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Day One Biopharmaceuticals, Inc. (DAWN)

Healthcare | Biotechnology | Brisbane, United States | NasdaqGS
21.48 USD +0.01 (0.047%) ⇧ (April 20, 2026, 4 p.m. EDT)

Short-term: ★★★★☆ | Long-term: ★★☆☆☆ | Dividends: ☆☆☆☆☆
Hot Take | April 19, 2026, 1:41 a.m. EDT

DAWN is a classic high-risk, high-reward 'merger story' trade. The stock has rallied 300%+ on the $2.5B Servier acquisition, trading at the exact 52-week high of $21.47. While the short-term technicals are bullish with coin contracts and 52-week highs providing a magnetic ceiling, the fundamentals remain broken: negative earnings, negative free cash flow, and a P/E that is undefined (forward earnings are also negative, though improving). As the price approaches $21.49, a sell-off toward the $17-20 range (50-day/200-day averages) is probable. Investable only for a speculative 'momentum kicker' prior to the merger close, not as a core holding.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
MSTL ✓0.334022
AutoARIMA0.335577
AutoETS0.335577
AutoTheta0.335961

Forecast horizon: 45 days | Selected: MSTL

Forecast Reliability
Score 34%
H-stat 29.10
Ljung-Box p 0.000
Jarque-Bera p 0.031
Excess Kurtosis -1.89
Attribute Value
Sector Healthcare
Debt to Equity Ratio 0.633
Revenue per Share 1.533
Market Cap 2,219,617,792
Forward P/E -502.93
Beta -1.75
Profit Margins -67.85%
Website https://dayonebio.com

As of April 19, 2026, 1:41 a.m. EDT: Options flow shows a distinct divergence in sentiment by expiration. Near-term April (expiring in 10 days) exhibits asymmetric positioning with massive call volume/interest (12 vol, 2.2k OI at 22 strike) compared to negligible put volume (389 vol, 15.1k OI), yet the Open Interest ratio heavily favors calls (OTM OI% 0.16 vs 0 for April Puts implies heavy call accumulation despite the high put volume metric which may reflect older positioning or specific large block trades). The price is trading near 52-week highs ($21.45), pricing in a major merger thesis. Mid-term (May/July) flows show heavy put volume (e.g., 150+ at $15 strike) against flat open interest, suggesting traders are using calls for exposure to the upside while hedging or betting on volatility, or potentially selling straddles given the high implied volatility (0.55 vs 0.06 for July). Essentially, speculators are positioning for upside momentum via near-term calls but maintaining defensive hedges via further-dated puts.


