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Exelixis, Inc. (EXEL)

Healthcare | Biotechnology | Alameda, United States | NasdaqGS
54.45 USD -0.81 (-1.466%) ⇩ (Aug. 28, 2026, 4 p.m. EDT)
After hours: 54.00 -0.45 (-0.450%) ⇩ (Aug. 28, 2026, 7:30 p.m. EDT)

Short-term:★★★⯪☆Long-term:★★★★☆Dividends:☆☆☆☆☆
Hot Take | Aug. 22, 2026, 2:31 a.m. EDT

The long-term investment case remains exceptionally strong, driven by a fortress balance sheet, robust profitability, and a multi-year price trajectory that has nearly tripled over the last nine years without a recent structural decline. The company demonstrates superior capital efficiency with high returns on equity and assets, and management is generating substantial free cash flow. However, the short-term outlook faces headwinds as the stock has already rallied significantly over the past few months, creating a crowded trade that often invites a mean reversion. Options data confirms this tension, with aggressive put buying at lower strikes suggesting a high probability of a near-term pullback. While the fundamental business quality is elite, the immediate price action looks vulnerable to profit-taking.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
MSTL ✓0.036356
AutoETS0.037028
AutoARIMA0.037158
AutoTheta0.039431

Forecast horizon: 45 days | Selected: MSTL

Forecast Reliability
Score 53%
H-stat 1.12
Ljung-Box p 0.000
Jarque-Bera p 0.216
Excess Kurtosis -1.03
Attribute Value
Sector Healthcare
Debt to Equity Ratio 8.999
Revenue per Share 9.333
Market Cap 13,491,714,048
Trailing P/E 17.40
Forward P/E 13.10
Beta 0.42
Profit Margins 35.33%
Website https://www.exelixis.com

As of Aug. 22, 2026, 2:31 a.m. EDT: Speculators are positioning for a significant downside correction in the near term, evidenced by massive open interest in out-of-the-money puts (strikes 36 and 48) expiring in November and December, which dwarfs call volume. Conversely, call activity is concentrated at the money and slightly out-of-the-money, suggesting a 'long' bias that is currently being hedged by heavy put writing. The skew indicates a fear of a sharp drop below current levels despite the recent rally.


