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Precision BioSciences, Inc. (DTIL)

Healthcare | Biotechnology | Durham, United States | NasdaqCM
7.78 USD -0.62 (-7.381%) ⇩ (Aug. 28, 2026, 4 p.m. EDT)
After hours: 7.85 +0.07 (0.900%) ⇧ (Aug. 28, 2026, 7:30 p.m. EDT)

Short-term:★★⯪☆☆Long-term:⯪☆☆☆☆Dividends:☆☆☆☆☆
Hot Take | Aug. 22, 2026, 5:04 a.m. EDT

The long-term investment case is effectively broken. Despite a 'strong buy' analyst recommendation driven by potential clinical data, the company's price history tells a different story: a catastrophic multi-year decline where the stock has lost over 98% of its value. The market has punished the business repeatedly, with four consecutive years of negative annual returns, signaling that investors see no sustainable path to recovery. This is not a value trap; it is a deteriorating asset where the balance sheet is strained by negative free cash flow and the business model has failed to generate returns on equity or assets for years. The recent price surge is likely a reaction to specific trial data, but without a proven track record of profitability or consistent growth, this remains a high-risk gamble rather than a solid investment. On the short end, the recent rally has created some local resistance, and the lack of a clear trend reversal keeps the immediate outlook neutral-to-bearish. There is no dividend to provide any cushion.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoTheta ✓0.091884
MSTL0.096969
AutoARIMA0.097022
AutoETS0.097022

Forecast horizon: 45 days | Selected: AutoTheta

Forecast Reliability
Score 40%
H-stat 0.62
Ljung-Box p 0.000
Jarque-Bera p 0.102
Excess Kurtosis -0.58
Attribute Value
Sector Healthcare
Debt to Equity Ratio 62.043
Revenue per Share 2.213
Market Cap 214,740,096
Forward P/E -4.18
Beta 1.23
Profit Margins -117.04%
Website https://precisionbiosciences.com

As of Aug. 22, 2026, 5:04 a.m. EDT: Speculators are positioning defensively with heavy put volume at the $2.5 strike, suggesting a fear of further downside or a hedge against volatility. Call interest is concentrated near-the-money and slightly out-of-the-money, indicating a desire for modest gains rather than a speculative moonshot. The implied volatility is elevated relative to deep OTM strikes, reflecting uncertainty around the upcoming catalysts and trial results.


