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Fulcrum Therapeutics, Inc. (FULC)

Healthcare | Biotechnology | Cambridge, United States | NasdaqGM
3.54 USD +0.04 (1.143%) ⇧ (July 13, 2026, 4 p.m. EDT)
After hours: 3.51 -0.03 (-0.029%) ⇩ (July 13, 2026, 7:59 p.m. EDT)

Short-term:★★☆☆☆Long-term:★☆☆☆☆Dividends:☆☆☆☆☆
Hot Take | July 11, 2026, 6:20 a.m. EDT

The investment case here is severely compromised by a toxic combination of deteriorating fundamentals and existential legal risk. The company is hemorrhaging cash with negative free cash flow and a massive hole in its balance sheet, while facing a securities fraud investigation that casts a shadow over its entire valuation. Although the stock recently rallied off a 51% drop, this appears to be a dead-cat bounce driven by capitulation rather than a genuine trend reversal, especially given the recent news of a lead drug candidate exiting development. The options market confirms this fear, with traders aggressively buying deep out-of-the-money puts to hedge against further collapse. Without a credible path to profitability or a resolution to the legal issues, this remains a high-risk speculative vehicle where the odds favor further downside.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoARIMA ✓0.383817
AutoTheta0.393582
AutoETS0.411489
MSTL0.421309

Forecast horizon: 60 days | Selected: AutoARIMA

Forecast Reliability
Score 17%
H-stat 152.56
Ljung-Box p 0.000
Jarque-Bera p 0.013
Excess Kurtosis -1.83
Attribute Value
Sector Healthcare
Debt to Equity Ratio 1.76
Market Cap 235,881,952
Forward P/E -6.10
Beta 3.00
Website https://www.fulcrumtx.com

As of July 11, 2026, 6:20 a.m. EDT: Speculators are positioning heavily for downside protection, evidenced by massive open interest in out-of-the-money puts (4.5k contracts at the $3 strike) compared to negligible call volume. While there is some speculative call activity at distant strikes ($15), the overwhelming capital allocation is defensive, suggesting a belief that the stock will struggle to recover from its lows rather than surge immediately.


Info Dump

Attribute Value
52 Week Change -0.556962
Address1 26 Landsdowne Street
All Time High 33.098
All Time Low 2.25
Ask 4.39
Ask Size 2
Audit Risk 6
Average Analyst Rating 3.3 - Hold
Average Daily Volume10 Day 2,246,010
Average Daily Volume3 Month 2,397,067
Average Volume 2,397,067
Average Volume10Days 2,246,010
Beta 2.997
Bid 2.55
Bid Size 2
Board Risk 6
Book Value 5.004
City Cambridge
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 8
Country United States
Crypto Tradeable 0
Currency USD
Current Price 3.54
Current Ratio 34.334
Custom Price Alert Confidence HIGH
Date Short Interest 1,782,777,600
Day High 3.55
Day Low 3.41
Debt To Equity 1.76
Display Name Fulcrum Therapeutics
Earnings Call Timestamp End 1,777,291,200
Earnings Call Timestamp Start 1,777,291,200
Earnings Timestamp 1,777,293,000
Earnings Timestamp End 1,777,293,000
Earnings Timestamp Start 1,777,293,000
Ebitda -85,177,000
Ebitda Margins 0.0
Enterprise To Ebitda 1.075
Enterprise Value -91,567,040
Eps Current Year -0.76097
Eps Forward -0.58057
Eps Trailing Twelve Months -1.15
Esg Populated 0
Exchange NGM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 5.0786
Fifty Day Average Change -1.5386
Fifty Day Average Change Percent -0.3029575
Fifty Two Week Change Percent -55.6962
Fifty Two Week High 15.74
Fifty Two Week High Change -12.2
Fifty Two Week High Change Percent -0.7750953
Fifty Two Week Low 2.83
Fifty Two Week Low Change 0.71000004
Fifty Two Week Low Change Percent 0.2508834
Fifty Two Week Range 2.83 - 15.74
Financial Currency USD
First Trade Date Milliseconds 1,563,456,600,000
Float Shares 36,736,283
Forward Eps -0.58057
Forward P E -6.097456
Free Cashflow -37,739,000
Full Exchange Name NasdaqGM
Full Time Employees 55
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,782,864,000
Gross Margins 0.0
Gross Profits -56,783,000
Has Pre Post Market Data 1
Held Percent Insiders 0.03832
Held Percent Institutions 1.25308
Implied Shares Outstanding 66,633,321
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 0
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Fulcrum Therapeutics, Inc., a clinical-stage biopharmaceutical company, develops small molecules to improve the lives of patients with genetically defined diseases in the areas of high unmet medical need in the United States. Its clinical-stage product candidate is pociredir, a fetal hemoglobin inducer, which is in phase 1b clinical trial for the treatment of sickle cell disease and beta-thalassemia. The company also discovers programs for the treatment of diamond-blackfan anemia, Bone Marrow Failure Syndromes, novel fetal hemoglobin inducers, fibrotic disorders. It has licensce agreement with CAMP4 which includes certain small molecule compounds, composition of matter and method of use patent rights, and know-how to research, develop, manufacture, use, and commercialize. Fulcrum Therapeutics, Inc. was Incorporated in 2015 and is headquartered in Cambridge, Massachusetts.
Long Name Fulcrum Therapeutics, Inc.
Market us_market
Market Cap 235,881,952
Market State POSTPOST
Max Age 86,400
Message Board Id finmb_376267397
Most Recent Quarter 1,774,915,200
Net Income To Common -76,116,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 232,550,290
Number Of Analyst Opinions 6
Open 3.59
Operating Cashflow -63,558,000
Operating Margins 0.0
Overall Risk 7
Payout Ratio 0.0
Phone 617 651 8851
Post Market Change -0.02850008
Post Market Change Percent -0.80508703
Post Market Price 3.5115
Post Market Time 1,783,987,181
Previous Close 3.5
Price Eps Current Year -4.6519575
Price Hint 4
Price To Book 0.707434
Profit Margins 0.0
Quick Ratio 33.971
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key hold
Recommendation Mean 3.28571
Region US
Regular Market Change 0.04
Regular Market Change Percent 1.14286
Regular Market Day High 3.55
Regular Market Day Low 3.41
Regular Market Day Range 3.41 - 3.55
Regular Market Open 3.59
Regular Market Previous Close 3.5
Regular Market Price 3.54
Regular Market Time 1,783,972,801
Regular Market Volume 1,714,447
Return On Assets -0.18355
Return On Equity -0.27098
Sand P52 Week Change 0.20847368
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 8
Shares Outstanding 66,633,321
Shares Percent Shares Out 0.0964
Shares Short 6,425,180
Shares Short Previous Month Date 1,780,012,800
Shares Short Prior Month 7,994,430
Short Name Fulcrum Therapeutics, Inc.
Short Percent Of Float 0.097600006
Short Ratio 1.21
Source Interval 15
State MA
Symbol FULC
Target High Price 18.0
Target Low Price 3.0
Target Mean Price 5.83333
Target Median Price 3.5
Total Cash 333,316,000
Total Cash Per Share 5.002
Total Debt 5,867,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -1.15
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 8.3544
Two Hundred Day Average Change -4.8143997
Two Hundred Day Average Change Percent -0.5762712
Type Disp Equity
Volume 1,714,447
Website https://www.fulcrumtx.com
Zip 2,139