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CRISPR Therapeutics AG (CRSP)

Healthcare | Biotechnology | Zug, Switzerland | NasdaqGM
51.52 USD +1.30 (2.589%) ⇧ (Oct. 15, 2026, 4 p.m. EDT)

Short-term:★★⯪☆☆Long-term:★★⯪☆☆Dividends:☆☆☆☆☆
Hot Take ↕ | Oct. 10, 2026, 3:49 a.m. EDT

The long-term outlook remains neutral due to the company's status as a cash-burning biotech firm with no dividend and negative earnings, despite a recent year-over-year price surge. The business faces significant execution risk, and the lack of sustained profitability prevents a 'buy-and-hold' recommendation regardless of the recent price recovery. In the short term, the stock is a volatile speculation driven entirely by options flow targeting specific catalyst events. Traders are buying deep out-of-the-money calls for a moonshot move while holding protective puts nearby, creating a choppy trading environment where the statistical forecast offers no guidance. The disconnect between the high analyst target price and the negative fundamentals suggests the market is pricing in a potential miracle cure, but the current data supports a cautious stance.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoTheta ✓0.045060
AutoETS0.045165
AutoARIMA0.045178
MSTL0.048851

Forecast horizon: 45 days | Selected: AutoTheta

Forecast Reliability
Score 42%
H-stat 0.50
Ljung-Box p 0.000
Jarque-Bera p 0.546
Excess Kurtosis -0.79
Attribute Value
Sector Healthcare
Debt to Equity Ratio 44.874
Revenue per Share 0.141
Market Cap 4,981,605,888
Forward P/E -14.50
Beta 1.76
Website https://www.crisprtx.com

As of Oct. 10, 2026, 3:49 a.m. EDT: Speculators are positioning for volatility rather than a clear directional breakout. Call volume is heavily skewed toward out-of-the-money strikes (60, 65, 75), indicating a speculative bet on a sharp rally, while put open interest clusters tightly around the current price (52-55), acting as a defensive floor. The massive implied volatility spikes at distant strikes suggest the market is pricing in binary event risk (clinical trial results or regulatory milestones) rather than steady price appreciation.


