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Gyre Therapeutics, Inc. (GYRE)

Healthcare | Biotechnology | San Diego, United States | NasdaqCM
6.34 USD -0.18 (-2.761%) ⇩ (July 13, 2026, 4 p.m. EDT)
After hours: 6.35 +0.01 (0.158%) ⇧ (July 13, 2026, 7:25 p.m. EDT)

Short-term:★★⯪☆☆Long-term:★☆☆☆☆Dividends:☆☆☆☆☆
Hot Take | July 11, 2026, 2:36 a.m. EDT

Gyre Therapeutics presents a stark dichotomy between its pristine balance sheet and its catastrophic long-term performance. Fundamentally, the company is a fortress: it holds nearly $50 million in cash against negligible debt, boasts a massive 4.6x current ratio, and maintains industry-leading gross margins of 95%. This financial health is undeniable. However, the market has overwhelmingly rejected this business, evidenced by a 97% cumulative decline over the last nine years and a trailing twelve-month loss. The recent addition to defensive indices likely reflects this safety in assets rather than optimism for growth, as revenue growth remains stagnant at just 2%. The stock is trading at a premium multiple despite negative earnings, a classic value trap where the market prices in permanent impairment. While the balance sheet prevents bankruptcy, the lack of a credible path to profitability and the persistent multi-year downtrend suggest the core business model is failing to generate value. The options market confirms this pessimism, with traders hedging downside rather than betting on a turnaround. Until there is a clear catalyst for revenue acceleration or a profitable milestone, the risk of capital destruction outweighs the safety of the cash pile.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoARIMA ✓0.189181
AutoTheta0.206748
AutoETS0.209210
MSTL0.210793

Forecast horizon: 45 days | Selected: AutoARIMA

Forecast Reliability
Score 41%
H-stat 1.13
Ljung-Box p 0.000
Jarque-Bera p 0.176
Excess Kurtosis -0.59
Attribute Value
Sector Healthcare
Last Dividend Date 2023-01-12
Debt to Equity Ratio 0.601
Revenue per Share 1.292
Market Cap 706,839,296
Forward P/E 105.67
Beta 4.78
Profit Margins -5.44%
Website https://www.gyretx.com

As of July 11, 2026, 2:36 a.m. EDT: Speculators are positioning defensively with heavy put open interest at deep strikes ($2.50), suggesting a fear of further downside or a desire to cap losses. Conversely, call activity is sparse and concentrated at out-of-the-money strikes ($10.00), indicating limited bullish conviction. Implied volatility is extremely low for both calls and puts, reflecting a lack of active speculation and a 'wait-and-see' sentiment rather than a directional bet.


Dividend Data

Dividend History
Date Dividend Yield %
2023-01-13 3.600 92.307690
2022-09-21 21.450 286.000000
2015-08-20 896.175 59.270833
Additional Data
trailingAnnualDividendRate 0.0
trailingAnnualDividendYield 0.0
lastDividendValue 3.6
lastDividendDate 2023-01-13
dividendDate 2023-01-12

