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Definium Therapeutics, Inc. (DFTX)

Healthcare | Biotechnology | New York, United States | NasdaqGS
34.38 USD -0.82 (-2.330%) ⇩ (Oct. 13, 2026, 4 p.m. EDT)

Short-term:★★★⯪☆Long-term:★★★☆☆Dividends:☆☆☆☆☆
Hot Take ↕ | Oct. 10, 2026, 7:55 a.m. EDT

Definium presents a classic biotech dichotomy: a transformative late-stage pipeline versus precarious financials. The company recently secured a Phase 3 win for DT120 and raised $700 million, which validates the core business thesis and provides a runway to execute. Fundamentally, the balance sheet is surprisingly robust for the sector, with cash significantly outweighing debt and a current ratio near 7x, meaning the stock is not priced on an immediate bankruptcy risk. However, the earnings are currently negative, and the stock trades at a premium to book value, reflecting high expectations for the upcoming data readouts. The short-term outlook is volatile. While the recent price action shows some weakness relative to the 50-day average, the options market is screaming for movement. The heavy call volume at strikes like 50 and 70 suggests traders are betting on a successful trial readout to drive a massive gap-up. Conversely, the deep put walls at lower strikes act as a safety valve, implying that if the data is merely 'okay' rather than a blockbuster, the stock could face a sharp correction. The statistical forecast model offers almost no guidance here, correctly identifying the noise inherent in pre-data trading. Long-term, the investment case rests entirely on the execution of the DT120 program and the potential for the GAD data to redefine the treatment landscape. If the company can convert this capital raise into approved products, the valuation expansion could be substantial. However, the lack of dividends and the reliance on future clinical success mean this is a high-risk, high-reward speculative play rather than a steady income vehicle. The current price reflects a market that believes the upside potential outweighs the risk of failure, but the binary nature of the next few months makes holding positions stressful.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoETS ✓0.071353
MSTL0.074000
AutoTheta0.335456
AutoARIMA0.424948

Forecast horizon: 45 days | Selected: AutoETS

Forecast Reliability
Score 30%
H-stat 12.32
Ljung-Box p 0.000
Jarque-Bera p 0.171
Excess Kurtosis -1.37
Attribute Value
Sector Healthcare
Debt to Equity Ratio 3.97
Market Cap 4,619,535,872
Forward P/E -17.72
Beta 2.19
Previous Name Mind Medicine (MindMed) Inc.
Website https://definiumtx.com

As of Oct. 10, 2026, 7:55 a.m. EDT: Speculators are positioning for significant volatility rather than a specific directional breakout. Call volume is heavily skewed toward out-of-the-money strikes (49, 50, 70), suggesting a bullish bias or a 'lottery ticket' strategy hoping for a catalyst-driven surge. However, put open interest is massive at lower strikes (7, 10, 20), creating a heavy floor that suggests a belief in a potential crash or a desire to profit from downside moves if the clinical trials fail. The implied volatility is elevated across the board, indicating the market expects a binary event.


