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Lipocine Inc. (LPCN)

Healthcare | Biotechnology | Salt Lake City, United States | NasdaqCM
2.17 USD -0.06 (-2.691%) ⇩ (Aug. 28, 2026, 4 p.m. EDT)
After hours: 2.13 -0.04 (-0.040%) ⇩ (Aug. 28, 2026, 4:48 p.m. EDT)

Short-term:★☆☆☆☆Long-term:⯪☆☆☆☆Dividends:☆☆☆☆☆
Hot Take | Aug. 22, 2026, 2:25 a.m. EDT

The investment case for this biotech stock has collapsed due to a catastrophic multi-year decline and deteriorating fundamentals. The price has lost 95% of its value over the last nine years, with six consecutive years of negative annual returns, signaling a deep structural failure rather than a temporary setback. This trajectory is compounded by shrinking revenues, which fell nearly 70% year-over-year, alongside severe losses in profitability with negative operating margins and equity returns. The balance sheet, while currently showing low debt relative to cash, cannot mask the reality that the core business is failing to generate value or grow. Recent news confirms this distress, citing a failed Phase 3 trial that triggered a massive stock drop and forced a strategic reevaluation. With no dividend history to provide income and a forward P/E indicating negative earnings, there is no margin of safety here; the market has already priced in the business model's inability to sustain itself. The recent price action shows a flat, depressed range near the lows, offering no immediate technical relief.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoETS ✓0.056703
AutoARIMA0.056703
MSTL0.060719
AutoTheta0.356130

Forecast horizon: 45 days | Selected: AutoETS

Forecast Reliability
Score 36%
H-stat 0.80
Ljung-Box p 0.000
Jarque-Bera p 0.378
Excess Kurtosis -1.01
Attribute Value
Sector Healthcare
Debt to Equity Ratio 1.184
Revenue per Share 0.24
Market Cap 17,890,030
Forward P/E -1.75
Beta 0.46
Website https://www.lipocine.com

