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Werewolf Therapeutics, Inc. (HOWL)

Healthcare | Biotechnology | Watertown, United States | NasdaqCM
0.99 USD +0.01 (0.947%) ⇧ (Oct. 13, 2026, 4 p.m. EDT)
After hours: 1.00 +0.01 (0.898%) ⇧ (Oct. 13, 2026, 7:47 p.m. EDT)

Short-term:★★☆☆☆Long-term:⯪☆☆☆☆Dividends:☆☆☆☆☆
Hot Take ↕ | Oct. 10, 2026, 5:59 a.m. EDT

The investment case here is bifurcated between a speculative gamble and a fundamental reality check. On the short end, the options market is screaming for a moonshot; the concentration of open interest in far-out strikes ($2.50) indicates traders are betting on a binary event or a sudden re-rating that ignores current valuation. However, the long-term outlook is dire. The company has suffered four consecutive years of declining annual returns, with the stock down nearly 90% over the last four years. Fundamentals are broken: negative earnings, negative free cash flow, and negative gross margins indicate a business model that is currently burning capital without generating value. While the balance sheet shows some liquidity, the trajectory is unmistakably downward. The lack of a dividend reflects the company's need to retain cash for operations rather than returning value. Investors here are either buying a lottery ticket on a specific catalyst or ignoring the structural deterioration of the business.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoETS ✓0.599077
AutoARIMA0.601758
MSTL0.619502
AutoTheta0.669531

Forecast horizon: 45 days | Selected: AutoETS

Forecast Reliability
Score 21%
H-stat 40.78
Ljung-Box p 0.000
Jarque-Bera p 0.030
Excess Kurtosis -1.86
Attribute Value
Sector Healthcare
Revenue per Share 0.439
Market Cap 48,168,936
Forward P/E -1.68
Beta 0.51
Profit Margins -164.82%
Website https://werewolftx.com

As of Oct. 10, 2026, 5:59 a.m. EDT: Speculators are overwhelmingly positioning for a massive upside move, evidenced by heavy open interest in deep out-of-the-money calls (strikes $2.50+) across multiple expirations, while put activity is negligible. This 'lottery ticket' style positioning suggests a belief in a binary event or catalyst that could drive the price significantly higher, despite the lack of traditional bullish volume in near-term ATM calls.


