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Dianthus Therapeutics, Inc. (DNTH)

Healthcare | Biotechnology | New York, United States | NasdaqCM
105.84 USD -5.70 (-5.110%) ⇩ (Aug. 28, 2026, 4 p.m. EDT)
After hours: 115.40 +9.56 (9.033%) ⇧ (Aug. 28, 2026, 7:47 p.m. EDT)

Short-term:★★★★☆Long-term:★★★☆☆Dividends:☆☆☆☆☆
Hot Take | Aug. 22, 2026, 4:09 a.m. EDT

DNTH presents a classic biotech dichotomy: a fortress balance sheet with ample cash reserves and zero debt contrasts sharply with a seven-year price history of severe underperformance. The recent surge to near 52-week highs, driven by the initiation of a major Phase 3 clinical trial, has reignited institutional interest, evidenced by heavy buying from major asset managers. While the statistical forecasting models offer only a weak lean upward, the technical momentum remains robust with the stock trading well above its 200-day average. Investors should view this as a high-risk, high-reward speculative play where the downside is cushioned by the company's liquidity, but the path to profitability remains steep. The options market is hedging against a drop to the $70s while betting on a breakout toward $150, reflecting the binary nature of the upcoming trial results.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoTheta ✓0.094266
MSTL0.124291
AutoARIMA0.135528
AutoETS0.135955

Forecast horizon: 45 days | Selected: AutoTheta

Forecast Reliability
Score 34%
H-stat 5.65
Ljung-Box p 0.000
Jarque-Bera p 0.506
Excess Kurtosis -0.48
Attribute Value
Sector Healthcare
Debt to Equity Ratio 0.11
Revenue per Share 0.041
Market Cap 5,785,873,920
Forward P/E -22.31
Beta 0.08
Website https://dianthustx.com

As of Aug. 22, 2026, 4:09 a.m. EDT: Speculators are positioning for a range-bound recovery with significant downside protection at the $65-$80 level via deep out-of-the-money puts, while call interest clusters at $150-$165, suggesting a potential upside target if the Phase 3 trial data validates expectations. Implied volatility is elevated on deep strikes, indicating uncertainty around binary outcomes.


Info Dump

Attribute Value
52 Week Change 3.437736
Address1 7 Times Square
Address2 43rd Floor
All Time High 336.0
All Time Low 5.12
Ask 106.69
Ask Size 1
Audit Risk 8
Average Analyst Rating 1.0 - Strong Buy
Average Daily Volume10 Day 570,220
Average Daily Volume3 Month 1,046,374
Average Volume 1,046,374
Average Volume10Days 570,220
Beta 0.082
Bid 106.24
Bid Size 1
Board Risk 6
Book Value 21.388
City New York
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 9
Country United States
Crypto Tradeable 0
Currency USD
Current Price 105.84
Current Ratio 26.1
Custom Price Alert Confidence HIGH
Date Short Interest 1,786,665,600
Day High 111.31
Day Low 105.6
Debt To Equity 0.11
Display Name Dianthus Therapeutics
Earnings Timestamp 1,785,873,600
Earnings Timestamp End 1,793,908,800
Earnings Timestamp Start 1,793,908,800
Ebitda -217,720,992
Ebitda Margins 0.0
Enterprise To Ebitda -23.124
Enterprise To Revenue 2,644.206
Enterprise Value 5,034,568,704
Eps Current Year -3.92
Eps Forward -4.74333
Eps Trailing Twelve Months -4.24
Esg Populated 0
Exchange NCM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 103.3468
Fifty Day Average Change 2.4931946
Fifty Day Average Change Percent 0.024124546
Fifty Two Week Change Percent 343.7736
Fifty Two Week High 117.88
Fifty Two Week High Change -12.040001
Fifty Two Week High Change Percent -0.102137774
Fifty Two Week Low 23.39
Fifty Two Week Low Change 82.45
Fifty Two Week Low Change Percent 3.5250106
Fifty Two Week Range 23.39 - 117.88
Financial Currency USD
First Trade Date Milliseconds 1,529,587,800,000
Float Shares 55,849,917
Forward Eps -4.74333
Forward P E -22.313437
Free Cashflow -92,210,496
Full Exchange Name NasdaqCM
Full Time Employees 92
Fullday Change -5.7
Fullday Change Percent -5.11028
Fullday Price 115.4
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,785,542,400
Gross Margins 1.0
Gross Profits 1,904,000
Has Pre Post Market Data 1
Held Percent Insiders 0.00124
Held Percent Institutions 1.28112
Implied Shares Outstanding 54,666,233
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Dianthus Therapeutics, Inc., a clinical-stage biotechnology company, engages in the development of therapies for patients with severe autoimmune diseases. Its lead clinical-stage candidate, claseprubart, a monoclonal antibody engineered with extended half-life, improved potency, and high selectivity for only the active C1s complement protein; and DNTH212, a bifunctional fusion protein that targets plasmacytoid dendritic cell (pDC) BDCA2 to reduce Type 1 interferon production, while simultaneously inhibiting BAFF/APRIL to suppress B cell function. Dianthus Therapeutics, Inc. was founded in 2019 and is headquartered in New York, New York.
Long Name Dianthus Therapeutics, Inc.
Market us_market
Market Cap 5,785,873,920
Market State CLOSED
Max Age 86,400
Message Board Id finmb_631649032
Most Recent Quarter 1,782,777,600
Net Income To Common -192,246,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 6,243,395,272
Number Of Analyst Opinions 13
Open 111.31
Operating Cashflow -155,375,008
Operating Margins -80.79106
Overall Risk 8
Payout Ratio 0.0
Phone 929 999 4055
Post Market Change 9.560005
Post Market Change Percent 9.032507
Post Market Price 115.4
Post Market Time 1,787,960,875
Previous Close 111.54
Price Eps Current Year -26.999998
Price Hint 2
Price To Book 4.948569
Price To Sales Trailing12 Months 3,038.7993
Profit Margins 0.0
Quick Ratio 25.791
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.0
Region US
Regular Market Change -5.7
Regular Market Change Percent -5.11028
Regular Market Day High 111.31
Regular Market Day Low 105.6
Regular Market Day Range 105.6 - 111.31
Regular Market Open 111.31
Regular Market Previous Close 111.54
Regular Market Price 105.84
Regular Market Time 1,787,947,201
Regular Market Volume 376,184
Return On Assets -0.1769
Return On Equity -0.26065
Revenue Growth 2.943
Revenue Per Share 0.041
Sand P52 Week Change 0.20204377
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 8
Shares Outstanding 54,666,233
Shares Percent Shares Out 0.1505
Shares Short 8,418,356
Shares Short Previous Month Date 1,784,073,600
Shares Short Prior Month 9,220,028
Short Name Dianthus Therapeutics, Inc.
Short Percent Of Float 0.1727
Short Ratio 10.01
Source Interval 15
State NY
Symbol DNTH
Target High Price 200.0
Target Low Price 109.0
Target Mean Price 137.61539
Target Median Price 132.0
Total Cash 886,812,992
Total Cash Per Share 15.855
Total Debt 1,287,000
Total Revenue 1,904,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -4.24
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 74.27775
Two Hundred Day Average Change 31.562248
Two Hundred Day Average Change Percent 0.424922
Type Disp Equity
Volume 376,184
Website https://dianthustx.com
Zip 10,036