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Cue Biopharma, Inc. (CUE)

Healthcare | Biotechnology | Boston, United States | NasdaqCM
0.61 USD -0.01 (-1.463%) ⇩ (April 17, 2026, 4 p.m. EDT)
After hours: 0.61 +0.00 (0.049%) ⇧ (April 17, 2026, 7:54 p.m. EDT)

Short-term: ★★★☆☆ | Long-term: ★★☆☆☆ | Dividends: ★☆☆☆☆
Hot Take | April 19, 2026, midnight EDT

Despite a fundamentally valueless profile with negative earnings, gross margins, and a neutral dividend, CUE is positioned for a high-risk, high-reward trade driven entirely by Boehringer Ingelheim pipeline data. The retail sentiment is currently optimistic, supported by a 'strong buy' consensus despite the lack of tangible revenue generation. The options market is pricing in a massive upside move to $1.00+ based on this partnership, but this leaves the long-term investment thesis on shaky ground given the lack of operational cash flow, making it a pure 'knowledge plays' lottery ticket rather than a solid long-term asset.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoTheta ✓0.173234
AutoETS0.333459
AutoARIMA0.333464
MSTL0.339665

Forecast horizon: 45 days | Selected: AutoTheta

Forecast Reliability
Score 10%
H-stat 25.78
Ljung-Box p 0.000
Jarque-Bera p 0.000
Excess Kurtosis 5.83
Attribute Value
Sector Healthcare
Debt to Equity Ratio 15.878
Revenue per Share 0.29
Market Cap 59,201,972
Forward P/E -1.26
Beta 1.58
Profit Margins -96.85%
Website https://www.cuebiopharma.com

As of April 19, 2026, midnight EDT: Options activity is highly asymmetric and skewed toward calls. Call OI is concentrated heavily at the $1.00 strike (up to 2.6k contracts), implying a significant speculative distribution of directional bets for a 50% rise. However, the $1.00 strike represents deep Out-of-the-Money (OTM) territory relative to the current price of $0.61, suggesting this positioning is for a binary breakthrough or setup rather than immediate normalization. Put writing exists but is minimal compared to call exposure, indicating a bullish outlook based on expected R&D milestones (Boehringer Ingelheim data), despite a lack of immediate near-term catalysts priced in the OTM calls.


