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Krystal Biotech, Inc. (KRYS)

Healthcare | Biotechnology | Pittsburgh, United States | NasdaqGS
274.21 USD +10.15 (3.844%) ⇧ (April 17, 2026, 4 p.m. EDT)
After hours: 274.14 -0.07 (-0.070%) ⇩ (April 17, 2026, 5:47 p.m. EDT)

Short-term: ★★★☆☆ | Long-term: ★★★★☆ | Dividends: ☆☆☆☆☆
Hot Take | April 11, 2026, 4:25 p.m. EDT

Krystal Biotech (KRYS) presents a mixed picture. The short-term price forecast shows a slight downward trend, but the strong analyst ratings and positive fundamentals suggest potential for long-term growth. The recent pullback may offer a buying opportunity for long-term investors, especially given the positive earnings growth and strong revenue growth. However, the lack of dividends and the high overall risk should be considered. Options activity indicates a cautious market, with both bullish and bearish positions, suggesting potential for volatility in the near term.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoETS ✓0.052629
AutoARIMA0.054622
MSTL0.059996
AutoTheta0.161958

Forecast horizon: 45 days | Selected: AutoETS

Forecast Reliability
Score 46%
H-stat 6.84
Ljung-Box p 0.000
Jarque-Bera p 0.654
Excess Kurtosis -0.57
Attribute Value
Sector Healthcare
Debt to Equity Ratio 0.766
Revenue per Share 13.444
Market Cap 8,071,575,552
Trailing P/E 40.15
Forward P/E 25.92
Beta 0.54
Profit Margins 52.64%
Website https://www.krystalbio.com

As of April 11, 2026, 4:25 p.m. EDT: Options activity suggests a mix of bullish and bearish sentiment. The calls show significant positioning in the 270 strike, with high open interest and volume, indicating potential for upward movement. However, puts also show notable activity, especially around the 260 strike, suggesting some bearish speculation. The IV spikes and volume spikes in certain strikes indicate heightened uncertainty or anticipated volatility. Overall, the options market is signaling a cautious approach with potential for both upward and downward moves.


