Margins -0.39506
Overall Risk 9
Payout Ratio 0.0
Phone 650 667 4085
Pre Market Change 0.94999695
Pre Market Change Percent 0.7980485
Pre Market Price 119.99
Pre Market Time 1,784,031,494
Previous Close 122.13
Price Eps Current Year -8.35955
Price Hint 2
Price To Book 29.909548
Price To Sales Trailing12 Months 12.74419
Profit Margins -1.4024401
Quick Ratio 1.904
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.28571
Region US
Regular Market Change -3.09
Regular Market Change Percent -2.53009
Regular Market Day High 120.89
Regular Market Day Low 117.18
Regular Market Day Range 117.18 - 120.89
Regular Market Open 120.85
Regular Market Previous Close 122.13
Regular Market Price 119.04
Regular Market Time 1,783,972,801
Regular Market Volume 525,373
Return On Assets -0.059380002
Return On Equity -3.3582401
Revenue Growth 0.433
Revenue Per Share 10.811
Sand P52 Week Change 0.20365608
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 8
Shares Outstanding 60,981,227
Shares Percent Shares Out 0.122700006
Shares Short 7,483,286
Shares Short Previous Month Date 1,780,012,800
Shares Short Prior Month 6,561,290
Short Name Mirum Pharmaceuticals, Inc.
Short Percent Of Float 0.161
Short Ratio 7.16
Source Interval 15
State CA
Symbol MIRM
Target High Price 185.0
Target Low Price 125.0
Target Mean Price 146.5
Target Median Price 145.0
Total Cash 386,259,008
Total Cash Per Share 6.334
Total Debt 323,779,008
Total Revenue 569,609,024
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -13.26
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 89.58682
Two Hundred Day Average Change 29.453178
Two Hundred Day Average Change Percent 0.32876685
Type Disp Equity
Volume 525,373
Website https://www.mirumpharma.com
Zip 94,404