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Lakefront Biotherapeutics NV (LKFT)

Healthcare | Biotechnology | Mechelen, Belgium | NasdaqGS
28.88 USD -0.56 (-1.902%) ⇩ (Aug. 28, 2026, 4 p.m. EDT)
After hours: 28.88

Short-term:★★⯪☆☆Long-term:★★⯪☆☆Dividends:☆☆☆☆☆
Hot Take | Aug. 22, 2026, 3:13 a.m. EDT

The investment case here is defined by a stark contradiction between pristine balance sheet metrics and deteriorating business fundamentals. On paper, the company holds a fortress-like liquidity position with nearly $2.2 billion in cash against negligible debt, resulting in a current ratio of 32.8 and a trailing P/E of just 2.7. This financial structure supports a neutral-to-positive long-term rating, as the entity is unlikely to face solvency issues despite its operational struggles. However, the operational reality tells a different story. Revenue has collapsed by 81.5% year-over-year, and operating margins are deeply negative at -3.6%. While the stock price has recovered recently (+28.57% last year), bringing the cumulative 9-year return to a manageable -41%, the underlying engine is sputtering. The massive short interest (15% of float) combined with a short ratio of 15.1 indicates significant skepticism among active traders regarding the turnaround. Short-term, the stock is hovering near its 50-day moving average, offering no clear directional edge. The options market is pricing in volatility rather than a specific breakout, which aligns with the uncertainty surrounding the company's ability to generate sustainable revenue without burning through its massive cash pile. Until the revenue decline stabilizes or reverses, the high-quality balance sheet serves as a safety net rather than a catalyst for growth.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoTheta ✓0.036813
AutoETS0.036814
AutoARIMA0.036814
MSTL0.036827

Forecast horizon: 45 days | Selected: AutoTheta

Forecast Reliability
Score 51%
H-stat 0.53
Ljung-Box p 0.000
Jarque-Bera p 0.333
Excess Kurtosis -0.73
Attribute Value
Sector Healthcare
Debt to Equity Ratio 0.195
Revenue per Share 0.7517
Market Cap 1,891,197,312
Trailing P/E 2.79
Forward P/E -20.77
Beta 0.11
Profit Margins 60.23%
Previous Name Galapagos NV
Website https://lakefrontbio.com

As of Aug. 22, 2026, 3:13 a.m. EDT: Speculators are positioning for a range-bound outcome with a slight bullish bias. Call open interest significantly outweighs put open interest (roughly 2-to-1), suggesting bets on upside continuation rather than a crash. However, implied volatility is elevated (66-74%), indicating fear of a sharp move in either direction. The concentration of call open interest at strikes above the current price (30, 32.5) suggests a 'long gamma' setup where traders expect the stock to stay above current levels, while the heavy put open interest at lower strikes acts as a floor.


