| Browse All

Inovio Pharmaceuticals, Inc. (INO)

Healthcare | Biotechnology | Plymouth Meeting, United States | NasdaqCM
1.19 USD +0.03 (2.586%) ⇧ (April 17, 2026, 4 p.m. EDT)
After hours: 1.21 +0.02 (1.655%) ⇧ (April 17, 2026, 7:59 p.m. EDT)

Short-term: ★★☆☆☆ | Long-term: ★☆☆☆☆ | Dividends: ☆☆☆☆☆
Hot Take | April 19, 2026, 1:15 a.m. EDT

This is a 'sell on any strength' diagnosis. Fundamentally, INO is bleeding value with -100% revenue growth and massive debt-to-equity (38x) despite a 1.4 current ratio; the stock has lost ~88% value year-over-year. While the stock is technically oversold and showing signs of a trend reversal (news mentions 'PDUFA inflection' and 'trend reversal'), the sheer dilution from recent $17.5M stock offerings and the heavy put activity suggest the $1.19 level is fragile. The massive 5/08 volatility play suggests a binary event is coming, but without the product data (PDUFA date) providing a definitive 'yes,' the probability of collapse outweighs the probability of a recovery.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
MSTL ✓0.113870
AutoETS0.120506
AutoARIMA0.120509
AutoTheta0.171316

Forecast horizon: 45 days | Selected: MSTL

Forecast Reliability
Score 19%
H-stat 9.63
Ljung-Box p 0.000
Jarque-Bera p 0.000
Excess Kurtosis 2.81
Attribute Value
Sector Healthcare
Debt to Equity Ratio 38.877
Revenue per Share 0.001
Market Cap 97,094,424
Forward P/E -2.05
Beta 1.70
Website https://www.inovio.com

As of April 19, 2026, 1:15 a.m. EDT: Options flow reveals a distinct contradiction. Near-term expiration (4/24 to 5/01) shows heavy put volume at strikes below the current price ($1.0 ATM), suggesting a defensive hedge against further downside. However, a massive 'straddle' was placed on the 5/08 expiration across the board (880 Call Vol + 550 Put Vol), indicating an expectation of high volatility rather than a specific directional bias. Single massive flow on the 1.5 strike call for 5/08 dominates the volume profile, slightly tipping the sentiment toward a bounce or gap-up in May. Lower-dated OTM calls (3.0 strike) show significant Open Interest, implying a speculative long-term upside thesis despite the current price crush.


