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Lakefront Biotherapeutics NV (LKFT)

Healthcare | Biotechnology | Mechelen, Belgium | NasdaqGS
29.08 USD +0.03 (0.103%) ⇧ (Oct. 14, 2026, 12:18 p.m. EDT)

Short-term:★★⯪☆☆Long-term:★★⯪☆☆Dividends:☆☆☆☆☆
Hot Take ↕ | Oct. 10, 2026, 6:22 a.m. EDT

The investment case for Lakefront Biotherapeutics is defined by a stark contradiction between its pristine balance sheet and its deteriorating operational reality. Fundamentally, the company holds a fortress-like liquidity position with nearly $2.2 billion in cash against negligible debt, resulting in a massive current ratio of 32.8x. This financial strength is undeniable. However, this safety net is propping up a business that is actively shrinking; revenue has plummeted by 81.5% year-over-year, and operating margins are deeply negative. While the stock recently posted a positive annual return, the underlying trajectory is one of severe contraction, suggesting the market is pricing in a fundamental shift in the company's ability to generate sales. The short-term outlook remains neutral-to-slightly-bearish despite the cash pile. The massive short interest (over 8% of float) combined with a short ratio of 13 suggests intense skepticism among leveraged investors, which could fuel volatility but also indicates a lack of genuine buying conviction. The recent news of share repurchases is a positive signal of management confidence, yet it cannot fully offset the alarming trend of collapsing revenues. There is no dividend yield to provide income, making this purely a capital appreciation play on a shrinking business. The options market tells a different story than the fundamentals, with speculators aggressively betting on a bounce or recovery, likely driven by the hope that the cash reserves will fund a turnaround or a strategic acquisition. However, relying on a 'cash-rich' narrative to reverse an 80% revenue drop is a high-risk strategy. Until the revenue decline stabilizes or reverses, the long-term thesis remains fragile, despite the attractive valuation multiples which may simply reflect the market's fear of permanent impairment.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoTheta ✓0.035015
AutoETS0.035040
AutoARIMA0.035040
MSTL0.035201

Forecast horizon: 45 days | Selected: AutoTheta

Forecast Reliability
Score 47%
H-stat 2.56
Ljung-Box p 0.000
Jarque-Bera p 0.629
Excess Kurtosis -0.70
Attribute Value
Sector Healthcare
Debt to Equity Ratio 0.195
Revenue per Share 0.7517
Market Cap 1,904,294,272
Trailing P/E 2.76
Forward P/E -24.58
Beta 0.06
Profit Margins 60.23%
Previous Name Galapagos NV
Website https://lakefrontbio.com

As of Oct. 10, 2026, 6:22 a.m. EDT: Options activity shows a distinct bullish skew with heavy open interest in out-of-the-money calls (OTM OI % consistently above 80%) compared to puts. Speculators are positioning for upside moves, evidenced by significant call volume at strikes like $32.50 and $35.00 across multiple expirations. Conversely, put activity is sparse, with minimal open interest in protective strikes below the current price, indicating a lack of hedging demand and a speculative bias toward appreciation.