Info Dump

Attribute Value
52 Week Change 0.6935952
Address1 2,100 Wharton Street
Address2 Suite 701
All Time High 298.303
All Time Low 8.03
Ask 345.42
Ask Size 2
Audit Risk 8
Average Analyst Rating 1.2 - Strong Buy
Average Daily Volume10 Day 260,080
Average Daily Volume3 Month 287,287
Average Volume 287,287
Average Volume10Days 260,080
Beta 0.538
Bid 198.51
Bid Size 2
Board Risk 8
Book Value 41.777
City Pittsburgh
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 7
Country United States
Crypto Tradeable 0
Currency USD
Current Price 274.21
Current Ratio 9.953
Custom Price Alert Confidence HIGH
Date Short Interest 1,774,915,200
Day High 276.24
Day Low 267.31
Debt To Equity 0.766
Display Name Krystal Biotech
Earnings Call Timestamp End 1,771,335,000
Earnings Call Timestamp Start 1,771,335,000
Earnings Growth 0.116
Earnings Quarterly Growth 0.13
Earnings Timestamp 1,771,335,000
Earnings Timestamp End 1,777,897,800
Earnings Timestamp Start 1,777,897,800
Ebitda 162,919,008
Ebitda Margins 0.41867
Enterprise To Ebitda 44.177
Enterprise To Revenue 18.496
Enterprise Value 7,197,306,368
Eps Current Year 7.73589
Eps Forward 10.57953
Eps Trailing Twelve Months 6.83
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 262.6432
Fifty Day Average Change 11.566803
Fifty Day Average Change Percent 0.044039987
Fifty Two Week Change Percent 69.35952
Fifty Two Week High 298.303
Fifty Two Week High Change -24.093018
Fifty Two Week High Change Percent -0.08076693
Fifty Two Week Low 122.8
Fifty Two Week Low Change 151.40999
Fifty Two Week Low Change Percent 1.2329804
Fifty Two Week Range 122.8 - 298.303
Financial Currency USD
First Trade Date Milliseconds 1,505,914,200,000
Float Shares 23,164,464
Forward Eps 10.57953
Forward P E 25.91892
Free Cashflow 93,933,376
Full Exchange Name NasdaqGS
Full Time Employees 295
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,775,001,600
Gross Margins 0.94077003
Gross Profits 366,080,992
Has Pre Post Market Data 1
Held Percent Insiders 0.11408
Held Percent Institutions 0.9867
Implied Shares Outstanding 29,435,746
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Krystal Biotech, Inc., a commercial-stage biotechnology company, discovers, develops, manufactures, and commercializes genetic medicines to treat diseases with high unmet medical needs in the United States. The company commercializes VYJUVEK (beremagene geperpavec-svdt, or B-VEC) for the treatment of dystrophic epidermolysis bullosa (DEB). It also develops KB803 for ocular complications of dystrophic epidermolysis bullosa; KB801 for neurotrophic keratitis; KB407, which is in Phase 1 clinical trials for treating cystic fibrosis; KB111 for Hailey-Hailey disease; KB707 for solid tumors; KB304 for dynamic wrinkles; KB707 that is in Phase 1/2 clinical trials for the treatment of anti-PD-1 relapsed/refractory; KB408, which is in Phase 1 clinical trials for treating Alpha-1 antitrypsin deficiency; and KB301 that is in Phase 2 clinical trials for treating aesthetic skin conditions, as well as in open label study with ophthalmic B-VEC for treating for ocular complications of deb. Krystal Biotech, Inc. was founded in 2016 and is headquartered in Pittsburgh, Pennsylvania.
Long Name Krystal Biotech, Inc.
Market us_market
Market Cap 8,071,575,552
Market State CLOSED
Max Age 86,400
Message Board Id finmb_534062888
Most Recent Quarter 1,767,139,200
Net Income To Common 204,831,008
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 8,071,281,553
Number Of Analyst Opinions 9
Open 268.88
Operating Cashflow 200,864,992
Operating Margins 0.41333
Overall Risk 8
Payout Ratio 0.0
Phone 412 586 5830
Post Market Change -0.06997681
Post Market Change Percent -0.025519423
Post Market Price 274.14
Post Market Time 1,776,462,449
Previous Close 264.06
Price Eps Current Year 35.44647
Price Hint 2
Price To Book 6.563659
Price To Sales Trailing12 Months 20.74262
Profit Margins 0.52638
Quick Ratio 9.279
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.18182
Region US
Regular Market Change 10.15
Regular Market Change Percent 3.84382
Regular Market Day High 276.24
Regular Market Day Low 267.31
Regular Market Day Range 267.31 - 276.24
Regular Market Open 268.88
Regular Market Previous Close 264.06
Regular Market Price 274.21
Regular Market Time 1,776,456,001
Regular Market Volume 307,410
Return On Assets 0.08437
Return On Equity 0.18913999
Revenue Growth 0.175
Revenue Per Share 13.444
Sand P52 Week Change 0.38150132
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 8
Shares Outstanding 29,435,746
Shares Percent Shares Out 0.1066
Shares Short 3,136,891
Shares Short Previous Month Date 1,772,150,400
Shares Short Prior Month 2,947,930
Short Name Krystal Biotech, Inc.
Short Percent Of Float 0.1751
Short Ratio 11.08
Source Interval 15
State PA
Symbol KRYS
Target High Price 371.0
Target Low Price 241.0
Target Mean Price 314.0
Target Median Price 310.0
Total Cash 827,790,976
Total Cash Per Share 28.318
Total Debt 9,339,000
Total Revenue 389,129,984
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps 6.83
Trailing P E 40.147877
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 211.56717
Two Hundred Day Average Change 62.642822
Two Hundred Day Average Change Percent 0.29608953
Type Disp Equity
Volume 307,410
Website https://www.krystalbio.com
Zip 15,203