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Iovance Biotherapeutics, Inc. (IOVA)

Healthcare | Biotechnology | San Carlos, United States | NasdaqGM
3.86 USD +0.06 (1.579%) ⇧ (April 17, 2026, 4 p.m. EDT)
After hours: 3.85 -0.01 (-0.010%) ⇩ (April 17, 2026, 7:58 p.m. EDT)

Short-term: ★★☆☆☆ | Long-term: ★☆☆☆☆ | Dividends: ☆☆☆☆☆
Hot Take | April 11, 2026, 3:13 p.m. EDT

IOVA is a high-risk stock with significant volatility and negative fundamentals. The recent price movements show a lack of clear momentum, and the stock is trading below its 52-week low. The options data suggests a mix of bullish and bearish sentiment, but the overall fundamentals are weak, with negative earnings and low profitability. The lack of dividend payouts further reduces its appeal for income-focused investors. While there is potential for short-term price movement, the long-term outlook remains bleak, and the stock should be avoided unless there is a significant catalyst.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoTheta ✓0.172032
AutoARIMA0.214715
AutoETS0.214716
MSTL0.216722

Forecast horizon: 45 days | Selected: AutoTheta

Forecast Reliability
Score 80%
H-stat 0.47
Ljung-Box p 0.000
Jarque-Bera p 0.642
Excess Kurtosis -0.34
Attribute Value
Sector Healthcare
Debt to Equity Ratio 7.078
Revenue per Share 0.737
Market Cap 1,590,171,776
Forward P/E -16.31
Beta 0.76
Profit Margins -148.38%
Website https://www.iovance.com

As of April 11, 2026, 3:13 p.m. EDT: The options activity suggests mixed signals. The calls show increased volume and open interest for strikes above the current price, indicating potential bullish sentiment, especially around the $4.0 strike. However, the puts also show significant open interest and volume for strikes below the current price, suggesting some bearish sentiment. The overall volatility and open interest indicate a market that is uncertain about future price direction, with both bullish and bearish speculation present.


