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Generate Biomedicines, Inc. (GENB)

Healthcare | Biotechnology | Somerville, United States | NasdaqGS
15.33 USD -0.44 (-2.790%) ⇩ (Aug. 28, 2026, 4 p.m. EDT)
After hours: 15.50 +0.17 (1.109%) ⇧ (Aug. 28, 2026, 7:55 p.m. EDT)

Short-term:★★⯪☆☆Long-term:★☆☆☆☆Dividends:☆☆☆☆☆
Hot Take | Aug. 22, 2026, 5:44 a.m. EDT

The immediate outlook is neutral due to a lack of clear directional momentum, despite recent price volatility that pushed the stock above its moving averages. However, the long-term investment case is severely compromised by deteriorating fundamentals: revenue has contracted by nearly 38%, operating margins are deeply negative, and the company is burning significant cash with no path to profitability indicated by forward estimates. While the balance sheet currently shows a fortress-like liquidity position with minimal debt relative to cash, this does not offset the structural decline in business quality. Furthermore, the stock carries no dividend yield, eliminating any income floor for investors. The recent news of an IPO and analyst upgrades suggests potential for a scaled AI drug developer narrative, but without positive revenue growth or earnings, this remains a speculative bet rather than a sound long-term investment.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoTheta ✓0.077908
MSTL0.098543
AutoARIMA0.098829
AutoETS0.098911

Forecast horizon: 45 days | Selected: AutoTheta

Forecast Reliability
Score 39%
H-stat 0.18
Ljung-Box p 0.000
Jarque-Bera p 0.102
Excess Kurtosis -0.95
Attribute Value
Sector Healthcare
Debt to Equity Ratio 13.733
Revenue per Share 0.323
Market Cap 1,967,642,752
Forward P/E -6.72
Website https://generatebiomedicines.com

Info Dump

Attribute Value
52 Week Change 0.21185768
Address1 101 South Street
Address2 Suite 900
All Time High 22.67
All Time Low 11.0
Ask 17.26
Ask Size 8
Average Analyst Rating 1.3 - Strong Buy
Average Daily Volume10 Day 2,074,540
Average Daily Volume3 Month 1,019,033
Average Volume 1,019,033
Average Volume10Days 2,074,540
Bid 15.36
Bid Size 1
Book Value 3.555
City Somerville
Compensation As Of Epoch Date 1,767,139,200
Country United States
Crypto Tradeable 0
Currency USD
Current Price 15.33
Current Ratio 8.303
Custom Price Alert Confidence HIGH
Date Short Interest 1,786,665,600
Day High 16.3
Day Low 14.7435
Debt To Equity 13.733
Display Name Generate Biomedicines
Earnings Timestamp 1,786,019,400
Earnings Timestamp End 1,793,881,800
Earnings Timestamp Start 1,793,881,800
Ebitda -249,548,000
Ebitda Margins 0.0
Enterprise To Ebitda -6.303
Enterprise To Revenue 59.391
Enterprise Value 1,572,855,808
Eps Current Year -2.3
Eps Forward -2.28
Eps Trailing Twelve Months -2.03
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 15.2156
Fifty Day Average Change 0.11439991
Fifty Day Average Change Percent 0.007518593
Fifty Two Week Change Percent 21.185768
Fifty Two Week High 22.67
Fifty Two Week High Change -7.34
Fifty Two Week High Change Percent -0.32377592
Fifty Two Week Low 11.0
Fifty Two Week Low Change 4.33
Fifty Two Week Low Change Percent 0.39363635
Fifty Two Week Range 11.0 - 22.67
Financial Currency USD
First Trade Date Milliseconds 1,772,202,600,000
Float Shares 60,447,580
Forward Eps -2.28
Forward P E -6.7236843
Full Exchange Name NasdaqGS
Full Time Employees 312
Fullday Change -0.440001
Fullday Change Percent -2.79011
Fullday Price 15.5
Gmt Off Set Milliseconds -14,400,000
Gross Margins 0.0
Gross Profits -213,796,992
Has Pre Post Market Data 1
Held Percent Insiders 0.14050001
Held Percent Institutions 0.77586
Implied Shares Outstanding 128,352,436
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Ipo Expected Date 2,026-02-27
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Generate Biomedicines, Inc., engaged in the field of generative biology by using machine learning for drug discovery and development through the programming of novel protein therapeutics in the United States. It uses protein-based modalities for drug development. Its product includes GB-0895, is an investigational long-acting anti-TSLP monoclonal antibody in development for severe asthma that is intended to be dosed every six months; GB-4362, an MMAE payload neutralizer monoclonal antibody; GB-5267, A MUC16 CAR-T Cell therapy. In additional, it develops Generate Platform, designed to be a therapeutic area and protein modality agnostic system integrating computational innovation with scalable biohardware to address therapeutic challenges beyond the reach of traditional technologies. Generate Biomedicines, Inc. was formerly known as Generate Biologics, Inc. and changed its name to Generate Biomedicines, Inc. in February 2020. The company was incorporated in 2018 and is based in Somerville, Massachusetts.
Long Name Generate Biomedicines, Inc.
Market us_market
Market Cap 1,967,642,752
Market State CLOSED
Max Age 86,400
Message Board Id finmb_659065371
Most Recent Quarter 1,782,777,600
Net Income To Common -268,673,984
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 2,022,834,391
Number Of Analyst Opinions 5
Open 15.75
Operating Cashflow -237,022,000
Operating Margins -11.342099
Payout Ratio 0.0
Phone (888) 469-0055
Post Market Change 0.17000008
Post Market Change Percent 1.1089373
Post Market Price 15.5
Post Market Time 1,787,961,328
Previous Close 15.77
Price Eps Current Year -6.6652174
Price Hint 2
Price To Book 4.3122363
Price To Sales Trailing12 Months 74.29833
Profit Margins 0.0
Quick Ratio 8.076
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.33333
Region US
Regular Market Change -0.440001
Regular Market Change Percent -2.79011
Regular Market Day High 16.3
Regular Market Day Low 14.7435
Regular Market Day Range 14.7435 - 16.3
Regular Market Open 15.75
Regular Market Previous Close 15.77
Regular Market Price 15.33
Regular Market Time 1,787,947,201
Regular Market Volume 2,351,824
Revenue Growth -0.377
Revenue Per Share 0.323
Sand P52 Week Change 0.20204377
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 128,352,436
Shares Percent Shares Out 0.056799997
Shares Short 7,286,295
Shares Short Previous Month Date 1,784,073,600
Shares Short Prior Month 6,985,520
Short Name Generate Biomedicines, Inc.
Short Percent Of Float 0.097399995
Short Ratio 14.88
Source Interval 15
State MA
Symbol GENB
Target High Price 30.0
Target Low Price 22.0
Target Mean Price 26.0
Target Median Price 26.0
Total Cash 457,415,008
Total Cash Per Share 3.564
Total Debt 62,628,000
Total Revenue 26,483,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -2.03
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 13.838819
Two Hundred Day Average Change 1.4911814
Two Hundred Day Average Change Percent 0.107753515
Type Disp Equity
Volume 2,351,824
Website https://generatebiomedicines.com
Zip 2,143