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Guardant Health, Inc. (GH)

Healthcare | Diagnostics & Research | Palo Alto, United States | NasdaqGS
91.07 USD +0.71 (0.786%) ⇧ (April 20, 2026, 4 p.m. EDT)

Short-term: ★★☆☆☆ | Long-term: ★★☆☆☆ | Dividends: ☆☆☆☆☆
Hot Take | April 19, 2026, 12:07 a.m. EDT

Despite a 'Strong Buy' analyst consensus, the market is screaming 'caution' via HMIs and short interest, while internal model signals and price action predict a shallow downtrend. The stock is a growth story in Diagnostics that is currently failing to deliver on the profitability metrics (negative operating margins), making it a poor buy signal right now. Expect volatility with a higher probability of testing support below $80 in the immediate term.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoETS ✓0.194585
MSTL0.198368
AutoTheta0.239714
AutoARIMA0.267118

Forecast horizon: 45 days | Selected: AutoETS

Forecast Reliability
Score 46%
H-stat 7.09
Ljung-Box p 0.000
Jarque-Bera p 0.139
Excess Kurtosis -0.86
Attribute Value
Sector Healthcare
Revenue per Share 7.833
Market Cap 11,945,692,160
Forward P/E -130.91
Beta 1.65
Profit Margins -42.39%
Website https://guardanthealth.com

As of April 19, 2026, 12:07 a.m. EDT: Options data reveals a highly conflicted and trending sentiment. For the near term (April 17 exp), Put OI is heavily skewed towards OTM strikes (30, 60, 80), suggesting a 'pin risk' or protective floor play against downside. Conversely, ATM Call volume shows significant flows into 100-strike OTM calls (Volume Spike) for the April 17 expiration, indicating naked longing. The forecasting model further confirms a predicted directional downside of -2.35% over the next 45 days. Overall, speculative flow is attempting to buy near-term upside but is heavily hedged for downside or positioning for a specific bounce from elevated strike resistance, creating a high-IV bid-ask spread environment rather than a clear directional bet.


