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Mesoblast Limited (MESO)

Healthcare | Biotechnology | Melbourne, Australia | NasdaqGS
16.46 USD +0.37 (2.300%) ⇧ (April 17, 2026, 4 p.m. EDT)
After hours: 16.78 +0.32 (1.944%) ⇧ (April 17, 2026, 5:07 p.m. EDT)

Short-term: ★★★☆☆ | Long-term: ★☆☆☆☆ | Dividends: ☆☆☆☆☆
Hot Take | April 18, 2026, 11:48 p.m. EDT

MESO is a polarized biotech play warning of a value trap masked by aggressive analyst upgrades. While insiders and tailwinds from new trials (Ryoncil) justify an upcoming catalyst, the fundamentals are in clear distress: negative gross margins, massive debt-to-equity, and an inability to generate free cash flow. The current price ($16.46) sits slightly above the 200-day average, suggesting peripheral resistance. The options market shows a temporary speculative impulse for upside ($17/$18 calls), but this lacks significant volume support, making this a speculative hold-to-catalyst rather than a solvent investment.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoETS ✓0.199084
MSTL0.218570
AutoTheta0.292757
AutoARIMA0.307750

Forecast horizon: 45 days | Selected: AutoETS

Forecast Reliability
Score 48%
H-stat 4.98
Ljung-Box p 0.000
Jarque-Bera p 0.295
Excess Kurtosis -0.96
Attribute Value
Sector Healthcare
Debt to Equity Ratio 23.516
Revenue per Share 0.51
Market Cap 2,154,218,240
Forward P/E -235.14
Beta 0.82
Profit Margins -144.33%
Website https://www.mesoblast.com

As of April 18, 2026, 11:48 p.m. EDT: Speculative positioning leans bullish despite low call volume. In the ~1-month horizon (May '26), Call Open Interest (OI) is heavily skewed out-of-the-money (OTM) at strikes $17.00 and $18.00 (97% OTM OI), signaling a bias toward a bounce or gap-up, slightly outweighing Put OI concentrated at the strike. However, this bullish setup is tentative as total Call volume is negligible compared to the dominant Put positioning in the short-term (noticeable Put OI at $14 and $15). Longer-term (Oct '26+) volume is flat, suggesting the 'bullish' OI in nearer expirations is either early positioning or a 'stop-loss' flip strategy rather than a massive commitment of capital to a long rally.


