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Ensysce Biosciences, Inc. (ENSC)

Healthcare | Biotechnology | La Jolla, United States | NasdaqCM
0.40 USD +0.00 (0.226%) ⇧ (Aug. 28, 2026, 4 p.m. EDT)
After hours: 0.39 -0.01 (-0.007%) ⇩ (Aug. 28, 2026, 7:30 p.m. EDT)

Short-term:★★☆☆☆Long-term:⯪☆☆☆☆Dividends:☆☆☆☆☆
Hot Take | Aug. 22, 2026, 5:30 a.m. EDT

The immediate outlook is clouded by severe technical weakness and a deteriorating business model. While the stock recently spiked nearly 50%, it remains trapped well below its 50-day moving average, indicating that the recent rally was likely a capitulation event rather than a reversal. The company is actively reviewing strategic alternatives, a stark admission that management sees limited organic growth prospects at current valuations. Fundamentally, the enterprise is in freefall: revenue has contracted by 15% year-over-year, profitability is deeply negative, and the balance sheet shows negative book value with significant cash burn. The price action confirms this structural decline, having lost virtually all its value over the past seven years with five consecutive years of negative returns. There is no dividend to provide income, and the statistical models offer no reliable guidance due to extreme volatility. This is a distressed biotech play with no clear path to recovery visible in the current data.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoETS ✓0.155874
MSTL0.177623
AutoTheta0.384967
AutoARIMA0.582307

Forecast horizon: 45 days | Selected: AutoETS

Forecast Reliability
Score 19%
H-stat 14.07
Ljung-Box p 0.000
Jarque-Bera p 0.000
Excess Kurtosis 2.73
Attribute Value
Sector Healthcare
Revenue per Share 0.679
Market Cap 7,780,771
Forward P/E -8.00
Profit Margins -280.48%
Previous Name Leisure Acquisition Corp.
Website https://www.ensysce.com

Info Dump

Attribute Value
52 Week Change -0.80817306
Address1 7,946 Ivanhoe Avenue
Address2 Suite 201
All Time High 86,364.0
All Time Low 0.23
Ask 0.5027
Ask Size 2
Average Analyst Rating 0.0 - Strong Buy
Average Daily Volume10 Day 3,146,040
Average Daily Volume3 Month 14,883,772
Average Volume 14,883,772
Average Volume10Days 3,146,040
Bid 0.286
Bid Size 2
Book Value -0.048
City La Jolla
Compensation As Of Epoch Date 1,767,139,200
Country United States
Crypto Tradeable 0
Currency USD
Current Price 0.3999
Current Ratio 0.7
Custom Price Alert Confidence HIGH
Date Short Interest 1,786,665,600
Day High 0.4119
Day Low 0.385
Display Name Ensysce Biosciences
Earnings Call Timestamp End 1,711,033,200
Earnings Call Timestamp Start 1,711,033,200
Earnings Timestamp End 1,755,201,600
Earnings Timestamp Start 1,755,201,600
Ebitda Margins 0.0
Enterprise To Revenue 1.549
Enterprise Value 6,971,774
Eps Forward -0.05
Eps Trailing Twelve Months -2.56
Esg Populated 0
Exchange NCM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 0.3227
Fifty Day Average Change 0.077199996
Fifty Day Average Change Percent 0.23923148
Fifty Two Week Change Percent -80.81731
Fifty Two Week High 2.75
Fifty Two Week High Change -2.3501
Fifty Two Week High Change Percent -0.85458183
Fifty Two Week Low 0.23
Fifty Two Week Low Change 0.16989999
Fifty Two Week Low Change Percent 0.73869556
Fifty Two Week Range 0.23 - 2.75
Financial Currency USD
First Trade Date Milliseconds 1,521,034,200,000
Float Shares 19,443,174
Forward Eps -0.05
Forward P E -7.9979997
Free Cashflow -4,498,445
Full Exchange Name NasdaqCM
Full Time Employees 8
Fullday Change 0.0009
Fullday Change Percent 0.225564
Fullday Price 0.3929
Gmt Off Set Milliseconds -14,400,000
Gross Margins -1.30559
Gross Profits -5,876,142
Has Pre Post Market Data 1
Held Percent Insiders 0.04716
Held Percent Institutions 0.0465
Implied Shares Outstanding 19,456,794
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Ipo Expected Date 2,021-07-02
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Last Split Date 1,733,443,200
Last Split Factor 1:15
Long Business Summary Ensysce Biosciences, Inc., a clinical-stage pharmaceutical company, develops prescription drugs for severe pain relief in opioid misuse, abuse, and overdose in the United States. It develops products using Trypsin Activated Abuse Protection (TAAP) platform, designed to release clinically effective drugs only when exposed to specific physiological conditions; and Multi-Pill Abuse Resistance (MPAR) platform, an over-dose protection opioid prodrug technology. The company's lead product candidate is PF614, a TAAP oxycodone prodrug candidate for the treatment of severe or chronic pain; and PF614-MPAR, a combination product of PF614 and nafamostat for overdose protection. It is also developing PF8001 and PF8026 are extended and immediate-release prodrugs of amphetamine for attention deficit hyperactivity disorder; and PF9001 to treat opioid use disorder. Ensysce Biosciences, Inc. was founded in 2003 and is based in La Jolla, California.
Long Name Ensysce Biosciences, Inc.
Market us_market
Market Cap 7,780,771
Market State CLOSED
Max Age 86,400
Message Board Id finmb_51791423
Most Recent Quarter 1,782,777,600
Name Change Date 2,026-08-28
Net Income To Common -12,623,900
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 7,846,925
Number Of Analyst Opinions 1
Open 0.4048
Operating Cashflow -8,855,395
Operating Margins -2.21279
Payout Ratio 0.0
Phone 858 263 4196
Post Market Change -0.0069999993
Post Market Change Percent -1.7504375
Post Market Price 0.3929
Post Market Time 1,787,959,805
Prev Name Leisure Acquisition Corp.
Previous Close 0.399
Price Hint 4
Price To Book -8.331249
Price To Sales Trailing12 Months 1.728771
Profit Margins -2.80484
Quick Ratio 0.269
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 0.0
Region US
Regular Market Change 0.0009
Regular Market Change Percent 0.225564
Regular Market Day High 0.4119
Regular Market Day Low 0.385
Regular Market Day Range 0.385 - 0.4119
Regular Market Open 0.4048
Regular Market Previous Close 0.399
Regular Market Price 0.3999
Regular Market Time 1,787,947,201
Regular Market Volume 486,120
Return On Assets -1.85507
Return On Equity -12.95089
Revenue Growth -0.151
Revenue Per Share 0.679
Sand P52 Week Change 0.20504117
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 19,456,794
Shares Percent Shares Out 0.0586
Shares Short 1,140,145
Shares Short Previous Month Date 1,784,073,600
Shares Short Prior Month 403,334
Short Name Ensysce Biosciences, Inc.
Short Percent Of Float 0.0586
Short Ratio 0.03
Source Interval 15
State CA
Symbol ENSC
Target High Price 8.25
Target Low Price 8.25
Target Mean Price 8.25
Target Median Price 8.25
Total Cash 676,704
Total Cash Per Share 0.035
Total Debt 196,842
Total Revenue 4,500,753
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -2.56
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 0.64747
Two Hundred Day Average Change -0.24757001
Two Hundred Day Average Change Percent -0.38236523
Type Disp Equity
Volume 486,120
Website https://www.ensysce.com
Zip 92,037