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Enanta Pharmaceuticals, Inc. (ENTA)

Healthcare | Biotechnology | Watertown, United States | NasdaqGS
13.64 USD -0.06 (-0.438%) ⇩ (July 13, 2026, 4 p.m. EDT)

Short-term:★★⯪☆☆Long-term:★☆☆☆☆Dividends:☆☆☆☆☆
Hot Take | July 11, 2026, 3:16 a.m. EDT

The investment case here is fundamentally broken despite the recent price bounce. The company is in a severe multi-year structural decline, having lost over 70% of its value over the last nine years with three consecutive years of negative returns ending recently. While the stock has rallied recently—likely driven by clinical trial updates on its RSV drug—the underlying business metrics remain dire: negative earnings, negative operating cash flow, and a return on equity of nearly -59%. The market is pricing in significant distress, which is reflected in the overwhelming options activity where traders are buying deep puts rather than betting on rallies. The recent price strength appears to be a temporary relief rally against a backdrop of deteriorating fundamentals and a fortress-like balance sheet that is actually eroding due to debt obligations. Until there is clear, sustained evidence of profitability or a definitive path to cash-flow positivity, this remains a high-risk speculative vehicle rather than a viable investment.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoTheta ✓0.074337
AutoETS0.089391
AutoARIMA0.090037
MSTL0.096039
MSTL_790.129331
MSTL_1150.133132
MSTL_79_1150.165212

Forecast horizon: 60 days | Selected: AutoTheta

Forecast Reliability
Score 36%
H-stat 2.80
Ljung-Box p 0.000
Jarque-Bera p 0.180
Excess Kurtosis -0.41
Attribute Value
Sector Healthcare
Debt to Equity Ratio 160.067
Revenue per Share 2.754
Market Cap 396,629,120
Forward P/E -6.66
Beta 0.97
Profit Margins -89.55%
Website https://www.enanta.com

As of July 11, 2026, 3:16 a.m. EDT: Speculators are heavily positioning for downside protection, evidenced by massive open interest in out-of-the-money puts (strikes $7.50, $10.00, $12.50) compared to negligible call volume. The put/call ratio is skewed significantly toward hedging or bearish bets, while call activity remains thin and concentrated at strikes far above the current price, indicating a lack of immediate bullish conviction.


