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GH Research PLC (GHRS)

Healthcare | Biotechnology | Dublin, Ireland | NasdaqGM
18.34 USD +0.60 (3.382%) ⇧ (April 17, 2026, 4 p.m. EDT)
After hours: 18.73 +0.39 (2.126%) ⇧ (April 17, 2026, 7:58 p.m. EDT)

Short-term: ★★☆☆☆ | Long-term: ★★★☆☆ | Dividends: ☆☆☆☆☆
Hot Take | April 11, 2026, 3:50 p.m. EDT

GH Research PLC (GHRS) is experiencing mixed signals in the short term with recent news about clinical progress and a moderate buy consensus, which could indicate some optimism. However, the stock has been volatile and is currently trading above its 50-day average, suggesting possible overbought conditions. The lack of dividend payouts and negative earnings suggest caution for long-term investors. While the options market shows some activity, it is not enough to indicate a strong directional bias. Overall, GHRS appears to be a speculative opportunity with potential for short-term gains, but it carries significant risk and should be approached with caution.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
MSTL ✓0.057709
AutoARIMA0.068726
AutoETS0.070185
AutoTheta0.083072

Forecast horizon: 45 days | Selected: MSTL

Forecast Reliability
Score 49%
H-stat 4.04
Ljung-Box p 0.000
Jarque-Bera p 0.264
Excess Kurtosis 0.23
Attribute Value
Sector Healthcare
Debt to Equity Ratio 0.183
Market Cap 1,137,619,072
Forward P/E -9.99
Beta 1.00
Website https://www.ghres.com

As of April 11, 2026, 3:50 p.m. EDT: Options speculators are showing mixed signals. For the April 17 expiration, there is a notable amount of open interest (OI) and volume on both calls and puts, especially around the 12.5 and 15.0 strike prices, indicating potential for short-term volatility. The ATM IV for calls is higher than puts, suggesting some bullish sentiment, but the overall activity is limited. For July 17, the OI and volume are lower, with more focus on the 17.5 and 20.0 strike prices. The October 16 options show higher OI on puts around the 12.5 strike, which could imply a bearish outlook for the short term. The overall options activity suggests a cautious approach with potential for short-term price movements, but not a clear directional bias.


Info Dump

Attribute Value
52 Week Change 1.0
Address1 Joshua Dawson House
Address2 Dawson Street
All Time High 30.43
All Time Low 5.05
Ask 18.48
Ask Size 1
Average Daily Volume10 Day 117,230
Average Daily Volume3 Month 196,120
Average Volume 196,120
Average Volume10Days 117,230
Beta 1.003
Bid 18.11
Bid Size 1
Book Value 4.509
City Dublin
Country Ireland
Crypto Tradeable 0
Currency USD
Current Price 18.34
Current Ratio 34.126
Custom Price Alert Confidence HIGH
Date Short Interest 1,774,915,200
Day High 18.6999
Day Low 17.64
Debt To Equity 0.183
Display Name GH Research
Earnings Timestamp 1,772,717,400
Earnings Timestamp End 1,778,157,000
Earnings Timestamp Start 1,778,157,000
Ebitda -60,599,000
Ebitda Margins 0.0
Enterprise To Ebitda -14.149
Enterprise Value 857,423,104
Eps Current Year -1.32429
Eps Forward -1.83571
Eps Trailing Twelve Months -0.79
Esg Populated 0
Exchange NGM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 15.2136
Fifty Day Average Change 3.1264
Fifty Day Average Change Percent 0.20550033
Fifty Two Week Change Percent 100.0
Fifty Two Week High 19.51
Fifty Two Week High Change -1.1700001
Fifty Two Week High Change Percent -0.05996925
Fifty Two Week Low 8.663
Fifty Two Week Low Change 9.677
Fifty Two Week Low Change Percent 1.1170495
Fifty Two Week Range 8.663 - 19.51
Financial Currency USD
First Trade Date Milliseconds 1,624,627,800,000
Float Shares 22,816,272
Forward Eps -1.83571
Forward P E -9.9906845
Free Cashflow -30,543,876
Full Exchange Name NasdaqGM
Full Time Employees 73
Gmt Off Set Milliseconds -14,400,000
Gross Margins 0.0
Has Pre Post Market Data 1
Held Percent Insiders 0.26775998
Held Percent Institutions 0.74932
Implied Shares Outstanding 62,029,395
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Ipo Expected Date 2,021-06-25
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary GH Research PLC, together with its subsidiary, operates a clinical-stage biopharmaceutical company that develops treatments for depression in the United States. The company's lead product candidate is GH001, an inhalable mebufotenin product candidate that is in Phase 2b clinical trial for treating patients with treatment-resistant depression and in Phase 2a clinical trials for treating bipolar II disorder and postpartum depression. It also develops GH002, an intravenous mebufotenin product candidate, which is in phase 1 clinical pharmacology trial in healthy volunteers focusing on psychiatric and neurological disorders. The company was founded in 2018 and is based in Dublin, Ireland.
Long Name GH Research PLC
Market us_market
Market Cap 1,137,619,072
Market State CLOSED
Max Age 86,400
Message Board Id finmb_707594028
Most Recent Quarter 1,767,139,200
Net Income To Common -48,258,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 1,132,656,752
Number Of Analyst Opinions 8
Open 17.85
Operating Cashflow -43,552,000
Operating Margins 0.0
Payout Ratio 0.0
Phone 353 1 437 8334
Post Market Change 0.3899994
Post Market Change Percent 2.126496
Post Market Price 18.73
Post Market Time 1,776,470,285
Previous Close 17.74
Price Eps Current Year -13.84893
Price Hint 2
Price To Book 4.067421
Profit Margins 0.0
Quick Ratio 33.652
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key none
Region US
Regular Market Change 0.6
Regular Market Change Percent 3.38219
Regular Market Day High 18.6999
Regular Market Day Low 17.64
Regular Market Day Range 17.64 - 18.6999
Regular Market Open 17.85
Regular Market Previous Close 17.74
Regular Market Price 18.34
Regular Market Time 1,776,456,000
Regular Market Volume 138,502
Return On Assets -0.15917
Return On Equity -0.21043
Sand P52 Week Change 0.38150132
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 62,029,395
Shares Percent Shares Out 0.0357
Shares Short 2,214,414
Shares Short Previous Month Date 1,772,150,400
Shares Short Prior Month 2,703,885
Short Name GH Research PLC
Short Percent Of Float 0.1091
Short Ratio 9.82
Source Interval 15
Symbol GHRS
Target High Price 70.0
Target Low Price 25.0
Target Mean Price 39.25
Target Median Price 36.5
Total Cash 280,708,000
Total Cash Per Share 4.525
Total Debt 512,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -0.79
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 14.409875
Two Hundred Day Average Change 3.9301252
Two Hundred Day Average Change Percent 0.27273834
Type Disp Equity
Volume 138,502
Website https://www.ghres.com
Zip D02 RY95