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Mirum Pharmaceuticals, Inc. (MIRM)

Healthcare | Biotechnology | Foster City, United States | NasdaqGM
94.37 USD -1.35 (-1.405%) ⇩ (April 21, 2026, 12:33 p.m. EDT)

Short-term: ★★☆☆☆ | Long-term: ★★★☆☆ | Dividends: ☆☆☆☆☆
Hot Take | April 19, 2026, 1:47 a.m. EDT

Mirum Pharmaceuticals (MIRM) faces a stark divergence between analyst optimism (Strong Buy consensus, 11 opinions, $125 target) and aggressive short-term hedging. While the company shows exceptional revenue growth (nearly 50% in 22Q4) and has finally posted GAAP profit, the options market is pricing in a non-trivial downside event before the market can rally to the $120+ analysts expect. The heavy put volume at the 80 strike acts as a formidable technical support floor; breaking below this level could trigger a re-rating from 'growth stock' to 'value trap' in the near term, while holding above it offers a high-reward path to the mean. For immediate entry, the technicals are overextended short-term despite the strong fundamental narrative.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoETS ✓0.060408
AutoARIMA0.060409
MSTL0.061523
AutoTheta0.136235

Forecast horizon: 45 days | Selected: AutoETS

Forecast Reliability
Score 57%
H-stat 2.30
Ljung-Box p 0.000
Jarque-Bera p 0.241
Excess Kurtosis -1.16
Attribute Value
Sector Healthcare
Debt to Equity Ratio 101.513
Revenue per Share 10.385
Market Cap 5,694,136,320
Forward P/E -869.16
Beta 0.52
Profit Margins -4.48%
Website https://www.mirumpharma.com

As of April 19, 2026, 1:47 a.m. EDT: Options positioning reveals a bearish skew for the immediate future (May/July 2026). Put volume (1,200 contracts) significantly outweighs call volume (1,200 contracts total but concentrated heavily at lower strikes like 80/85). Specifically, May 15th shows massive put buying at the 80 and 90 strikes compared to negligible lottery on calls below 95. This institutional retail positioning suggests a high probability of a downside move targeting the 75–85 range over the next month before mean reversion or longer-term biotech beta plays out in the year-end calls where calls start gaining interest.


