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Monte Rosa Therapeutics, Inc. (GLUE)

Healthcare | Biotechnology | Boston, United States | NasdaqGS
21.98 USD -1.06 (-4.601%) ⇩ (July 13, 2026, 4 p.m. EDT)

Short-term:★★⯪☆☆Long-term:★☆☆☆☆Dividends:☆☆☆☆☆
Hot Take | July 11, 2026, 2:38 a.m. EDT

The fundamental reality here is stark: Monte Rosa Therapeutics is a deep-value trap in disguise. The company is hemorrhaging cash, with revenue collapsing by 95% year-over-year and gross margins in negative territory. Despite the 'strong buy' analyst consensus, which likely stems from a single potential catalyst, the balance sheet is fragile with negative free cash flow and no earnings visibility. The stock has already punished investors severely, dropping nearly 73% over the last four years, though it recently staged a technical recovery off its lows. The short-term outlook remains murky. While the price has bounced off the $4 support level, the lack of a clear catalyst makes any rally a gamble. The options market confirms this uncertainty, with heavy betting on both sides implying a binary event is needed to drive the next leg. Without a confirmed clinical success or partnership deal, the risk of further dilution or cash burn outweighs the speculative upside. For now, the thesis is neutral-to-bearish until a definitive catalyst materializes.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
MSTL ✓0.116565
AutoETS0.121524
AutoARIMA0.121524
AutoTheta0.121837
MSTL_740.129452

Forecast horizon: 60 days | Selected: MSTL

Forecast Reliability
Score 32%
H-stat 4.11
Ljung-Box p 0.000
Jarque-Bera p 0.088
Excess Kurtosis -0.23
Attribute Value
Sector Healthcare
Debt to Equity Ratio 7.485
Revenue per Share 0.491
Market Cap 1,856,857,472
Forward P/E -12.11
Beta 1.56
Website https://www.monterosatx.com

As of July 11, 2026, 2:38 a.m. EDT: Speculators are positioning for significant volatility rather than a specific directional breakout. Call open interest is heavily skewed toward out-of-the-money strikes ($25, $30, $35), suggesting a speculative bet on a sharp rally or biotech catalyst. However, put open interest is even more aggressive, with massive concentrations at lower strikes ($15, $17.50, $20) and notably higher implied volatility than calls. This 'straddle' style positioning indicates traders expect a binary event—either a major clinical readout or a regulatory decision—that could swing the price wildly in either direction, rather than a steady grind higher.