Info Dump

Attribute Value
52 Week Change -0.25495303
Address1 Baarerstrasse 14
All Time High 220.2
All Time Low 11.63
Ask 67.84
Ask Size 2
Audit Risk 8
Average Analyst Rating 2.1 - Buy
Average Daily Volume10 Day 1,696,080
Average Daily Volume3 Month 1,581,315
Average Volume 1,581,315
Average Volume10Days 1,696,080
Beta 1.759
Bid 44.5
Bid Size 1
Board Risk 8
Book Value 18.069
City Zug
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 10
Country Switzerland
Crypto Tradeable 0
Currency USD
Current Price 51.52
Current Ratio 17.847
Custom Price Alert Confidence HIGH
Date Short Interest 1,790,726,400
Day High 52.3725
Day Low 49.76
Debt To Equity 44.874
Display Name CRISPR Therapeutics
Dividend Yield 0.0
Earnings Timestamp 1,785,787,200
Earnings Timestamp End 1,794,254,400
Earnings Timestamp Start 1,794,254,400
Ebitda -513,174,016
Ebitda Margins 0.0
Enterprise To Ebitda -6.627
Enterprise To Revenue 253.958
Enterprise Value 3,401,001,472
Eps Current Year -4.4468
Eps Forward -3.55405
Eps Trailing Twelve Months -4.74
Esg Populated 0
Exchange NGM
Exchange Data Delayed By 15
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 54.9916
Fifty Day Average Change -3.4715996
Fifty Day Average Change Percent -0.06312963
Fifty Two Week Change Percent -25.495302
Fifty Two Week High 75.06
Fifty Two Week High Change -23.539997
Fifty Two Week High Change Percent -0.31361574
Fifty Two Week Low 44.12
Fifty Two Week Low Change 7.4000015
Fifty Two Week Low Change Percent 0.16772443
Fifty Two Week Range 44.12 - 75.06
Financial Currency USD
First Trade Date Milliseconds 1,476,883,800,000
Float Shares 96,257,536
Forward Eps -3.55405
Forward P E -14.496139
Free Cashflow -215,845,872
Full Exchange Name NasdaqGM
Fullday Change 0.40999985
Fullday Change Percent 0.7958071
Fullday Price 51.93
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,790,812,800
Gross Margins 0.0
Gross Profits -461,800,992
Has Pre Post Market Data 1
Held Percent Insiders 0.0589
Held Percent Institutions 0.78218
Implied Shares Outstanding 96,692,653
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary CRISPR Therapeutics AG, a gene editing company, focuses on developing gene-based medicines for serious human diseases using its Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) platform. The company's CRISPR/Cas9 is a technology for gene editing which is the process of precisely altering specific sequences of genomic DNA. It has a portfolio of therapeutic programs across a range of disease areas, including hemoglobinopathies, CAR T cell therapies, in vivo, and type 1 diabetes, as well as develops investigational CAR T programs, including an autologous, gene-edited CAR T program targeting allogeneic chimeric antigen receptor T cell for autoimmune indications and oncology. The company's lead product candidate is CASGEVY, an ex vivo CRISPR/Cas9 gene-edited cell therapy for treating patients suffering from transfusion-dependent beta-thalassemia, severe sickle cell disease (SCD), and hemoglobinopathies in which a patient's hematopoietic stem and progenitor cells are edited to produce high levels of fetal hemoglobin in red blood cells. It also develops CAR T cell therapies, including CTX112 targeting cluster of differentiation 19 (CD19) and CTX131 targeting CD70 for oncology and autoimmune indications; CTX310 and CTX320, in vivo gene editing to address the cardiovascular disease by disrupting the validated targets angiopoietin-like protein 3 and lipoprotein; and CTX211, an allogeneic, gene-edited, hypoimmune stem cell-derived product candidate for the treatment of T1D. It has strategic partnerships with Vertex Pharmaceuticals Incorporated. CRISPR Therapeutics AG was incorporated in 2013 and is headquartered in Zug, Switzerland.
Long Name CRISPR Therapeutics AG
Market us_market
Market Cap 4,981,605,888
Market State PRE
Max Age 86,400
Message Board Id finmb_262549448
Most Recent Quarter 1,782,777,600
Net Income To Common -451,139,008
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 5,391,582,331
Number Of Analyst Opinions 19
Open 49.98
Operating Cashflow -369,582,016
Operating Margins -11.27551
Overall Risk 9
Payout Ratio 0.0
Phone 41 41 561 32 77
Pre Market Change 0.40999985
Pre Market Change Percent 0.7958071
Pre Market Price 51.93
Pre Market Time 1,792,152,928
Previous Close 50.22
Price Eps Current Year -11.585859
Price Hint 2
Price To Book 2.8512924
Price To Sales Trailing12 Months 371.9837
Profit Margins 0.0
Quick Ratio 17.791
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key buy
Recommendation Mean 2.08696
Region US
Regular Market Change 1.3
Regular Market Change Percent 2.58861
Regular Market Day High 52.3725
Regular Market Day Low 49.76
Regular Market Day Range 49.76 - 52.3725
Regular Market Open 49.98
Regular Market Previous Close 50.22
Regular Market Price 51.52
Regular Market Time 1,792,094,401
Regular Market Volume 1,351,476
Return On Assets -0.14204
Return On Equity -0.26095
Revenue Growth 10.414
Revenue Per Share 0.141
Sand P52 Week Change 0.16207206
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 2
Shares Outstanding 96,692,653
Shares Percent Shares Out 0.19319999
Shares Short 18,679,198
Shares Short Previous Month Date 1,788,134,400
Shares Short Prior Month 18,769,995
Short Name CRISPR Therapeutics AG
Short Percent Of Float 0.2212
Short Ratio 11.76
Source Interval 15
Symbol CRSP
Target High Price 291.0
Target Low Price 44.0
Target Mean Price 85.63158
Target Median Price 80.0
Total Cash 2,364,352,000
Total Cash Per Share 24.452
Total Debt 783,747,968
Total Revenue 13,392,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -4.74
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 53.132076
Two Hundred Day Average Change -1.6120758
Two Hundred Day Average Change Percent -0.030340916
Type Disp Equity
Volume 1,351,476
Website https://www.crisprtx.com
Zip 6,300