Info Dump

Attribute Value
52 Week Change 0.67999995
Address1 302 East Pettigrew St.
Address2 Suite A-100
All Time High 710.1
All Time Low 3.53
Ask 7.84
Ask Size 1
Audit Risk 3
Average Analyst Rating 1.0 - Strong Buy
Average Daily Volume10 Day 306,760
Average Daily Volume3 Month 423,932
Average Volume 423,932
Average Volume10Days 306,760
Beta 1.229
Bid 7.81
Bid Size 1
Board Risk 6
Book Value 1.713
City Durham
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 9
Country United States
Crypto Tradeable 0
Currency USD
Current Price 7.78
Current Ratio 12.822
Custom Price Alert Confidence HIGH
Date Short Interest 1,786,665,600
Day High 8.43
Day Low 7.72
Debt To Equity 62.043
Display Name Precision BioSciences
Earnings Timestamp 1,786,019,400
Earnings Timestamp End 1,793,622,600
Earnings Timestamp Start 1,793,622,600
Ebitda -35,148,000
Ebitda Margins -0.78011
Enterprise To Ebitda -4.418
Enterprise To Revenue 3.447
Enterprise Value 155,292,096
Eps Current Year -3.86667
Eps Forward -1.86
Eps Trailing Twelve Months -1.22
Esg Populated 0
Exchange NCM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fax 480 393 5553
Fifty Day Average 7.7694
Fifty Day Average Change 0.01060009
Fifty Day Average Change Percent 0.0013643383
Fifty Two Week Change Percent 67.99999
Fifty Two Week High 9.62
Fifty Two Week High Change -1.8399997
Fifty Two Week High Change Percent -0.19126816
Fifty Two Week Low 3.53
Fifty Two Week Low Change 4.25
Fifty Two Week Low Change Percent 1.203966
Fifty Two Week Range 3.53 - 9.62
Financial Currency USD
First Trade Date Milliseconds 1,553,779,800,000
Float Shares 25,456,637
Forward Eps -1.86
Forward P E -4.182796
Free Cashflow -16,252,500
Full Exchange Name NasdaqCM
Full Time Employees 67
Fullday Change -0.619999
Fullday Change Percent -7.38095
Fullday Price 7.85
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,785,542,400
Gross Margins 1.0
Gross Profits 45,055,000
Has Pre Post Market Data 1
Held Percent Insiders 0.080249995
Held Percent Institutions 0.68668
Implied Shares Outstanding 27,601,554
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Last Split Date 1,707,868,800
Last Split Factor 1:30
Long Business Summary Precision BioSciences, Inc., a clinical stage gene editing company, develops in vivo gene editing therapies for gene edits, including gene insertion, excision, and elimination in the United States. The company offers ARCUS, a genome editing platform for DNA genome insertion, removal, and repair. It also provides PBGENE-HBV for the treatment of chronic hepatitis B virus (HBV) to eliminate covalently closed circular DNA with direct cuts and edits, as well as to inactivate integrated HBV DNA with the goal of long-lasting reductions in hepatitis B surface antigen; and PBGENE-DMD (Excision) for the treatment of Duchenne muscular dystrophy. In addition, the company develops PBGENE-3243 for the treatment of m.3243 associated mitochondrial diseases; and iECURE-OTC (Insertion) for ornithine transcarbamylase deficiency. It has collaboration agreements with TG Cell Therapy, Inc. to develop, manufacture, and commercialize azercabtagene zapreleucel for autoimmune diseases and other indications; and iECURE, Inc., an ARCUS-mediated targeted gene insertion. Precision BioSciences, Inc. was incorporated in 2006 and is headquartered in Durham, North Carolina.
Long Name Precision BioSciences, Inc.
Market us_market
Market Cap 214,740,096
Market State CLOSED
Max Age 86,400
Message Board Id finmb_41018856
Most Recent Quarter 1,782,777,600
Net Income To Common -53,617,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 231,577,038
Number Of Analyst Opinions 5
Open 8.37
Operating Cashflow -51,899,000
Operating Margins -0.80779
Overall Risk 7
Payout Ratio 0.0
Phone 919 314 5512
Post Market Change 0.069999695
Post Market Change Percent 0.89973897
Post Market Price 7.85
Post Market Time 1,787,959,804
Previous Close 8.4
Price Eps Current Year -2.0120673
Price Hint 2
Price To Book 4.5417395
Price To Sales Trailing12 Months 4.7661767
Profit Margins -1.17039
Quick Ratio 12.262
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.0
Region US
Regular Market Change -0.619999
Regular Market Change Percent -7.38095
Regular Market Day High 8.43
Regular Market Day Low 7.72
Regular Market Day Range 7.72 - 8.43
Regular Market Open 8.37
Regular Market Previous Close 8.4
Regular Market Price 7.78
Regular Market Time 1,787,947,201
Regular Market Volume 222,325
Return On Assets -0.19372
Return On Equity -1.35146
Revenue Per Share 2.213
Sand P52 Week Change 0.20504117
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 8
Shares Outstanding 27,601,554
Shares Percent Shares Out 0.087
Shares Short 2,401,307
Shares Short Previous Month Date 1,784,073,600
Shares Short Prior Month 2,384,495
Short Name Precision BioSciences, Inc.
Short Percent Of Float 0.089099996
Short Ratio 8.29
Source Interval 15
State NC
Symbol DTIL
Target High Price 60.0
Target Low Price 18.0
Target Mean Price 29.4
Target Median Price 20.0
Total Cash 87,549,000
Total Cash Per Share 3.172
Total Debt 28,101,000
Total Revenue 45,055,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -1.22
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 6.103175
Two Hundred Day Average Change 1.676825
Two Hundred Day Average Change Percent 0.27474633
Type Disp Equity
Volume 222,325
Website https://precisionbiosciences.com
Zip 27,701