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Mesoblast Limited (MESO)

Healthcare | Biotechnology | Melbourne, Australia | NasdaqGS
18.16 USD +1.42 (8.453%) ⇧ (July 15, 2026, 10:20 a.m. EDT)

Short-term:★★☆☆☆Long-term:★★☆☆☆Dividends:☆☆☆☆☆
Hot Take | July 11, 2026, 5:49 a.m. EDT

The investment case for Mesoblast is currently bifurcated between a compelling catalyst-driven trade and a fundamentally distressed biotech profile. On the short end, the market is pricing in a major event: the company's Rexlemestrocel-L product has entered FDA modular review, a critical milestone that could unlock significant value. This is corroborated by the options chain, where traders are aggressively buying calls at strikes well above the current price, betting on a rapid re-rating upon regulatory approval. However, the long-term outlook remains precarious. The company is burning cash rapidly, with negative operating cash flow and gross margins, and relies entirely on future drug approvals for survival. While the revenue growth rate is positive, the absolute scale is negligible, and the balance sheet is fragile. The lack of a dividend and the high volatility inherent in pre-revenue biotech stocks suggest that while the risk/reward ratio is attractive for a tactical play on the FDA decision, the underlying business quality does not yet support a permanent hold at these valuations.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoTheta ✓0.043800
AutoETS0.043812
AutoARIMA0.043812
MSTL_790.048827
MSTL0.049690
MSTL_970.067134
MSTL_79_970.090119

Forecast horizon: 60 days | Selected: AutoTheta

Forecast Reliability
Score 37%
H-stat 0.46
Ljung-Box p 0.000
Jarque-Bera p 0.630
Excess Kurtosis -0.61
Attribute Value
Sector Healthcare
Debt to Equity Ratio 23.516
Revenue per Share 0.51
Market Cap 2,347,124,736
Forward P/E -302.58
Beta 0.80
Profit Margins -144.33%
Website https://www.mesoblast.com

As of July 11, 2026, 5:49 a.m. EDT: Speculators are positioning for a significant upside move, evidenced by heavy open interest in out-of-the-money calls at strikes of 18 and 25 for the July expiration, and substantial long-dated call volume at strikes of 20 and 25. Conversely, put activity is concentrated near the money or slightly out-of-the-money, suggesting a defensive stance rather than a bearish bet. The skew indicates a speculative expectation of a rally driven by the FDA review progress.


