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Krystal Biotech, Inc. (KRYS)

Healthcare | Biotechnology | Pittsburgh, United States | NasdaqGS
363.44 USD -2.37 (-0.648%) ⇩ (July 13, 2026, 4 p.m. EDT)
After hours: 365.05 +1.61 (0.443%) ⇧ (July 13, 2026, 7:46 p.m. EDT)

Short-term:★★★★☆Long-term:★★★★⯪Dividends:☆☆☆☆☆
Hot Take | July 11, 2026, 3:38 a.m. EDT

The long-term investment case is exceptionally strong, driven by a fortress balance sheet with minimal debt and robust cash generation, alongside impressive revenue and earnings growth rates that exceed industry norms. While the valuation is rich, the underlying business quality supports a premium price, though the recent annual contraction in the trailing anchor year warrants caution. For the short term, momentum is clearly building as the stock trades well above its moving averages and options flow indicates bullish positioning near current highs. There is no dividend income to rely on, making capital appreciation the sole driver of returns. Investors should be aware that the statistical forecast model offers low confidence, suggesting the immediate price move may be driven more by sentiment than predictive certainty.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoETS ✓0.112549
MSTL_740.115328
AutoTheta0.125521
MSTL_74_1260.129470
MSTL0.142815
AutoARIMA0.153023
MSTL_1260.157918

Forecast horizon: 60 days | Selected: AutoETS

Forecast Reliability
Score 32%
H-stat 16.45
Ljung-Box p 0.000
Jarque-Bera p 0.210
Excess Kurtosis -0.84
Attribute Value
Sector Healthcare
Debt to Equity Ratio 0.714
Revenue per Share 14.359
Market Cap 10,714,122,240
Trailing P/E 48.72
Forward P/E 35.59
Beta 0.50
Profit Margins 53.92%
Website https://www.krystalbio.com

As of July 11, 2026, 3:38 a.m. EDT: Speculators are positioning for upside continuation with call volume concentrated at strikes above the current price (380 to 420), while heavy put open interest at lower strikes (250 to 300) for later expirations suggests a defined downside floor. Implied volatility remains elevated across the board.