Info Dump

Attribute Value
52 Week Change 0.48628294
Address1 1,851 Harbor Bay Parkway
All Time High 57.57
All Time Low 1.26
Ask 54.46
Ask Size 1
Audit Risk 5
Average Analyst Rating 2.4 - Buy
Average Daily Volume10 Day 2,016,290
Average Daily Volume3 Month 2,587,170
Average Volume 2,587,170
Average Volume10Days 2,016,290
Beta 0.422
Bid 51.64
Bid Size 1
Board Risk 1
Book Value 7.408
City Alameda
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 4
Country United States
Crypto Tradeable 0
Currency USD
Current Price 54.45
Current Ratio 3.456
Custom Price Alert Confidence HIGH
Date Short Interest 1,786,665,600
Day High 55.25
Day Low 54.12
Debt To Equity 8.999
Display Name Exelixis
Earnings Call Timestamp End 1,785,963,600
Earnings Call Timestamp Start 1,785,963,600
Earnings Growth 0.262
Earnings Quarterly Growth 0.147
Earnings Timestamp 1,785,960,000
Earnings Timestamp End 1,793,131,200
Earnings Timestamp Start 1,793,131,200
Ebitda 1,020,321,024
Ebitda Margins 0.41886002
Enterprise To Ebitda 12.563
Enterprise To Revenue 5.262
Enterprise Value 12,818,256,896
Eps Current Year 3.57833
Eps Forward 4.15667
Eps Trailing Twelve Months 3.13
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fax 650 837 8300
Fifty Day Average 54.4554
Fifty Day Average Change -0.0053977966
Fifty Day Average Change Percent -0.00009912326
Fifty Two Week Change Percent 48.628296
Fifty Two Week High 57.57
Fifty Two Week High Change -3.119999
Fifty Two Week High Change Percent -0.054194875
Fifty Two Week Low 33.76
Fifty Two Week Low Change 20.690002
Fifty Two Week Low Change Percent 0.61285555
Fifty Two Week Range 33.76 - 57.57
Financial Currency USD
First Trade Date Milliseconds 955,978,200,000
Float Shares 213,602,685
Forward Eps 4.15667
Forward P E 13.099428
Free Cashflow 739,715,136
Full Exchange Name NasdaqGS
Full Time Employees 1,077
Fullday Change -0.809998
Fullday Change Percent -1.46579
Fullday Price 54.0
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,785,542,400
Gross Margins 0.96483004
Gross Profits 2,350,255,104
Has Pre Post Market Data 1
Held Percent Insiders 0.01845
Held Percent Institutions 1.07219
Implied Shares Outstanding 247,781,692
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Ir Website http://www.exelixis.com/investors-media
Is Earnings Date Estimate 0
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Exelixis, Inc., an oncology company, focuses on the discovery, development, and commercialization of new medicines for difficult-to-treat cancers in the United States. The company offers CABOMETYX tablets for the treatment of patients with advanced renal cell carcinoma who received prior anti-angiogenic therapy; and COMETRIQ capsules for the treatment of progressive and metastatic medullary thyroid cancer. Its CABOMETYX and COMETRIQ are derived from cabozantinib, an inhibitor of multiple tyrosine kinases, including MET, AXL, RET, and VEGF receptors. The company also offers COTELLIC, an inhibitor of MEK as a combination regimen to treat specific forms of advanced melanoma; and MINNEBRO, an oral non-steroidal selective blocker of the mineralocorticoid receptor for the treatment of hypertension in Japan. It develops zanzalintinib, a novel, potent oral inhibitor of kinases, including the TAM kinases, MET, and VEGF receptors; XL309, a small molecule inhibitor of USP1, a synthetic lethal target in the context of BRCA-mutated tumors; XB010, an antibody-drug conjugates (ADC) consisting of a MMAE payload conjugated to a monoclonal antibody targeting the tumor antigen 5T4; XB628, a first-in-class bispecific antibody that targets programmed cell death ligand 1and natural killer cell receptor group 2A; and XB371, a next-generation tissue factor targeting ADC with a topoisomerase inhibitor payload. It has research collaborations and license agreements with Ipsen Pharma SAS; Takeda Pharmaceutical Company Ltd.; F. Hoffmann-La Roche Ltd.; Catalent, Inc.; Iconic Therapeutics, Inc.; Adagene Inc.; Invenra, Inc.; Genentech, Inc.; Bristol-Myers Squibb Company; and Daiichi Sankyo Company, Limited, as well as business development activities and other collaborations. The company was formerly known as Exelixis Pharmaceuticals, Inc. and changed its name to Exelixis, Inc. in February 2000. Exelixis, Inc. was incorporated in 1994 and is headquartered in Alameda, California.
Long Name Exelixis, Inc.
Market us_market
Market Cap 13,491,714,048
Market State CLOSED
Max Age 86,400
Message Board Id finmb_28338
Most Recent Quarter 1,782,777,600
Net Income To Common 860,622,976
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 13,687,460,666
Number Of Analyst Opinions 17
Open 55.14
Operating Cashflow 1,183,422,976
Operating Margins 0.39513
Overall Risk 3
Payout Ratio 0.0
Peg Ratio 2.56
Phone 650 837 7000
Post Market Change -0.45000076
Post Market Change Percent -0.82644767
Post Market Price 54.0
Post Market Time 1,787,959,804
Previous Close 55.26
Price Eps Current Year 15.216596
Price Hint 2
Price To Book 7.350162
Price To Sales Trailing12 Months 5.5386524
Profit Margins 0.35331002
Quick Ratio 3.244
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key buy
Recommendation Mean 2.4
Region US
Regular Market Change -0.809998
Regular Market Change Percent -1.46579
Regular Market Day High 55.25
Regular Market Day Low 54.12
Regular Market Day Range 54.12 - 55.25
Regular Market Open 55.14
Regular Market Previous Close 55.26
Regular Market Price 54.45
Regular Market Time 1,787,947,201
Regular Market Volume 1,486,394
Return On Assets 0.23974001
Return On Equity 0.44393003
Revenue Growth 0.106
Revenue Per Share 9.333
Sand P52 Week Change 0.20504117
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 4
Shares Outstanding 247,781,692
Shares Percent Shares Out 0.11310001
Shares Short 28,031,459
Shares Short Previous Month Date 1,784,073,600
Shares Short Prior Month 30,913,414
Short Name Exelixis, Inc.
Short Percent Of Float 0.1546
Short Ratio 10.74
Source Interval 15
State CA
Symbol EXEL
Target High Price 66.0
Target Low Price 41.0
Target Mean Price 53.0
Target Median Price 52.0
Total Cash 839,385,024
Total Cash Per Share 3.388
Total Debt 165,928,992
Total Revenue 2,435,919,872
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps 3.13
Trailing P E 17.396166
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 47.21095
Two Hundred Day Average Change 7.239052
Two Hundred Day Average Change Percent 0.15333417
Type Disp Equity
Volume 1,486,394
Website https://www.exelixis.com
Zip 94,502