Info Dump

Attribute Value
52 Week Change 0.47488987
Address1 55 Collins Street
Address2 Level 38
All Time High 106.34
All Time Low 1.61
Ask 22.45
Ask Size 2
Average Analyst Rating 1.7 - Buy
Average Daily Volume10 Day 250,270
Average Daily Volume3 Month 188,072
Average Volume 188,072
Average Volume10Days 250,270
Beta 0.798
Bid 12.96
Bid Size 2
Book Value 4.46
City Melbourne
Compensation As Of Epoch Date 1,767,139,200
Country Australia
Crypto Tradeable 0
Currency USD
Current Price 18.155
Current Ratio 1.581
Custom Price Alert Confidence HIGH
Date Short Interest 1,782,777,600
Day High 18.25
Day Low 17.53
Debt To Equity 23.516
Earnings Call Timestamp End 1,772,143,200
Earnings Call Timestamp Start 1,772,143,200
Earnings Timestamp End 1,772,139,600
Earnings Timestamp Start 1,772,139,600
Ebitda -64,339,000
Ebitda Margins -0.98402
Enterprise To Ebitda -33.605
Enterprise To Revenue 33.068
Enterprise Value 2,162,142,976
Eps Current Year -0.475
Eps Forward -0.06
Eps Trailing Twelve Months -0.79
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fax 61 3 9639 6030
Fifty Day Average 14.7036
Fifty Day Average Change 3.4514008
Fifty Day Average Change Percent 0.23473169
Fifty Two Week Change Percent 47.488987
Fifty Two Week High 21.5
Fifty Two Week High Change -3.3449993
Fifty Two Week High Change Percent -0.15558137
Fifty Two Week Low 11.05
Fifty Two Week Low Change 7.1050005
Fifty Two Week Low Change Percent 0.6429865
Fifty Two Week Range 11.05 - 21.5
Financial Currency USD
First Trade Date Milliseconds 1,263,997,800,000
Float Shares 83,383,668
Forward Eps -0.06
Forward P E -302.58334
Free Cashflow -69,438,336
Full Exchange Name NasdaqGS
Full Time Employees 81
Gmt Off Set Milliseconds -14,400,000
Gross Margins -0.35535
Gross Profits -23,234,000
Has Pre Post Market Data 1
Held Percent Insiders 0.050419997
Held Percent Institutions 0.02799
Implied Shares Outstanding 129,282,554
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 0
Language en-US
Last Fiscal Year End 1,751,241,600
Last Split Date 1,704,844,800
Last Split Factor 1:2
Long Business Summary Mesoblast Limited, together with its subsidiaries, engages in the development of regenerative medicine products in Australia, the United States, Singapore, and Switzerland. The company's proprietary regenerative medicine technology platform is based on specialized cells known as mesenchymal lineage cells. It offers Remestemcel-L, which is in Phase III clinical trials for the treatment of systemic inflammatory diseases, including steroid refractory acute graft versus host disease and biologic refractory inflammatory bowel disease, as well as ulcerative colitis and Crohn's disease; and Remestemcel-L, which is in Phase III clinical trials to treat chronic heart failure and chronic low back pain due to degenerative disc disease. The company is also developing MPC-300-IV to treat biologic refractory rheumatoid arthritis diabetic nephropathy. It has strategic partnerships with Tasly Pharmaceutical Group to offer MPC-150-IM for the treatment or prevention of chronic heart failure; MPC-25-IC for the treatment or prevention of acute myocardial infarction; and Ryoncil for the treatment of pediatric SR-aGVHD; JCR Pharmaceuticals Co. Ltd. to treat wound healing in patients with epidermolysis bullosa and for the treatment of neonatal hypoxic ischemic encephalopathy; and Grünenthal to develops and commercializes cell therapy for the treatment of chronic low back pain. The company was incorporated in 2004 and is headquartered in Melbourne, Australia.
Long Name Mesoblast Limited
Market us_market
Market Cap 2,347,124,736
Market State REGULAR
Max Age 86,400
Message Board Id finmb_20356678
Most Recent Quarter 1,767,139,200
Net Income To Common -94,370,000
Next Fiscal Year End 1,782,777,600
Non Diluted Market Cap 2,120,924,446
Number Of Analyst Opinions 2
Open 17.54
Operating Cashflow -59,643,000
Operating Margins -0.55158
Payout Ratio 0.0
Phone 61 3 9639 6036
Previous Close 16.74
Price Eps Current Year -38.221054
Price Hint 2
Price To Book 4.0706277
Price To Sales Trailing12 Months 35.89754
Profit Margins -1.44332
Quick Ratio 1.353
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key buy
Recommendation Mean 1.66667
Region US
Regular Market Change 1.4150009
Regular Market Change Percent 8.452813
Regular Market Day High 18.25
Regular Market Day Low 17.53
Regular Market Day Range 17.53 - 18.25
Regular Market Open 17.54
Regular Market Previous Close 16.74
Regular Market Price 18.155
Regular Market Time 1,784,125,218
Regular Market Volume 173,290
Return On Assets -0.06163
Return On Equity -0.18219
Revenue Growth 15.268
Revenue Per Share 0.51
Sand P52 Week Change 0.2043345
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 129,282,554
Shares Percent Shares Out 0.024
Shares Short 3,103,325
Shares Short Previous Month Date 1,780,012,800
Shares Short Prior Month 3,061,116
Short Name Mesoblast Limited
Short Percent Of Float 0.032899998
Short Ratio 17.15
Source Interval 15
State VIC
Symbol MESO
Target High Price 35.0
Target Low Price 35.0
Target Mean Price 35.0
Target Median Price 35.0
Total Cash 129,975,000
Total Cash Per Share 1.009
Total Debt 135,144,000
Total Revenue 65,384,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -0.79
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 16.19
Two Hundred Day Average Change 1.9650002
Two Hundred Day Average Change Percent 0.121371225
Type Disp Equity
Volume 173,290
Website https://www.mesoblast.com
Zip 3,000