Info Dump

Attribute Value
52 Week Change 1.0792236
Address1 3,100 Hanover Street
All Time High 181.07
All Time Low 15.81
Ask 115.76
Ask Size 2
Audit Risk 1
Average Analyst Rating 1.4 - Strong Buy
Average Daily Volume10 Day 2,508,290
Average Daily Volume3 Month 2,040,042
Average Volume 2,040,042
Average Volume10Days 2,508,290
Beta 1.65
Bid 65.75
Bid Size 2
Board Risk 7
Book Value -0.76
City Palo Alto
Compensation As Of Epoch Date 1,735,603,200
Compensation Risk 6
Country United States
Crypto Tradeable 0
Currency USD
Current Price 91.07
Current Ratio 4.843
Custom Price Alert Confidence HIGH
Date Short Interest 1,774,915,200
Day High 92.99
Day Low 90.0
Display Name Guardant Health
Earnings Call Timestamp End 1,778,185,800
Earnings Call Timestamp Start 1,778,185,800
Earnings Timestamp 1,778,184,000
Earnings Timestamp End 1,778,184,000
Earnings Timestamp Start 1,778,184,000
Ebitda -396,561,984
Ebitda Margins -0.40382
Enterprise To Ebitda -31.406
Enterprise To Revenue 12.682
Enterprise Value 12,454,236,160
Eps Current Year -1.56498
Eps Forward -0.69567
Eps Trailing Twelve Months -3.32
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fax 888 974 4258
Fifty Day Average 92.4192
Fifty Day Average Change -1.3491974
Fifty Day Average Change Percent -0.01459867
Fifty Two Week Change Percent 107.92236
Fifty Two Week High 120.74
Fifty Two Week High Change -29.669998
Fifty Two Week High Change Percent -0.24573463
Fifty Two Week Low 36.36
Fifty Two Week Low Change 54.71
Fifty Two Week Low Change Percent 1.5046754
Fifty Two Week Range 36.36 - 120.74
Financial Currency USD
First Trade Date Milliseconds 1,538,659,800,000
Float Shares 125,750,478
Forward Eps -0.69567
Forward P E -130.90977
Free Cashflow -88,105,872
Full Exchange Name NasdaqGS
Full Time Employees 2,490
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,775,001,600
Gross Margins 0.6446
Gross Profits 633,014,016
Has Pre Post Market Data 1
Held Percent Insiders 0.040409997
Held Percent Institutions 1.01222
Implied Shares Outstanding 131,170,441
Industry Diagnostics & Research
Industry Disp Diagnostics & Research
Industry Key diagnostics-research
Is Earnings Date Estimate 0
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Guardant Health, Inc., a precision oncology company, provides blood and tissue tests, and data sets in the United States and internationally. The company offers Guardant360 CDx test, a liquid biopsy test for tumor mutation profiling; Guardant360 Liquid test, which measures 740+ genes and supports all guideline-recommended biomarkers; Guardant Reveal test, a blood test that utilizes circulating tumor DNA to detect cancer at the molecular level; and Guardant360 Tissue test, a molecular profiling test for tumor tissue that provides genomic, transcriptomic, and epigenomic insights. It also provides Shield blood test for colorectal cancer screening in adults. In addition, the company offers GuardantINFINITY test that provides insights into the complexities of tumor molecular profiles and immune response to advance cancer research and therapy development; GuardantOMNI test covers 500 genes, including genes associated with homologous recombination repair deficiency and biomarkers for immuno-oncology applications; GuardantINFORM, which provides longitudinal biological insight into tumor evolution alongside longitudinal clinical outcomes; and GuardantConnect, an integrated software-based solution designed for clinical and biopharmaceutical customers to connect patients tested with assays with actionable alterations with potentially relevant clinical studies. Further, it provides Smart Platform, which delivers multiomic insights leveraging genomic, epigenomic, and RNA-based data that are scalable from research to the clinic. Additionally, the company offers development services, including companion diagnostic development and regulatory approval, clinical study setup, monitoring and maintenance, testing development and support, technologies licensing, and kit fulfillment and delivery of Shield screening tests. Guardant Health, Inc. was incorporated in 2011 and is headquartered in Palo Alto, California.
Long Name Guardant Health, Inc.
Market us_market
Market Cap 11,945,692,160
Market State PRE
Max Age 86,400
Message Board Id finmb_256906841
Most Recent Quarter 1,767,139,200
Net Income To Common -416,276,992
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 11,945,692,061
Number Of Analyst Opinions 22
Open 90.45
Operating Cashflow -184,760,000
Operating Margins -0.4291
Overall Risk 6
Payout Ratio 0.0
Phone 855 698 8887
Pre Market Change 1.965004
Pre Market Change Percent 2.1576853
Pre Market Price 93.035
Pre Market Time 1,776,772,110
Previous Close 90.36
Price Eps Current Year -58.192436
Price Hint 2
Price To Book -119.82895
Price To Sales Trailing12 Months 12.164396
Profit Margins -0.4239
Quick Ratio 4.425
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.3913
Region US
Regular Market Change 0.709999
Regular Market Change Percent 0.785745
Regular Market Day High 92.99
Regular Market Day Low 90.0
Regular Market Day Range 90.0 - 92.99
Regular Market Open 90.45
Regular Market Previous Close 90.36
Regular Market Price 91.07
Regular Market Time 1,776,715,201
Regular Market Volume 2,024,311
Return On Assets -0.15585
Revenue Growth 0.394
Revenue Per Share 7.833
Sand P52 Week Change 0.34445214
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 8
Shares Outstanding 131,170,441
Shares Percent Shares Out 0.104399994
Shares Short 13,696,676
Shares Short Previous Month Date 1,772,150,400
Shares Short Prior Month 10,963,431
Short Name Guardant Health, Inc.
Short Percent Of Float 0.1093
Short Ratio 7.5
Source Interval 15
State CA
Symbol GH
Target High Price 180.0
Target Low Price 90.0
Target Mean Price 128.36365
Target Median Price 130.0
Total Cash 1,201,597,952
Total Cash Per Share 9.161
Total Debt 1,710,141,952
Total Revenue 982,020,992
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -3.32
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 81.88775
Two Hundred Day Average Change 9.182251
Two Hundred Day Average Change Percent 0.11213217
Type Disp Equity
Volume 2,024,311
Website https://guardanthealth.com
Zip 94,304