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Lexicon Pharmaceuticals, Inc. (LXRX)

Healthcare | Biotechnology | The Woodlands, United States | NasdaqCM
1.87 USD +0.03 (1.630%) ⇧ (April 17, 2026, 4 p.m. EDT)
After hours: 1.89 +0.02 (1.070%) ⇧ (April 17, 2026, 7:54 p.m. EDT)

Short-term: ★★☆☆☆ | Long-term: ★☆☆☆☆ | Dividends: ☆☆☆☆☆
Hot Take | April 11, 2026, 1:38 p.m. EDT

LXRX is a highly volatile stock with a recent price range between $0.48 and $1.84, showing a potential rebound after recent dips. The stock has seen positive news, including partnership milestones and insider buying, which could drive momentum. However, the company is currently unprofitable, with negative profit margins and a high debt-to-equity ratio, indicating financial risk. While there is potential for short-term gains, the lack of consistent dividends and the company's financial instability make it a speculative play rather than a safe investment. Investors should monitor earnings reports and partnership developments closely.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
MSTL ✓0.160578
AutoARIMA0.166123
AutoETS0.166124
AutoTheta0.167360

Forecast horizon: 45 days | Selected: MSTL

Forecast Reliability
Score 55%
H-stat 2.60
Ljung-Box p 0.000
Jarque-Bera p 0.067
Excess Kurtosis -0.33
Attribute Value
Sector Healthcare
Debt to Equity Ratio 57.874
Revenue per Share 0.137
Market Cap 792,282,752
Forward P/E -8.99
Beta 0.95
Profit Margins -101.08%
Website https://www.lexpharma.com

As of April 11, 2026, 1:38 p.m. EDT: Options activity indicates mixed sentiment. Calls show a concentration of interest around the 1.5 strike, suggesting support, while puts have limited activity, with a focus on the 1.0 strike. The high IV on some strikes suggests volatility, and the presence of top OI at higher strikes (e.g., 2.0) may indicate a potential upside bias. However, the lack of significant put activity suggests limited downside concern. Overall, the options data implies a cautious outlook with potential for upward movement but not a strong consensus.


