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Madrigal Pharmaceuticals, Inc. (MDGL)

Healthcare | Biotechnology | West Conshohocken, United States | NasdaqGS
531.00 USD -5.70 (-1.062%) ⇩ (July 13, 2026, 4 p.m. EDT)

Short-term:★★★⯪☆Long-term:★★★★☆Dividends:☆☆☆☆☆
Hot Take | July 11, 2026, 3:39 a.m. EDT

The long-term rating reflects a high-conviction growth story backed by exceptional revenue expansion and a fortress-like balance sheet, despite the company still operating at a loss. The nine-year price trajectory is a testament to this quality, delivering a massive cumulative gain without a recent multi-year decline. The short-term rating acknowledges the upward trend above key moving averages, yet the high beta and mixed options flow temper full conviction. While analysts maintain a strong buy stance, the high valuation and ongoing cash burn require careful monitoring of clinical milestones to sustain the premium.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoARIMA ✓0.031022
AutoETS0.031022
MSTL0.034719
AutoTheta0.074498

Forecast horizon: 45 days | Selected: AutoARIMA

Forecast Reliability
Score 43%
H-stat 2.33
Ljung-Box p 0.000
Jarque-Bera p 0.085
Excess Kurtosis 0.27
Attribute Value
Sector Healthcare
Debt to Equity Ratio 63.908
Revenue per Share 49.953
Market Cap 12,242,555,904
Forward P/E 42.89
Beta -1.06
Profit Margins -27.32%
Website https://www.madrigalpharma.com

As of July 11, 2026, 3:39 a.m. EDT: Speculators are positioning for volatility with heavy out-of-the-money call interest near term, suggesting a bullish bias, though significant put volume indicates hedging against downside risk. Longer-dated calls show more in-the-money positioning, hinting at sustained upside expectations.


Info Dump

Attribute Value
52 Week Change 0.70662725
Address1 Four Tower Bridge
Address2 200 Barr Harbor Drive Suite 200
All Time High 615.0
All Time Low 5.25
Ask 531.85
Ask Size 1
Audit Risk 2
Average Analyst Rating 1.4 - Strong Buy
Average Daily Volume10 Day 334,460
Average Daily Volume3 Month 327,785
Average Volume 327,785
Average Volume10Days 334,460
Beta -1.056
Bid 526.22
Bid Size 1
Board Risk 3
Book Value 23.585
City West Conshohocken
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 5
Country United States
Crypto Tradeable 0
Currency USD
Current Price 531.0
Current Ratio 3.495
Custom Price Alert Confidence HIGH
Date Short Interest 1,782,777,600
Day High 539.065
Day Low 526.14
Debt To Equity 63.908
Display Name Madrigal Pharmaceuticals
Dividend Date 1,469,404,800
Earnings Call Timestamp End 1,778,068,800
Earnings Call Timestamp Start 1,778,068,800
Earnings Timestamp 1,778,070,600
Earnings Timestamp End 1,785,933,000
Earnings Timestamp Start 1,785,933,000
Ebitda -311,996,000
Ebitda Margins -0.2755
Enterprise To Ebitda -37.748
Enterprise To Revenue 10.399
Enterprise Value 11,777,094,656
Eps Current Year -6.52333
Eps Forward 12.38
Eps Trailing Twelve Months -13.34
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 511.7298
Fifty Day Average Change 19.270203
Fifty Day Average Change Percent 0.03765699
Fifty Two Week Change Percent 70.66273
Fifty Two Week High 615.0
Fifty Two Week High Change -84.0
Fifty Two Week High Change Percent -0.13658537
Fifty Two Week Low 286.44
Fifty Two Week Low Change 244.56
Fifty Two Week Low Change Percent 0.85379136
Fifty Two Week Range 286.44 - 615.0
Financial Currency USD
First Trade Date Milliseconds 1,170,772,200,000
Float Shares 13,995,016
Forward Eps 12.38
Forward P E 42.89176
Free Cashflow -156,403,504
Full Exchange Name NasdaqGS
Full Time Employees 915
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,782,864,000
Gross Margins 0.9307
Gross Profits 1,054,008,000
Has Pre Post Market Data 1
Held Percent Insiders 0.056799997
Held Percent Institutions 1.0699099
Implied Shares Outstanding 23,055,659
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Ir Website http://ir.syntapharma.com/phoenix.zhtml?c=147988&p=irol-irhome
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Last Split Date 1,469,404,800
Last Split Factor 1:35
Long Business Summary Madrigal Pharmaceuticals, Inc., a biopharmaceutical company, focuses on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH) in the United States. It offers Rezdiffra, a liver-directed thyroid hormone receptor beta agonist for treating MASH. The company was founded in 2016 and is headquartered in West Conshohocken, Pennsylvania.
Long Name Madrigal Pharmaceuticals, Inc.
Market us_market
Market Cap 12,242,555,904
Market State PRE
Max Age 86,400
Message Board Id finmb_144939852
Most Recent Quarter 1,774,915,200
Net Income To Common -309,436,992
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 12,252,699,418
Number Of Analyst Opinions 14
Open 534.05
Operating Cashflow -268,096,992
Operating Margins -0.29782
Overall Risk 5
Payout Ratio 0.0
Phone 267 824 2827
Previous Close 536.7
Price Eps Current Year -81.40014
Price Hint 2
Price To Book 22.51431
Price To Sales Trailing12 Months 10.8103
Profit Margins -0.27324
Quick Ratio 2.957
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.4
Region US
Regular Market Change -5.70001
Regular Market Change Percent -1.06205
Regular Market Day High 539.065
Regular Market Day Low 526.14
Regular Market Day Range 526.14 - 539.065
Regular Market Open 534.05
Regular Market Previous Close 536.7
Regular Market Price 531.0
Regular Market Time 1,783,972,801
Regular Market Volume 287,877
Return On Assets -0.17621
Return On Equity -0.49348
Revenue Growth 1.268
Revenue Per Share 49.953
Sand P52 Week Change 0.20365608
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 8
Shares Outstanding 23,055,659
Shares Percent Shares Out 0.153
Shares Short 3,526,539
Shares Short Previous Month Date 1,780,012,800
Shares Short Prior Month 3,823,127
Short Name Madrigal Pharmaceuticals, Inc.
Short Percent Of Float 0.17989999
Short Ratio 8.54
Source Interval 15
State PA
Symbol MDGL
Target High Price 964.0
Target Low Price 542.0
Target Mean Price 678.7143
Target Median Price 649.5
Total Cash 812,771,008
Total Cash Per Share 35.253
Total Debt 347,311,008
Total Revenue 1,132,489,984
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -13.34
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 500.38364
Two Hundred Day Average Change 30.616364
Two Hundred Day Average Change Percent 0.06118578
Type Disp Equity
Volume 287,877
Website https://www.madrigalpharma.com
Zip 19,428