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CytomX Therapeutics, Inc. (CTMX)

Healthcare | Biotechnology | South San Francisco, United States | NasdaqGS
4.82 USD -0.07 (-1.431%) ⇩ (April 17, 2026, 4 p.m. EDT)
After hours: 4.86 +0.04 (0.830%) ⇧ (April 17, 2026, 7:58 p.m. EDT)

Short-term: ★★☆☆☆ | Long-term: ★☆☆☆☆ | Dividends: ☆☆☆☆☆
Hot Take | April 11, 2026, 1:09 p.m. EDT

CTMX is a high-risk, high-reward biotechnology stock with a volatile price history and negative fundamentals. The recent news of positive trial progress and analyst upgrades may offer some short-term optimism, but the company's financials are weak, with negative earnings and a high debt-to-equity ratio. The stock is currently trading near its 52-week low, and while there are some positive developments, the long-term outlook remains uncertain. Investors should be cautious and consider the high risk involved.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoETS ✓0.174392
AutoARIMA0.174401
MSTL0.184069
AutoTheta0.206773

Forecast horizon: 45 days | Selected: AutoETS

Forecast Reliability
Score 42%
H-stat 16.39
Ljung-Box p 0.000
Jarque-Bera p 0.398
Excess Kurtosis -0.84
Attribute Value
Sector Healthcare
Debt to Equity Ratio 4.282
Revenue per Share 0.552
Market Cap 1,041,974,656
Forward P/E -10.19
Beta 2.48
Profit Margins -22.79%
Website https://www.cytomx.com

As of April 11, 2026, 1:09 p.m. EDT: Options speculators are showing mixed signals. There is significant open interest and volume in both calls and puts, with notable activity around strikes above the current price, suggesting some bullish sentiment. However, the presence of high open interest in puts, especially around lower strikes, indicates potential bearish positioning. The IV (implied volatility) is low across all expirations, suggesting limited expectations for large price swings in the near term. Overall, the options activity does not provide a clear directional signal but suggests a cautious approach.


