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enGene Therapeutics Inc. (ENGN)

Healthcare | Biotechnology | Montreal, Canada | NasdaqCM
1.86 USD -0.04 (-2.105%) ⇩ (July 13, 2026, 4 p.m. EDT)
After hours: 1.85 -0.01 (-0.010%) ⇩ (July 13, 2026, 7:37 p.m. EDT)

Short-term:★☆☆☆☆Long-term:★☆☆☆☆Dividends:☆☆☆☆☆
Hot Take | July 11, 2026, 6:40 a.m. EDT

The investment case for enGene Therapeutics is currently broken by a perfect storm of deteriorating clinical data, legal entanglements, and a catastrophic multi-year price collapse. While the company holds a fortress-like balance sheet with significant cash reserves relative to its debt, the business fundamentals are failing to generate value, evidenced by a 67% drop in share price over the last three years and double-digit losses in both assets and equity. The recent mixed results from the LEGEND trial have shattered the bull case, triggering a massive exodus of capital. Options markets confirm this pessimism, with traders aggressively buying deep out-of-the-money puts while ignoring calls entirely. Despite the attractive book value and low enterprise-to-EBITDA ratio, these metrics are irrelevant for a biotech firm with no earnings and a shrinking market cap; the market is correctly pricing in a high probability of further decline until a definitive positive catalyst emerges.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoTheta ✓1.419096
MSTL1.430804
AutoETS1.433823
AutoARIMA1.461019

Forecast horizon: 45 days | Selected: AutoTheta

Forecast Reliability
Score 23%
H-stat 0.98
Ljung-Box p 0.127
Jarque-Bera p 0.000
Excess Kurtosis 15.95
Attribute Value
Sector Healthcare
Debt to Equity Ratio 13.07
Market Cap 124,600,400
Forward P/E -1.32
Beta -0.28
Previous Name enGene Holdings Inc.
Website https://www.engene.com

As of July 11, 2026, 6:40 a.m. EDT: Speculators are overwhelmingly bearish, positioning heavy out-of-the-money puts at strikes of $1.00 and $2.00 across multiple expirations, while call activity is virtually nonexistent. This asymmetry suggests a strong expectation of further downside or a 'long gamma' squeeze scenario where sellers are hedging against potential volatility spikes.


Info Dump

Attribute Value
52 Week Change -0.43113774
Address1 4,868 Rue Levy
Address2 Suite 220
All Time High 47.17
All Time Low 1.4
Ask 2.35
Ask Size 2
Average Analyst Rating 2.7 - Hold
Average Daily Volume10 Day 1,282,840
Average Daily Volume3 Month 1,884,783
Average Volume 1,884,783
Average Volume10Days 1,282,840
Beta -0.275
Bid 1.36
Bid Size 2
Book Value 3.809
City Montreal
Compensation As Of Epoch Date 1,767,139,200
Country Canada
Crypto Tradeable 0
Currency USD
Current Price 1.86
Current Ratio 12.567
Custom Price Alert Confidence HIGH
Date Short Interest 1,782,777,600
Day High 1.89
Day Low 1.835
Debt To Equity 13.07
Display Name enGene Therapeutics
Earnings Timestamp 1,781,526,600
Earnings Timestamp End 1,789,389,000
Earnings Timestamp Start 1,789,389,000
Ebitda -131,911,000
Ebitda Margins 0.0
Enterprise To Ebitda 0.762
Enterprise Value -100,513,592
Eps Current Year -1.72709
Eps Forward -1.4049
Eps Trailing Twelve Months -2.18
Esg Populated 0
Exchange NCM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 2.4252
Fifty Day Average Change -0.5652
Fifty Day Average Change Percent -0.23305294
Fifty Two Week Change Percent -43.113773
Fifty Two Week High 12.25
Fifty Two Week High Change -10.39
Fifty Two Week High Change Percent -0.8481633
Fifty Two Week Low 1.4
Fifty Two Week Low Change 0.46000004
Fifty Two Week Low Change Percent 0.32857147
Fifty Two Week Range 1.4 - 12.25
Financial Currency USD
First Trade Date Milliseconds 1,643,725,800,000
Float Shares 22,487,024
Forward Eps -1.4049
Forward P E -1.3239377
Free Cashflow -69,263,752
Full Exchange Name NasdaqCM
Full Time Employees 81
Gmt Off Set Milliseconds -14,400,000
Gross Margins 0.0
Has Pre Post Market Data 1
Held Percent Insiders 0.00093000004
Held Percent Institutions 1.00301
Implied Shares Outstanding 66,989,466
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Ipo Expected Date 2,023-11-01
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,761,868,800
Long Business Summary enGene Therapeutics Inc., through its subsidiary enGene, Inc., operates as a clinical-stage biotechnology company in Canada. The company develops genetic medicines to help patients suffering from bladder cancer. Its lead product candidate is detalimogene voraplasmid, a monotherapy for the treatment of non-muscle invasive bladder cancer (NMIBC). Its pipeline includes LEGEND, which is in Phase 2. The company was formerly known as enGene Holdings Inc. and changed its name to enGene Therapeutics Inc. in April 2026. enGene Therapeutics Inc. is based in Montreal, Canada.
Long Name enGene Therapeutics Inc.
Market us_market
Market Cap 124,600,400
Market State PREPRE
Max Age 86,400
Message Board Id finmb_9516520
Most Recent Quarter 1,777,507,200
Name Change Date 2,026-07-13
Net Income To Common -126,850,000
Next Fiscal Year End 1,793,404,800
Non Diluted Market Cap 127,614,932
Number Of Analyst Opinions 7
Open 1.92
Operating Cashflow -109,997,000
Operating Margins 0.0
Payout Ratio 0.0
Phone 514 332 4888
Post Market Change -0.00999999
Post Market Change Percent -0.5376339
Post Market Price 1.85
Post Market Time 1,783,985,878
Prev Name enGene Holdings Inc.
Previous Close 1.9
Price Eps Current Year -1.076956
Price Hint 4
Price To Book 0.48831713
Profit Margins 0.0
Quick Ratio 12.166
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key hold
Recommendation Mean 2.7
Region US
Regular Market Change -0.04
Regular Market Change Percent -2.10526
Regular Market Day High 1.89
Regular Market Day Low 1.835
Regular Market Day Range 1.835 - 1.89
Regular Market Open 1.92
Regular Market Previous Close 1.9
Regular Market Price 1.86
Regular Market Time 1,783,972,801
Regular Market Volume 1,049,165
Return On Assets -0.28863
Return On Equity -0.52585
Sand P52 Week Change 0.20847368
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 66,989,466
Shares Percent Shares Out 0.017
Shares Short 1,141,694
Shares Short Previous Month Date 1,780,012,800
Shares Short Prior Month 1,622,269
Short Name enGene Therapeutics Inc.
Short Percent Of Float 0.021
Short Ratio 1.15
Source Interval 15
State QC
Symbol ENGN
Target High Price 5.0
Target Low Price 2.0
Target Mean Price 3.28571
Target Median Price 4.0
Total Cash 258,464,992
Total Cash Per Share 3.858
Total Debt 33,351,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -2.18
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 6.808425
Two Hundred Day Average Change -4.948425
Two Hundred Day Average Change Percent -0.726809
Type Disp Equity
Volume 1,049,165
Website https://www.engene.com
Zip H4R 2P1