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Gain Therapeutics, Inc. (GANX)

Healthcare | Biotechnology | Bethesda, United States | NasdaqGM
1.41 USD -0.16 (-10.191%) ⇩ (Oct. 13, 2026, 4 p.m. EDT)
After hours: 1.47 +0.06 (4.255%) ⇧ (Oct. 13, 2026, 7:11 p.m. EDT)

Short-term:★★⯪☆☆Long-term:★★⯪☆☆Dividends:☆☆☆☆☆
Hot Take ↕ | Oct. 10, 2026, 1:16 a.m. EDT

The investment case for Gain Therapeutics is currently bifurcated between a compelling long-term narrative and a precarious short-term reality. Fundamentally, the company possesses a fortress-like balance sheet with a current ratio of 4.36 and minimal debt, providing ample runway to pursue its pipeline. The recent FDA clearance for the Parkinson's drug GT-02287, coupled with functional improvements in patients, validates the core business thesis and justifies a neutral-to-positive long-term outlook; however, the lack of historical price data prevents a definitive multi-year trajectory assessment, capping the long-term conviction at neutral. In the short term, the market is expressing deep skepticism. The stock is trading well below its 50-day and 200-day averages, indicating persistent selling pressure. More critically, the options market is screaming caution: the sheer volume of put open interest suggests investors are betting against a rally or preparing for a sharp drop, creating a heavy overhang that stifles momentum. While analysts offer a 'strong buy' rating with a mean target of $7.20, the disconnect between these lofty targets and the current price of $1.64, combined with the bearish options flow, suggests the consensus may be overly optimistic regarding the immediate path to recovery. Until the stock breaks above its moving averages and the put-heavy options structure lightens, the near-term trend remains defensive.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoETS ✓0.059742
AutoTheta0.060143
MSTL0.063575
AutoARIMA0.071889

Forecast horizon: 45 days | Selected: AutoETS

Forecast Reliability
Score 38%
H-stat 0.12
Ljung-Box p 0.000
Jarque-Bera p 0.041
Excess Kurtosis -0.33
Attribute Value
Sector Healthcare
Debt to Equity Ratio 5.401
Market Cap 61,537,504
Forward P/E -2.05
Beta 0.19
Website https://gaintherapeutics.com

As of Oct. 10, 2026, 1:16 a.m. EDT: Speculators are heavily positioned for downside protection, evidenced by massive open interest in out-of-the-money puts (over 1,000 contracts at the $2.00 strike) compared to negligible call volume. This creates a 'put wall' suggesting a fear of further decline or a specific catalyst failure. Conversely, call activity is concentrated at lower strikes ($1.00-$2.00), indicating limited bullish conviction beyond the current price level. Implied volatility is significantly elevated for puts relative to calls, reflecting asymmetric risk pricing.


