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GH Research PLC (GHRS)

Healthcare | Biotechnology | Dublin, Ireland | NasdaqGM
27.94 USD -0.71 (-2.478%) ⇩ (Aug. 28, 2026, 4 p.m. EDT)
After hours: 28.16 +0.22 (0.787%) ⇧ (Aug. 28, 2026, 7:52 p.m. EDT)

Short-term:★★★⯪☆Long-term:★★⯪☆☆Dividends:☆☆☆☆☆
Hot Take | Aug. 22, 2026, 5:53 a.m. EDT

The fundamental picture is mixed but leans negative due to the lack of profitability and negative free cash flow, despite a technically strong recovery over the last two years. The company has raised capital recently, which is a standard defensive move for biotech firms, yet the balance sheet remains fragile without earnings. While the long-term trajectory shows a net gain over four years, the recent price action is volatile, trading well above its 200-day average but failing to sustain momentum above the 50-day line. The options market is screaming caution; the heavy put positioning at lower strikes suggests a fear of a sharp correction, while the call buying is speculative and distant. With no dividend to cushion the blow and negative earnings, this is a high-risk speculative play rather than a core investment.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoTheta ✓0.186229
AutoARIMA0.310678
AutoETS0.321779
MSTL0.344287

Forecast horizon: 45 days | Selected: AutoTheta

Forecast Reliability
Score 39%
H-stat 1.05
Ljung-Box p 0.000
Jarque-Bera p 0.105
Excess Kurtosis -0.07
Attribute Value
Sector Healthcare
Debt to Equity Ratio 0.1
Market Cap 1,917,865,600
Forward P/E -15.10
Beta 1.29
Website https://www.ghres.com

As of Aug. 22, 2026, 5:53 a.m. EDT: Speculators are positioning for a significant downside gap, evidenced by massive open interest in October 2026 puts at the $20 strike compared to negligible call volume. Conversely, call buyers are focused on the $35 and $40 strikes, creating a distinct 'gap' in the middle where the current price sits, suggesting a binary outcome expectation rather than a linear rally.


Info Dump

Attribute Value
52 Week Change 1.0567122
Address1 Joshua Dawson House
Address2 Dawson Street
All Time High 31.439
All Time Low 5.05
Ask 36.6
Ask Size 2
Average Daily Volume10 Day 182,050
Average Daily Volume3 Month 290,316
Average Volume 290,316
Average Volume10Days 182,050
Beta 1.29
Bid 20.99
Bid Size 2
Book Value 5.237
City Dublin
Country Ireland
Crypto Tradeable 0
Currency USD
Current Price 27.94
Current Ratio 28.696
Custom Price Alert Confidence HIGH
Date Short Interest 1,786,665,600
Day High 28.61
Day Low 27.85
Debt To Equity 0.1
Display Name GH Research
Earnings Timestamp 1,786,019,400
Earnings Timestamp End 1,793,881,800
Earnings Timestamp Start 1,793,881,800
Ebitda -71,329,000
Ebitda Margins 0.0
Enterprise To Ebitda -21.808
Enterprise Value 1,555,575,552
Eps Current Year -1.17444
Eps Forward -1.85
Eps Trailing Twelve Months -0.96
Esg Populated 0
Exchange NGM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 27.6339
Fifty Day Average Change 0.30610085
Fifty Day Average Change Percent 0.011077005
Fifty Two Week Change Percent 105.67122
Fifty Two Week High 31.439
Fifty Two Week High Change -3.4989986
Fifty Two Week High Change Percent -0.11129485
Fifty Two Week Low 11.83
Fifty Two Week Low Change 16.11
Fifty Two Week Low Change Percent 1.3617921
Fifty Two Week Range 11.83 - 31.439
Financial Currency USD
First Trade Date Milliseconds 1,624,627,800,000
Float Shares 32,371,703
Forward Eps -1.85
Forward P E -15.102703
Free Cashflow -36,524,500
Full Exchange Name NasdaqGM
Full Time Employees 73
Fullday Change -0.709999
Fullday Change Percent -2.47818
Fullday Price 28.16
Gmt Off Set Milliseconds -14,400,000
Gross Margins 0.0
Has Pre Post Market Data 1
Held Percent Insiders 0.24195999
Held Percent Institutions 0.75357
Implied Shares Outstanding 68,642,287
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Ipo Expected Date 2,021-06-25
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary GH Research PLC, together with its subsidiary, operates a clinical-stage biopharmaceutical company that develops treatments for depression in the United States. The company's lead product candidate is GH001, an inhalable mebufotenin product candidate that is in Phase 2b clinical trial for treating patients with treatment-resistant depression and in Phase 2a clinical trials for treating bipolar II disorder and postpartum depression. It also develops GH002, an intravenous mebufotenin product candidate, which is in phase 1 clinical pharmacology trial in healthy volunteers focusing on psychiatric and neurological disorders. The company was founded in 2018 and is based in Dublin, Ireland.
Long Name GH Research PLC
Market us_market
Market Cap 1,917,865,600
Market State CLOSED
Max Age 86,400
Message Board Id finmb_707594028
Most Recent Quarter 1,782,777,600
Net Income To Common -62,270,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 1,967,287,945
Number Of Analyst Opinions 9
Open 28.61
Operating Cashflow -51,703,000
Operating Margins 0.0
Payout Ratio 0.0
Phone 353 1 437 8334
Post Market Change 0.21999931
Post Market Change Percent 0.7873991
Post Market Price 28.16
Post Market Time 1,787,961,133
Previous Close 28.65
Price Eps Current Year -23.790062
Price Hint 2
Price To Book 5.3351154
Profit Margins 0.0
Quick Ratio 28.215
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key none
Region US
Regular Market Change -0.709999
Regular Market Change Percent -2.47818
Regular Market Day High 28.61
Regular Market Day Low 27.85
Regular Market Day Range 27.85 - 28.61
Regular Market Open 28.61
Regular Market Previous Close 28.65
Regular Market Price 27.94
Regular Market Time 1,787,947,201
Regular Market Volume 117,626
Return On Assets -0.1302
Return On Equity -0.18794
Sand P52 Week Change 0.20504117
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 68,642,287
Shares Percent Shares Out 0.0458
Shares Short 3,144,599
Shares Short Previous Month Date 1,784,073,600
Shares Short Prior Month 1,945,918
Short Name GH Research PLC
Short Percent Of Float 0.1169
Short Ratio 8.39
Source Interval 15
Symbol GHRS
Target High Price 65.0
Target Low Price 38.0
Target Mean Price 42.88889
Target Median Price 40.0
Total Cash 362,649,984
Total Cash Per Share 5.283
Total Debt 360,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -0.96
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 19.422575
Two Hundred Day Average Change 8.517426
Two Hundred Day Average Change Percent 0.43853226
Type Disp Equity
Volume 117,626
Website https://www.ghres.com
Zip D02 RY95