Info Dump

Attribute Value
52 Week Change -0.14659226
Address1 SchaliEnhoevedreef 20 T
All Time High 274.03
All Time Low 12.91
Ask 36.91
Ask Size 2
Average Daily Volume10 Day 316,800
Average Daily Volume3 Month 275,575
Average Volume 275,575
Average Volume10Days 316,800
Beta 0.058
Bid 20.61
Bid Size 2
Book Value 2.7736876
City Mechelen
Compensation As Of Epoch Date 1,767,139,200
Country Belgium
Crypto Tradeable 0
Currency USD
Current Price 29.08
Current Ratio 32.839
Custom Price Alert Confidence HIGH
Date Short Interest 1,790,726,400
Day High 29.235
Day Low 28.5
Debt To Equity 0.195
Display Name Lakefront Biotherapeutics
Dividend Yield 0.0
Earnings Timestamp 1,794,427,200
Earnings Timestamp End 1,794,427,200
Earnings Timestamp Start 1,794,427,200
Ebitda 568,918,016
Ebitda Margins 0.57433
Enterprise To Ebitda 63.124
Enterprise To Revenue 36.254
Enterprise Value 35,912,466,432
Eps Current Year -0.71
Eps Forward -1.1829282
Eps Trailing Twelve Months 10.52
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 15
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fax 32 1 534 29 01
Fifty Day Average 28.576
Fifty Day Average Change 0.5039997
Fifty Day Average Change Percent 0.017637167
Fifty Two Week Change Percent -14.659225
Fifty Two Week High 36.24
Fifty Two Week High Change -7.1600018
Fifty Two Week High Change Percent -0.19757178
Fifty Two Week Low 25.68
Fifty Two Week Low Change 3.3999996
Fifty Two Week Low Change Percent 0.13239874
Fifty Two Week Range 25.68 - 36.24
Financial Currency EUR
First Trade Date Milliseconds 1,330,353,000,000
Float Shares 474,384,844
Forward Eps -1.1829282
Forward P E -24.583065
Free Cashflow 138,206,256
Full Exchange Name NasdaqGS
Full Time Employees 196
Fullday Change 0.030000687
Fullday Change Percent 0.10327259
Fullday Price 29.08
Gmt Off Set Milliseconds -14,400,000
Gross Margins 0.67612
Gross Profits 669,748,992
Has Pre Post Market Data 1
Held Percent Insiders 0.25447
Held Percent Institutions 0.23629
Implied Shares Outstanding 65,484,670
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 0
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Lakefront Biotherapeutics NV, a biotechnology company, develops medicines focusing on oncology and immunology primarily in the United States and Europe. The company's pipeline products comprise GLPG3667, which is in a phase 2 clinical trial in dermatomyositis and systemic lupus erythematosus; GLPG5101, a CD19 CAR-T product candidate manufactured at point-of-care, currently in a phase 1/2 trial in relapsed/refractory non-hodgkin lymphoma; and GLPG5301, a BCMA CAR-T product candidate manufactured at point-of-care, currently in phase 1/2 in relapsed/refractory multiple myeloma. The company has collaboration agreements with Gilead Sciences, Inc. The company was formerly known as Galapagos NV and changed its name to Lakefront Biotherapeutics NV in May 2026. The company was incorporated in 1999 and is headquartered in Mechelen, Belgium.
Long Name Lakefront Biotherapeutics NV
Market us_market
Market Cap 1,904,294,272
Market State REGULAR
Max Age 86,400
Message Board Id finmb_1716658
Most Recent Quarter 1,782,777,600
Name Change Date 2,026-10-14
Net Income To Common 594,324,992
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 1,978,905,935
Number Of Analyst Opinions 3
Open 28.675
Operating Cashflow -226,908,992
Operating Margins -3.5929801
Payout Ratio 0.0
Phone 32 1 534 29 00
Prev Name Galapagos NV
Previous Close 29.05
Price Eps Current Year -40.95775
Price Hint 2
Price To Book 10.484238
Price To Sales Trailing12 Months 1.9224149
Profit Margins 0.60231
Quick Ratio 32.647
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key none
Region US
Regular Market Change 0.030000687
Regular Market Change Percent 0.10327259
Regular Market Day High 29.235
Regular Market Day Low 28.5
Regular Market Day Range 28.5 - 29.235
Regular Market Open 28.675
Regular Market Previous Close 29.05
Regular Market Price 29.08
Regular Market Time 1,791,994,714
Regular Market Volume 70,335
Return On Assets 0.09929
Return On Equity 0.20121
Revenue Growth -0.815
Revenue Per Share 0.7517
Sand P52 Week Change 0.17004645
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 65,484,670
Shares Percent Shares Out 0.0507
Shares Short 3,317,951
Shares Short Previous Month Date 1,788,134,400
Shares Short Prior Month 3,295,220
Short Name Lakefront Biotherapeutics
Short Percent Of Float 0.0828
Short Ratio 10.63
Source Interval 15
Symbol LKFT
Target High Price 43.72957
Target Low Price 21.127544
Target Mean Price 29.961826
Target Median Price 25.028357
Total Cash 2,239,548,928
Total Cash Per Share 1.706
Total Debt 6,362,000
Total Revenue 990,574,016
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps 10.52
Trailing P E 2.7642584
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 30.04935
Two Hundred Day Average Change -0.9693508
Two Hundred Day Average Change Percent -0.032258626
Type Disp Equity
Volume 70,335
Website https://lakefrontbio.com
Zip 2,800