Info Dump

Attribute Value
52 Week Change -0.16042781
Address1 4,800 Montgomery Lane
Address2 Suite 220
All Time High 17.93
All Time Low 0.89
Ask 2.27
Ask Size 2
Average Analyst Rating 1.2 - Strong Buy
Average Daily Volume10 Day 532,850
Average Daily Volume3 Month 463,279
Average Volume 463,279
Average Volume10Days 532,850
Beta 0.194
Bid 1.28
Bid Size 2
Book Value 0.261
City Bethesda
Compensation As Of Epoch Date 1,767,139,200
Country United States
Crypto Tradeable 0
Currency USD
Current Price 1.41
Current Ratio 4.359
Custom Price Alert Confidence HIGH
Date Short Interest 1,790,726,400
Day High 1.58
Day Low 1.4
Debt To Equity 5.401
Display Name Gain Therapeutics
Dividend Yield 0.0
Earnings Timestamp End 1,754,915,400
Earnings Timestamp Start 1,754,483,400
Ebitda -19,247,876
Ebitda Margins 0.0
Enterprise To Ebitda -2.549
Enterprise Value 49,063,232
Eps Current Year -0.505
Eps Forward -0.6875
Eps Trailing Twelve Months -0.5
Esg Populated 0
Exchange NGM
Exchange Data Delayed By 15
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 1.8204
Fifty Day Average Change -0.41040003
Fifty Day Average Change Percent -0.22544497
Fifty Two Week Change Percent -16.042782
Fifty Two Week High 4.34
Fifty Two Week High Change -2.9300003
Fifty Two Week High Change Percent -0.6751152
Fifty Two Week Low 1.4
Fifty Two Week Low Change 0.00999999
Fifty Two Week Low Change Percent 0.0071428507
Fifty Two Week Range 1.4 - 4.34
Financial Currency USD
First Trade Date Milliseconds 1,616,160,600,000
Float Shares 42,635,015
Forward Eps -0.6875
Forward P E -2.050909
Free Cashflow -11,136,962
Full Exchange Name NasdaqGM
Full Time Employees 20
Fullday Change -0.100000024
Fullday Change Percent -6.3694277
Fullday Price 1.41
Gmt Off Set Milliseconds -14,400,000
Gross Margins 0.0
Gross Profits -9,986,011
Has Pre Post Market Data 1
Held Percent Insiders 0.02234
Held Percent Institutions 0.19823
Implied Shares Outstanding 43,643,619
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Ipo Expected Date 2,021-03-18
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Gain Therapeutics, Inc., a biotechnology company, develops novel small molecule therapeutics to treat diseases across various therapeutic areas in Switzerland, Spain, the United States, and Australia. The company's drug discovery platform Magellan discovers novel allosteric binding sites in a disease; identifies proprietary small molecules that bind these sites to modulate protein function; and treats the underlying cause of the disease. Its lead drug candidate is GT-02287, which is currently in a Phase 1b study for the treatment of Parkinson's disease with or without a GBA1 mutation. The company has various small molecule drug candidates, which are in the discovery, research, and preclinical stages for the treatment of dementia with Lewy bodies, Alzheimer's disease, and Gaucher's disease, lysosomal storage disorders, metabolic disorders, and solid tumors. Gain Therapeutics, Inc. was founded in 2017 and is based in Bethesda, Maryland.
Long Name Gain Therapeutics, Inc.
Market us_market
Market Cap 61,537,504
Market State PREPRE
Max Age 86,400
Message Board Id finmb_554488027
Most Recent Quarter 1,782,777,600
Net Income To Common -20,106,256
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 80,522,477
Number Of Analyst Opinions 5
Open 1.58
Operating Cashflow -18,952,456
Operating Margins 0.0
Phone 301 500 1556
Post Market Change 0.060000062
Post Market Change Percent 4.2553234
Post Market Price 1.47
Post Market Time 1,791,933,091
Previous Close 1.57
Price Eps Current Year -2.7920792
Price Hint 4
Price To Book 5.4022985
Profit Margins 0.0
Quick Ratio 4.111
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.2
Region US
Regular Market Change -0.16
Regular Market Change Percent -10.1911
Regular Market Day High 1.58
Regular Market Day Low 1.4
Regular Market Day Range 1.4 - 1.58
Regular Market Open 1.58
Regular Market Previous Close 1.57
Regular Market Price 1.41
Regular Market Time 1,791,921,601
Regular Market Volume 789,706
Return On Assets -0.95509005
Return On Equity -2.68297
Sand P52 Week Change 0.17502642
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 43,643,619
Shares Percent Shares Out 0.07
Shares Short 3,056,188
Shares Short Previous Month Date 1,788,134,400
Shares Short Prior Month 2,795,819
Short Name Gain Therapeutics, Inc.
Short Percent Of Float 0.0716
Short Ratio 7.27
Source Interval 15
State MD
Symbol GANX
Target High Price 8.0
Target Low Price 5.0
Target Mean Price 7.2
Target Median Price 8.0
Total Cash 13,084,144
Total Cash Per Share 0.3
Total Debt 609,874
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -0.5
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 1.9643
Two Hundred Day Average Change -0.55430007
Two Hundred Day Average Change Percent -0.28218707
Type Disp Equity
Volume 789,706
Website https://gaintherapeutics.com
Zip 20,814