Info Dump

Attribute Value
52 Week Change 1.4320855
Address1 2,100 Wharton Street
Address2 Suite 701
All Time High 382.535
All Time Low 8.03
Ask 372.44
Ask Size 1
Audit Risk 6
Average Analyst Rating 1.2 - Strong Buy
Average Daily Volume10 Day 374,520
Average Daily Volume3 Month 316,524
Average Volume 316,524
Average Volume10Days 374,520
Beta 0.497
Bid 371.0
Bid Size 2
Board Risk 8
Book Value 43.372
City Pittsburgh
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 8
Country United States
Crypto Tradeable 0
Currency USD
Current Price 363.44
Current Ratio 9.459
Custom Price Alert Confidence HIGH
Date Short Interest 1,782,777,600
Day High 367.79
Day Low 353.49
Debt To Equity 0.714
Display Name Krystal Biotech
Earnings Call Timestamp End 1,777,897,800
Earnings Call Timestamp Start 1,777,897,800
Earnings Growth 0.525
Earnings Quarterly Growth 0.565
Earnings Timestamp 1,777,897,800
Earnings Timestamp End 1,785,760,200
Earnings Timestamp Start 1,785,760,200
Ebitda 180,468,000
Ebitda Margins 0.43245998
Enterprise To Ebitda 54.856
Enterprise To Revenue 23.723
Enterprise Value 9,899,829,248
Eps Current Year 8.29113
Eps Forward 10.21264
Eps Trailing Twelve Months 7.46
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 320.9559
Fifty Day Average Change 42.4841
Fifty Day Average Change Percent 0.1323674
Fifty Two Week Change Percent 143.20856
Fifty Two Week High 382.535
Fifty Two Week High Change -19.095001
Fifty Two Week High Change Percent -0.049917005
Fifty Two Week Low 130.5
Fifty Two Week Low Change 232.94
Fifty Two Week Low Change Percent 1.7849809
Fifty Two Week Range 130.5 - 382.535
Financial Currency USD
First Trade Date Milliseconds 1,505,914,200,000
Float Shares 23,420,192
Forward Eps 10.21264
Forward P E 35.587273
Free Cashflow 137,491,504
Full Exchange Name NasdaqGS
Full Time Employees 295
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,782,864,000
Gross Margins 0.94166
Gross Profits 392,960,000
Has Pre Post Market Data 1
Held Percent Insiders 0.109689996
Held Percent Institutions 0.99518996
Implied Shares Outstanding 29,479,756
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Krystal Biotech, Inc., a commercial-stage biotechnology company, discovers, develops, manufactures, and commercializes genetic medicines to treat diseases with high unmet medical needs in the United States. The company commercializes VYJUVEK (beremagene geperpavec-svdt, or B-VEC) for the treatment of dystrophic epidermolysis bullosa (DEB). It also develops KB803 for ocular complications of dystrophic epidermolysis bullosa; KB801 for neurotrophic keratitis; KB407, which is in Phase 1 clinical trials for treating cystic fibrosis; KB111 for Hailey-Hailey disease; KB707 for solid tumors; KB304 for dynamic wrinkles; KB707 that is in Phase 1/2 clinical trials for the treatment of anti-PD-1 relapsed/refractory; KB408, which is in Phase 1 clinical trials for treating Alpha-1 antitrypsin deficiency; and KB301 that is in Phase 2 clinical trials for treating aesthetic skin conditions, as well as in open label study with ophthalmic B-VEC for treating for ocular complications of deb. Krystal Biotech, Inc. was founded in 2016 and is headquartered in Pittsburgh, Pennsylvania.
Long Name Krystal Biotech, Inc.
Market us_market
Market Cap 10,714,122,240
Market State POSTPOST
Max Age 86,400
Message Board Id finmb_534062888
Most Recent Quarter 1,774,915,200
Net Income To Common 225,030,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 10,783,694,744
Number Of Analyst Opinions 9
Open 364.98
Operating Cashflow 250,278,000
Operating Margins 0.46141997
Overall Risk 8
Payout Ratio 0.0
Phone 412 586 5830
Post Market Change 1.6099854
Post Market Change Percent 0.44298518
Post Market Price 365.05
Post Market Time 1,783,986,384
Previous Close 365.81
Price Eps Current Year 43.834797
Price Hint 2
Price To Book 8.3796
Price To Sales Trailing12 Months 25.674622
Profit Margins 0.53925
Quick Ratio 8.816
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.18182
Region US
Regular Market Change -2.37
Regular Market Change Percent -0.647876
Regular Market Day High 367.79
Regular Market Day Low 353.49
Regular Market Day Range 353.49 - 367.79
Regular Market Open 364.98
Regular Market Previous Close 365.81
Regular Market Price 363.44
Regular Market Time 1,783,972,800
Regular Market Volume 373,944
Return On Assets 0.0904
Return On Equity 0.19902
Revenue Growth 0.319
Revenue Per Share 14.359
Sand P52 Week Change 0.20847368
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 8
Shares Outstanding 29,479,756
Shares Percent Shares Out 0.1193
Shares Short 3,517,595
Shares Short Previous Month Date 1,780,012,800
Shares Short Prior Month 3,147,863
Short Name Krystal Biotech, Inc.
Short Percent Of Float 0.19590001
Short Ratio 9.04
Source Interval 15
State PA
Symbol KRYS
Target High Price 403.0
Target Low Price 241.0
Target Mean Price 349.77777
Target Median Price 364.0
Total Cash 823,404,992
Total Cash Per Share 27.931
Total Debt 9,112,000
Total Revenue 417,304,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps 7.46
Trailing P E 48.7185
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 259.18875
Two Hundred Day Average Change 104.25125
Two Hundred Day Average Change Percent 0.40222135
Type Disp Equity
Volume 373,944
Website https://www.krystalbio.com
Zip 15,203