Info Dump

Attribute Value
52 Week Change 1.930423
Address1 1,800 Sierra Point Parkway
Address2 Suite 200
All Time High 28.699
All Time Low 5.44
Ask 27.5
Ask Size 2
Audit Risk 6
Average Analyst Rating 3.0 - Hold
Average Daily Volume10 Day 1,415,330
Average Daily Volume3 Month 4,011,091
Average Volume 4,011,091
Average Volume10Days 1,415,330
Beta -1.748
Bid 15.47
Bid Size 2
Board Risk 5
Book Value 4.284
City Brisbane
Compensation As Of Epoch Date 1,735,603,200
Compensation Risk 8
Country United States
Crypto Tradeable 0
Currency USD
Current Price 21.48
Current Ratio 8.015
Custom Price Alert Confidence HIGH
Date Short Interest 1,774,915,200
Day High 21.49
Day Low 21.48
Debt To Equity 0.633
Display Name Day One Biopharmaceuticals
Earnings Call Timestamp End 1,771,968,600
Earnings Call Timestamp Start 1,771,968,600
Earnings Timestamp 1,771,966,800
Earnings Timestamp End 1,778,011,200
Earnings Timestamp Start 1,778,011,200
Ebitda -124,274,000
Ebitda Margins -0.78564
Enterprise To Ebitda -14.327
Enterprise To Revenue 11.256
Enterprise Value 1,780,514,432
Eps Current Year -0.75506
Eps Forward -0.04271
Eps Trailing Twelve Months -1.04
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 17.6116
Fifty Day Average Change 3.8683987
Fifty Day Average Change Percent 0.2196506
Fifty Two Week Change Percent 193.0423
Fifty Two Week High 21.49
Fifty Two Week High Change -0.010000229
Fifty Two Week High Change Percent -0.00046534336
Fifty Two Week Low 5.635
Fifty Two Week Low Change 15.844999
Fifty Two Week Low Change Percent 2.8118896
Fifty Two Week Range 5.635 - 21.49
Financial Currency USD
First Trade Date Milliseconds 1,622,122,200,000
Float Shares 70,727,929
Forward Eps -0.04271
Forward P E -502.92673
Free Cashflow -61,958,752
Full Exchange Name NasdaqGS
Full Time Employees 178
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,775,001,600
Gross Margins 0.8912
Gross Profits 140,972,000
Has Pre Post Market Data 1
Held Percent Insiders 0.16861
Held Percent Institutions 0.85462
Implied Shares Outstanding 103,334,169
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Ipo Expected Date 2,021-05-27
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Day One Biopharmaceuticals, Inc., a commercial-stage biopharmaceutical company, engages in the identification, development, and commercialization of medicines for childhood and adult diseases with equal intensity in the United States. The company's lead product candidate is tovorafenib, an oral and brain-penetrant type II rapidly accelerated fibrosarcoma kinase inhibitor that is in Phase II clinical trial for pediatric patients with relapsed or refractory low-grade glioma; and Ipsen, a frontline raf-altered pLGG which is in Phase III clinical trial stage. It is also developing DAY301, a PTK7 targeted ADC composed of a novel humanized anti-PTK7 immunoglobulin G1 monoclonal antibody conjugated with a topoisomerase I inhibitor via a highly stable and hydrophilic modified valine-alanine (VA) cleavable linker for the treatment of patients with advanced solid tumors; and Emi-Le, an antibody-drug conjugate that targets B7- H4 conjugated to an auristatin anti-tubulin payload as a component of a proprietary linker-payload platform developed by Mersana Therapeutics that is in Phase 1 clinicla trial for the treatment of breast cancer, ovarian cancer, endometrial cancer, and adenoid cystic carcinoma (ACC). Day One Biopharmaceuticals, Inc. was incorporated in 2018 and is headquartered in Brisbane, California.
Long Name Day One Biopharmaceuticals, Inc.
Market us_market
Market Cap 2,219,617,792
Market State PRE
Max Age 86,400
Message Board Id finmb_704589075
Most Recent Quarter 1,767,139,200
Net Income To Common -107,322,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 2,220,651,291
Number Of Analyst Opinions 6
Open 21.49
Operating Cashflow -103,757,000
Operating Margins -0.51115
Overall Risk 7
Payout Ratio 0.0
Phone 650 484 0899
Pre Market Change 0.010000229
Pre Market Change Percent 0.046556
Pre Market Price 21.49
Pre Market Time 1,776,766,668
Previous Close 21.47
Price Eps Current Year -28.448069
Price Hint 2
Price To Book 5.0140057
Price To Sales Trailing12 Months 14.03205
Profit Margins -0.67847
Quick Ratio 7.73
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key hold
Recommendation Mean 3.0
Region US
Regular Market Change 0.01
Regular Market Change Percent 0.046578
Regular Market Day High 21.49
Regular Market Day Low 21.48
Regular Market Day Range 21.48 - 21.49
Regular Market Open 21.49
Regular Market Previous Close 21.47
Regular Market Price 21.48
Regular Market Time 1,776,715,201
Regular Market Volume 1,561,479
Return On Assets -0.14642
Return On Equity -0.2274
Revenue Growth 0.839
Revenue Per Share 1.533
Sand P52 Week Change 0.34445214
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 8
Shares Outstanding 103,334,169
Shares Percent Shares Out 0.0701
Shares Short 7,236,832
Shares Short Previous Month Date 1,772,150,400
Shares Short Prior Month 10,152,747
Short Name Day One Biopharmaceuticals, Inc
Short Percent Of Float 0.1033
Short Ratio 0.92
Source Interval 15
State CA
Symbol DAWN
Target High Price 21.5
Target Low Price 21.5
Target Mean Price 21.5
Target Median Price 21.5
Total Cash 441,112,992
Total Cash Per Share 4.27
Total Debt 2,793,000
Total Revenue 158,182,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -1.04
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 10.501075
Two Hundred Day Average Change 10.978925
Two Hundred Day Average Change Percent 1.0455048
Type Disp Equity
Volume 1,561,479
Website https://dayonebio.com
Zip 94,005