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Exelixis, Inc. (EXEL)

Healthcare | Biotechnology | Alameda, United States | NasdaqGS
56.04 USD -0.46 (-0.814%) ⇩ (July 13, 2026, 4 p.m. EDT)

Short-term:★★★★☆Long-term:★★★★⯪Dividends:☆☆☆☆☆
Hot Take | July 11, 2026, 2:54 a.m. EDT

The investment case here is built on a powerful convergence of explosive recent performance and pristine fundamentals. The stock has delivered a staggering +98.9% return over the last year, pushing the nine-year cumulative gain to +450%, yet the company remains undervalued relative to its growth profile with a forward P/E of just 14x and robust 41% operating margins. While the lack of a dividend is a non-issue for this high-growth biotech, the balance sheet is fortress-like with $777M in cash against minimal debt. Short-term momentum is building rapidly; the price has climbed from the $51 range to $57 over the past two weeks, supported by heavy speculative call buying targeting the $60 level. This options flow confirms that smart money is betting on further upside, likely driven by the positive clinical trial results mentioned in recent headlines. The statistical forecast model offers only a weak lean, which is typical for such volatile assets, but it does not contradict the overwhelming evidence of strength found in the fundamentals and options data. This is a high-conviction entry for investors seeking exposure to a biotech powerhouse with a proven track record of delivering.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoTheta ✓0.096664
MSTL0.112013
AutoETS0.118861
AutoARIMA0.120561

Forecast horizon: 45 days | Selected: AutoTheta

Forecast Reliability
Score 43%
H-stat 3.58
Ljung-Box p 0.000
Jarque-Bera p 0.011
Excess Kurtosis 0.27
Attribute Value
Sector Healthcare
Debt to Equity Ratio 8.758
Revenue per Share 8.915
Market Cap 14,085,939,200
Trailing P/E 18.56
Forward P/E 14.03
Beta 0.42
Profit Margins 35.08%
Website https://www.exelixis.com

As of July 11, 2026, 2:54 a.m. EDT: Speculators are aggressively positioning for upside, evidenced by massive open interest in out-of-the-money calls (e.g., 2.7k contracts at the $60 strike for July expiration) compared to negligible put volume. The call chain shows a distinct 'top OI' at strikes significantly above the current price, while the put side is nearly empty except for deep out-of-the-money hedges. Implied volatility remains moderate (~50%), suggesting the market expects continued appreciation without a looming crash event.


