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Halozyme Therapeutics, Inc. (HALO)

Healthcare | Biotechnology | San Diego, United States | NasdaqGS
69.29 USD +2.65 (3.977%) ⇧ (April 17, 2026, 4 p.m. EDT)
After hours: 69.14 -0.15 (-0.150%) ⇩ (April 17, 2026, 7:32 p.m. EDT)

Short-term: ★★★☆☆ | Long-term: ★★★★☆ | Dividends: ☆☆☆☆☆
Hot Take | April 18, 2026, 10:57 p.m. EDT

HALO is a high-conviction multi-year buy (4/5) driven by strong upside earnings growth potential (forward P/E ~7x) and robust cash flows, supported by the upcoming Vertex deal. However, the near-term chart is fragile; the model predicts a slight bearish drift (-3%), and the dealer's inventory (options OI) is heavily weighted on downside bets for the next month. Buy on dips for the long hold, but avoid aggressive short-term momentum plays until visible support at ~60 is defended.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
MSTL ✓0.067347
AutoARIMA0.068865
AutoETS0.068865
AutoTheta0.077274

Forecast horizon: 45 days | Selected: MSTL

Forecast Reliability
Score 80%
H-stat 0.66
Ljung-Box p 0.000
Jarque-Bera p 0.167
Excess Kurtosis -0.74
Attribute Value
Sector Healthcare
Debt to Equity Ratio 4460.194
Revenue per Share 11.654
Market Cap 8,209,084,416
Trailing P/E 27.07
Forward P/E 7.07
Beta 1.03
Profit Margins 22.69%
Website https://halozyme.com

As of April 18, 2026, 10:57 p.m. EDT: Near-term options (April expiration) show extremely low liquidity with negligible OI, while the upcoming Q4 2025 earnings report has created a distinct put skew upfront. Traders are heavily positioning for downside with significant open interest at 60, 65, and 70 strikes for the front month, evidenced by high volume/IV ratios. However, medium-term calls (June and December expirations) tell a different story, with massive open interest at distant OTM strikes (100 strike in June, 50 strike in Dec), indicating a heavy hedge or leveraged bet on a long-term recovery above ~70-80. This suggests a defensive positioning for near-term volatility risk, but a bullish thesis for the 6-12 month window.