Info Dump

Attribute Value
52 Week Change -0.23103446
Address1 675 Arapeen Drive
Address2 Suite 202
All Time High 326.91
All Time Low 1.81
Ask 2.76
Ask Size 2
Average Daily Volume10 Day 35,510
Average Daily Volume3 Month 62,875
Average Volume 62,875
Average Volume10Days 35,510
Beta 0.46
Bid 1.6
Bid Size 2
Book Value 2.64
City Salt Lake City
Compensation As Of Epoch Date 1,767,139,200
Country United States
Crypto Tradeable 0
Currency USD
Current Price 2.17
Current Ratio 11.478
Custom Price Alert Confidence HIGH
Date Short Interest 1,786,665,600
Day High 2.215
Day Low 2.13
Debt To Equity 1.184
Display Name Lipocine
Earnings Timestamp End 1,755,174,600
Earnings Timestamp Start 1,755,174,600
Ebitda -12,509,986
Ebitda Margins 0.0
Enterprise To Ebitda 0.409
Enterprise To Revenue -3.261
Enterprise Value -5,118,773
Eps Forward -1.24
Eps Trailing Twelve Months -1.85
Esg Populated 0
Exchange NCM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fax 801 994 7388
Fifty Day Average 2.2384
Fifty Day Average Change -0.068399906
Fifty Day Average Change Percent -0.0305575
Fifty Two Week Change Percent -23.103445
Fifty Two Week High 12.37
Fifty Two Week High Change -10.2
Fifty Two Week High Change Percent -0.8245756
Fifty Two Week Low 1.81
Fifty Two Week Low Change 0.36000013
Fifty Two Week Low Change Percent 0.19889511
Fifty Two Week Range 1.81 - 12.37
Financial Currency USD
First Trade Date Milliseconds 1,382,448,600,000
Float Shares 6,552,450
Forward Eps -1.24
Forward P E -1.75
Free Cashflow -6,939,857
Full Exchange Name NasdaqCM
Full Time Employees 14
Fullday Change -0.0599999
Fullday Change Percent -2.69058
Fullday Price 2.13
Gmt Off Set Milliseconds -14,400,000
Gross Margins 1.0
Gross Profits 1,569,460
Has Pre Post Market Data 1
Held Percent Insiders 0.04507
Held Percent Institutions 0.36188
Implied Shares Outstanding 8,244,253
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Last Split Date 1,683,849,600
Last Split Factor 1:17
Long Business Summary Lipocine Inc., a clinical-stage biopharmaceutical company, engages in the research and development for the delivery of drugs using its proprietary delivery technology. The company offers TLANDO, an oral testosterone replacement therapy (TRT) comprising testosterone undecanoate. It also develops LPCN 1154 (BRLIZIO), an oral neuro-steroid in a Phase 3 pivotal trial for postpartum depression; LPCN 1148, a prodrug of testosterone and testosterone laurate that has completed a Phase 2 trial for the management of decompensated cirrhosis; LPCN 1107, an oral hydroxy progesterone caproate product that has completed a Phase 2 trial for the prevention of recurrent preterm birth; LPCN 1144, an oral prodrug of bioidentical testosterone that has completed a Phase 2 trial for pre-cirrhotic non-alcoholic steatohepatitis; and LPCN 2401, an oral formulation comprising a proprietary anabolic androgen receptor agonist that is in a Phase 2 trial to manage incretin mimetic use in obesity management. In addition, the company is developing LPCN 2201, an oral brexanolone formulation that has completed a Phase 1 trial for major depressive disorders; LPCN 2203, an oral candidate that has completed a Phase 1 trial for management of essential tremor; and LPCN 2101, a neuroactive steroids (NAS) candidate that has completed a Phase 1 trial for drug-resistant epilepsy and women with epilepsy. The company's products focus on neurological and psychiatric central nervous system (CNS) disorders, liver disease, and hormone supplementation in the United States. It has a collaboration with Verity Pharmaceuticals, Inc. to develop and commercialize TLANDO; and TLANDO XR (LPCN 1111), a once-daily oral product candidate that has completed a Phase 2 trial for testosterone replacement therapy. Lipocine Inc. was founded in 1997 and is headquartered in Salt Lake City, Utah.
Long Name Lipocine Inc.
Market us_market
Market Cap 17,890,030
Market State CLOSED
Max Age 86,400
Message Board Id finmb_8057882
Most Recent Quarter 1,782,777,600
Net Income To Common -11,851,405
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 18,384,684
Number Of Analyst Opinions 1
Open 2.2039
Operating Cashflow -11,190,794
Operating Margins -14.9514
Payout Ratio 0.0
Phone 801 994 7383
Post Market Change -0.03999996
Post Market Change Percent -1.8433162
Post Market Price 2.13
Post Market Time 1,787,950,109
Previous Close 2.23
Price Hint 4
Price To Book 0.8219697
Price To Sales Trailing12 Months 11.398844
Profit Margins 0.0
Quick Ratio 11.392
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key none
Region US
Regular Market Change -0.0599999
Regular Market Change Percent -2.69058
Regular Market Day High 2.215
Regular Market Day Low 2.13
Regular Market Day Range 2.13 - 2.215
Regular Market Open 2.2039
Regular Market Previous Close 2.23
Regular Market Price 2.17
Regular Market Time 1,787,947,201
Regular Market Volume 19,546
Return On Assets -0.37043
Return On Equity -0.60939
Revenue Growth -0.695
Revenue Per Share 0.24
Sand P52 Week Change 0.20504117
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 8,244,253
Shares Percent Shares Out 0.0115
Shares Short 94,427
Shares Short Previous Month Date 1,784,073,600
Shares Short Prior Month 123,024
Short Name Lipocine Inc.
Short Percent Of Float 0.0117
Short Ratio 2.42
Source Interval 15
State UT
Symbol LPCN
Target High Price 6.0
Target Low Price 6.0
Target Mean Price 6.0
Target Median Price 6.0
Total Cash 23,266,608
Total Cash Per Share 2.822
Total Debt 257,807
Total Revenue 1,569,460
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -1.85
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 4.52125
Two Hundred Day Average Change -2.3512497
Two Hundred Day Average Change Percent -0.5200442
Type Disp Equity
Volume 19,546
Website https://www.lipocine.com
Zip 84,108