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Guardant Health, Inc. (GH)

Healthcare | Diagnostics & Research | Palo Alto, United States | NasdaqGS
161.50 USD -7.02 (-4.166%) ⇩ (Aug. 28, 2026, 4 p.m. EDT)
After hours: 161.50

Short-term:★★★⯪☆Long-term:★★★★☆Dividends:☆☆☆☆☆
Hot Take | Aug. 22, 2026, 5:56 a.m. EDT

Guardant Health presents a classic high-risk, high-reward turnaround story where the business fundamentals are firing on all cylinders, even as the bottom line lags. The company is delivering explosive revenue growth of nearly 45 percent, which validates the core thesis that its diagnostic platform is gaining market share. The balance sheet is surprisingly robust for a biotech, with a current ratio above four and manageable net debt, providing a safety net during the transition to profitability. However, the stock is trading at a premium valuation with a price-to-sales ratio near twenty, reflecting the market's willingness to pay for that growth despite the negative earnings. The recent price action shows strong momentum, trading well above its two-hundred-day average, yet the proximity to the fifty-two-week high suggests some resistance ahead. Options activity reveals a distinct defensive posture among traders, with heavy put buying in longer tenors acting as insurance against a potential pullback after such a steep recovery. For the long-term investor, the trajectory is compelling given the growth and cash generation, but the short-term path remains choppy as the market digests the gap between revenue success and earnings reality.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoTheta ✓0.062378
AutoARIMA0.118938
MSTL0.142058
AutoETS0.147056

Forecast horizon: 45 days | Selected: AutoTheta

Forecast Reliability
Score 41%
H-stat 0.28
Ljung-Box p 0.000
Jarque-Bera p 0.130
Excess Kurtosis -0.46
Attribute Value
Sector Healthcare
Revenue per Share 9.142
Market Cap 21,672,681,472
Forward P/E -365.10
Beta 1.59
Profit Margins -38.33%
Website https://guardanthealth.com

As of Aug. 22, 2026, 5:56 a.m. EDT: Speculators are positioning for significant volatility with implied volatility elevated across all expirations. While near-term calls show moderate open interest, longer-dated contracts (January 2027 onwards) are dominated by out-of-the-money put open interest, suggesting a hedge against a potential correction or a bearish view on the extended path despite the recent rally. The skew indicates investors expect large swings but are primarily protecting downside exposure in the medium-to-long term.


