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Fulcrum Therapeutics, Inc. (FULC)

Healthcare | Biotechnology | Cambridge, United States | NasdaqGM
8.29 USD +0.30 (3.755%) ⇧ (April 17, 2026, 4 p.m. EDT)
After hours: 8.29

Short-term: ★★☆☆☆ | Long-term: ★★☆☆☆ | Dividends: ☆☆☆☆☆
Hot Take | April 19, 2026, 12:21 a.m. EDT

A classic 'value trap' with speculative hedging preventing a crash but failing to capitalize on momentum. The 41.1% spike in short interest coupled with a negative 45-day forecast (-1.52%) and negative free cash flow (-$34M) indicates the market is skeptical of the short-term bullish narrative, despite Phase 1b trial success that may not have translated to enough operational cash flow to offset dilution.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
MSTL ✓0.242635
AutoETS0.254995
AutoARIMA0.254995
AutoTheta0.261437

Forecast horizon: 45 days | Selected: MSTL

Forecast Reliability
Score 42%
H-stat 19.67
Ljung-Box p 0.000
Jarque-Bera p 0.162
Excess Kurtosis -1.07
Attribute Value
Sector Healthcare
Debt to Equity Ratio 1.846
Market Cap 552,115,712
Forward P/E -5.17
Beta 3.27
Website https://www.fulcrumtx.com

As of April 19, 2026, 12:21 a.m. EDT: Options flow indicates significant put buying for downside protection, particularly at the June 18 expiration, where Volume at $6.00 is 504 with OI at 414. Conversely, Call open interest is heavily concentrated near current price levels (June 18: 4.0k OI at $8.00), suggesting speculation on range-bound recovery to the $8.00 support rather than a major expansion. The imbalance in put OI volume vs call OI implies hedging sentiment or 'pin risk' positioning around the current price, which may result in a 'pin' effect preventing lower downside but also capping upside. Long-dated (Jan 27) calls show OI at very high strikes ($27.00), indicating deep-out-of-the-money speculative bets on a massive price surge.


Info Dump

Attribute Value
52 Week Change 1.3959537
Address1 26 Landsdowne Street
All Time High 33.098
All Time Low 2.25
Ask 8.32
Ask Size 3
Audit Risk 6
Average Daily Volume10 Day 822,440
Average Daily Volume3 Month 1,035,404
Average Volume 1,035,404
Average Volume10Days 822,440
Beta 3.268
Bid 8.26
Bid Size 2
Board Risk 6
Book Value 5.242
City Cambridge
Compensation As Of Epoch Date 1,735,603,200
Compensation Risk 9
Country United States
Crypto Tradeable 0
Currency USD
Current Price 8.29
Current Ratio 27.397
Custom Price Alert Confidence HIGH
Date Short Interest 1,774,915,200
Day High 8.365
Day Low 7.88
Debt To Equity 1.846
Display Name Fulcrum Therapeutics
Earnings Call Timestamp End 1,771,938,000
Earnings Call Timestamp Start 1,771,938,000
Earnings Timestamp 1,771,939,800
Earnings Timestamp End 1,777,552,200
Earnings Timestamp Start 1,777,552,200
Ebitda -83,379,000
Ebitda Margins 0.0
Enterprise To Ebitda -2.474
Enterprise Value 206,252,736
Eps Current Year -1.29989
Eps Forward -1.60322
Eps Trailing Twelve Months -1.18
Esg Populated 0
Exchange NGM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 8.4056
Fifty Day Average Change -0.11559963
Fifty Day Average Change Percent -0.013752693
Fifty Two Week Change Percent 139.59537
Fifty Two Week High 15.74
Fifty Two Week High Change -7.45
Fifty Two Week High Change Percent -0.47331637
Fifty Two Week Low 3.17
Fifty Two Week Low Change 5.12
Fifty Two Week Low Change Percent 1.6151419
Fifty Two Week Range 3.17 - 15.74
Financial Currency USD
First Trade Date Milliseconds 1,563,456,600,000
Float Shares 43,647,779
Forward Eps -1.60322
Forward P E -5.1708436
Free Cashflow -33,922,624
Full Exchange Name NasdaqGM
Full Time Employees 55
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,775,001,600
Gross Margins 0.0
Gross Profits -56,103,000
Has Pre Post Market Data 1
Held Percent Insiders 0.03856
Held Percent Institutions 1.01584
Implied Shares Outstanding 66,600,209
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Fulcrum Therapeutics, Inc., a clinical-stage biopharmaceutical company, develops small molecules to improve the lives of patients with genetically defined diseases in the areas of high unmet medical need in the United States. Its clinical-stage product candidate is pociredir, a fetal hemoglobin inducer, which is in phase 1b clinical trial for the treatment of sickle cell disease and beta-thalassemia. The company also discovers programs for the treatment of diamond-blackfan anemia, Bone Marrow Failure Syndromes, novel fetal hemoglobin inducers, fibrotic disorders. It has licensce agreement with CAMP4 which includes certain small molecule compounds, composition of matter and method of use patent rights, and know-how to research, develop, manufacture, use, and commercialize. Fulcrum Therapeutics, Inc. was Incorporated in 2015 and is headquartered in Cambridge, Massachusetts.
Long Name Fulcrum Therapeutics, Inc.
Market us_market
Market Cap 552,115,712
Market State CLOSED
Max Age 86,400
Message Board Id finmb_376267397
Most Recent Quarter 1,767,139,200
Net Income To Common -74,880,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 552,781,734
Number Of Analyst Opinions 10
Open 8.14
Operating Cashflow -60,065,000
Operating Margins 0.0
Overall Risk 7
Payout Ratio 0.0
Phone 617 651 8851
Post Market Change 0.0
Post Market Change Percent 0.0
Post Market Price 8.29
Post Market Time 1,776,456,605
Previous Close 7.99
Price Eps Current Year -6.3774624
Price Hint 2
Price To Book 1.5814574
Profit Margins 0.0
Quick Ratio 27.083
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key none
Region US
Regular Market Change 0.3
Regular Market Change Percent 3.7547
Regular Market Day High 8.365
Regular Market Day Low 7.88
Regular Market Day Range 7.88 - 8.365
Regular Market Open 8.14
Regular Market Previous Close 7.99
Regular Market Price 8.29
Regular Market Time 1,776,456,001
Regular Market Volume 1,028,761
Return On Assets -0.169
Return On Equity -0.25296
Sand P52 Week Change 0.38150132
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 8
Shares Outstanding 66,600,209
Shares Percent Shares Out 0.104499996
Shares Short 6,962,035
Shares Short Previous Month Date 1,772,150,400
Shares Short Prior Month 4,210,945
Short Name Fulcrum Therapeutics, Inc.
Short Percent Of Float 0.1393
Short Ratio 5.04
Source Interval 15
State MA
Symbol FULC
Target High Price 25.0
Target Low Price 7.0
Target Mean Price 19.0
Target Median Price 21.5
Total Cash 352,305,984
Total Cash Per Share 5.29
Total Debt 6,443,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -1.18
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 8.84025
Two Hundred Day Average Change -0.55025005
Two Hundred Day Average Change Percent -0.062243722
Type Disp Equity
Volume 1,028,761
Website https://www.fulcrumtx.com
Zip 2,139