Info Dump

Attribute Value
52 Week Change 3.380228
Address1 321 Harrison Avenue
Address2 Suite 900
All Time High 45.56
All Time Low 2.44
Ask 27.17
Ask Size 2
Audit Risk 6
Average Analyst Rating 1.3 - Strong Buy
Average Daily Volume10 Day 1,985,110
Average Daily Volume3 Month 1,151,511
Average Volume 1,151,511
Average Volume10Days 1,985,110
Beta 1.562
Bid 16.17
Bid Size 2
Board Risk 6
Book Value 6.19
City Boston
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 8
Country United States
Crypto Tradeable 0
Currency USD
Current Price 21.98
Current Ratio 9.538
Custom Price Alert Confidence HIGH
Date Short Interest 1,782,777,600
Day High 23.05
Day Low 20.925
Debt To Equity 7.485
Display Name Monte Rosa Therapeutics
Earnings Timestamp 1,778,157,000
Earnings Timestamp End 1,786,019,400
Earnings Timestamp Start 1,786,019,400
Ebitda -139,940,992
Ebitda Margins 0.0
Enterprise To Ebitda -8.787
Enterprise To Revenue 28.629
Enterprise Value 1,229,701,632
Eps Current Year -1.59143
Eps Forward -1.81429
Eps Trailing Twelve Months -1.41
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 19.7263
Fifty Day Average Change 2.2537003
Fifty Day Average Change Percent 0.11424851
Fifty Two Week Change Percent 338.0228
Fifty Two Week High 25.77
Fifty Two Week High Change -3.790001
Fifty Two Week High Change Percent -0.14707027
Fifty Two Week Low 4.12
Fifty Two Week Low Change 17.86
Fifty Two Week Low Change Percent 4.334952
Fifty Two Week Range 4.12 - 25.77
Financial Currency USD
First Trade Date Milliseconds 1,624,541,400,000
Float Shares 49,578,436
Forward Eps -1.81429
Forward P E -12.114931
Free Cashflow -61,151,752
Full Exchange Name NasdaqGS
Full Time Employees 187
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,782,864,000
Gross Margins -2.3853998
Gross Profits -102,460,000
Has Pre Post Market Data 1
Held Percent Insiders 0.0057800002
Held Percent Institutions 1.1322
Implied Shares Outstanding 84,479,418
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Ipo Expected Date 2,021-06-24
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Monte Rosa Therapeutics, Inc., a clinical-stage biotechnology company, engages in the development of novel small molecule precision medicines that employ the body's natural mechanisms to selectively degrade therapeutically relevant proteins. The company develops orally bioavailable molecular glue degraders (MGDs), such as MRT-2359 for the treatment of MYC-driven tumors; MRT-6160 for the treatment of neurologic and systemic autoimmune and inflammatory diseases; and MRT-8102 for the treatment of inflammatory diseases driven by IL-1a, IL-1ß and IL-18, as well as damage-associated molecular patterns. In addition, it develops CDK2 to treat multiple cancers, including ovarian, endometrial, gastric and breast. Further, its pipeline includes programs in immunology and inflammation indications, oncology, cardiovascular, metabolic, and genetic diseases. The company also develops QuEEN, a discovery engine, to enable its target-centric MGD discovery and development approach and its rational design of MGD product candidates. It has a strategic collaboration and licensing agreement with F. Hoffmann-La Roche Ltd.; and Novartis. The company was incorporated in 2019 and is headquartered in Boston, Massachusetts.
Long Name Monte Rosa Therapeutics, Inc.
Market us_market
Market Cap 1,856,857,472
Market State PRE
Max Age 86,400
Message Board Id finmb_690261281
Most Recent Quarter 1,774,915,200
Net Income To Common -130,014,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 1,856,012,813
Number Of Analyst Opinions 6
Open 22.69
Operating Cashflow -14,675,000
Operating Margins -11.884561
Overall Risk 7
Payout Ratio 0.0
Phone 617 949 2643
Pre Market Change 0.37000084
Pre Market Change Percent 1.6833524
Pre Market Price 22.35
Pre Market Time 1,784,028,911
Previous Close 23.04
Price Eps Current Year -13.811478
Price Hint 2
Price To Book 3.5508885
Price To Sales Trailing12 Months 43.229984
Profit Margins 0.0
Quick Ratio 9.444
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.25
Region US
Regular Market Change -1.06
Regular Market Change Percent -4.6007
Regular Market Day High 23.05
Regular Market Day Low 20.925
Regular Market Day Range 20.925 - 23.05
Regular Market Open 22.69
Regular Market Previous Close 23.04
Regular Market Price 21.98
Regular Market Time 1,783,972,801
Regular Market Volume 1,556,411
Return On Assets -0.16408001
Return On Equity -0.32623002
Revenue Growth -0.95
Revenue Per Share 0.491
Sand P52 Week Change 0.20847368
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 8
Shares Outstanding 84,479,418
Shares Percent Shares Out 0.2206
Shares Short 18,634,735
Shares Short Previous Month Date 1,780,012,800
Shares Short Prior Month 16,005,122
Short Name Monte Rosa Therapeutics, Inc.
Short Percent Of Float 0.2241
Short Ratio 11.61
Source Interval 15
State MA
Symbol GLUE
Target High Price 37.0
Target Low Price 29.0
Target Mean Price 33.16667
Target Median Price 33.0
Total Cash 666,220,032
Total Cash Per Share 7.886
Total Debt 39,064,000
Total Revenue 42,953,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -1.41
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 17.048325
Two Hundred Day Average Change 4.931675
Two Hundred Day Average Change Percent 0.2892762
Type Disp Equity
Volume 1,556,411
Website https://www.monterosatx.com
Zip 2,118