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Precision BioSciences, Inc. (DTIL)

Healthcare | Biotechnology | Durham, United States | NasdaqCM
6.10 USD -0.43 (-6.585%) ⇩ (Oct. 13, 2026, 4 p.m. EDT)
After hours: 6.10

Short-term:★★☆☆☆Long-term:⯪☆☆☆☆Dividends:☆☆☆☆☆
Hot Take ↕ | Oct. 10, 2026, 4:14 a.m. EDT

This is a catastrophic long-term investment with a fleeting, high-risk speculative opportunity. The company has suffered a structural implosion, dropping nearly 97.5% over the last six years with four consecutive years of negative annual returns. Fundamentals are dire: the business is burning cash aggressively with negative operating margins, negative free cash flow, and a forward P/E that indicates no expected earnings. Despite a massive analyst price target of $60, this is likely a fantasy disconnected from the reality of a biotech firm with no revenue growth and a shrinking balance sheet. Short-term traders might see a bounce due to recent trial data headlines, but the options market tells a different story. Speculators are dumping calls and loading up on puts, betting on further decline rather than a recovery. The statistical forecast model offers no directional guidance, confirming the lack of a clear trend. Unless the upcoming trial results represent a paradigm-shifting breakthrough that instantly validates the entire pipeline, the odds favor continued deterioration. Avoid this as a long-term hold; it is a value trap where the low price reflects a broken business model.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoARIMA ✓0.086630
AutoETS0.086630
MSTL0.090407
AutoTheta0.120248

Forecast horizon: 45 days | Selected: AutoARIMA

Forecast Reliability
Score 39%
H-stat 1.68
Ljung-Box p 0.000
Jarque-Bera p 0.361
Excess Kurtosis -0.97
Attribute Value
Sector Healthcare
Debt to Equity Ratio 62.043
Revenue per Share 2.213
Market Cap 168,369,472
Forward P/E -3.28
Beta 1.28
Profit Margins -117.04%
Website https://precisionbiosciences.com

As of Oct. 10, 2026, 4:14 a.m. EDT: Speculators are overwhelmingly bearish, positioning heavy put volume against minimal call interest. In the near term (October/November 2026), put open interest significantly exceeds call open interest, with notable new flow into December puts. While there is some speculative call buying at $12.50 strikes for early 2027, the dominant sentiment is a bet on further downside, reinforced by the stark imbalance in volume and open interest across all expirations.