Info Dump

Attribute Value
52 Week Change -0.33146065
Address1 660 West Germantown Pike
Address2 Suite 110
All Time High 2,352.0
All Time Low 1.03
Ask 1.35
Ask Size 1
Average Analyst Rating 2.0 - Buy
Average Daily Volume10 Day 3,133,080
Average Daily Volume3 Month 1,566,770
Average Volume 1,566,770
Average Volume10Days 3,133,080
Beta 1.703
Bid 1.01
Bid Size 1
Book Value 0.349
City Plymouth Meeting
Compensation As Of Epoch Date 1,767,139,200
Country United States
Crypto Tradeable 0
Currency USD
Current Price 1.19
Current Ratio 1.4
Custom Price Alert Confidence HIGH
Date Short Interest 1,774,915,200
Day High 1.2
Day Low 1.16
Debt To Equity 38.877
Display Name Inovio Pharmaceuticals
Earnings Call Timestamp End 1,773,347,400
Earnings Call Timestamp Start 1,773,347,400
Earnings Timestamp 1,773,345,600
Earnings Timestamp End 1,778,702,400
Earnings Timestamp Start 1,778,702,400
Ebitda -85,404,192
Ebitda Margins 0.0
Enterprise To Ebitda -0.387
Enterprise To Revenue 506.172
Enterprise Value 33,074,790
Eps Current Year -1.0425
Eps Forward -0.58
Eps Trailing Twelve Months -1.81
Esg Populated 0
Exchange NCM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 1.5568
Fifty Day Average Change -0.36679995
Fifty Day Average Change Percent -0.23561148
Fifty Two Week Change Percent -33.146065
Fifty Two Week High 2.98
Fifty Two Week High Change -1.79
Fifty Two Week High Change Percent -0.6006711
Fifty Two Week Low 1.03
Fifty Two Week Low Change 0.16000009
Fifty Two Week Low Change Percent 0.1553399
Fifty Two Week Range 1.03 - 2.98
Financial Currency USD
First Trade Date Milliseconds 913,127,400,000
Float Shares 68,803,152
Forward Eps -0.58
Forward P E -2.0517242
Free Cashflow -38,681,548
Full Exchange Name NasdaqCM
Full Time Employees 112
Gmt Off Set Milliseconds -14,400,000
Gross Margins 0.0
Gross Profits -54,141,532
Has Pre Post Market Data 1
Held Percent Insiders 0.0042
Held Percent Institutions 0.42139998
Implied Shares Outstanding 81,591,956
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Ir Website http://ir.inovio.com/
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Last Split Date 1,706,140,800
Last Split Factor 1:12
Long Business Summary Inovio Pharmaceuticals, Inc., a biotechnology company, focuses on the discovery, development, and commercialization of DNA medicines to treat and protect people from diseases associated with human papillomavirus (HPV), cancer, and infectious diseases. Its DNA medicines platform uses SynCon, to help engineer precisely designed plasmid DNA plasmids, as well as CELLECTRA smart devices technology that facilitates delivery of the DNA plasmids. The company's lead product candidate is INO-3107 for HPV-related recurrent respiratory papillomatosis and is under Phase 1/2 trial. Its products in pipeline include VGX-3100 for the treatment of HPV-related cervical high-grade squamous intraepithelial lesions; INO-3112 for the treatment of HPV-related Oropharyngeal squamous cell carcinoma and is under Phase 2 trial; INO-5401 for the treatment of glioblastoma multiforme and is under Phase 2 trial; INO-4201 for Ebola Virus Disease and is under Phase 1b trial; INO-4800 for COVID-19 and is under Phase 2/3 trial; and INO-6160 for the treatment of human immunodeficiency virus and is under Phase 1 trial. The company's partners and collaborators ApolloBio Corporation, AstraZeneca, Coherus Biosciences, Defense Advanced Research Projects Agency, HIV Vaccines Trial Network, Kaneka Eurogentec, National Institutes of Health, National Institute of Allergy and Infectious Diseases, Plumbline Life Sciences, Regeneron Pharmaceuticals, Richter BioLogics, the University of Pennsylvania, and The Wistar Institute. The company was incorporated in 1983 and is headquartered in Plymouth Meeting, Pennsylvania.
Long Name Inovio Pharmaceuticals, Inc.
Market us_market
Market Cap 97,094,424
Market State CLOSED
Max Age 86,400
Message Board Id finmb_28922
Most Recent Quarter 1,767,139,200
Net Income To Common -84,945,904
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 97,502,387
Number Of Analyst Opinions 6
Open 1.18
Operating Cashflow -88,629,432
Operating Margins -1,328.7131
Payout Ratio 0.0
Phone 267 440 4200
Post Market Change 0.019699931
Post Market Change Percent 1.6554563
Post Market Price 1.2097
Post Market Time 1,776,470,392
Previous Close 1.16
Price Eps Current Year -1.1414869
Price Hint 4
Price To Book 3.409742
Price To Sales Trailing12 Months 1,485.9193
Profit Margins 0.0
Quick Ratio 1.34
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key buy
Recommendation Mean 2.0
Region US
Regular Market Change 0.0300001
Regular Market Change Percent 2.58621
Regular Market Day High 1.2
Regular Market Day Low 1.16
Regular Market Day Range 1.16 - 1.2
Regular Market Open 1.18
Regular Market Previous Close 1.16
Regular Market Price 1.19
Regular Market Time 1,776,456,001
Regular Market Volume 2,031,271
Return On Assets -0.57879
Return On Equity -1.8346801
Revenue Growth -1.0
Revenue Per Share 0.001
Sand P52 Week Change 0.38150132
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 81,591,956
Shares Percent Shares Out 0.14310001
Shares Short 9,884,839
Shares Short Previous Month Date 1,772,150,400
Shares Short Prior Month 10,960,650
Short Name Inovio Pharmaceuticals, Inc.
Short Percent Of Float 0.1668
Short Ratio 14.51
Source Interval 15
State PA
Symbol INO
Target High Price 13.0
Target Low Price 1.8
Target Mean Price 6.96667
Target Median Price 6.0
Total Cash 58,512,464
Total Cash Per Share 0.847
Total Debt 9,367,826
Total Revenue 65,343
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -1.81
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 1.87935
Two Hundred Day Average Change -0.6893499
Two Hundred Day Average Change Percent -0.3668023
Type Disp Equity
Volume 2,031,271
Website https://www.inovio.com
Zip 19,462