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Castle Biosciences, Inc. (CSTL)

Healthcare | Diagnostics & Research | Friendswood, United States | NasdaqGM
22.98 USD -0.74 (-3.120%) ⇩ (July 13, 2026, 4 p.m. EDT)
After hours: 22.77 -0.21 (-0.210%) ⇩ (July 13, 2026, 7:47 p.m. EDT)

Short-term:★★⯪☆☆Long-term:★★⯪☆☆Dividends:☆☆☆☆☆
Hot Take | July 11, 2026, 4:42 a.m. EDT

The investment case for Castle Biosciences remains fundamentally broken despite a recent price bounce. The company is generating negative earnings and negative operating margins, with revenue contracting by nearly 5%. While the balance sheet appears healthy with substantial cash reserves, the business is failing to execute on growth, making it a poor candidate for long-term capital appreciation. The recent price action shows a recovery from multi-year lows, yet the underlying fundamentals—specifically the lack of profitability and shrinking top line—prevent a shift to a 'buy' rating. The options market confirms this tension: traders are buying deep out-of-the-money calls for a moonshot scenario while hedging against a drop to much lower levels, rather than betting on a steady climb. With no dividend to provide income and a weak statistical forecast, the security sits in a neutral zone where the risk of further deterioration outweighs the potential for a turnaround.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
MSTL ✓0.117860
AutoARIMA0.133351
AutoETS0.134715
AutoTheta0.137570

Forecast horizon: 45 days | Selected: MSTL

Forecast Reliability
Score 43%
H-stat 0.23
Ljung-Box p 0.000
Jarque-Bera p 0.328
Excess Kurtosis -0.93
Attribute Value
Sector Healthcare
Debt to Equity Ratio 7.959
Revenue per Share 11.599
Market Cap 696,982,272
Forward P/E -24.62
Beta 1.00
Profit Margins -3.78%
Website https://castlebiosciences.com

As of July 11, 2026, 4:42 a.m. EDT: Speculators are positioning defensively with heavy put volume at strikes significantly below the current price (15 and 20), suggesting a fear of a downside gap or continued weakness. Conversely, call interest is concentrated far out-of-the-money (55 and 60 strikes), indicating a speculative bet on a massive, unlikely surge rather than a measured rally. Implied volatility is elevated on near-term puts, reflecting uncertainty about immediate support levels.