Info Dump

Attribute Value
52 Week Change 0.11623931
Address1 302 East Pettigrew St.
Address2 Suite A-100
All Time High 710.1
All Time Low 3.53
Ask 6.12
Ask Size 1
Audit Risk 3
Average Daily Volume10 Day 233,580
Average Daily Volume3 Month 274,712
Average Volume 274,712
Average Volume10Days 233,580
Beta 1.275
Bid 4.56
Bid Size 2
Board Risk 6
Book Value 1.713
City Durham
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 9
Country United States
Crypto Tradeable 0
Currency USD
Current Price 6.1
Current Ratio 12.822
Custom Price Alert Confidence HIGH
Date Short Interest 1,790,726,400
Day High 6.55
Day Low 6.05
Debt To Equity 62.043
Display Name Precision BioSciences
Dividend Yield 0.0
Earnings Timestamp 1,786,019,400
Earnings Timestamp End 1,793,622,600
Earnings Timestamp Start 1,793,622,600
Ebitda -35,148,000
Ebitda Margins -0.78011
Enterprise To Ebitda -3.099
Enterprise To Revenue 2.418
Enterprise Value 108,921,480
Eps Current Year -3.86667
Eps Forward -1.86
Eps Trailing Twelve Months -1.35
Esg Populated 0
Exchange NCM
Exchange Data Delayed By 15
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fax 480 393 5553
Fifty Day Average 7.1928
Fifty Day Average Change -1.0928001
Fifty Day Average Change Percent -0.15192972
Fifty Two Week Change Percent 11.623931
Fifty Two Week High 9.62
Fifty Two Week High Change -3.52
Fifty Two Week High Change Percent -0.36590436
Fifty Two Week Low 3.53
Fifty Two Week Low Change 2.57
Fifty Two Week Low Change Percent 0.7280453
Fifty Two Week Range 3.53 - 9.62
Financial Currency USD
First Trade Date Milliseconds 1,553,779,800,000
Float Shares 25,451,945
Forward Eps -1.86
Forward P E -3.2795699
Free Cashflow -16,252,500
Full Exchange Name NasdaqCM
Full Time Employees 67
Fullday Change -0.4300003
Fullday Change Percent -6.5849967
Fullday Price 6.1
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,790,812,800
Gross Margins 1.0
Gross Profits 45,055,000
Has Pre Post Market Data 1
Held Percent Insiders 0.080419995
Held Percent Institutions 0.68714
Implied Shares Outstanding 27,601,554
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Last Split Date 1,707,868,800
Last Split Factor 1:30
Long Business Summary Precision BioSciences, Inc., a clinical stage gene editing company, develops in vivo gene editing therapies for gene edits, including gene insertion, excision, and elimination in the United States. The company offers ARCUS, a genome editing platform for DNA genome insertion, removal, and repair. It also provides PBGENE-HBV for the treatment of chronic hepatitis B virus (HBV) to eliminate covalently closed circular DNA with direct cuts and edits, as well as to inactivate integrated HBV DNA with the goal of long-lasting reductions in hepatitis B surface antigen; and PBGENE-DMD (Excision) for the treatment of Duchenne muscular dystrophy. In addition, the company develops PBGENE-3243 for the treatment of m.3243 associated mitochondrial diseases; and iECURE-OTC (Insertion) for ornithine transcarbamylase deficiency. It has collaboration agreements with TG Cell Therapy, Inc. to develop, manufacture, and commercialize azercabtagene zapreleucel for autoimmune diseases and other indications; and iECURE, Inc., an ARCUS-mediated targeted gene insertion. Precision BioSciences, Inc. was incorporated in 2006 and is headquartered in Durham, North Carolina.
Long Name Precision BioSciences, Inc.
Market us_market
Market Cap 168,369,472
Market State POST
Max Age 86,400
Message Board Id finmb_41018856
Most Recent Quarter 1,782,777,600
Net Income To Common -53,617,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 175,545,883
Number Of Analyst Opinions 5
Open 6.51
Operating Cashflow -51,899,000
Operating Margins -0.80779
Overall Risk 7
Payout Ratio 0.0
Phone 919 314 5512
Post Market Change 0.0
Post Market Change Percent 0.0
Post Market Price 6.1
Post Market Time 1,791,921,711
Previous Close 6.53
Price Eps Current Year -1.5775849
Price Hint 2
Price To Book 3.561004
Price To Sales Trailing12 Months 3.7369764
Profit Margins -1.17039
Quick Ratio 12.262
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key none
Region US
Regular Market Change -0.43
Regular Market Change Percent -6.585
Regular Market Day High 6.55
Regular Market Day Low 6.05
Regular Market Day Range 6.05 - 6.55
Regular Market Open 6.51
Regular Market Previous Close 6.53
Regular Market Price 6.1
Regular Market Time 1,791,921,601
Regular Market Volume 326,681
Return On Assets -0.19372
Return On Equity -1.35146
Revenue Per Share 2.213
Sand P52 Week Change 0.17502642
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 8
Shares Outstanding 27,601,554
Shares Percent Shares Out 0.0911
Shares Short 2,514,044
Shares Short Previous Month Date 1,788,134,400
Shares Short Prior Month 2,518,952
Short Name Precision BioSciences, Inc.
Short Percent Of Float 0.0933
Short Ratio 9.96
Source Interval 15
State NC
Symbol DTIL
Target High Price 60.0
Target Low Price 18.0
Target Mean Price 29.4
Target Median Price 20.0
Total Cash 87,549,000
Total Cash Per Share 3.172
Total Debt 28,101,000
Total Revenue 45,055,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -1.35
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 6.369575
Two Hundred Day Average Change -0.26957512
Two Hundred Day Average Change Percent -0.042322308
Type Disp Equity
Volume 326,681
Website https://precisionbiosciences.com
Zip 27,701