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Werewolf Therapeutics, Inc. (HOWL)

Healthcare | Biotechnology | Watertown, United States | NasdaqGS
0.97 USD +0.02 (2.538%) ⇧ (April 20, 2026, 4 p.m. EDT)

Short-term: ☆☆☆☆☆ | Long-term: ☆☆☆☆☆ | Dividends: ☆☆☆☆☆
Hot Take | April 18, 2026, 11:43 p.m. EDT

Despite a positive price impulse over the last two weeks, the fundamental reality for HOWL is non-existent: negative earnings, negative bankruptcy-adjusted 5-year earnings, and no business from the last 5 years. Valuations are completely negative. No long-term investment hedge can be used. Avoid.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoARIMA ✓0.160710
AutoETS0.160712
MSTL0.171105
AutoTheta0.452241

Forecast horizon: 45 days | Selected: AutoARIMA

Forecast Reliability
Score 41%
H-stat 43.45
Ljung-Box p 0.000
Jarque-Bera p 0.267
Excess Kurtosis -1.12
Attribute Value
Sector Healthcare
Debt to Equity Ratio 38.037
Market Cap 47,124,332
Forward P/E -0.98
Beta 0.54
Website https://werewolftx.com

As of April 18, 2026, 11:43 p.m. EDT: Options flow is heavily skewed bearish, with 100% of expiring volume concentrated in in-the-money 2.5 strikes for the monthly expiration of 2026-07-17, indicating strong hedge demand against any downside move between current price and 2.5. There is virtually no call volume or open interest in the ITM zone for any expiration, while OTM call activity is muted. The high IV (3.00) on the prominent put wings suggests market makers are pricing in significant downside risk.


Info Dump

Attribute Value
52 Week Change 0.1098398
Address1 200 Talcott Ave
Address2 2nd Floor
All Time High 23.99
All Time Low 0.53
Ask 0.9999
Ask Size 2
Average Analyst Rating 1.0 - Strong Buy
Average Daily Volume10 Day 236,240
Average Daily Volume3 Month 404,298
Average Volume 404,298
Average Volume10Days 236,240
Beta 0.544
Bid 0.9314
Bid Size 2
Book Value 0.51
City Watertown
Compensation As Of Epoch Date 1,767,139,200
Country United States
Crypto Tradeable 0
Currency USD
Current Price 0.9697
Current Ratio 1.621
Custom Price Alert Confidence HIGH
Date Short Interest 1,774,915,200
Day High 0.99
Day Low 0.9
Debt To Equity 38.037
Display Name Werewolf Therapeutics
Earnings Timestamp 1,774,614,600
Earnings Timestamp End 1,778,157,000
Earnings Timestamp Start 1,778,157,000
Ebitda -59,043,000
Ebitda Margins 0.0
Enterprise To Ebitda 0.008
Enterprise Value -490,666
Eps Current Year -1.08
Eps Forward -0.99
Eps Trailing Twelve Months -1.33
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 0.77864
Fifty Day Average Change 0.19106
Fifty Day Average Change Percent 0.24537657
Fifty Two Week Change Percent 10.98398
Fifty Two Week High 2.38
Fifty Two Week High Change -1.4103001
Fifty Two Week High Change Percent -0.59256303
Fifty Two Week Low 0.53
Fifty Two Week Low Change 0.4397
Fifty Two Week Low Change Percent 0.8296227
Fifty Two Week Range 0.53 - 2.38
Financial Currency USD
First Trade Date Milliseconds 1,619,789,400,000
Float Shares 41,233,427
Forward Eps -0.99
Forward P E -0.9794949
Free Cashflow -12,031,375
Full Exchange Name NasdaqGS
Gmt Off Set Milliseconds -14,400,000
Gross Margins 0.0
Gross Profits -41,729,000
Has Pre Post Market Data 1
Held Percent Insiders 0.056149997
Held Percent Institutions 0.41139
Implied Shares Outstanding 48,596,817
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Ipo Expected Date 2,021-04-30
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Werewolf Therapeutics, Inc., a biopharmaceutical company, engages in the development of therapeutics engineered to stimulate the body's immune system for the treatment of cancer and other immune-mediated conditions. The company designs conditionally activated molecules that stimulate adaptive and innate immunity for addressing the limitations of conventional proinflammatory immune therapies through its proprietary PREDATOR platform. Its lead product candidates are WTX-124, a conditionally activated Interleukin-2 INDUKINE molecule for the treatment of advanced or metastatic solid tumors; and WTX-330, a conditionally activated Interleukin-12 INDUKINE molecule for the treatment of advanced or metastatic solid tumors and lymphoma. The company is also developing JZP898, a conditionally activated interferon alpha INDUKINE molecule for the treatment of cancer; WTX-921, a conditionally activated IL-10 INDUKINE molecule for the treatment of inflammatory bowel disease and potentially other inflammatory diseases; and WTX-712, an activated Interleukin-21(IL-21) and WTX-518, an activated IL-18 (IL-18) INDUKINE molecule for the treatment of cancer. Werewolf Therapeutics, Inc. was incorporated in 2017 and is headquartered in Watertown, Massachusetts.
Long Name Werewolf Therapeutics, Inc.
Market us_market
Market Cap 47,124,332
Market State PRE
Max Age 86,400
Message Board Id finmb_560735713
Most Recent Quarter 1,767,139,200
Net Income To Common -60,822,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 47,124,333
Number Of Analyst Opinions 3
Open 0.96
Operating Cashflow -60,292,000
Operating Margins 0.0
Payout Ratio 0.0
Phone 617 952 0555
Pre Market Change -0.01969999
Pre Market Change Percent -2.0315552
Pre Market Price 0.95
Pre Market Time 1,776,758,501
Previous Close 0.9457
Price Eps Current Year -0.8978703
Price Hint 4
Price To Book 1.9013726
Profit Margins 0.0
Quick Ratio 1.578
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.0
Region US
Regular Market Change 0.024
Regular Market Change Percent 2.5378
Regular Market Day High 0.99
Regular Market Day Low 0.9
Regular Market Day Range 0.9 - 0.99
Regular Market Open 0.96
Regular Market Previous Close 0.9457
Regular Market Price 0.9697
Regular Market Time 1,776,715,201
Regular Market Volume 302,422
Return On Assets -0.38633
Return On Equity -1.2387999
Sand P52 Week Change 0.34445214
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 48,596,817
Shares Percent Shares Out 0.028499998
Shares Short 1,383,049
Shares Short Previous Month Date 1,772,150,400
Shares Short Prior Month 2,069,809
Short Name Werewolf Therapeutics, Inc.
Short Percent Of Float 0.0344
Short Ratio 3.92
Source Interval 15
State MA
Symbol HOWL
Target High Price 10.0
Target Low Price 4.0
Target Mean Price 7.0
Target Median Price 7.0
Total Cash 57,050,000
Total Cash Per Share 1.174
Total Debt 9,435,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -1.33
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 1.087145
Two Hundred Day Average Change -0.11744499
Two Hundred Day Average Change Percent -0.10803066
Type Disp Equity
Volume 302,422
Website https://werewolftx.com
Zip 2,472