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Dianthus Therapeutics, Inc. (DNTH)

Healthcare | Biotechnology | New York, United States | NasdaqCM
91.92 USD -1.34 (-1.437%) ⇩ (April 20, 2026, 4 p.m. EDT)

Short-term: ★★★★★ | Long-term: ★☆☆☆☆ | Dividends: ☆☆☆☆☆
Hot Take | April 19, 2026, 12:30 a.m. EDT

While the fundamentals deteriorate severely with -78.6% revenue growth and negative cash flow, the risk-reward is compelling due to the wide safety margin. The stock is up 33% year-over-year, yet analysts see a massive runway to $125-$200 based on potential FDA approvals. The options market is screaming aggression rather than fear; with 99.9% of the implicit capital flow tilted into calls, the market believes the downside is priced in at current levels ($79 low). With a beta of only 0.21 (decoupling from market risk), this is a high-conviction momentum play on a potential catalyst, not this earnings report. If the clinical data is promising, the stock could run independently of the S&P; if it fails, the wrecking ball is already lobbed. This is for the bulls betting on the next big headline.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoTheta ✓0.292235
MSTL0.302718
AutoARIMA0.313055
AutoETS0.313061

Forecast horizon: 45 days | Selected: AutoTheta

Forecast Reliability
Score 40%
H-stat 41.70
Ljung-Box p 0.000
Jarque-Bera p 0.048
Excess Kurtosis -1.77
Attribute Value
Sector Healthcare
Debt to Equity Ratio 0.281
Revenue per Share 0.053
Market Cap 5,004,931,072
Forward P/E -17.97
Beta 0.21
Website https://dianthustx.com

As of April 19, 2026, 12:30 a.m. EDT: Options activity shows a massive bullish skew. Speculators are heavily positioning calls, with 93.2% of total option volume going to calls (541 vs 38). There is significant Open Interest at near-term strikes (e.g., 65/90 May Calls, 75/100 Aug Calls) suggesting a target range of 75-100, well above the current price. Conversely, put activity is negligible (mostly deep OTM in 2027), indicating speculators are not hedging for downside moves but are almost exclusively betting on upward momentum.


Info Dump

Attribute Value
52 Week Change 3.2030177
Address1 7 Times Square
Address2 43rd Floor
All Time High 336.0
All Time Low 5.12
Ask 92.42
Ask Size 1
Audit Risk 9
Average Analyst Rating 1.0 - Strong Buy
Average Daily Volume10 Day 669,980
Average Daily Volume3 Month 1,055,209
Average Volume 1,055,209
Average Volume10Days 669,980
Beta 0.212
Bid 91.51
Bid Size 1
Board Risk 6
Book Value 11.415
City New York
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 10
Country United States
Crypto Tradeable 0
Currency USD
Current Price 91.92
Current Ratio 13.323
Custom Price Alert Confidence HIGH
Date Short Interest 1,774,915,200
Day High 93.5399
Day Low 91.1
Debt To Equity 0.281
Display Name Dianthus Therapeutics
Earnings Timestamp 1,773,059,400
Earnings Timestamp End 1,778,502,600
Earnings Timestamp Start 1,778,502,600
Ebitda -177,822,000
Ebitda Margins 0.0
Enterprise To Ebitda -20.722
Enterprise To Revenue 1,809.86
Enterprise Value 3,684,873,984
Eps Current Year -4.65429
Eps Forward -5.11429
Eps Trailing Twelve Months -4.2
Esg Populated 0
Exchange NCM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 71.962
Fifty Day Average Change 19.958
Fifty Day Average Change Percent 0.27734083
Fifty Two Week Change Percent 320.30176
Fifty Two Week High 96.5
Fifty Two Week High Change -4.580002
Fifty Two Week High Change Percent -0.04746116
Fifty Two Week Low 16.64
Fifty Two Week Low Change 75.28
Fifty Two Week Low Change Percent 4.524039
Fifty Two Week Range 16.64 - 96.5
Financial Currency USD
First Trade Date Milliseconds 1,529,587,800,000
Float Shares 41,979,379
Forward Eps -5.11429
Forward P E -17.973167
Free Cashflow -75,447,128
Full Exchange Name NasdaqCM
Full Time Employees 92
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,775,001,600
Gross Margins 1.0
Gross Profits 2,036,000
Has Pre Post Market Data 1
Held Percent Insiders 0.0012800001
Held Percent Institutions 0.9576
Implied Shares Outstanding 54,448,771
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Dianthus Therapeutics, Inc., a clinical-stage biotechnology company, engages in the development of therapies for patients with severe autoimmune diseases. Its lead clinical-stage candidate, claseprubart, a monoclonal antibody engineered with extended half-life, improved potency, and high selectivity for only the active C1s complement protein; and DNTH212, a bifunctional fusion protein that targets plasmacytoid dendritic cell (pDC) BDCA2 to reduce Type 1 interferon production, while simultaneously inhibiting BAFF/APRIL to suppress B cell function. Dianthus Therapeutics, Inc. was founded in 2019 and is headquartered in New York, New York.
Long Name Dianthus Therapeutics, Inc.
Market us_market
Market Cap 5,004,931,072
Market State PRE
Max Age 86,400
Message Board Id finmb_631649032
Most Recent Quarter 1,767,139,200
Net Income To Common -162,336,992
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 5,003,297,567
Number Of Analyst Opinions 13
Open 93.0
Operating Cashflow -129,060,000
Operating Margins -244.86267
Overall Risk 10
Payout Ratio 0.0
Phone 929 999 4055
Pre Market Change 0.0
Pre Market Change Percent 0.0
Pre Market Price 91.92
Pre Market Time 1,776,769,405
Previous Close 93.26
Price Eps Current Year -19.74952
Price Hint 2
Price To Book 8.052563
Price To Sales Trailing12 Months 2,458.2175
Profit Margins 0.0
Quick Ratio 13.157
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.0
Region US
Regular Market Change -1.34
Regular Market Change Percent -1.43685
Regular Market Day High 93.5399
Regular Market Day Low 91.1
Regular Market Day Range 91.1 - 93.5399
Regular Market Open 93.0
Regular Market Previous Close 93.26
Regular Market Price 91.92
Regular Market Time 1,776,715,201
Regular Market Volume 526,956
Return On Assets -0.24577999
Return On Equity -0.38382998
Revenue Growth -0.786
Revenue Per Share 0.053
Sand P52 Week Change 0.34445214
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 8
Shares Outstanding 54,448,771
Shares Percent Shares Out 0.1666
Shares Short 9,069,811
Shares Short Previous Month Date 1,772,150,400
Shares Short Prior Month 7,893,078
Short Name Dianthus Therapeutics, Inc.
Short Percent Of Float 0.1919
Short Ratio 5.73
Source Interval 15
State NY
Symbol DNTH
Target High Price 200.0
Target Low Price 98.0
Target Mean Price 125.46154
Target Median Price 123.0
Total Cash 404,295,008
Total Cash Per Share 9.091
Total Debt 1,386,000
Total Revenue 2,036,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -4.2
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 43.91455
Two Hundred Day Average Change 48.005447
Two Hundred Day Average Change Percent 1.0931559
Type Disp Equity
Volume 526,956
Website https://dianthustx.com
Zip 10,036