Info Dump

Attribute Value
52 Week Change 1.5337543
Address1 3,100 Hanover Street
All Time High 181.07
All Time Low 15.81
Ask 160.91
Ask Size 1
Audit Risk 1
Average Analyst Rating 1.3 - Strong Buy
Average Daily Volume10 Day 2,240,280
Average Daily Volume3 Month 2,577,935
Average Volume 2,577,935
Average Volume10Days 2,240,280
Beta 1.586
Bid 162.67
Bid Size 1
Board Risk 7
Book Value -1.668
City Palo Alto
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 7
Country United States
Crypto Tradeable 0
Currency USD
Current Price 161.5
Current Ratio 4.026
Custom Price Alert Confidence HIGH
Date Short Interest 1,786,665,600
Day High 169.6
Day Low 160.23
Display Name Guardant Health
Earnings Call Timestamp End 1,785,443,400
Earnings Call Timestamp Start 1,785,443,400
Earnings Timestamp 1,785,441,600
Earnings Timestamp End 1,793,217,600
Earnings Timestamp Start 1,793,217,600
Ebitda -430,571,008
Ebitda Margins -0.36393002
Enterprise To Ebitda -51.829
Enterprise To Revenue 18.862
Enterprise Value 22,316,224,512
Eps Current Year -1.45499
Eps Forward -0.44235
Eps Trailing Twelve Months -3.36
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fax 888 974 4258
Fifty Day Average 156.1194
Fifty Day Average Change 5.3806
Fifty Day Average Change Percent 0.034464646
Fifty Two Week Change Percent 153.37543
Fifty Two Week High 176.58
Fifty Two Week High Change -15.080002
Fifty Two Week High Change Percent -0.085400395
Fifty Two Week Low 53.4
Fifty Two Week Low Change 108.1
Fifty Two Week Low Change Percent 2.0243444
Fifty Two Week Range 53.4 - 176.58
Financial Currency USD
First Trade Date Milliseconds 1,538,659,800,000
Float Shares 129,428,180
Forward Eps -0.44235
Forward P E -365.09552
Free Cashflow 26,607,000
Full Exchange Name NasdaqGS
Full Time Employees 2,490
Fullday Change -7.02
Fullday Change Percent -4.16568
Fullday Price 161.5
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,785,542,400
Gross Margins 0.65012
Gross Profits 769,158,016
Has Pre Post Market Data 1
Held Percent Insiders 0.03973
Held Percent Institutions 1.0095
Implied Shares Outstanding 134,196,170
Industry Diagnostics & Research
Industry Disp Diagnostics & Research
Industry Key diagnostics-research
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Guardant Health, Inc., a precision oncology company, provides blood and tissue tests, and data sets in the United States and internationally. The company offers Guardant360 CDx test, a liquid biopsy test for tumor mutation profiling; Guardant360 Liquid test, which measures 740+ genes and supports all guideline-recommended biomarkers; Guardant Reveal test, a blood test that utilizes circulating tumor DNA to detect cancer at the molecular level; and Guardant360 Tissue test, a molecular profiling test for tumor tissue that provides genomic, transcriptomic, and epigenomic insights. It also provides Shield blood test for colorectal cancer screening in adults. In addition, the company offers GuardantINFINITY test that provides insights into the complexities of tumor molecular profiles and immune response to advance cancer research and therapy development; GuardantOMNI test covers 500 genes, including genes associated with homologous recombination repair deficiency and biomarkers for immuno-oncology applications; GuardantINFORM, which provides longitudinal biological insight into tumor evolution alongside longitudinal clinical outcomes; and GuardantConnect, an integrated software-based solution designed for clinical and biopharmaceutical customers to connect patients tested with assays with actionable alterations with potentially relevant clinical studies. Further, it provides Smart Platform, which delivers multiomic insights leveraging genomic, epigenomic, and RNA-based data that are scalable from research to the clinic. Additionally, the company offers development services, including companion diagnostic development and regulatory approval, clinical study setup, monitoring and maintenance, testing development and support, technologies licensing, and kit fulfillment and delivery of Shield screening tests. It has a strategic collaboration with Nuvalent, Inc. for oncology drug development. The company was incorporated in 2011 and is headquartered in Palo Alto, California.
Long Name Guardant Health, Inc.
Market us_market
Market Cap 21,672,681,472
Market State CLOSED
Max Age 86,400
Message Board Id finmb_256906841
Most Recent Quarter 1,782,777,600
Net Income To Common -453,436,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 22,614,738,568
Number Of Analyst Opinions 24
Open 166.002
Operating Cashflow -185,187,008
Operating Margins -0.38247
Overall Risk 7
Payout Ratio 0.0
Phone 855 698 8887
Post Market Change 0.0
Post Market Change Percent 0.0
Post Market Price 161.5
Post Market Time 1,787,961,063
Previous Close 168.52
Price Eps Current Year -110.99732
Price Hint 2
Price To Book -96.82254
Price To Sales Trailing12 Months 18.318476
Profit Margins -0.38326
Quick Ratio 3.533
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.32
Region US
Regular Market Change -7.02
Regular Market Change Percent -4.16568
Regular Market Day High 169.6
Regular Market Day Low 160.23
Regular Market Day Range 160.23 - 169.6
Regular Market Open 166.002
Regular Market Previous Close 168.52
Regular Market Price 161.5
Regular Market Time 1,787,947,201
Regular Market Volume 1,820,734
Return On Assets -0.18070999
Revenue Growth 0.443
Revenue Per Share 9.142
Sand P52 Week Change 0.20504117
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 8
Shares Outstanding 134,196,170
Shares Percent Shares Out 0.0834
Shares Short 11,191,601
Shares Short Previous Month Date 1,784,073,600
Shares Short Prior Month 11,421,015
Short Name Guardant Health, Inc.
Short Percent Of Float 0.086899996
Short Ratio 5.54
Source Interval 15
State CA
Symbol GH
Target High Price 225.0
Target Low Price 105.0
Target Mean Price 194.29167
Target Median Price 195.0
Total Cash 1,053,468,992
Total Cash Per Share 7.85
Total Debt 1,697,012,992
Total Revenue 1,183,105,024
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -3.36
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 115.4246
Two Hundred Day Average Change 46.0754
Two Hundred Day Average Change Percent 0.3991818
Type Disp Equity
Volume 1,820,734
Website https://guardanthealth.com
Zip 94,304