Info Dump

Attribute Value
52 Week Change -0.07317072
Address1 SchaliEnhoevedreef 20 T
All Time High 274.03
All Time Low 12.91
Ask 37.12
Ask Size 2
Average Analyst Rating 3.0 - Hold
Average Daily Volume10 Day 250,870
Average Daily Volume3 Month 209,339
Average Volume 209,339
Average Volume10Days 250,870
Beta 0.112
Bid 28.8
Bid Size 1
Book Value 2.8575108
City Mechelen
Country Belgium
Crypto Tradeable 0
Currency USD
Current Price 28.88
Current Ratio 32.839
Custom Price Alert Confidence HIGH
Date Short Interest 1,786,665,600
Day High 29.42
Day Low 28.73
Debt To Equity 0.195
Display Name Lakefront Biotherapeutics
Earnings Timestamp 1,794,513,600
Earnings Timestamp End 1,794,513,600
Earnings Timestamp Start 1,794,513,600
Ebitda 568,918,016
Ebitda Margins 0.57433
Enterprise To Ebitda 62.732
Enterprise To Revenue 36.029
Enterprise Value 35,689,238,528
Eps Current Year -0.71
Eps Forward -1.3904681
Eps Trailing Twelve Months 10.34
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fax 32 1 534 29 01
Fifty Day Average 28.7152
Fifty Day Average Change 0.16479874
Fifty Day Average Change Percent 0.0057390765
Fifty Two Week Change Percent -7.317072
Fifty Two Week High 37.78
Fifty Two Week High Change -8.9
Fifty Two Week High Change Percent -0.23557438
Fifty Two Week Low 25.68
Fifty Two Week Low Change 3.1999989
Fifty Two Week Low Change Percent 0.12461054
Fifty Two Week Range 25.68 - 37.78
Financial Currency EUR
First Trade Date Milliseconds 1,330,353,000,000
Float Shares 474,384,844
Forward Eps -1.3904681
Forward P E -20.769983
Free Cashflow 138,206,256
Full Exchange Name NasdaqGS
Full Time Employees 196
Fullday Change -0.560001
Fullday Change Percent -1.90218
Fullday Price 28.88
Gmt Off Set Milliseconds -14,400,000
Gross Margins 0.67612
Gross Profits 669,748,992
Has Pre Post Market Data 1
Held Percent Insiders 0.25447
Held Percent Institutions 0.23636
Implied Shares Outstanding 65,484,670
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 0
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Lakefront Biotherapeutics NV, a biotechnology company, develops medicines focusing on oncology and immunology primarily in the United States and Europe. The company's pipeline products comprise GLPG3667, which is in a phase 2 clinical trial in dermatomyositis and systemic lupus erythematosus; GLPG5101, a CD19 CAR-T product candidate manufactured at point-of-care, currently in a phase 1/2 trial in relapsed/refractory non-hodgkin lymphoma; and GLPG5301, a BCMA CAR-T product candidate manufactured at point-of-care, currently in phase 1/2 in relapsed/refractory multiple myeloma. The company has collaboration agreements with Gilead Sciences, Inc. The company was formerly known as Galapagos NV and changed its name to Lakefront Biotherapeutics NV in May 2026. The company was incorporated in 1999 and is headquartered in Mechelen, Belgium.
Long Name Lakefront Biotherapeutics NV
Market us_market
Market Cap 1,891,197,312
Market State CLOSED
Max Age 86,400
Message Board Id finmb_1716658
Most Recent Quarter 1,782,777,600
Name Change Date 2,026-08-29
Net Income To Common 594,324,992
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 1,930,856,949
Number Of Analyst Opinions 3
Open 29.32
Operating Cashflow -226,908,992
Operating Margins -3.5929801
Payout Ratio 0.0
Phone 32 1 534 29 00
Post Market Change 0.0
Post Market Change Percent 0.0
Post Market Price 28.88
Post Market Time 1,787,947,805
Prev Name Galapagos NV
Previous Close 29.44
Price Eps Current Year -40.676056
Price Hint 2
Price To Book 10.106698
Price To Sales Trailing12 Months 1.9091934
Profit Margins 0.60231
Quick Ratio 32.647
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key hold
Recommendation Mean 3.0
Region US
Regular Market Change -0.560001
Regular Market Change Percent -1.90218
Regular Market Day High 29.42
Regular Market Day Low 28.73
Regular Market Day Range 28.73 - 29.42
Regular Market Open 29.32
Regular Market Previous Close 29.44
Regular Market Price 28.88
Regular Market Time 1,787,947,200
Regular Market Volume 143,741
Return On Assets 0.09929
Return On Equity 0.20121
Revenue Growth -0.815
Revenue Per Share 0.7517
Sand P52 Week Change 0.20204377
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 65,484,670
Shares Percent Shares Out 0.0454
Shares Short 2,972,977
Shares Short Previous Month Date 1,784,073,600
Shares Short Prior Month 2,323,166
Short Name Lakefront Biotherapeutics
Short Percent Of Float 0.074200004
Short Ratio 13.08
Source Interval 15
Symbol LKFT
Target High Price 26.081114
Target Low Price 18.945541
Target Mean Price 23.702585
Target Median Price 26.081114
Total Cash 2,239,548,928
Total Cash Per Share 1.706
Total Debt 6,362,000
Total Revenue 990,574,016
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps 10.34
Trailing P E 2.7930367
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 30.463
Two Hundred Day Average Change -1.5830002
Two Hundred Day Average Change Percent -0.051964685
Type Disp Equity
Volume 143,741
Website https://lakefrontbio.com
Zip 2,800