Info Dump

Attribute Value
52 Week Change 0.20946062
Address1 12,390 El Camino Real
All Time High 82.22
All Time Low 1.41
Ask 72.71
Ask Size 1
Audit Risk 4
Average Analyst Rating 2.1 - Buy
Average Daily Volume10 Day 1,357,450
Average Daily Volume3 Month 1,739,504
Average Volume 1,739,504
Average Volume10Days 1,357,450
Beta 1.031
Bid 64.55
Bid Size 1
Board Risk 1
Book Value 0.414
City San Diego
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 3
Country United States
Crypto Tradeable 0
Currency USD
Current Price 69.29
Current Ratio 4.66
Custom Price Alert Confidence HIGH
Date Short Interest 1,774,915,200
Day High 69.44
Day Low 67.205
Debt To Equity 4,460.194
Display Name Halozyme Therapeutics
Earnings Call Timestamp End 1,771,363,800
Earnings Call Timestamp Start 1,771,363,800
Earnings Timestamp 1,771,362,000
Earnings Timestamp End 1,778,011,200
Earnings Timestamp Start 1,778,011,200
Ebitda 897,843,968
Ebitda Margins 0.64287
Enterprise To Ebitda 11.374
Enterprise To Revenue 7.312
Enterprise Value 10,211,776,512
Eps Current Year 8.088
Eps Forward 9.8025
Eps Trailing Twelve Months 2.56
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fax 858 704 8311
Fifty Day Average 68.6292
Fifty Day Average Change 0.6607971
Fifty Day Average Change Percent 0.009628512
Fifty Two Week Change Percent 20.946062
Fifty Two Week High 82.22
Fifty Two Week High Change -12.93
Fifty Two Week High Change Percent -0.15726101
Fifty Two Week Low 47.5
Fifty Two Week Low Change 21.79
Fifty Two Week Low Change Percent 0.45873687
Fifty Two Week Range 47.5 - 82.22
Financial Currency USD
First Trade Date Milliseconds 1,079,447,400,000
Float Shares 116,708,191
Forward Eps 9.8025
Forward P E 7.0686054
Free Cashflow 184,829,376
Full Exchange Name NasdaqGS
Full Time Employees 423
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,775,001,600
Gross Margins 0.77785003
Gross Profits 1,086,347,008
Has Pre Post Market Data 1
Held Percent Insiders 0.01085
Held Percent Institutions 1.07402
Implied Shares Outstanding 118,474,300
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Halozyme Therapeutics, Inc., a biopharmaceutical company, researches, develops, and commercializes of proprietary enzymes and devices in the United States, Switzerland, Belgium, Japan, and internationally. The company's products are based on the patented recombinant human hyaluronidase enzyme (rHuPH20) that enables delivery of injectable biologics, such as monoclonal antibodies and other therapeutic molecules, as well as small molecules and fluids. It offers Hylenex recombinant, a formulation of rHuPH20 that facilitates subcutaneous (SC) administration to enhance the dispersion and absorption of other injected drugs in SC urography and to enhance resorption of radiopaque agents; and XYOSTED, an injection for SC administration of testosterone replacement therapy. The company also provides Herceptin (trastuzumab) under the brand name Herceptin Hylecta; and Phesgo to treat breast cancer; Mabthera SC for chronic lymphocytic leukemia treatment; Tecentriq SC for IV infusion; Ocrevus SC for multiple sclerosis; HYQVIA to treat primary immunodeficiency disorders; DARZALEX to treat amyloidosis, and smoldering and multiple myeloma; epinephrine Injection to treat allergic reactions; nivolumab and relatlimab to treat metastatic or unresectable melanoma; teriparatide injections; ARGX-113; and ARGX-117 to treat severe autoimmune diseases in multifocal motor neuropathy. It has collaborations and licensing agreements with F. Hoffmann-La Roche, Ltd. and Hoffmann-La Roche, Inc.; Takeda Pharmaceuticals International AG and Baxalta US Inc.; Pfizer Inc.; Janssen Biotech, Inc.; AbbVie, Inc.; Eli Lilly and Company; Bristol Myers Squibb Company; argenx BVBA; ViiV Healthcare; Chugai Pharmaceutical Co., Ltd.; Acumen Pharmaceuticals, Inc.; Merus N.V.; and Skye Bioscience, Inc. The company was founded in 1998 and is headquartered in San Diego, California.
Long Name Halozyme Therapeutics, Inc.
Market us_market
Market Cap 8,209,084,416
Market State CLOSED
Max Age 86,400
Message Board Id finmb_7931206
Most Recent Quarter 1,767,139,200
Net Income To Common 316,888,992
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 8,209,084,247
Number Of Analyst Opinions 9
Open 67.43
Operating Cashflow 651,558,016
Operating Margins 0.56311
Overall Risk 1
Payout Ratio 0.0
Phone 858 794 8889
Post Market Change -0.15000153
Post Market Change Percent -0.21648365
Post Market Price 69.14
Post Market Time 1,776,468,752
Previous Close 66.64
Price Eps Current Year 8.567013
Price Hint 2
Price To Book 167.36716
Price To Sales Trailing12 Months 5.8778605
Profit Margins 0.22690001
Quick Ratio 3.298
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key buy
Recommendation Mean 2.11111
Region US
Regular Market Change 2.65
Regular Market Change Percent 3.97659
Regular Market Day High 69.44
Regular Market Day Low 67.205
Regular Market Day Range 67.205 - 69.44
Regular Market Open 67.43
Regular Market Previous Close 66.64
Regular Market Price 69.29
Regular Market Time 1,776,456,001
Regular Market Volume 1,674,195
Return On Assets 0.22236
Return On Equity 1.53593
Revenue Growth 0.516
Revenue Per Share 11.654
Sand P52 Week Change 0.38150132
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 3
Shares Outstanding 118,474,300
Shares Percent Shares Out 0.118599996
Shares Short 14,046,350
Shares Short Previous Month Date 1,772,150,400
Shares Short Prior Month 13,498,344
Short Name Halozyme Therapeutics, Inc.
Short Percent Of Float 0.1534
Short Ratio 9.45
Source Interval 15
State CA
Symbol HALO
Target High Price 96.0
Target Low Price 57.0
Target Mean Price 85.0
Target Median Price 90.0
Total Cash 142,820,000
Total Cash Per Share 1.21
Total Debt 2,177,199,104
Total Revenue 1,396,610,944
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps 2.56
Trailing P E 27.066408
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 67.99365
Two Hundred Day Average Change 1.2963486
Two Hundred Day Average Change Percent 0.019065728
Type Disp Equity
Volume 1,674,195
Website https://halozyme.com
Zip 92,130