Info Dump

Attribute Value
52 Week Change 1.7156398
Address1 One World Trade Center
Address2 Suite 8500
All Time High 86.55
All Time Low 0.015
Ask 44.08
Ask Size 2
Audit Risk 7
Average Analyst Rating 1.3 - Strong Buy
Average Daily Volume10 Day 2,193,240
Average Daily Volume3 Month 2,140,309
Average Volume 2,140,309
Average Volume10Days 2,193,240
Beta 2.194
Bid 25.02
Bid Size 2
Board Risk 3
Book Value 6.837
City New York
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 8
Country United States
Crypto Tradeable 0
Currency USD
Current Price 34.38
Current Ratio 6.947
Custom Price Alert Confidence HIGH
Date Short Interest 1,790,726,400
Day High 34.95
Day Low 34.03
Debt To Equity 3.97
Display Name Definium Therapeutics
Dividend Yield 0.0
Earnings Call Timestamp End 1,786,048,200
Earnings Call Timestamp Start 1,786,048,200
Earnings Timestamp 1,786,046,400
Earnings Timestamp End 1,793,908,800
Earnings Timestamp Start 1,793,908,800
Ebitda Margins 0.0
Enterprise Value 3,572,123,648
Eps Current Year -3.18136
Eps Forward -1.94055
Eps Trailing Twelve Months -3.43
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 15
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 40.0896
Fifty Day Average Change -5.7095985
Fifty Day Average Change Percent -0.14242095
Fifty Two Week Change Percent 171.56398
Fifty Two Week High 49.7
Fifty Two Week High Change -15.32
Fifty Two Week High Change Percent -0.30824947
Fifty Two Week Low 10.465
Fifty Two Week Low Change 23.915
Fifty Two Week Low Change Percent 2.2852366
Fifty Two Week Range 10.465 - 49.7
Financial Currency USD
First Trade Date Milliseconds 1,479,220,200,000
Float Shares 125,516,199
Forward Eps -1.94055
Forward P E -17.716627
Free Cashflow 7,611,500
Full Exchange Name NasdaqGS
Full Time Employees 105
Fullday Change -0.33000183
Fullday Change Percent -0.9598657
Fullday Price 34.05
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,790,812,800
Gross Margins 0.0
Has Pre Post Market Data 1
Held Percent Insiders 0.02566
Held Percent Institutions 0.8851
Implied Shares Outstanding 134,366,950
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Last Split Date 1,661,731,200
Last Split Factor 1:15
Long Business Summary Definium Therapeutics, Inc., a clinical biopharmaceutical company, develops novel product candidates to treat brain health disorders. The company's lead product candidates DT120, which is in phase 3 for the treatment of generalized anxiety disorder, major depressive disorder, and other brain health disorders; and DT402, a R-enantiomer of 3,4-methylenedioxymethamphetamine, which is in phase 2a clinical trials for the treatment of autism spectrum disorder. The company was formerly known as Mind Medicine (MindMed) Inc. and changed its name to Definium Therapeutics, Inc. in January 2026. Definium Therapeutics, Inc. is headquartered in New York, New York.
Long Name Definium Therapeutics, Inc.
Market us_market
Market Cap 4,619,535,872
Market State PRE
Max Age 86,400
Message Board Id finmb_631045282
Most Recent Quarter 1,782,777,600
Name Change Date 2,026-10-14
Net Income To Common -353,784,992
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 5,058,915,667
Number Of Analyst Opinions 18
Open 34.83
Operating Cashflow -167,951,008
Operating Margins 0.0
Overall Risk 4
Phone 212 220 6633
Pre Market Change -0.33000183
Pre Market Change Percent -0.9598657
Pre Market Price 34.05
Pre Market Time 1,791,981,663
Prev Name Mind Medicine (MindMed) Inc.
Previous Close 35.2
Price Eps Current Year -10.8067
Price Hint 2
Price To Book 5.0285215
Profit Margins 0.0
Quick Ratio 6.895
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.26316
Region US
Regular Market Change -0.82
Regular Market Change Percent -2.32954
Regular Market Day High 34.95
Regular Market Day Low 34.03
Regular Market Day Range 34.03 - 34.95
Regular Market Open 34.83
Regular Market Previous Close 35.2
Regular Market Price 34.38
Regular Market Time 1,791,921,601
Regular Market Volume 1,999,285
Return On Assets -0.20641
Return On Equity -0.64087
Sand P52 Week Change 0.17004645
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 2
Shares Outstanding 134,366,950
Shares Percent Shares Out 0.0844
Shares Short 11,344,959
Shares Short Previous Month Date 1,788,134,400
Shares Short Prior Month 9,836,400
Short Name Definium Therapeutics, Inc.
Short Percent Of Float 0.085
Short Ratio 4.8
Source Interval 15
State NY
Symbol DFTX
Target High Price 91.0
Target Low Price 55.0
Target Mean Price 72.33333
Target Median Price 71.0
Total Cash 1,083,879,040
Total Cash Per Share 8.067
Total Debt 36,467,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -3.43
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 28.19855
Two Hundred Day Average Change 6.181452
Two Hundred Day Average Change Percent 0.2192117
Type Disp Equity
Volume 1,999,285
Website https://definiumtx.com
Zip 10,007