Info Dump

Attribute Value
52 Week Change 1.4273396
Address1 989 East Hillsdale Boulevard
Address2 Suite 300
All Time High 109.28
All Time Low 6.513
Ask 120.46
Ask Size 2
Audit Risk 9
Average Analyst Rating 1.3 - Strong Buy
Average Daily Volume10 Day 589,940
Average Daily Volume3 Month 823,070
Average Volume 823,070
Average Volume10Days 589,940
Beta 0.518
Bid 94.15
Bid Size 1
Board Risk 8
Book Value 6.064
City Foster City
Compensation As Of Epoch Date 1,735,603,200
Compensation Risk 8
Country United States
Crypto Tradeable 0
Currency USD
Current Price 94.365
Current Ratio 2.671
Custom Price Alert Confidence HIGH
Date Short Interest 1,774,915,200
Day High 95.94
Day Low 92.88
Debt To Equity 101.513
Display Name Mirum Pharmaceuticals
Earnings Call Timestamp End 1,772,055,000
Earnings Call Timestamp Start 1,772,055,000
Earnings Timestamp 1,772,053,200
Earnings Timestamp End 1,778,097,600
Earnings Timestamp Start 1,778,097,600
Ebitda 2,108,000
Ebitda Margins 0.00404
Enterprise To Ebitda 2,709.403
Enterprise To Revenue 10.956
Enterprise Value 5,711,420,928
Eps Current Year -1.82571
Eps Forward -0.10857
Eps Trailing Twelve Months -0.47
Esg Populated 0
Exchange NGM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 95.3236
Fifty Day Average Change -0.9586029
Fifty Day Average Change Percent -0.010056302
Fifty Two Week Change Percent 142.73395
Fifty Two Week High 109.28
Fifty Two Week High Change -14.915001
Fifty Two Week High Change Percent -0.13648427
Fifty Two Week Low 38.33
Fifty Two Week Low Change 56.034996
Fifty Two Week Low Change Percent 1.4619095
Fifty Two Week Range 38.33 - 109.28
Financial Currency USD
First Trade Date Milliseconds 1,563,456,600,000
Float Shares 52,434,452
Forward Eps -0.10857
Forward P E -869.1627
Free Cashflow 98,558,872
Full Exchange Name NasdaqGM
Full Time Employees 369
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,775,001,600
Gross Margins 0.80772
Gross Profits 421,072,000
Has Pre Post Market Data 1
Held Percent Insiders 0.01327
Held Percent Institutions 1.04747
Implied Shares Outstanding 60,341,617
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Mirum Pharmaceuticals, Inc., a biopharmaceutical company, focuses on the development and commercialization of novel therapies for debilitating rare and orphan diseases. Its lead product candidate is LIVMARLI (maralixibat), an orally administered and minimally absorbed ileal bile acid transporter (IBAT) inhibitor that is approved for the treatment of cholestatic pruritus in patients with Alagille syndrome in the United States and internationally. The company is also involved in the commercialization of Cholbam, a cholic acid capsule, which is approved as treatment for pediatric and adult patients with bile acid synthesis disorders due to single enzyme defects and for adjunctive treatment of patients with peroxisomal disorders, including peroxisome biogenesis disorder-Zellweger spectrum disorder and Smith-Lemli-Opitz syndrome; and Chenodal, a tablet, which is approved for the treatment of radiolucent stones in the gallbladder, and under development for the treatment cerebrotendinous xanthomatosis. In addition, it develops Volixibat, an oral and minimally absorbed agent designed to inhibit IBAT, currently under Phase 2b clinical trial for the treatment of adult patients with cholestatic liver diseases; Brelovitug, for the treatment of chronic HDV infection, which is in Phase 2 clinical trial; and MRM-3379, that is in Phase 2 clinical study for the treatment of FXS. The company has a collaboration agreement with the Shire International GmbH; License Agreement with Pfizer Inc.; Sanofi-Aventis Deutschland GmbH; Novartis Pharma AG; Lonza Ltd.; Enthorin Therapeutics, LLC and Dart Neuroscience LLC; Asset Purchase Agreement with Asklepion Pharmaceuticals, LLC; License and Manufacturing Agreement with LGM Pharma; and Asset Purchase Agreement with Travere Therapeutics, Inc. The company was incorporated in 2018 and is headquartered in Foster City, California.
Long Name Mirum Pharmaceuticals, Inc.
Market us_market
Market Cap 5,694,136,320
Market State REGULAR
Max Age 86,400
Message Board Id finmb_590571226
Most Recent Quarter 1,767,139,200
Net Income To Common -23,363,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 5,781,933,740
Number Of Analyst Opinions 11
Open 95.08
Operating Cashflow 55,827,000
Operating Margins -0.030669998
Overall Risk 8
Payout Ratio 0.0
Phone 650 667 4085
Previous Close 95.71
Price Eps Current Year -51.686737
Price Hint 2
Price To Book 15.56151
Price To Sales Trailing12 Months 10.922704
Profit Margins -0.04482
Quick Ratio 2.462
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.27273
Region US
Regular Market Change -1.3450012
Regular Market Change Percent -1.4052881
Regular Market Day High 95.94
Regular Market Day Low 92.88
Regular Market Day Range 92.88 - 95.94
Regular Market Open 95.08
Regular Market Previous Close 95.71
Regular Market Price 94.365
Regular Market Time 1,776,789,204
Regular Market Volume 126,248
Return On Assets -0.01828
Return On Equity -0.08648
Revenue Growth 0.498
Revenue Per Share 10.385
Sand P52 Week Change 0.34445214
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 8
Shares Outstanding 60,341,617
Shares Percent Shares Out 0.13340001
Shares Short 8,050,414
Shares Short Previous Month Date 1,772,150,400
Shares Short Prior Month 7,623,019
Short Name Mirum Pharmaceuticals, Inc.
Short Percent Of Float 0.13340001
Short Ratio 7.81
Source Interval 15
State CA
Symbol MIRM
Target High Price 140.0
Target Low Price 95.0
Target Mean Price 125.36364
Target Median Price 128.0
Total Cash 383,327,008
Total Cash Per Share 6.353
Total Debt 319,452,000
Total Revenue 521,312,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -0.47
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 77.77605
Two Hundred Day Average Change 16.588951
Two Hundred Day Average Change Percent 0.21329126
Type Disp Equity
Volume 126,248
Website https://www.mirumpharma.com
Zip 94,404