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HCW Biologics Inc. (HCWB)

Healthcare | Biotechnology | Miramar, United States | NasdaqCM
3.43 USD +0.26 (8.202%) ⇧ (Aug. 28, 2026, 4 p.m. EDT)
After hours: 3.29 -0.14 (-0.140%) ⇩ (Aug. 28, 2026, 7:35 p.m. EDT)

Short-term:★☆☆☆☆Long-term:⯪☆☆☆☆Dividends:☆☆☆☆☆
Hot Take | Aug. 22, 2026, 4:13 a.m. EDT

The immediate outlook is severely clouded by a relentless multi-year price collapse and a precarious balance sheet. While the company recently secured a $4 million PIPE investment and boasts impressive gross margins, the stock has lost nearly 98% of its value over the last four years, with four consecutive years of negative annual returns. This structural deterioration suggests the market has priced out the business quality entirely, likely due to the massive debt load ($6.5M) against minimal cash reserves ($1.2M) and a current ratio of just 0.086. The recent price action shows a sharp decline from August highs, trading well below the 50-day and 200-day moving averages, indicating strong downward momentum. With no dividend history and a forward P/E that is negative due to losses, there is no safety net for investors. The high beta amplifies volatility, making this a high-risk speculative vehicle rather than an investment opportunity.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoARIMA ✓0.842439
AutoETS0.842444
MSTL0.902262
AutoTheta1.354047

Forecast horizon: 45 days | Selected: AutoARIMA

Forecast Reliability
Score 22%
H-stat 9.87
Ljung-Box p 0.000
Jarque-Bera p 0.459
Excess Kurtosis -0.87
Attribute Value
Sector Healthcare
Debt to Equity Ratio 88.337
Revenue per Share 8.534
Market Cap 6,298,591
Forward P/E -6.24
Beta 2.36
Profit Margins -83.05%
Website https://www.hcwbiologics.com

Info Dump

Attribute Value
52 Week Change -0.90124613
Address1 2,929 North Commerce Parkway
All Time High 1,866.0
All Time Low 1.5
Ask 3.9
Ask Size 2
Average Daily Volume10 Day 266,460
Average Daily Volume3 Month 143,603
Average Volume 143,603
Average Volume10Days 266,460
Beta 2.364
Bid 2.45
Bid Size 1
Book Value 4.592
City Miramar
Compensation As Of Epoch Date 1,767,139,200
Country United States
Crypto Tradeable 0
Currency USD
Current Price 3.43
Current Ratio 0.061
Custom Price Alert Confidence HIGH
Date Short Interest 1,786,665,600
Day High 3.43
Day Low 3.0
Debt To Equity 88.337
Display Name HCW Biologics
Ebitda -5,584,538
Ebitda Margins -0.83088994
Enterprise To Ebitda -2.17
Enterprise To Revenue 1.803
Enterprise Value 12,118,628
Eps Forward -0.55
Eps Trailing Twelve Months -17.93
Esg Populated 0
Exchange NCM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fax 954 842 2037
Fifty Day Average 3.87542
Fifty Day Average Change -0.44542003
Fifty Day Average Change Percent -0.114934646
Fifty Two Week Change Percent -90.12461
Fifty Two Week High 36.648
Fifty Two Week High Change -33.218
Fifty Two Week High Change Percent -0.9064069
Fifty Two Week Low 1.5
Fifty Two Week Low Change 1.9300001
Fifty Two Week Low Change Percent 1.2866668
Fifty Two Week Range 1.5 - 36.648
Financial Currency USD
First Trade Date Milliseconds 1,626,787,800,000
Float Shares 1,069,787
Forward Eps -0.55
Forward P E -6.2363634
Free Cashflow -11,661,168
Full Exchange Name NasdaqCM
Full Time Employees 35
Fullday Change 0.26
Fullday Change Percent 8.20189
Fullday Price 3.29
Gmt Off Set Milliseconds -14,400,000
Gross Margins 0.95914
Gross Profits 6,446,566
Has Pre Post Market Data 1
Held Percent Insiders 0.09722
Held Percent Institutions 0.09026
Implied Shares Outstanding 1,836,324
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Ipo Expected Date 2,021-07-20
Language en-US
Last Fiscal Year End 1,767,139,200
Last Split Date 1,782,777,600
Last Split Factor 1:6
Long Business Summary HCW Biologics Inc., a clinical-stage biopharmaceutical company, focuses on discovering and developing novel immunotherapies for chronic, low-grade inflammation, and diseases in the United States. Its lead products include HCW11-018b, a novel, tetra-valent T-Cell engager; HCW11-040, a multifunctional fusion molecule that is a combination of cytokines and pembrolizumab; and HCW9302, injectable and interleukin 2 (IL-2) fusion protein complex, which is in clinical trial in patients with alopecia areata diseases. The company also develops HCW9201, a fusion protein designed as a reagent to use in the production of natural killer (NK) cell-based therapies; HCW9206, a fusion protein designed as a reagent to use in the production of CAR-therapies for the treatment of infectious diseases; and HCW11-006, a multi-functional immune cell stimulator. It has a license agreement with Wugen Inc. to develop cell therapy-based treatments; and a license, research and co-development agreement with WY Biotech Co., Ltd. for its preclinical molecule. HCW Biologics Inc. was incorporated in 2018 and is headquartered in Miramar, Florida.
Long Name HCW Biologics Inc.
Market us_market
Market Cap 6,298,591
Market State CLOSED
Max Age 86,400
Message Board Id finmb_628452149
Most Recent Quarter 1,782,777,600
Net Income To Common -21,410,162
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 5,821,147
Number Of Analyst Opinions 1
Open 3.2
Operating Cashflow -12,136,822
Operating Margins -23.35573
Payout Ratio 0.0
Phone 954 842 2024
Post Market Change -0.1400001
Post Market Change Percent -4.0816355
Post Market Price 3.29
Post Market Time 1,787,960,115
Previous Close 3.17
Price Hint 4
Price To Book 0.7469512
Price To Sales Trailing12 Months 0.9371249
Profit Margins -0.83049005
Quick Ratio 0.041
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key none
Region US
Regular Market Change 0.26
Regular Market Change Percent 8.20189
Regular Market Day High 3.43
Regular Market Day Low 3.0
Regular Market Day Range 3.0 - 3.43
Regular Market Open 3.2
Regular Market Previous Close 3.17
Regular Market Price 3.43
Regular Market Time 1,787,947,201
Regular Market Volume 117,134
Return On Assets -0.13885
Return On Equity -1.51359
Revenue Growth 19.697
Revenue Per Share 8.534
Sand P52 Week Change 0.20504117
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 1,836,324
Shares Percent Shares Out 0.0078
Shares Short 14,348
Shares Short Previous Month Date 1,784,073,600
Shares Short Prior Month 29,960
Short Name HCW Biologics Inc.
Short Percent Of Float 0.0082
Short Ratio 0.2
Source Interval 15
State FL
Symbol HCWB
Target High Price 29.99999
Target Low Price 29.99999
Target Mean Price 29.99999
Target Median Price 29.99999
Total Cash 741,324
Total Cash Per Share 0.404
Total Debt 6,561,361
Total Revenue 6,721,186
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -17.93
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 6.161945
Two Hundred Day Average Change -2.7319448
Two Hundred Day Average Change Percent -0.44335756
Type Disp Equity
Volume 117,134
Website https://www.hcwbiologics.com
Zip 33,025