Info Dump

Attribute Value
52 Week Change 2.2280703
Address1 2,445 Technology Forest Boulevard
Address2 11th Floor
All Time High 344.75
All Time Low 0.28
Ask 2.15
Ask Size 1
Average Analyst Rating 2.0 - Buy
Average Daily Volume10 Day 1,961,200
Average Daily Volume3 Month 2,997,178
Average Volume 2,997,178
Average Volume10Days 1,961,200
Beta 0.946
Bid 1.88
Bid Size 1
Book Value 0.296
City The Woodlands
Compensation As Of Epoch Date 1,767,139,200
Country United States
Crypto Tradeable 0
Currency USD
Current Price 1.87
Current Ratio 4.883
Custom Price Alert Confidence HIGH
Date Short Interest 1,774,915,200
Day High 1.95
Day Low 1.855
Debt To Equity 57.874
Display Name Lexicon Pharmaceuticals
Earnings Call Timestamp End 1,772,717,400
Earnings Call Timestamp Start 1,772,717,400
Earnings Timestamp 1,772,717,400
Earnings Timestamp End 1,778,589,000
Earnings Timestamp Start 1,778,589,000
Ebitda -48,290,000
Ebitda Margins -0.96962
Enterprise To Ebitda -15.703
Enterprise To Revenue 15.226
Enterprise Value 758,289,728
Eps Current Year -0.18108
Eps Forward -0.20805
Eps Trailing Twelve Months -0.14
Esg Populated 0
Exchange NCM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fax 281 863 8088
Fifty Day Average 1.5596
Fifty Day Average Change 0.3104
Fifty Day Average Change Percent 0.19902539
Fifty Two Week Change Percent 222.80702
Fifty Two Week High 1.95
Fifty Two Week High Change -0.08000004
Fifty Two Week High Change Percent -0.04102566
Fifty Two Week Low 0.49
Fifty Two Week Low Change 1.38
Fifty Two Week Low Change Percent 2.8163264
Fifty Two Week Range 0.49 - 1.95
Financial Currency USD
First Trade Date Milliseconds 955,114,200,000
Float Shares 417,795,687
Forward Eps -0.20805
Forward P E -8.988224
Free Cashflow -47,815,248
Full Exchange Name NasdaqCM
Full Time Employees 81
Gmt Off Set Milliseconds -14,400,000
Gross Margins 0.86822
Gross Profits 43,240,000
Has Pre Post Market Data 1
Held Percent Insiders 0.0102699995
Held Percent Institutions 0.68512
Implied Shares Outstanding 423,680,612
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Ir Website http://www.lexpharma.com/investors/index.html
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Last Split Date 1,432,166,400
Last Split Factor 1:7
Long Business Summary Lexicon Pharmaceuticals, Inc., a biopharmaceutical company, focuses on the discovery, development, and commercialization of pharmaceutical products for the treatment of human disease. The company develops sotagliflozin, an orally-delivered small molecule drug for the treatment of hypertrophic cardiomyopathy, and ZYNQUISTA (sotagliflozin) for the treatment of type 1 diabetes. It also commercializes INPEFA (sotagliflozin), a once-daily oral tablet to reduce the risk of cardiovascular death, hospitalization for heart failure, and urgent heart failure visit in adults with heart failure or type 2 diabetes, CKD, and other cardiovascular risk factors. In addition, the company develops LX9851, an orally-delivered small molecule drug candidate for the treatment of obesity and associated cardiometabolic disorders, and pilavapadin (LX9211), an orally-delivered small molecule drug candidate for the treatment of neuropathic pain. It has strategic collaboration and license agreements with Viatris Inc. and Bristol-Myers Squibb Company. The company was incorporated in 1995 and is headquartered in The Woodlands, Texas.
Long Name Lexicon Pharmaceuticals, Inc.
Market us_market
Market Cap 792,282,752
Market State CLOSED
Max Age 86,400
Message Board Id finmb_30781
Most Recent Quarter 1,767,139,200
Net Income To Common -50,341,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 777,453,921
Number Of Analyst Opinions 5
Open 1.86
Operating Cashflow -67,851,000
Operating Margins -2.6907
Payout Ratio 0.0
Peg Ratio -13.77
Phone 281 863 3000
Post Market Change 0.01999998
Post Market Change Percent 1.0695177
Post Market Price 1.89
Post Market Time 1,776,470,044
Previous Close 1.84
Price Eps Current Year -10.326927
Price Hint 4
Price To Book 6.3175673
Price To Sales Trailing12 Months 15.908334
Profit Margins -1.0108
Quick Ratio 4.726
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key buy
Recommendation Mean 2.0
Region US
Regular Market Change 0.03
Regular Market Change Percent 1.63043
Regular Market Day High 1.95
Regular Market Day Low 1.855
Regular Market Day Range 1.855 - 1.95
Regular Market Open 1.86
Regular Market Previous Close 1.84
Regular Market Price 1.87
Regular Market Time 1,776,456,001
Regular Market Volume 3,132,866
Return On Assets -0.12647
Return On Equity -0.39719
Revenue Growth -0.793
Revenue Per Share 0.137
Sand P52 Week Change 0.36506534
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 423,680,611
Shares Percent Shares Out 0.0541
Shares Short 22,932,295
Shares Short Previous Month Date 1,772,150,400
Shares Short Prior Month 23,139,559
Short Name Lexicon Pharmaceuticals, Inc.
Short Percent Of Float 0.1067
Short Ratio 8.56
Source Interval 15
State TX
Symbol LXRX
Target High Price 6.0
Target Low Price 1.0
Target Mean Price 3.36
Target Median Price 2.3
Total Cash 96,230,000
Total Cash Per Share 0.227
Total Debt 62,237,000
Total Revenue 49,803,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -0.14
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 1.33985
Two Hundred Day Average Change 0.53015006
Two Hundred Day Average Change Percent 0.39567867
Type Disp Equity
Volume 3,132,866
Website https://www.lexpharma.com
Zip 77,381