Info Dump

Attribute Value
52 Week Change -0.22407168
Address1 40 Guest Street
All Time High 31.69
All Time Low 0.166
Ask 0.6086
Ask Size 19
Audit Risk 8
Average Analyst Rating 1.0 - Strong Buy
Average Daily Volume10 Day 46,427,480
Average Daily Volume3 Month 8,787,645
Average Volume 8,787,645
Average Volume10Days 46,427,480
Beta 1.578
Bid 0.6061
Bid Size 2
Board Risk 7
Book Value 0.274
City Boston
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 6
Country United States
Crypto Tradeable 0
Currency USD
Current Price 0.6062
Current Ratio 2.741
Custom Price Alert Confidence HIGH
Date Short Interest 1,774,915,200
Day High 0.705
Day Low 0.5717
Debt To Equity 15.878
Display Name Cue Biopharma
Earnings Call Timestamp End 1,724,099,400
Earnings Call Timestamp Start 1,724,099,400
Earnings Timestamp End 1,755,547,200
Earnings Timestamp Start 1,755,028,800
Ebitda -25,563,000
Ebitda Margins -0.93071
Enterprise To Ebitda -1.376
Enterprise To Revenue 1.28
Enterprise Value 35,169,972
Eps Forward -0.48
Eps Trailing Twelve Months -0.28
Esg Populated 0
Exchange NCM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 0.31156
Fifty Day Average Change 0.29463997
Fifty Day Average Change Percent 0.94569254
Fifty Two Week Change Percent -22.407167
Fifty Two Week High 1.03
Fifty Two Week High Change -0.4238
Fifty Two Week High Change Percent -0.41145632
Fifty Two Week Low 0.166
Fifty Two Week Low Change 0.44019997
Fifty Two Week Low Change Percent 2.651807
Fifty Two Week Range 0.166 - 1.03
Financial Currency USD
First Trade Date Milliseconds 1,514,903,400,000
Float Shares 97,070,920
Forward Eps -0.48
Forward P E -1.2629167
Free Cashflow -9,951,750
Full Exchange Name NasdaqCM
Full Time Employees 29
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,775,001,600
Gross Margins -0.26859
Gross Profits -7,377,000
Has Pre Post Market Data 1
Held Percent Insiders 0.00565
Held Percent Institutions 0.22312
Implied Shares Outstanding 97,660,791
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Cue Biopharma, Inc., a clinical-stage biopharmaceutical company, develops a novel class of injectable therapeutics to selectively engage and modulate targeted, disease relevant T cells in the United States. Its lead drug product candidate is the CUE-401, a bifunctional fusion protein designed to promote immune tolerance by inducing iTregs from Teff cells which is in preclinical trial; and CUE-501, a treatment of autoimmune disease via anti-viral T cell-mediated depletion of B cells. The company also develops CUE-101, which is in phase 1b clinical trial to treat HPV+ recurrent metastatic, or head and neck squamous cell carcinoma in second line, and beyond patients as a monotherapy, as well as in phase 1b clinical trial for the treatment of head and neck squamous cell carcinoma as a first line, therapy in combination with standard of care KEYTRUDA; and CUE-102, which is in phase 1b clinical trial as a monotherapy in late line recurrent metastatic WT1+ colorectal, gastric, ovarian, and pancreatic cancer. It has collaboration agreements with LG Chem, Ltd. for the development of CUE-101 and CUE-102 Immuno-STATs; collaboration and option agreement with Ono Pharmaceutical Co., Ltd to development and commercialization rights for CUE-401; and license agreement with Albert Einstein College of Medicine. The company was formerly known as Imagen Biopharma, Inc. and changed its name to Cue Biopharma, Inc. in October 2016. Cue Biopharma, Inc. was incorporated in 2014 and is headquartered in Boston, Massachusetts.
Long Name Cue Biopharma, Inc.
Market us_market
Market Cap 59,201,972
Market State CLOSED
Max Age 86,400
Message Board Id finmb_417883814
Most Recent Quarter 1,767,139,200
Net Income To Common -26,602,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 59,201,971
Number Of Analyst Opinions 1
Open 0.64
Operating Cashflow -21,687,000
Operating Margins 0.08924
Overall Risk 6
Payout Ratio 0.0
Phone 617 949 2680
Post Market Change 0.00030004978
Post Market Change Percent 0.049496833
Post Market Price 0.6065
Post Market Time 1,776,470,065
Previous Close 0.6152
Price Hint 4
Price To Book 2.2124088
Price To Sales Trailing12 Months 2.155464
Profit Margins -0.96853995
Quick Ratio 2.644
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.0
Region US
Regular Market Change -0.009
Regular Market Change Percent -1.46294
Regular Market Day High 0.705
Regular Market Day Low 0.5717
Regular Market Day Range 0.5717 - 0.705
Regular Market Open 0.64
Regular Market Previous Close 0.6152
Regular Market Price 0.6062
Regular Market Time 1,776,456,001
Regular Market Volume 2,868,302
Return On Assets -0.44556
Return On Equity -1.2110801
Revenue Growth 12.923
Revenue Per Share 0.29
Sand P52 Week Change 0.38150132
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 4
Shares Outstanding 97,660,791
Shares Percent Shares Out 0.0273
Shares Short 2,664,499
Shares Short Previous Month Date 1,772,150,400
Shares Short Prior Month 1,781,535
Short Name Cue Biopharma, Inc.
Short Percent Of Float 0.0274
Short Ratio 1.15
Source Interval 15
State MA
Symbol CUE
Target High Price 4.0
Target Low Price 4.0
Target Mean Price 4.0
Target Median Price 4.0
Total Cash 28,229,000
Total Cash Per Share 0.289
Total Debt 4,197,000
Total Revenue 27,466,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -0.28
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 0.56114
Two Hundred Day Average Change 0.04505998
Two Hundred Day Average Change Percent 0.08030078
Type Disp Equity
Volume 2,868,302
Website https://www.cuebiopharma.com
Zip 2,135