Info Dump

Attribute Value
52 Week Change 0.9683908
Address1 4 Kingsbury Avenue
All Time High 127.77
All Time Low 4.09
Ask 17.25
Ask Size 2
Audit Risk 5
Average Analyst Rating 1.2 - Strong Buy
Average Daily Volume10 Day 312,690
Average Daily Volume3 Month 211,665
Average Volume 211,665
Average Volume10Days 312,690
Beta 0.967
Bid 9.88
Bid Size 2
Board Risk 4
Book Value 4.012
City Watertown
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 5
Country United States
Crypto Tradeable 0
Currency USD
Current Price 13.64
Current Ratio 3.842
Custom Price Alert Confidence HIGH
Date Short Interest 1,782,777,600
Day High 13.97
Day Low 13.43
Debt To Equity 160.067
Display Name Enanta Pharmaceuticals
Earnings Call Timestamp End 1,715,027,400
Earnings Call Timestamp Start 1,715,027,400
Earnings Timestamp 1,778,529,600
Earnings Timestamp End 1,786,392,000
Earnings Timestamp Start 1,786,392,000
Ebitda -55,451,000
Ebitda Margins -0.80116
Enterprise To Ebitda -7.565
Enterprise To Revenue 6.061
Enterprise Value 419,472,096
Eps Current Year -1.88
Eps Forward -2.048
Eps Trailing Twelve Months -2.6
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fax 617 607 0530
Fifty Day Average 13.4764
Fifty Day Average Change 0.16359997
Fifty Day Average Change Percent 0.012139738
Fifty Two Week Change Percent 96.83908
Fifty Two Week High 17.15
Fifty Two Week High Change -3.5099993
Fifty Two Week High Change Percent -0.20466469
Fifty Two Week Low 6.435
Fifty Two Week Low Change 7.2050004
Fifty Two Week Low Change Percent 1.1196582
Fifty Two Week Range 6.435 - 17.15
Financial Currency USD
First Trade Date Milliseconds 1,363,872,600,000
Float Shares 20,059,139
Forward Eps -2.048
Forward P E -6.6601562
Free Cashflow 7,687,500
Full Exchange Name NasdaqGS
Full Time Employees 120
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,782,864,000
Gross Margins 1.0
Gross Profits 69,213,000
Has Pre Post Market Data 1
Held Percent Insiders 0.04684
Held Percent Institutions 0.92736
Implied Shares Outstanding 29,078,380
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,759,190,400
Long Business Summary Enanta Pharmaceuticals, Inc., a biotechnology company, discovers and develops small molecule drugs for virology and immunology indications. The company's product pipeline comprises EDP-514, which is in phase 1b clinical development for the treatment of chronic infection with hepatitis B virus or HBV; zelicapavir and EDP-323, which is in phase II clinical development for the treatment of respiratory syncytial virus; EDP-235, which is in phase II clinical development for the treatment of human coronaviruses; EDP-978 for chronic spontaneous urticaria (CSU); Glecaprevir, antiviral protease inhibitors for the treatment of chronic infection with hepatitis C virus or HCV; and EPS-3903 for the treatment of atopic dermatitis. It has a collaborative development and license agreement with Abbott Laboratories to develop, manufacture, and commercialize HCV NS3 and NS3/4A protease inhibitor compounds, including paritaprevir and glecaprevir. The company was incorporated in 1995 and is headquartered in Watertown, Massachusetts.
Long Name Enanta Pharmaceuticals, Inc.
Market us_market
Market Cap 396,629,120
Market State PRE
Max Age 86,400
Message Board Id finmb_345286
Most Recent Quarter 1,774,915,200
Net Income To Common -61,984,000
Next Fiscal Year End 1,790,726,400
Non Diluted Market Cap 396,629,103
Number Of Analyst Opinions 6
Open 13.43
Operating Cashflow -7,838,000
Operating Margins -0.69071996
Overall Risk 5
Payout Ratio 0.0
Phone 617 607 0800
Previous Close 13.7
Price Eps Current Year -7.255319
Price Hint 2
Price To Book 3.3998005
Price To Sales Trailing12 Months 5.730558
Profit Margins -0.89555
Quick Ratio 3.695
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.16667
Region US
Regular Market Change -0.0599995
Regular Market Change Percent -0.437952
Regular Market Day High 13.97
Regular Market Day Low 13.43
Regular Market Day Range 13.43 - 13.97
Regular Market Open 13.43
Regular Market Previous Close 13.7
Regular Market Price 13.64
Regular Market Time 1,783,972,801
Regular Market Volume 136,137
Return On Assets -0.118360005
Return On Equity -0.58997
Revenue Growth 0.15
Revenue Per Share 2.754
Sand P52 Week Change 0.20847368
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 8
Shares Outstanding 29,078,380
Shares Percent Shares Out 0.0888
Shares Short 2,583,579
Shares Short Previous Month Date 1,780,012,800
Shares Short Prior Month 2,274,248
Short Name Enanta Pharmaceuticals, Inc.
Short Percent Of Float 0.106400006
Short Ratio 10.17
Source Interval 15
State MA
Symbol ENTA
Target High Price 28.0
Target Low Price 19.0
Target Mean Price 21.16667
Target Median Price 20.0
Total Cash 163,774,000
Total Cash Per Share 5.632
Total Debt 186,616,992
Total Revenue 69,213,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -2.6
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 13.113525
Two Hundred Day Average Change 0.52647495
Two Hundred Day Average Change Percent 0.040147476
Type Disp Equity
Volume 136,137
Website https://www.enanta.com
Zip 2,472