Info Dump

Attribute Value
52 Week Change 5.52
Address1 151 Oyster Point Boulevard
Address2 Suite 400
All Time High 35.0
All Time Low 0.4
Ask 4.85
Ask Size 5
Audit Risk 4
Average Daily Volume10 Day 5,204,300
Average Daily Volume3 Month 6,903,588
Average Volume 6,903,588
Average Volume10Days 5,204,300
Beta 2.484
Bid 4.77
Bid Size 9
Board Risk 9
Book Value 0.582
City South San Francisco
Compensation As Of Epoch Date 1,735,603,200
Compensation Risk 8
Country United States
Crypto Tradeable 0
Currency USD
Current Price 4.82
Current Ratio 3.087
Custom Price Alert Confidence HIGH
Date Short Interest 1,774,915,200
Day High 5.0799
Day Low 4.8
Debt To Equity 4.282
Display Name CytomX Therapeutics
Earnings Call Timestamp End 1,773,662,400
Earnings Call Timestamp Start 1,773,662,400
Earnings Timestamp 1,773,664,200
Earnings Timestamp End 1,778,502,600
Earnings Timestamp Start 1,778,502,600
Ebitda -18,188,000
Ebitda Margins -0.23868
Enterprise To Ebitda -37.799
Enterprise To Revenue 9.022
Enterprise Value 687,488,128
Eps Current Year -0.41703
Eps Forward -0.47309
Eps Trailing Twelve Months -0.15
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fax 650 351 0353
Fifty Day Average 4.9648
Fifty Day Average Change -0.14479971
Fifty Day Average Change Percent -0.029165266
Fifty Two Week Change Percent 552.0
Fifty Two Week High 8.21
Fifty Two Week High Change -3.3899999
Fifty Two Week High Change Percent -0.41291106
Fifty Two Week Low 0.625
Fifty Two Week Low Change 4.195
Fifty Two Week Low Change Percent 6.7120004
Fifty Two Week Range 0.625 - 8.21
Financial Currency USD
First Trade Date Milliseconds 1,444,311,000,000
Float Shares 147,956,950
Forward Eps -0.47309
Forward P E -10.188336
Free Cashflow -43,208,500
Full Exchange Name NasdaqGS
Full Time Employees 69
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,775,001,600
Gross Margins 1.0
Gross Profits 76,201,000
Has Pre Post Market Data 1
Held Percent Insiders 0.00658
Held Percent Institutions 0.73129
Implied Shares Outstanding 216,177,309
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary CytomX Therapeutics, Inc. operates as an oncology-focused biopharmaceutical company that focuses on developing potent biologics designed to treat tumor microenvironment. The company utilizes conditional activation platform technology for oncology biologics research and development comprising the validation of targets for antibody-drug conjugates (ADCs), opening therapeutic window for novel T-cell engagers (TCEs) targeting solid tumors, and increasing the therapeutic index for immune modulators, such as cytokines; and PROBODY platform in preclinical research in areas outside of oncology. It also develops CX-904, a T-cell engaging bispecific antibody targeting the epidermal growth factor receptor (EGFR) on tumor cells and the CD3 receptor on T cells; CX-2051, a conditionally activated ADC for optimizing the therapeutic index for EpCAM-expressing epithelial cancers, including colorectal cancer; and CX-801, an interferon alpha-2b PROBODY cytokine. In addition, the company's development pipeline comprises CX-2029, a conditional activated ADC targeting CD71; and BMS-986288, a PROBODY version of non-fucosylated ipilimumab. It has strategic collaborations with Amgen, Astellas, Bristol Myers Squibb, Regeneron, and Moderna; and clinical trial collaboration and supply agreement with Merck for the evaluation of CX-801 in combination with anti-PD-1 therapy, KEYTRUDA (pembrolizumab). The company was founded in 2008 and is based in South San Francisco, California.
Long Name CytomX Therapeutics, Inc.
Market us_market
Market Cap 1,041,974,656
Market State CLOSED
Max Age 86,400
Message Board Id finmb_60504284
Most Recent Quarter 1,767,139,200
Net Income To Common -20,370,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 1,039,812,856
Number Of Analyst Opinions 9
Open 5.03
Operating Cashflow -75,587,000
Operating Margins -37.90649
Overall Risk 6
Payout Ratio 0.0
Phone 650 515 3185
Post Market Change 0.03999996
Post Market Change Percent 0.8298747
Post Market Price 4.86
Post Market Time 1,776,470,326
Previous Close 4.89
Price Eps Current Year -11.557921
Price Hint 4
Price To Book 8.281787
Price To Sales Trailing12 Months 13.674028
Profit Margins -0.22792
Quick Ratio 2.983
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key none
Region US
Regular Market Change -0.0699997
Regular Market Change Percent -1.43149
Regular Market Day High 5.0799
Regular Market Day Low 4.8
Regular Market Day Range 4.8 - 5.0799
Regular Market Open 5.03
Regular Market Previous Close 4.89
Regular Market Price 4.82
Regular Market Time 1,776,456,001
Regular Market Volume 4,936,386
Return On Assets -0.08988
Return On Equity -0.35246
Revenue Growth -0.983
Revenue Per Share 0.552
Sand P52 Week Change 0.36506534
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 3
Shares Outstanding 216,177,309
Shares Percent Shares Out 0.1019
Shares Short 22,031,153
Shares Short Previous Month Date 1,772,150,400
Shares Short Prior Month 18,864,576
Short Name CytomX Therapeutics, Inc.
Short Percent Of Float 0.10479999
Short Ratio 1.78
Source Interval 15
State CA
Symbol CTMX
Target High Price 17.0
Target Low Price 11.0
Target Mean Price 13.66667
Target Median Price 12.0
Total Cash 137,052,000
Total Cash Per Share 0.805
Total Debt 4,240,000
Total Revenue 76,201,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -0.15
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 3.729775
Two Hundred Day Average Change 1.0902252
Two Hundred Day Average Change Percent 0.2923032
Type Disp Equity
Volume 4,936,386
Website https://www.cytomx.com
Zip 94,080