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MBX Biosciences, Inc. (MBX)

Healthcare | Biotechnology | Carmel, United States | NasdaqGS
33.77 USD +0.55 (1.656%) ⇧ (April 17, 2026, 4 p.m. EDT)
After hours: 33.77

Short-term: ★★★☆☆ | Long-term: ★☆☆☆☆ | Dividends: ★★☆☆☆
Hot Take | April 19, 2026, 12:54 a.m. EDT

Despite a 'Strong Buy' analyst consensus and solid cash reserves, MBX faces a severe short-term headwind due to massive speculative put flow targeting a drop below $25–27. The market is clearly pricing in a correction for the recent rally. Fundamentally, the high short ratio (6.83x) and negative consensus EPS suggest the stock is in a fragile 'catch-a-fall' phase. While the long-term thesis on the obesity program is intact, the current technicals and options flow signal a sell-off before stability returns, making this a risky hold at current levels.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoARIMA ✓0.117897
AutoETS0.124604
MSTL0.131453
AutoTheta0.137724

Forecast horizon: 45 days | Selected: AutoARIMA

Forecast Reliability
Score 48%
H-stat 4.84
Ljung-Box p 0.000
Jarque-Bera p 0.217
Excess Kurtosis -1.26
Attribute Value
Sector Healthcare
Debt to Equity Ratio 0.161
Market Cap 1,604,420,992
Forward P/E -8.31
Website https://mbxbio.com

As of April 19, 2026, 12:54 a.m. EDT: Derivatives data reveals a distinct short-term hedging stance. In the Apr 17 expiration, put volume and OI massively outweigh calls (930 vs 65 vol), with heavy positioning at OTM strikes of 22.5 and 25, despite the stock sitting at 33.77. However, call OI is surprisingly concentrated at the 30 strike (OTM relative to current price, yet deep ITM compared to 52-week lows) indicating a defensive 'floor' play or volatility hedge rather than a directional pump. The April 17 ATM IV is elevated relative to the spread with further DTE, suggesting traders are pricing in a Auflösung of the current rally at the month-end. Longer-dated strikes show higher OI far below current price (e.g., 7.50 calls, 25 puts), indicating a 'range-bound' or 'double dip' positioning rather than an aggressive breakout trade.


Info Dump

Attribute Value
52 Week Change 3.420157
Address1 11,711 North Meridian Street
Address2 Suite 300
All Time High 44.89
All Time Low 4.807
Ask 43.18
Ask Size 2
Audit Risk 8
Average Analyst Rating 1.5 - Strong Buy
Average Daily Volume10 Day 447,150
Average Daily Volume3 Month 574,535
Average Volume 574,535
Average Volume10Days 447,150
Bid 24.99
Bid Size 2
Board Risk 6
Book Value 8.218
City Carmel
Compensation As Of Epoch Date 1,735,603,200
Compensation Risk 9
Country United States
Crypto Tradeable 0
Currency USD
Current Price 33.77
Current Ratio 24.623
Custom Price Alert Confidence HIGH
Date Short Interest 1,774,915,200
Day High 35.0
Day Low 33.31
Debt To Equity 0.161
Display Name MBX Biosciences
Earnings Call Timestamp End 1,754,564,400
Earnings Call Timestamp Start 1,754,564,400
Earnings Timestamp 1,773,318,600
Earnings Timestamp End 1,778,502,600
Earnings Timestamp Start 1,778,502,600
Ebitda -97,807,000
Ebitda Margins 0.0
Enterprise To Ebitda -12.589
Enterprise Value 1,231,311,872
Eps Current Year -2.89169
Eps Forward -4.0616
Eps Trailing Twelve Months -2.38
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 32.3661
Fifty Day Average Change 1.4039001
Fifty Day Average Change Percent 0.043375634
Fifty Two Week Change Percent 342.0157
Fifty Two Week High 44.89
Fifty Two Week High Change -11.119999
Fifty Two Week High Change Percent -0.24771662
Fifty Two Week Low 7.2
Fifty Two Week Low Change 26.57
Fifty Two Week Low Change Percent 3.6902778
Fifty Two Week Range 7.2 - 44.89
Financial Currency USD
First Trade Date Milliseconds 1,726,234,200,000
Float Shares 29,029,709
Forward Eps -4.0616
Forward P E -8.314457
Free Cashflow -52,442,376
Full Exchange Name NasdaqGS
Full Time Employees 63
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,775,001,600
Gross Margins 0.0
Has Pre Post Market Data 1
Held Percent Insiders 0.02743
Held Percent Institutions 1.02553
Implied Shares Outstanding 47,510,243
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Ipo Expected Date 2,024-09-13
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary MBX Biosciences, Inc., a clinical-stage biopharmaceutical company, focuses on the discovery and development of precision peptide therapies for the treatment of endocrine and metabolic disorders. Its lead product candidate is Canvuparatide (MBX 2109), a parathyroid hormone peptide prodrug, which is in Phase 3 clinical trial for the treatment of chronic hypoparathyroidism. The company is also developing Imapextide (MBX 1416), a long-acting glucagon-like peptide-1 (GLP-1) receptor antagonist that is in Phase 2 clinical trial a potential therapy for post-bariatric hypoglycemia, a chronic complication of bariatric surgery. In addition, it is developing MBX 4291, a lead obesity product candidate, which is in investigational new drug-enabling studies for the treatment of obesity and co-morbidities. The company was founded in 2018 and is based in Carmel, Indiana.
Long Name MBX Biosciences, Inc.
Market us_market
Market Cap 1,604,420,992
Market State CLOSED
Max Age 86,400
Message Board Id finmb_613097171
Most Recent Quarter 1,767,139,200
Net Income To Common -86,971,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 1,601,570,291
Number Of Analyst Opinions 11
Open 34.6601
Operating Cashflow -79,949,000
Operating Margins 0.0
Overall Risk 8
Payout Ratio 0.0
Phone 317 659 0200
Post Market Change 0.0
Post Market Change Percent 0.0
Post Market Price 33.77
Post Market Time 1,776,456,605
Previous Close 33.22
Price Eps Current Year -11.678292
Price Hint 2
Price To Book 4.109272
Profit Margins 0.0
Quick Ratio 24.255
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.5
Region US
Regular Market Change 0.549999
Regular Market Change Percent 1.65563
Regular Market Day High 35.0
Regular Market Day Low 33.31
Regular Market Day Range 33.31 - 35.0
Regular Market Open 34.6601
Regular Market Previous Close 33.22
Regular Market Price 33.77
Regular Market Time 1,776,456,001
Regular Market Volume 302,557
Return On Assets -0.18751
Return On Equity -0.27757
Sand P52 Week Change 0.38150132
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 8
Shares Outstanding 47,510,243
Shares Percent Shares Out 0.0756
Shares Short 3,593,407
Shares Short Previous Month Date 1,772,150,400
Shares Short Prior Month 2,395,339
Short Name MBX Biosciences, Inc.
Short Percent Of Float 0.117
Short Ratio 6.83
Source Interval 15
State IN
Symbol MBX
Target High Price 88.0
Target Low Price 20.0
Target Mean Price 62.54545
Target Median Price 66.0
Total Cash 373,704,992
Total Cash Per Share 7.866
Total Debt 596,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -2.38
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 24.29655
Two Hundred Day Average Change 9.47345
Two Hundred Day Average Change Percent 0.38990924
Type Disp Equity
Volume 302,557
Website https://mbxbio.com
Zip 46,032