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Dianthus Therapeutics, Inc. (DNTH)

Healthcare | Biotechnology | New York, United States | NasdaqCM
74.53 USD -0.23 (-0.308%) ⇩ (Oct. 15, 2026, 4 p.m. EDT)

Short-term:★★★☆☆Long-term:★★⯪☆☆Dividends:☆☆☆☆☆
Hot Take ↕ | Oct. 10, 2026, 10:25 a.m. EDT

Dianthus Therapeutics presents a classic biotech dilemma: a fortress balance sheet masking a lack of commercial scale. The company sits on nearly $900 million in cash against negligible debt, giving it ample runway to fund its pipeline without immediate dilution. Yet, the stock has lost over three-quarters of its value over the past seven years, a stark reminder of the graveyard that lies ahead for unproven therapies. While analysts are screaming 'Strong Buy' based on the upcoming Phase 3 trial, the price action tells a different story, dropping 16% in just two weeks as investors digest the risk of failure. The recent recovery in annual returns is encouraging, but the cumulative drag remains severe. For now, this is a speculative hold rather than a core investment; the cash pile provides a safety net, but the business model has yet to prove it can generate sustainable profits beyond the lab.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoETS ✓0.057203
MSTL0.057534
AutoARIMA0.057587
AutoTheta0.064320

Forecast horizon: 45 days | Selected: AutoETS

Forecast Reliability
Score 31%
H-stat 1.96
Ljung-Box p 0.000
Jarque-Bera p 0.001
Excess Kurtosis 1.14
Attribute Value
Sector Healthcare
Debt to Equity Ratio 0.11
Revenue per Share 0.041
Market Cap 4,074,274,304
Forward P/E -16.16
Beta 0.18
Website https://dianthustx.com

As of Oct. 10, 2026, 10:25 a.m. EDT: Speculators are positioning for a range-bound outcome between $60 and $100 over the next year. Near-term expiration shows elevated implied volatility with open interest clustering around the current price ($80-$90), suggesting hedging against further drops. However, the January 2027 call wall at the $100 strike indicates a bullish thesis for a recovery to the upper end of the 52-week range, while deep out-of-the-money puts suggest a tail-risk hedge against a deeper collapse.


Info Dump

Attribute Value
52 Week Change 1.0906031
Address1 7 Times Square
Address2 43rd Floor
All Time High 336.0
All Time Low 5.12
Ask 99.21
Ask Size 2
Audit Risk 8
Average Analyst Rating 1.1 - Strong Buy
Average Daily Volume10 Day 909,170
Average Daily Volume3 Month 803,464
Average Volume 803,464
Average Volume10Days 909,170
Beta 0.181
Bid 58.02
Bid Size 2
Board Risk 6
Book Value 21.388
City New York
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 9
Country United States
Crypto Tradeable 0
Currency USD
Current Price 74.53
Current Ratio 26.1
Custom Price Alert Confidence HIGH
Date Short Interest 1,790,726,400
Day High 77.55
Day Low 72.67
Debt To Equity 0.11
Display Name Dianthus Therapeutics
Dividend Yield 0.0
Earnings Timestamp 1,785,873,600
Earnings Timestamp End 1,793,908,800
Earnings Timestamp Start 1,793,908,800
Ebitda -217,720,992
Ebitda Margins 0.0
Enterprise To Ebitda -15.08
Enterprise To Revenue 1,724.403
Enterprise Value 3,283,263,232
Eps Current Year -3.81404
Eps Forward -4.61098
Eps Trailing Twelve Months -4.24
Esg Populated 0
Exchange NCM
Exchange Data Delayed By 15
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 100.0746
Fifty Day Average Change -25.544601
Fifty Day Average Change Percent -0.25525558
Fifty Two Week Change Percent 109.06031
Fifty Two Week High 117.88
Fifty Two Week High Change -43.35
Fifty Two Week High Change Percent -0.36774686
Fifty Two Week Low 32.22
Fifty Two Week Low Change 42.309998
Fifty Two Week Low Change Percent 1.3131593
Fifty Two Week Range 32.22 - 117.88
Financial Currency USD
First Trade Date Milliseconds 1,529,587,800,000
Float Shares 55,849,917
Forward Eps -4.61098
Forward P E -16.163591
Free Cashflow -92,210,496
Full Exchange Name NasdaqCM
Full Time Employees 92
Fullday Change -0.23000336
Fullday Change Percent -0.30765563
Fullday Price 74.53
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,790,812,800
Gross Margins 1.0
Gross Profits 1,904,000
Has Pre Post Market Data 1
Held Percent Insiders 0.00124
Held Percent Institutions 1.28671
Implied Shares Outstanding 54,666,233
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Dianthus Therapeutics, Inc., a clinical-stage biotechnology company, engages in the development of therapies for patients with severe autoimmune diseases. Its lead clinical-stage candidate, claseprubart, a monoclonal antibody engineered with extended half-life, improved potency, and high selectivity for only the active C1s complement protein; and DNTH212, a bifunctional fusion protein that targets plasmacytoid dendritic cell (pDC) BDCA2 to reduce Type 1 interferon production, while simultaneously inhibiting BAFF/APRIL to suppress B cell function. Dianthus Therapeutics, Inc. was founded in 2019 and is headquartered in New York, New York.
Long Name Dianthus Therapeutics, Inc.
Market us_market
Market Cap 4,074,274,304
Market State PRE
Max Age 86,400
Message Board Id finmb_631649032
Most Recent Quarter 1,782,777,600
Net Income To Common -192,246,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 5,222,033,530
Number Of Analyst Opinions 15
Open 75.77
Operating Cashflow -155,375,008
Operating Margins -80.79106
Overall Risk 8
Payout Ratio 0.0
Phone 929 999 4055
Previous Close 74.76
Price Eps Current Year -19.540958
Price Hint 2
Price To Book 3.4846642
Price To Sales Trailing12 Months 2,139.8499
Profit Margins 0.0
Quick Ratio 25.791
Quote Source Name Delayed Quote
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.05882
Region US
Regular Market Change -0.230003
Regular Market Change Percent -0.307656
Regular Market Day High 77.55
Regular Market Day Low 72.67
Regular Market Day Range 72.67 - 77.55
Regular Market Open 75.77
Regular Market Previous Close 74.76
Regular Market Price 74.53
Regular Market Time 1,792,094,401
Regular Market Volume 943,572
Return On Assets -0.1769
Return On Equity -0.26065
Revenue Growth 2.943
Revenue Per Share 0.041
Sand P52 Week Change 0.16207206
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 8
Shares Outstanding 54,666,233
Shares Percent Shares Out 0.1634
Shares Short 9,140,581
Shares Short Previous Month Date 1,788,134,400
Shares Short Prior Month 8,429,902
Short Name Dianthus Therapeutics, Inc.
Short Percent Of Float 0.1875
Short Ratio 10.65
Source Interval 15
State NY
Symbol DNTH
Target High Price 200.0
Target Low Price 122.0
Target Mean Price 140.8
Target Median Price 134.0
Total Cash 886,812,992
Total Cash Per Share 15.855
Total Debt 1,287,000
Total Revenue 1,904,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -4.24
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 82.9027
Two Hundred Day Average Change -8.372704
Two Hundred Day Average Change Percent -0.10099434
Type Disp Equity
Volume 943,572
Website https://dianthustx.com
Zip 10,036