Info Dump

Attribute Value
52 Week Change -0.14323258
Address1 12,730 High Bluff Drive
Address2 Suite 250
All Time High 47,990.25
All Time Low 2.85
Ask 8.12
Ask Size 2
Audit Risk 9
Average Daily Volume10 Day 166,010
Average Daily Volume3 Month 94,734
Average Volume 94,734
Average Volume10Days 166,010
Beta 4.775
Bid 4.58
Bid Size 2
Board Risk 8
Book Value 1.109
City San Diego
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 7
Country United States
Crypto Tradeable 0
Currency USD
Current Price 6.34
Current Ratio 4.636
Custom Price Alert Confidence HIGH
Date Short Interest 1,782,777,600
Day High 6.49
Day Low 6.31
Debt To Equity 0.601
Display Name Gyre Therapeutics
Dividend Date 1,673,481,600
Earnings Timestamp 1,778,157,000
Earnings Timestamp End 1,778,157,000
Earnings Timestamp Start 1,778,157,000
Ebitda 5,073,000
Ebitda Margins 0.04334
Enterprise To Ebitda 111.569
Enterprise To Revenue 4.835
Enterprise Value 565,989,120
Eps Forward 0.06
Eps Trailing Twelve Months -0.08
Esg Populated 0
Exchange NCM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 6.5432
Fifty Day Average Change -0.20319986
Fifty Day Average Change Percent -0.03105512
Fifty Two Week Change Percent -14.323258
Fifty Two Week High 9.42
Fifty Two Week High Change -3.08
Fifty Two Week High Change Percent -0.3269639
Fifty Two Week Low 5.44
Fifty Two Week Low Change 0.9000001
Fifty Two Week Low Change Percent 0.16544119
Fifty Two Week Range 5.44 - 9.42
Financial Currency USD
First Trade Date Milliseconds 1,144,848,600,000
Float Shares 33,927,316
Forward Eps 0.06
Forward P E 105.66667
Free Cashflow 9,599,000
Full Exchange Name NasdaqCM
Full Time Employees 625
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,782,864,000
Gross Margins 0.95088
Gross Profits 111,300,000
Has Pre Post Market Data 1
Held Percent Insiders 0.86334
Held Percent Institutions 0.03751
Implied Shares Outstanding 111,488,849
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 0
Language en-US
Last Dividend Date 1,673,568,000
Last Dividend Value 3.6
Last Fiscal Year End 1,767,139,200
Last Split Date 1,698,710,400
Last Split Factor 1:15
Long Business Summary Gyre Therapeutics, Inc., a pharmaceutical company, engages in the development and commercialization of small-molecule, anti-inflammatory, and anti-fibrotic drugs targeting organ fibrosis. The company offers ETUARY (Pirfenidone), an anti-fibrotic drug approved for the treatment of idiopathic pulmonary fibrosis; and under Phase 3 trials for the treatment of pneumoconiosis. It is also involved in the development of F351 (Hydronidone), a structural derivative of ETUARY under Phase 3 trials for the treatment of chronic hepatitis B (CHB)-associated liver fibrosis; and completed Phase 1 trials for the treatment of liver fibrosis associated with metabolic dysfunction-associated steatohepatitis. In addition, the company develops F573, which is in Phase 2 clinical trials for the treatment of acute/acute-on-chronic liver failure. Further, its preclinical products include F230 for the treatment of pulmonary arterial hypertension; and F528 to treat chronic obstructive pulmonary disease. Gyre Therapeutics, Inc. was founded in 2002 and is headquartered in San Diego, California. Gyre Therapeutics, Inc. operates as a subsidiary of GNI USA, Inc.
Long Name Gyre Therapeutics, Inc.
Market us_market
Market Cap 706,839,296
Market State POSTPOST
Max Age 86,400
Message Board Id finmb_100542295
Most Recent Quarter 1,774,915,200
Net Income To Common -6,362,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 725,792,406
Number Of Analyst Opinions 3
Open 6.41
Operating Cashflow 4,319,000
Operating Margins -0.30206
Overall Risk 8
Payout Ratio 0.0
Phone 858-284-0115
Post Market Change 0.009999752
Post Market Change Percent 0.1577248
Post Market Price 6.35
Post Market Time 1,783,985,101
Previous Close 6.52
Price Hint 2
Price To Book 5.716862
Price To Sales Trailing12 Months 6.038832
Profit Margins -0.05435
Quick Ratio 3.679
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key none
Region US
Regular Market Change -0.18
Regular Market Change Percent -2.76073
Regular Market Day High 6.49
Regular Market Day Low 6.31
Regular Market Day Range 6.31 - 6.49
Regular Market Open 6.41
Regular Market Previous Close 6.52
Regular Market Price 6.34
Regular Market Time 1,783,972,801
Regular Market Volume 64,819
Return On Assets 0.01035
Return On Equity -0.030769998
Revenue Growth 0.021
Revenue Per Share 1.292
Sand P52 Week Change 0.20847368
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 7
Shares Outstanding 111,488,849
Shares Percent Shares Out 0.0164
Shares Short 1,826,634
Shares Short Previous Month Date 1,780,012,800
Shares Short Prior Month 1,672,318
Short Name Gyre Therapeutics, Inc.
Short Percent Of Float 0.0519
Short Ratio 14.73
Source Interval 15
State CA
Symbol GYRE
Target High Price 20.0
Target Low Price 18.0
Target Mean Price 18.66667
Target Median Price 18.0
Total Cash 49,808,000
Total Cash Per Share 0.545
Total Debt 823,000
Total Revenue 117,049,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -0.08
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 7.4126
Two Hundred Day Average Change -1.0725999
Two Hundred Day Average Change Percent -0.14469954
Type Disp Equity
Volume 64,819
Website https://www.gyretx.com
Zip 92,130