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Kailera Therapeutics, Inc. (KLRA)

Healthcare | Biotechnology | Waltham, United States | NasdaqGS
11.71 USD +0.97 (9.032%) ⇧ (Oct. 15, 2026, 4 p.m. EDT)

Short-term:★☆☆☆☆Long-term:★★⯪☆☆Dividends:☆☆☆☆☆
Hot Take ↕ | Oct. 10, 2026, 9:53 a.m. EDT

Kailera Therapeutics presents a classic biotech dilemma: a massive analyst consensus target price of $42.40 clashes violently with the reality of negative earnings, negative forward P/E, and a stock trading near its 52-week lows. While the company boasts a fortress balance sheet with $916M in cash against minimal debt and a pristine current ratio of 11x, the market is pricing in significant execution risk, evidenced by the heavy short interest and the stock's failure to recover from its IPO highs. The recent price action shows a distinct downtrend, closing the last session near the $10 level after failing to breach the $13 resistance zone. With no dividend to provide income and a statistical forecast leaning slightly negative despite low confidence, the short-term outlook remains bearish as the stock digests the gap between its lofty analyst expectations and its deteriorating technical structure. Long-term, the business fundamentals are sound enough to warrant a neutral hold pending clinical milestones, but the current valuation implies the market expects a long road to profitability.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoTheta ✓0.108118
AutoETS0.132238
AutoARIMA0.132747
MSTL0.134103

Forecast horizon: 45 days | Selected: AutoTheta

Forecast Reliability
Score 34%
H-stat 18.06
Ljung-Box p 0.000
Jarque-Bera p 0.068
Excess Kurtosis -0.47
Attribute Value
Sector Healthcare
Debt to Equity Ratio 0.913
Market Cap 1,518,127,488
Forward P/E -2.73
Website https://www.kailera.com

As of Oct. 10, 2026, 9:53 a.m. EDT: Options activity is virtually dormant with negligible open interest and volume across both calls and puts. The lack of positioning suggests speculators are currently sidelined or waiting for clinical data clarity rather than betting on immediate directional moves.


Info Dump

Attribute Value
52 Week Change -0.58692306
Address1 180 Third Avenue
Address2 4th Floor
All Time High 28.23
All Time Low 9.76
Ask 13.54
Ask Size 2
Average Analyst Rating 1.2 - Strong Buy
Average Daily Volume10 Day 1,516,890
Average Daily Volume3 Month 933,990
Average Volume 933,990
Average Volume10Days 1,516,890
Bid 8.46
Bid Size 2
Book Value 8.629
City Waltham
Compensation As Of Epoch Date 1,767,139,200
Country United States
Crypto Tradeable 0
Currency USD
Current Price 11.71
Current Ratio 11.108
Custom Price Alert Confidence HIGH
Date Short Interest 1,790,726,400
Day High 11.76
Day Low 10.5
Debt To Equity 0.913
Display Name Kailera Therapeutics
Dividend Yield 0.0
Earnings Timestamp 1,793,822,400
Earnings Timestamp End 1,793,822,400
Earnings Timestamp Start 1,793,822,400
Ebitda -312,878,016
Ebitda Margins 0.0
Enterprise To Ebitda -1.955
Enterprise Value 611,602,432
Eps Current Year -4.09671
Eps Forward -4.296
Eps Trailing Twelve Months -4.51
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 15
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 14.6584
Fifty Day Average Change -2.9483995
Fifty Day Average Change Percent -0.20114061
Fifty Two Week Change Percent -58.692307
Fifty Two Week High 28.23
Fifty Two Week High Change -16.52
Fifty Two Week High Change Percent -0.5851931
Fifty Two Week Low 9.76
Fifty Two Week Low Change 1.9499998
Fifty Two Week Low Change Percent 0.19979505
Fifty Two Week Range 9.76 - 28.23
Financial Currency USD
First Trade Date Milliseconds 1,776,432,600,000
Float Shares 58,478,373
Forward Eps -4.296
Forward P E -2.7257915
Full Exchange Name NasdaqGS
Full Time Employees 145
Fullday Change 1.0100002
Fullday Change Percent 9.4040985
Fullday Price 11.71
Gmt Off Set Milliseconds -14,400,000
Gross Margins 0.0
Has Pre Post Market Data 1
Held Percent Insiders 0.089090005
Held Percent Institutions 0.90391
Implied Shares Outstanding 129,643,676
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Ipo Expected Date 2,026-04-17
Is Earnings Date Estimate 0
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Kailera Therapeutics, Inc. operates as a clinical-stage biopharmaceutical company developing therapies for obesity and related conditions. The company develops clinical- and preclinical-stage therapies, with a product pipeline that includes injectable peptides, oral peptides, and oral small molecules. Key programs include KAI-9531, an injectable GLP-1/GIP receptor dual agonist; KAI-7535, an oral small molecule GLP-1 receptor agonist; and KAI-4729, an injectable GLP-1/GIP/glucagon receptor tri-agonist. Kailera Therapeutics holds exclusive rights for global development and commercialization of four metabolic disease assets outside of Greater China, with therapies delivered through oral and injectable formulations. The company was founded in 2024 and is based in Waltham, Massachusetts.
Long Name Kailera Therapeutics, Inc.
Market us_market
Market Cap 1,518,127,488
Market State PRE
Max Age 86,400
Message Board Id finmb_1899116257
Most Recent Quarter 1,782,777,600
Net Income To Common -292,196,992
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 1,702,221,465
Number Of Analyst Opinions 5
Open 10.55
Operating Cashflow -221,615,008
Operating Margins 0.0
Phone 781 317 0290
Previous Close 10.74
Price Eps Current Year -2.858391
Price Hint 2
Price To Book 1.3570518
Profit Margins 0.0
Quick Ratio 11.032
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.16667
Region US
Regular Market Change 0.97
Regular Market Change Percent 9.03166
Regular Market Day High 11.76
Regular Market Day Low 10.5
Regular Market Day Range 10.5 - 11.76
Regular Market Open 10.55
Regular Market Previous Close 10.74
Regular Market Price 11.71
Regular Market Time 1,792,094,401
Regular Market Volume 1,174,315
Sand P52 Week Change 0.16207206
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 129,643,676
Shares Percent Shares Out 0.067
Shares Short 8,683,381
Shares Short Previous Month Date 1,788,134,400
Shares Short Prior Month 5,660,876
Short Name Kailera Therapeutics, Inc.
Short Percent Of Float 0.067
Short Ratio 7.26
Source Interval 15
State MA
Symbol KLRA
Target High Price 57.0
Target Low Price 30.0
Target Mean Price 42.4
Target Median Price 41.0
Total Cash 916,740,992
Total Cash Per Share 7.071
Total Debt 10,216,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -4.51
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 18.48568
Two Hundred Day Average Change -6.7756796
Two Hundred Day Average Change Percent -0.36653668
Type Disp Equity
Volume 1,174,315
Website https://www.kailera.com
Zip 2,451