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Enanta Pharmaceuticals, Inc. (ENTA)

Healthcare | Biotechnology | Watertown, United States | NasdaqGS
13.60 USD -0.20 (-1.449%) ⇩ (Aug. 28, 2026, 4 p.m. EDT)
After hours: 13.60

Short-term:★★⯪☆☆Long-term:★☆☆☆☆Dividends:☆☆☆☆☆
Hot Take | Aug. 22, 2026, 5:56 a.m. EDT

The investment case here is fractured by a stark divergence between optimistic analyst targets and deteriorating business reality. While analysts see a path to $28, the company's fundamentals tell a different story: revenue has contracted by 21.6%, profitability is deeply negative with operating margins at -120%, and the stock has suffered a brutal 62.76% cumulative decline over the last nine years. Crucially, the price action confirms this structural deterioration, as the stock has endured three consecutive years of negative annual returns, a pattern that typically signals a failing business model rather than a temporary setback. With no dividend to provide income and a balance sheet showing negative free cash flow, the stock offers no safety margin. The recent price bounce appears to be a technical relief rally rather than a reversal of the long-term downtrend, leaving investors exposed to the risk of further value destruction.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoARIMA ✓0.029960
AutoETS0.152347
AutoTheta0.163097
MSTL0.233721

Forecast horizon: 45 days | Selected: AutoARIMA

Forecast Reliability
Score 56%
H-stat 0.82
Ljung-Box p 0.000
Jarque-Bera p 0.696
Excess Kurtosis -0.58
Attribute Value
Sector Healthcare
Debt to Equity Ratio 180.116
Revenue per Share 2.411
Market Cap 396,105,472
Forward P/E -5.38
Beta 0.93
Profit Margins -96.89%
Website https://www.enanta.com

As of Aug. 22, 2026, 5:56 a.m. EDT: Speculators are positioning for continued volatility rather than a directional breakout. Call open interest is heavily skewed out-of-the-money (OTM) at strikes like $15.00 and $17.50, suggesting bets on a rally to $20+, while put open interest concentrates at lower strikes ($10.00, $12.50), indicating a floor or hedging against further downside. The heavy OTM bias in both calls and puts implies a 'long gamma' environment where the market expects significant swings but lacks a clear consensus on which way the price will break immediately.