Info Dump

Attribute Value
52 Week Change 0.6011673
Address1 55 Collins Street
Address2 Level 38
All Time High 106.34
All Time Low 1.61
Ask 21.12
Ask Size 2
Average Analyst Rating 1.7 - Buy
Average Daily Volume10 Day 269,080
Average Daily Volume3 Month 260,640
Average Volume 260,640
Average Volume10Days 269,080
Beta 0.817
Bid 11.91
Bid Size 2
Book Value 0.446
City Melbourne
Compensation As Of Epoch Date 1,767,139,200
Country Australia
Crypto Tradeable 0
Currency USD
Current Price 16.46
Current Ratio 1.581
Custom Price Alert Confidence HIGH
Date Short Interest 1,774,915,200
Day High 16.7859
Day Low 16.29
Debt To Equity 23.516
Earnings Call Timestamp End 1,772,143,200
Earnings Call Timestamp Start 1,772,143,200
Earnings Timestamp 1,772,139,600
Earnings Timestamp End 1,772,139,600
Earnings Timestamp Start 1,772,139,600
Ebitda -64,339,000
Ebitda Margins -0.98402
Enterprise To Ebitda -329.724
Enterprise To Revenue 324.454
Enterprise Value 21,214,124,032
Eps Current Year -0.49
Eps Forward -0.07
Eps Trailing Twelve Months -0.74
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fax 61 3 9639 6030
Fifty Day Average 15.539
Fifty Day Average Change 0.9209995
Fifty Day Average Change Percent 0.059270196
Fifty Two Week Change Percent 60.116734
Fifty Two Week High 21.5
Fifty Two Week High Change -5.040001
Fifty Two Week High Change Percent -0.23441865
Fifty Two Week Low 9.88
Fifty Two Week Low Change 6.579999
Fifty Two Week Low Change Percent 0.6659918
Fifty Two Week Range 9.88 - 21.5
Financial Currency USD
First Trade Date Milliseconds 1,263,997,800,000
Float Shares 826,414,832
Forward Eps -0.07
Forward P E -235.14284
Free Cashflow -69,438,336
Full Exchange Name NasdaqGS
Full Time Employees 81
Gmt Off Set Milliseconds -14,400,000
Gross Margins -0.35535
Gross Profits -23,234,000
Has Pre Post Market Data 1
Held Percent Insiders 0.05051
Held Percent Institutions 0.03481
Implied Shares Outstanding 130,875,969
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 0
Language en-US
Last Fiscal Year End 1,751,241,600
Last Split Date 1,704,844,800
Last Split Factor 1:2
Long Business Summary Mesoblast Limited, together with its subsidiaries, engages in the development of regenerative medicine products in Australia, the United States, Singapore, and Switzerland. The company's proprietary regenerative medicine technology platform is based on specialized cells known as mesenchymal lineage cells. It offers Remestemcel-L, which is in Phase III clinical trials for the treatment of systemic inflammatory diseases, including steroid refractory acute graft versus host disease and biologic refractory inflammatory bowel disease, as well as ulcerative colitis and Crohn's disease; and Remestemcel-L, which is in Phase III clinical trials to treat chronic heart failure and chronic low back pain due to degenerative disc disease. The company is also developing MPC-300-IV to treat biologic refractory rheumatoid arthritis diabetic nephropathy. It has strategic partnerships with Tasly Pharmaceutical Group to offer MPC-150-IM for the treatment or prevention of chronic heart failure; MPC-25-IC for the treatment or prevention of acute myocardial infarction; and Ryoncil for the treatment of pediatric SR-aGVHD; JCR Pharmaceuticals Co. Ltd. to treat wound healing in patients with epidermolysis bullosa and for the treatment of neonatal hypoxic ischemic encephalopathy; and Grünenthal to develops and commercializes cell therapy for the treatment of chronic low back pain. The company was incorporated in 2004 and is headquartered in Melbourne, Australia.
Long Name Mesoblast Limited
Market us_market
Market Cap 2,154,218,240
Market State CLOSED
Max Age 86,400
Message Board Id finmb_20356678
Most Recent Quarter 1,767,139,200
Net Income To Common -94,370,000
Next Fiscal Year End 1,782,777,600
Non Diluted Market Cap 2,075,334,034
Number Of Analyst Opinions 2
Open 16.29
Operating Cashflow -59,643,000
Operating Margins -0.55158
Payout Ratio 0.0
Phone 61 3 9639 6036
Post Market Change 0.3200016
Post Market Change Percent 1.9441167
Post Market Price 16.78
Post Market Time 1,776,460,065
Previous Close 16.09
Price Eps Current Year -33.591835
Price Hint 2
Price To Book 36.905827
Price To Sales Trailing12 Months 32.947178
Profit Margins -1.44332
Quick Ratio 1.353
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key buy
Recommendation Mean 1.66667
Region US
Regular Market Change 0.369999
Regular Market Change Percent 2.29956
Regular Market Day High 16.7859
Regular Market Day Low 16.29
Regular Market Day Range 16.29 - 16.7859
Regular Market Open 16.29
Regular Market Previous Close 16.09
Regular Market Price 16.46
Regular Market Time 1,776,456,001
Regular Market Volume 163,443
Return On Assets -0.06163
Return On Equity -0.18219
Revenue Growth 15.268
Revenue Per Share 0.51
Sand P52 Week Change 0.38150132
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 128,851,495
Shares Percent Shares Out 0.024500001
Shares Short 3,162,637
Shares Short Previous Month Date 1,772,150,400
Shares Short Prior Month 2,783,612
Short Name Mesoblast Limited
Short Percent Of Float 0.0337
Short Ratio 9.63
Source Interval 15
State VIC
Symbol MESO
Target High Price 35.0
Target Low Price 35.0
Target Mean Price 35.0
Target Median Price 35.0
Total Cash 129,975,000
Total Cash Per Share 0.101
Total Debt 135,144,000
Total Revenue 65,384,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -0.74
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 16.1061
Two Hundred Day Average Change 0.353899
Two Hundred Day Average Change Percent 0.021972978
Type Disp Equity
Volume 163,443
Website https://www.mesoblast.com
Zip 3,000