Info Dump

Attribute Value
52 Week Change -0.41197604
Address1 200 Talcott Ave
Address2 2nd Floor
All Time High 23.99
All Time Low 0.27
Ask 1.2
Ask Size 2
Average Daily Volume10 Day 561,320
Average Daily Volume3 Month 6,794,343
Average Volume 6,794,343
Average Volume10Days 561,320
Beta 0.511
Bid 0.651
Bid Size 2
Book Value 0.335
City Watertown
Compensation As Of Epoch Date 1,767,139,200
Country United States
Crypto Tradeable 0
Currency USD
Current Price 0.9911
Current Ratio 2.911
Custom Price Alert Confidence HIGH
Date Short Interest 1,790,726,400
Day High 1.0101
Day Low 0.97
Display Name Werewolf Therapeutics
Dividend Yield 0.0
Earnings Timestamp 1,785,501,000
Earnings Timestamp End 1,793,363,400
Earnings Timestamp Start 1,793,363,400
Ebitda -21,921,000
Ebitda Margins -1.04386
Enterprise To Ebitda -1.194
Enterprise To Revenue 1.247
Enterprise Value 26,179,534
Eps Current Year -0.89
Eps Forward -0.59
Eps Trailing Twelve Months -0.73
Esg Populated 0
Exchange NCM
Exchange Data Delayed By 15
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 0.79486
Fifty Day Average Change 0.19624001
Fifty Day Average Change Percent 0.24688625
Fifty Two Week Change Percent -41.197605
Fifty Two Week High 1.83
Fifty Two Week High Change -0.8389
Fifty Two Week High Change Percent -0.4584153
Fifty Two Week Low 0.27
Fifty Two Week Low Change 0.7211
Fifty Two Week Low Change Percent 2.6707406
Fifty Two Week Range 0.27 - 1.83
Financial Currency USD
First Trade Date Milliseconds 1,619,789,400,000
Float Shares 45,379,864
Forward Eps -0.59
Forward P E -1.6798306
Free Cashflow -12,233,750
Full Exchange Name NasdaqCM
Full Time Employees 39
Fullday Change 0.01819998
Fullday Change Percent 1.853736
Fullday Price 0.9911
Gmt Off Set Milliseconds -14,400,000
Gross Margins -0.2469
Gross Profits -5,185,000
Has Pre Post Market Data 1
Held Percent Insiders 0.06624
Held Percent Institutions 0.39215
Implied Shares Outstanding 48,601,487
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Ipo Expected Date 2,021-04-30
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Werewolf Therapeutics, Inc., a biopharmaceutical company, engages in the development of therapeutics engineered to stimulate the body's immune system for the treatment of cancer and other immune-mediated conditions. The company designs conditionally activated molecules that stimulate adaptive and innate immunity for addressing the limitations of conventional proinflammatory immune therapies through its proprietary PREDATOR platform. Its lead product candidates are WTX-124, a conditionally activated Interleukin-2 INDUKINE molecule for the treatment of advanced or metastatic solid tumors; and WTX-330, a conditionally activated Interleukin-12 INDUKINE molecule for the treatment of advanced or metastatic solid tumors and lymphoma. The company is also developing JZP898, a conditionally activated interferon alpha INDUKINE molecule for the treatment of cancer; WTX-921, a conditionally activated IL-10 INDUKINE molecule for the treatment of inflammatory bowel disease and potentially other inflammatory diseases; and WTX-712, an activated Interleukin-21(IL-21) and WTX-518, an activated IL-18 (IL-18) INDUKINE molecule for the treatment of cancer. In addition, it develops WTX-1011, a conditionally activated INDUCER T cell engager molecule that targets STEAP 1 for prostate cancer, as well as WTX-2022 that targets CDH6 for ovarian and kidney cancer. Werewolf Therapeutics, Inc. was incorporated in 2017 and is headquartered in Watertown, Massachusetts.
Long Name Werewolf Therapeutics, Inc.
Market us_market
Market Cap 48,168,936
Market State PREPRE
Max Age 86,400
Message Board Id finmb_560735713
Most Recent Quarter 1,782,777,600
Net Income To Common -34,613,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 48,086,311
Number Of Analyst Opinions 3
Open 1.0
Operating Cashflow -30,148,000
Operating Margins 0.40652
Phone 617 952 0555
Post Market Change 0.008899987
Post Market Change Percent 0.89799076
Post Market Price 1.0
Post Market Time 1,791,935,258
Previous Close 0.9818
Price Eps Current Year -1.1135955
Price Hint 4
Price To Book 2.9585075
Price To Sales Trailing12 Months 2.2937589
Profit Margins -1.6482401
Quick Ratio 2.796
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key none
Region US
Regular Market Change 0.00929999
Regular Market Change Percent 0.947239
Regular Market Day High 1.0101
Regular Market Day Low 0.97
Regular Market Day Range 0.97 - 1.0101
Regular Market Open 1.0
Regular Market Previous Close 0.9818
Regular Market Price 0.9911
Regular Market Time 1,791,921,601
Regular Market Volume 353,193
Return On Assets -0.27387
Return On Equity -1.19859
Revenue Per Share 0.439
Sand P52 Week Change 0.17502642
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 48,601,487
Shares Percent Shares Out 0.0517
Shares Short 2,511,400
Shares Short Previous Month Date 1,788,134,400
Shares Short Prior Month 1,668,357
Short Name Werewolf Therapeutics, Inc.
Short Percent Of Float 0.0625
Short Ratio 3.03
Source Interval 15
State MA
Symbol HOWL
Target High Price 10.0
Target Low Price 4.0
Target Mean Price 7.0
Target Median Price 7.0
Total Cash 21,987,000
Total Cash Per Share 0.452
Total Debt 0
Total Revenue 21,000,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -0.73
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 0.654215
Two Hundred Day Average Change 0.33688504
Two Hundred Day Average Change Percent 0.51494545
Type Disp Equity
Volume 353,193
Website https://werewolftx.com
Zip 2,472