| Indicators | Browse All

Definium Therapeutics, Inc. (DFTX)

Healthcare | Biotechnology | New York, United States | NasdaqGS
40.98 USD -2.84 (-6.481%) ⇩ (Aug. 28, 2026, 4 p.m. EDT)
After hours: 40.98 -0.01 (-0.005%) ⇩ (Aug. 28, 2026, 7:58 p.m. EDT)

Short-term:★★★★☆Long-term:★★★⯪☆Dividends:☆☆☆☆☆
Hot Take | Aug. 22, 2026, 2:29 a.m. EDT

The immediate outlook is aggressively bullish, driven by a perfect storm of clinical validation and capital inflow. Definium has successfully navigated the biotech gauntlet with positive Phase 3 data for DT120 in depression and real-world efficacy in generalized anxiety disorder, securing a $700 million financing round that validates the commercial potential of its late-stage pipeline. The stock has rallied nearly 90% over the last six months, outperforming its 200-day average significantly, and technicals suggest momentum is still intact. However, the fundamental reality remains precarious: the company burns cash rapidly with negative operating cash flow and no earnings in sight, relying entirely on future drug sales and capital markets to survive. The balance sheet is currently healthy due to the fresh cash infusion, but the path to profitability is long and fraught with execution risk. While the short-term catalysts are potent enough to justify a high-conviction entry for momentum traders, the long-term investment case hinges on flawless execution of the commercial rollout and the ability to generate revenue before the cash runway evaporates. The disconnect between the speculative frenzy and the lack of current profitability creates a high-volatility environment where the thesis can double quickly or collapse if a single trial falters.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoETS ✓0.031443
AutoTheta0.113416
AutoARIMA1.203580
MSTL2.197930

Forecast horizon: 45 days | Selected: AutoETS

Forecast Reliability
Score 42%
H-stat 1.56
Ljung-Box p 0.310
Jarque-Bera p 0.925
Excess Kurtosis -0.28
Attribute Value
Sector Healthcare
Debt to Equity Ratio 3.97
Market Cap 5,506,357,248
Forward P/E -21.85
Beta 2.26
Website https://definiumtx.com

As of Aug. 22, 2026, 2:29 a.m. EDT: Speculators are heavily positioned for upside continuation, evidenced by massive open interest walls at the $60 and $65 strikes for near-term expirations and significant volume at the $45 ATM level. While there is some defensive put buying at lower strikes ($20-$40 range), the overwhelming capital deployment is in calls, suggesting a belief that the recent rally will persist despite elevated implied volatility.


Info Dump

Attribute Value
52 Week Change 3.4884996
Address1 One World Trade Center
Address2 Suite 8500
All Time High 86.55
All Time Low 0.015
Ask 41.55
Ask Size 1
Audit Risk 7
Average Analyst Rating 1.2 - Strong Buy
Average Daily Volume10 Day 1,686,660
Average Daily Volume3 Month 2,966,473
Average Volume 2,966,473
Average Volume10Days 1,686,660
Beta 2.258
Bid 40.93
Bid Size 1
Board Risk 3
Book Value 6.837
City New York
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 8
Country United States
Crypto Tradeable 0
Currency USD
Current Price 40.98
Current Ratio 6.947
Custom Price Alert Confidence HIGH
Date Short Interest 1,786,665,600
Day High 43.3799
Day Low 40.851
Debt To Equity 3.97
Display Name Definium Therapeutics
Earnings Call Timestamp End 1,786,048,200
Earnings Call Timestamp Start 1,786,048,200
Earnings Timestamp 1,786,046,400
Earnings Timestamp End 1,793,908,800
Earnings Timestamp Start 1,793,908,800
Ebitda Margins 0.0
Enterprise Value 4,458,945,536
Eps Current Year -3.16286
Eps Forward -1.87538
Eps Trailing Twelve Months -3.43
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 43.5304
Fifty Day Average Change -2.5503998
Fifty Day Average Change Percent -0.058588937
Fifty Two Week Change Percent 348.84998
Fifty Two Week High 49.7
Fifty Two Week High Change -8.720001
Fifty Two Week High Change Percent -0.17545274
Fifty Two Week Low 8.7
Fifty Two Week Low Change 32.28
Fifty Two Week Low Change Percent 3.7103448
Fifty Two Week Range 8.7 - 49.7
Financial Currency USD
First Trade Date Milliseconds 1,479,220,200,000
Float Shares 124,500,385
Forward Eps -1.87538
Forward P E -21.85157
Free Cashflow 7,611,500
Full Exchange Name NasdaqGS
Full Time Employees 105
Fullday Change -2.84
Fullday Change Percent -6.48106
Fullday Price 40.975
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,785,542,400
Gross Margins 0.0
Has Pre Post Market Data 1
Held Percent Insiders 0.01727
Held Percent Institutions 0.88132006
Implied Shares Outstanding 134,366,950
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Last Split Date 1,661,731,200
Last Split Factor 1:15
Long Business Summary Definium Therapeutics, Inc., a clinical biopharmaceutical company, develops novel product candidates to treat brain health disorders. The company's lead product candidates DT120, which is in phase 3 for the treatment of generalized anxiety disorder, major depressive disorder, and other brain health disorders; and DT402, a R-enantiomer of 3,4-methylenedioxymethamphetamine, which is in phase 2a clinical trials for the treatment of autism spectrum disorder. The company was formerly known as Mind Medicine (MindMed) Inc. and changed its name to Definium Therapeutics, Inc. in January 2026. Definium Therapeutics, Inc. is headquartered in New York, New York.
Long Name Definium Therapeutics, Inc.
Market us_market
Market Cap 5,506,357,248
Market State CLOSED
Max Age 86,400
Message Board Id finmb_631045282
Most Recent Quarter 1,782,777,600
Net Income To Common -353,784,992
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 5,888,094,115
Number Of Analyst Opinions 17
Open 43.18
Operating Cashflow -167,951,008
Operating Margins 0.0
Overall Risk 4
Payout Ratio 0.0
Phone 212 220 6633
Post Market Change -0.005001068
Post Market Change Percent -0.01220368
Post Market Price 40.975
Post Market Time 1,787,961,509
Previous Close 43.82
Price Eps Current Year -12.956628
Price Hint 2
Price To Book 5.993857
Profit Margins 0.0
Quick Ratio 6.895
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.22222
Region US
Regular Market Change -2.84
Regular Market Change Percent -6.48106
Regular Market Day High 43.3799
Regular Market Day Low 40.851
Regular Market Day Range 40.851 - 43.3799
Regular Market Open 43.18
Regular Market Previous Close 43.82
Regular Market Price 40.98
Regular Market Time 1,787,947,201
Regular Market Volume 1,801,715
Return On Assets -0.20641
Return On Equity -0.64087
Sand P52 Week Change 0.20204377
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 2
Shares Outstanding 134,366,950
Shares Percent Shares Out 0.0668
Shares Short 8,969,420
Shares Short Previous Month Date 1,784,073,600
Shares Short Prior Month 10,644,685
Short Name Definium Therapeutics, Inc.
Short Percent Of Float 0.0672
Short Ratio 4.3
Source Interval 15
State NY
Symbol DFTX
Target High Price 90.0
Target Low Price 52.0
Target Mean Price 67.47059
Target Median Price 66.0
Total Cash 1,083,879,040
Total Cash Per Share 8.067
Total Debt 36,467,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -3.43
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 24.2578
Two Hundred Day Average Change 16.7222
Two Hundred Day Average Change Percent 0.6893536
Type Disp Equity
Volume 1,801,715
Website https://definiumtx.com
Zip 10,007