Info Dump

Attribute Value
52 Week Change 0.21641028
Address1 1,500 W. Parkwood Ave
Address2 Suite 400
All Time High 107.69
All Time Low 9.26
Ask 28.85
Ask Size 2
Audit Risk 3
Average Analyst Rating 1.0 - Strong Buy
Average Daily Volume10 Day 352,500
Average Daily Volume3 Month 396,324
Average Volume 396,324
Average Volume10Days 352,500
Beta 0.996
Bid 16.65
Bid Size 2
Board Risk 6
Book Value 15.23
City Friendswood
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 7
Country United States
Crypto Tradeable 0
Currency USD
Current Price 22.98
Current Ratio 6.745
Custom Price Alert Confidence HIGH
Date Short Interest 1,782,777,600
Day High 23.875
Day Low 22.46
Debt To Equity 7.959
Display Name Castle Biosciences
Earnings Call Timestamp End 1,785,441,600
Earnings Call Timestamp Start 1,785,441,600
Earnings Timestamp 1,785,441,600
Earnings Timestamp End 1,785,441,600
Earnings Timestamp Start 1,785,441,600
Ebitda -18,353,000
Ebitda Margins -0.053990003
Enterprise To Ebitda -25.719
Enterprise To Revenue 1.389
Enterprise Value 472,021,312
Eps Current Year -1.40444
Eps Forward -0.93333
Eps Trailing Twelve Months -0.42
Esg Populated 0
Exchange NGM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 21.6742
Fifty Day Average Change 1.3057995
Fifty Day Average Change Percent 0.06024672
Fifty Two Week Change Percent 21.641027
Fifty Two Week High 44.28
Fifty Two Week High Change -21.3
Fifty Two Week High Change Percent -0.4810298
Fifty Two Week Low 14.59
Fifty Two Week Low Change 8.389999
Fifty Two Week Low Change Percent 0.57505137
Fifty Two Week Range 14.59 - 44.28
Financial Currency USD
First Trade Date Milliseconds 1,564,061,400,000
Float Shares 26,790,143
Forward Eps -0.93333
Forward P E -24.621515
Free Cashflow 12,890,500
Full Exchange Name NasdaqGM
Full Time Employees 942
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,782,864,000
Gross Margins 0.77884
Gross Profits 264,742,000
Has Pre Post Market Data 1
Held Percent Insiders 0.02728
Held Percent Institutions 0.92401004
Implied Shares Outstanding 30,329,952
Industry Diagnostics & Research
Industry Disp Diagnostics & Research
Industry Key diagnostics-research
Is Earnings Date Estimate 0
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Castle Biosciences, Inc., a molecular diagnostics company, provides test solutions for the diagnosis and treatment of dermatologic cancers, Barrett's esophagus (BE), atopic dermatitis (AD), and uveal melanoma. The company offers DecisionDx-Melanoma, a risk stratification gene expression profile (GEP) test that predicts the likelihood of a positive sentinel lymph node and the risk of metastasis for patients with invasive cutaneous melanoma; TissueCypher, a risk stratification spatialomics test to predict future development of high-grade dysplasia and/or esophageal cancer in patients with non-dysplastic, indefinite dysplasia, and low-grade dysplasia BE; AdvanceAD-Tx, a non-invasive GEP test which is designed to guide systemic treatment selection for patients aged 12 years and older with moderateto-severe AD; DecisionDx-SCC, a GEP test for cutaneous squamous cell carcinoma; and MyPath Melanoma, a diagnostic GEP test for use in patients with difficult-to-diagnose melanocytic lesions. It also provides DecisionDx-UM, a risk stratification GEP test that predicts the risk of metastasis for patients with uveal melanoma. The company offers its products to dermatology and gastroenterology markets. The company was incorporated in 2007 and is headquartered in Friendswood, Texas.
Long Name Castle Biosciences, Inc.
Market us_market
Market Cap 696,982,272
Market State POSTPOST
Max Age 86,400
Message Board Id finmb_60295846
Most Recent Quarter 1,774,915,200
Net Income To Common -12,832,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 719,426,461
Number Of Analyst Opinions 9
Open 23.785
Operating Cashflow 48,254,000
Operating Margins -0.21997
Overall Risk 6
Payout Ratio 0.0
Phone 866 788 9007
Post Market Change -0.20999908
Post Market Change Percent -0.91383415
Post Market Price 22.77
Post Market Time 1,783,986,470
Previous Close 23.72
Price Eps Current Year -16.362392
Price Hint 2
Price To Book 1.508864
Price To Sales Trailing12 Months 2.0504303
Profit Margins -0.037750002
Quick Ratio 6.26
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.0
Region US
Regular Market Change -0.74
Regular Market Change Percent -3.11973
Regular Market Day High 23.875
Regular Market Day Low 22.46
Regular Market Day Range 22.46 - 23.875
Regular Market Open 23.785
Regular Market Previous Close 23.72
Regular Market Price 22.98
Regular Market Time 1,783,972,801
Regular Market Volume 269,897
Return On Assets -0.03965
Return On Equity -0.02846
Revenue Growth -0.049
Revenue Per Share 11.599
Sand P52 Week Change 0.20847368
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 8
Shares Outstanding 30,329,952
Shares Percent Shares Out 0.049200002
Shares Short 1,491,750
Shares Short Previous Month Date 1,780,012,800
Shares Short Prior Month 1,484,771
Short Name Castle Biosciences, Inc.
Short Percent Of Float 0.0504
Short Ratio 3.95
Source Interval 15
State TX
Symbol CSTL
Target High Price 52.0
Target Low Price 35.0
Target Mean Price 43.55556
Target Median Price 43.0
Total Cash 261,684,992
Total Cash Per Share 8.628
Total Debt 36,724,000
Total Revenue 339,920,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -0.42
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 28.73835
Two Hundred Day Average Change -5.7583504
Two Hundred Day Average Change Percent -0.20037164
Type Disp Equity
Volume 269,897
Website https://castlebiosciences.com
Zip 77,546