Info Dump

Attribute Value
52 Week Change 0.5333333
Address1 4 Kingsbury Avenue
All Time High 127.77
All Time Low 4.09
Ask 17.24
Ask Size 2
Audit Risk 5
Average Analyst Rating 1.2 - Strong Buy
Average Daily Volume10 Day 260,310
Average Daily Volume3 Month 214,720
Average Volume 214,720
Average Volume10Days 260,310
Beta 0.931
Bid 13.62
Bid Size 1
Board Risk 4
Book Value 3.471
City Watertown
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 5
Country United States
Crypto Tradeable 0
Currency USD
Current Price 13.6
Current Ratio 3.759
Custom Price Alert Confidence HIGH
Date Short Interest 1,786,665,600
Day High 13.91
Day Low 13.48
Debt To Equity 180.116
Display Name Enanta Pharmaceuticals
Earnings Call Timestamp End 1,715,027,400
Earnings Call Timestamp Start 1,715,027,400
Earnings Timestamp End 1,794,859,200
Earnings Timestamp Start 1,794,859,200
Ebitda -53,819,000
Ebitda Margins -0.82471
Enterprise To Ebitda -7.221
Enterprise To Revenue 5.955
Enterprise Value 388,639,456
Eps Current Year -2.36
Eps Forward -2.53
Eps Trailing Twelve Months -2.39
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fax 617 607 0530
Fifty Day Average 13.523
Fifty Day Average Change 0.07700062
Fifty Day Average Change Percent 0.0056940485
Fifty Two Week Change Percent 53.33333
Fifty Two Week High 17.15
Fifty Two Week High Change -3.5499992
Fifty Two Week High Change Percent -0.20699705
Fifty Two Week Low 7.05
Fifty Two Week Low Change 6.55
Fifty Two Week Low Change Percent 0.92907804
Fifty Two Week Range 7.05 - 17.15
Financial Currency USD
First Trade Date Milliseconds 1,363,872,600,000
Float Shares 22,513,062
Forward Eps -2.53
Forward P E -5.3754945
Free Cashflow -22,656,876
Full Exchange Name NasdaqGS
Full Time Employees 120
Fullday Change -0.2
Fullday Change Percent -1.44927
Fullday Price 13.6
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,785,542,400
Gross Margins 1.0
Gross Profits 65,258,000
Has Pre Post Market Data 1
Held Percent Insiders 0.04671
Held Percent Institutions 0.94332004
Implied Shares Outstanding 29,125,402
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,759,190,400
Long Business Summary Enanta Pharmaceuticals, Inc., a biotechnology company, discovers and develops small molecule drugs for virology and immunology indications. The company's product pipeline comprises EDP-514, which is in phase 1b clinical development for the treatment of chronic infection with hepatitis B virus or HBV; zelicapavir and EDP-323, which is in phase II clinical development for the treatment of respiratory syncytial virus; EDP-235, which is in phase II clinical development for the treatment of human coronaviruses; EDP-978 for chronic spontaneous urticaria (CSU); Glecaprevir, antiviral protease inhibitors for the treatment of chronic infection with hepatitis C virus or HCV; and EPS-3903 for the treatment of atopic dermatitis. It has a collaborative development and license agreement with Abbott Laboratories to develop, manufacture, and commercialize HCV NS3 and NS3/4A protease inhibitor compounds, including paritaprevir and glecaprevir. The company was incorporated in 1995 and is headquartered in Watertown, Massachusetts.
Long Name Enanta Pharmaceuticals, Inc.
Market us_market
Market Cap 396,105,472
Market State CLOSED
Max Age 86,400
Message Board Id finmb_345286
Most Recent Quarter 1,782,777,600
Net Income To Common -63,230,000
Next Fiscal Year End 1,790,726,400
Non Diluted Market Cap 401,930,547
Number Of Analyst Opinions 5
Open 13.91
Operating Cashflow -35,316,000
Operating Margins -1.2003601
Overall Risk 5
Payout Ratio 0.0
Phone 617 607 0800
Post Market Change 0.0
Post Market Change Percent 0.0
Post Market Price 13.6
Post Market Time 1,787,959,806
Previous Close 13.8
Price Eps Current Year -5.7627125
Price Hint 2
Price To Book 3.9181793
Price To Sales Trailing12 Months 6.0698376
Profit Margins -0.96892
Quick Ratio 3.619
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.2
Region US
Regular Market Change -0.2
Regular Market Change Percent -1.44927
Regular Market Day High 13.91
Regular Market Day Low 13.48
Regular Market Day Range 13.48 - 13.91
Regular Market Open 13.91
Regular Market Previous Close 13.8
Regular Market Price 13.6
Regular Market Time 1,787,947,201
Regular Market Volume 155,913
Return On Assets -0.122779995
Return On Equity -0.7012
Revenue Growth -0.216
Revenue Per Share 2.411
Sand P52 Week Change 0.20504117
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 8
Shares Outstanding 29,125,402
Shares Percent Shares Out 0.092
Shares Short 2,679,755
Shares Short Previous Month Date 1,784,073,600
Shares Short Prior Month 2,441,185
Short Name Enanta Pharmaceuticals, Inc.
Short Percent Of Float 0.1101
Short Ratio 16.74
Source Interval 15
State MA
Symbol ENTA
Target High Price 20.0
Target Low Price 19.0
Target Mean Price 19.8
Target Median Price 20.0
Total Cash 189,506,000
Total Cash Per Share 6.507
Total Debt 182,040,000
Total Revenue 65,258,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -2.39
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 13.5573
Two Hundred Day Average Change 0.042700768
Two Hundred Day Average Change Percent 0.0031496515
Type Disp Equity
Volume 155,913
Website https://www.enanta.com
Zip 2,472