Info Dump

Attribute Value
52 Week Change 0.23957872
Address1 1,851 Harbor Bay Parkway
All Time High 57.57
All Time Low 1.26
Ask 58.23
Ask Size 1
Audit Risk 5
Average Analyst Rating 2.3 - Buy
Average Daily Volume10 Day 3,031,830
Average Daily Volume3 Month 2,742,468
Average Volume 2,742,468
Average Volume10Days 3,031,830
Beta 0.424
Bid 52.86
Bid Size 1
Board Risk 1
Book Value 7.63
City Alameda
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 4
Country United States
Crypto Tradeable 0
Currency USD
Current Price 56.04
Current Ratio 3.258
Custom Price Alert Confidence HIGH
Date Short Interest 1,782,777,600
Day High 56.465
Day Low 55.08
Debt To Equity 8.758
Display Name Exelixis
Earnings Call Timestamp End 1,778,014,800
Earnings Call Timestamp Start 1,778,014,800
Earnings Growth 0.436
Earnings Quarterly Growth 0.319
Earnings Timestamp 1,778,011,200
Earnings Timestamp End 1,785,873,600
Earnings Timestamp Start 1,785,873,600
Ebitda 985,841,024
Ebitda Margins 0.41501
Enterprise To Ebitda 13.672
Enterprise To Revenue 5.674
Enterprise Value 13,478,273,024
Eps Current Year 3.52636
Eps Forward 3.99455
Eps Trailing Twelve Months 3.02
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fax 650 837 8300
Fifty Day Average 51.1942
Fifty Day Average Change 4.8458023
Fifty Day Average Change Percent 0.094655305
Fifty Two Week Change Percent 23.957872
Fifty Two Week High 57.57
Fifty Two Week High Change -1.5299988
Fifty Two Week High Change Percent -0.026576322
Fifty Two Week Low 33.76
Fifty Two Week Low Change 22.280003
Fifty Two Week Low Change Percent 0.6599527
Fifty Two Week Range 33.76 - 57.57
Financial Currency USD
First Trade Date Milliseconds 955,978,200,000
Float Shares 204,464,792
Forward Eps 3.99455
Forward P E 14.029115
Free Cashflow 629,119,360
Full Exchange Name NasdaqGS
Full Time Employees 1,077
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,782,864,000
Gross Margins 0.96444
Gross Profits 2,291,013,120
Has Pre Post Market Data 1
Held Percent Insiders 0.01821
Held Percent Institutions 1.06831
Implied Shares Outstanding 251,355,083
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Ir Website http://www.exelixis.com/investors-media
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Exelixis, Inc., an oncology company, focuses on the discovery, development, and commercialization of new medicines for difficult-to-treat cancers in the United States. The company offers CABOMETYX tablets for the treatment of patients with advanced renal cell carcinoma who received prior anti-angiogenic therapy; and COMETRIQ capsules for the treatment of progressive and metastatic medullary thyroid cancer. Its CABOMETYX and COMETRIQ are derived from cabozantinib, an inhibitor of multiple tyrosine kinases, including MET, AXL, RET, and VEGF receptors. The company also offers COTELLIC, an inhibitor of MEK as a combination regimen to treat specific forms of advanced melanoma; and MINNEBRO, an oral non-steroidal selective blocker of the mineralocorticoid receptor for the treatment of hypertension in Japan. It develops zanzalintinib, a novel, potent oral inhibitor of kinases, including the TAM kinases, MET, and VEGF receptors; XL309, a small molecule inhibitor of USP1, a synthetic lethal target in the context of BRCA-mutated tumors; XB010, an antibody-drug conjugates (ADC) consisting of a MMAE payload conjugated to a monoclonal antibody targeting the tumor antigen 5T4; XB628, a first-in-class bispecific antibody that targets programmed cell death ligand 1and natural killer cell receptor group 2A; and XB371, a next-generation tissue factor targeting ADC with a topoisomerase inhibitor payload. It has research collaborations and license agreements with Ipsen Pharma SAS; Takeda Pharmaceutical Company Ltd.; F. Hoffmann-La Roche Ltd.; Catalent, Inc.; Iconic Therapeutics, Inc.; Adagene Inc.; Invenra, Inc.; Genentech, Inc.; Bristol-Myers Squibb Company; and Daiichi Sankyo Company, Limited, as well as business development activities and other collaborations. The company was formerly known as Exelixis Pharmaceuticals, Inc. and changed its name to Exelixis, Inc. in February 2000. Exelixis, Inc. was incorporated in 1994 and is headquartered in Alameda, California.
Long Name Exelixis, Inc.
Market us_market
Market Cap 14,085,939,200
Market State PRE
Max Age 86,400
Message Board Id finmb_28338
Most Recent Quarter 1,774,915,200
Net Income To Common 833,420,992
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 14,202,818,964
Number Of Analyst Opinions 16
Open 56.24
Operating Cashflow 924,675,008
Operating Margins 0.41149
Overall Risk 3
Payout Ratio 0.0
Peg Ratio 2.56
Phone 650 837 7000
Pre Market Change -0.3199997
Pre Market Change Percent -0.5710201
Pre Market Price 55.72
Pre Market Time 1,784,025,646
Previous Close 56.5
Price Eps Current Year 15.891741
Price Hint 2
Price To Book 7.344692
Price To Sales Trailing12 Months 5.9296956
Profit Margins 0.35084
Quick Ratio 3.01
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key buy
Recommendation Mean 2.26316
Region US
Regular Market Change -0.459999
Regular Market Change Percent -0.814158
Regular Market Day High 56.465
Regular Market Day Low 55.08
Regular Market Day Range 55.08 - 56.465
Regular Market Open 56.24
Regular Market Previous Close 56.5
Regular Market Price 56.04
Regular Market Time 1,783,972,801
Regular Market Volume 2,539,569
Return On Assets 0.22031
Return On Equity 0.40987
Revenue Growth 0.1
Revenue Per Share 8.915
Sand P52 Week Change 0.20847368
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 4
Shares Outstanding 251,355,083
Shares Percent Shares Out 0.11350001
Shares Short 28,539,118
Shares Short Previous Month Date 1,780,012,800
Shares Short Prior Month 29,707,071
Short Name Exelixis, Inc.
Short Percent Of Float 0.15439999
Short Ratio 10.18
Source Interval 15
State CA
Symbol EXEL
Target High Price 62.0
Target Low Price 41.0
Target Mean Price 50.9375
Target Median Price 51.0
Total Cash 777,206,976
Total Cash Per Share 3.092
Total Debt 169,540,992
Total Revenue 2,375,491,072
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps 3.02
Trailing P E 18.556292
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 44.5956
Two Hundred Day Average Change 11.444401
Two Hundred Day Average Change Percent 0.25662622
Type Disp Equity
Volume 2,539,569
Website https://www.exelixis.com
Zip 94,502