Info Dump

Attribute Value
52 Week Change 0.2337662
Address1 825 Industrial Road
Address2 Suite 100
All Time High 165.0
All Time Low 1.0
Ask 3.87
Ask Size 2
Audit Risk 8
Average Analyst Rating 1.7 - Buy
Average Daily Volume10 Day 16,939,280
Average Daily Volume3 Month 15,771,801
Average Volume 15,771,801
Average Volume10Days 16,939,280
Beta 0.764
Bid 3.83
Bid Size 8
Board Risk 6
Book Value 1.696
City San Carlos
Compensation As Of Epoch Date 1,735,603,200
Compensation Risk 8
Country United States
Crypto Tradeable 0
Currency USD
Current Price 3.86
Current Ratio 3.2
Custom Price Alert Confidence HIGH
Date Short Interest 1,774,915,200
Day High 3.97
Day Low 3.85
Debt To Equity 7.078
Display Name Iovance Biotherapeutics
Earnings Call Timestamp End 1,771,939,800
Earnings Call Timestamp Start 1,771,939,800
Earnings Timestamp 1,771,939,800
Earnings Timestamp End 1,778,157,000
Earnings Timestamp Start 1,778,157,000
Ebitda -362,273,984
Ebitda Margins -1.3748399
Enterprise To Ebitda -3.706
Enterprise To Revenue 5.095
Enterprise Value 1,342,637,824
Eps Current Year -0.51225
Eps Forward -0.23671
Eps Trailing Twelve Months -1.09
Esg Populated 0
Exchange NGM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 3.5622
Fifty Day Average Change 0.29779983
Fifty Day Average Change Percent 0.08359997
Fifty Two Week Change Percent 23.37662
Fifty Two Week High 5.63
Fifty Two Week High Change -1.7700002
Fifty Two Week High Change Percent -0.31438723
Fifty Two Week Low 1.64
Fifty Two Week Low Change 2.2199998
Fifty Two Week Low Change Percent 1.3536584
Fifty Two Week Range 1.64 - 5.63
Financial Currency USD
First Trade Date Milliseconds 1,287,149,400,000
Float Shares 353,409,504
Forward Eps -0.23671
Forward P E -16.306873
Free Cashflow -162,422,128
Full Exchange Name NasdaqGM
Full Time Employees 975
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,775,001,600
Gross Margins 0.34276
Gross Profits 90,318,000
Has Pre Post Market Data 1
Held Percent Insiders 0.00402
Held Percent Institutions 0.71139
Implied Shares Outstanding 411,961,607
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Last Split Date 1,380,153,600
Last Split Factor 1:100
Long Business Summary Iovance Biotherapeutics, Inc., a commercial-stage biopharmaceutical company, develops and commercializes cell therapies using autologous tumor infiltrating lymphocyte for the treatment of metastatic melanoma and other solid tumor cancers in the United States and internationally. The company offers Amtagvi, an individualized T cell therapy for solid tumor cancer and for the treatment of adult patients with previously treated advanced, or unresectable or metastatic melanomal; and Proleukin, an interleukin-2 product for the treatment of patients with metastatic melanoma and metastatic renal cell carcinoma. It also develops lifileucel for the treatment of melanoma, cervical cancer, non-small cell lung cancer (NSCLC), endometrial cancer, and head and neck squamous cell carcinoma (HNSCC); LN-145-S1 to treat melanoma and HNSCC; LN-145 Gen 3 and core biopsy for the treatment of NSCLC; LN-145 Gen 3 to treat melanoma and HNSCC; IOV-2001 to treat chronic lymphocytic leukemia and small lymphocytic lymphoma; IOV-4001 for the treatment of melanoma and NSCLC; and IOV-3001 for use in the TIL therapy treatment regimen. The company has collaborations and licensing agreements with National Institutes of Health; the National Cancer Institute; Cellectis S.A.; Novartis Pharma AG; and Boehringer Ingelheim Biopharmaceuticals GmbH. The company was formerly known as Lion Biotechnologies, Inc. and changed its name to Iovance Biotherapeutics, Inc. in June 2017. Iovance Biotherapeutics, Inc. was incorporated in 2007 and is headquartered in San Carlos, California.
Long Name Iovance Biotherapeutics, Inc.
Market us_market
Market Cap 1,590,171,776
Market State CLOSED
Max Age 86,400
Message Board Id finmb_40424708
Most Recent Quarter 1,767,139,200
Net Income To Common -390,977,984
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 1,588,111,994
Number Of Analyst Opinions 10
Open 3.93
Operating Cashflow -302,408,000
Operating Margins -0.84660006
Overall Risk 5
Payout Ratio 0.0
Phone 650 260 7120
Post Market Change -0.00999999
Post Market Change Percent -0.25906712
Post Market Price 3.85
Post Market Time 1,776,470,338
Previous Close 3.8
Price Eps Current Year -7.5353827
Price Hint 4
Price To Book 2.2759433
Price To Sales Trailing12 Months 6.034762
Profit Margins -1.48378
Quick Ratio 2.742
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key buy
Recommendation Mean 1.72727
Region US
Regular Market Change 0.0599999
Regular Market Change Percent 1.57895
Regular Market Day High 3.97
Regular Market Day Low 3.85
Regular Market Day Range 3.85 - 3.97
Regular Market Open 3.93
Regular Market Previous Close 3.8
Regular Market Price 3.86
Regular Market Time 1,776,456,001
Regular Market Volume 10,492,787
Return On Assets -0.27296
Return On Equity -0.55498004
Revenue Growth 0.177
Revenue Per Share 0.737
Sand P52 Week Change 0.36506534
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 3
Shares Outstanding 411,961,607
Shares Percent Shares Out 0.269
Shares Short 110,832,243
Shares Short Previous Month Date 1,772,150,400
Shares Short Prior Month 130,927,595
Short Name Iovance Biotherapeutics, Inc.
Short Percent Of Float 0.2894
Short Ratio 6.52
Source Interval 15
State CA
Symbol IOVA
Target High Price 16.0
Target Low Price 4.0
Target Mean Price 9.0
Target Median Price 9.5
Total Cash 296,980,000
Total Cash Per Share 0.721
Total Debt 49,444,000
Total Revenue 263,502,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -1.09
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 2.6684
Two Hundred Day Average Change 1.1915998
Two Hundred Day Average Change Percent 0.44655967
Type Disp Equity
Volume 10,492,787
Website https://www.iovance.com
Zip 94,070