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Cardiff Oncology, Inc. (CRDF)

Healthcare | Biotechnology | San Diego, United States | NasdaqCM
0.96 USD -0.01 (-1.535%) ⇩ (Oct. 16, 2026, 11:47 a.m. EDT)

Short-term:★★☆☆☆Long-term:★☆☆☆☆Dividends:☆☆☆☆☆
Hot Take ↕ | Oct. 10, 2026, 3:16 a.m. EDT

The investment case for Cardiff Oncology is defined by a stark disconnect between its deteriorating business reality and speculative hopes for a clinical breakthrough. Fundamentally, the company is in distress: revenue has contracted by 14%, operating margins are catastrophic at -92%, and the stock has lost 99% of its value over the last nine years. The balance sheet is fragile, with massive free cash burn and negative returns on equity, leaving no safety net if the pipeline fails. While insider buying and a recent $10 million capital raise provide a temporary lifeline, these actions do not alter the structural decline evident in the price history. However, the options market tells a different story, positioning aggressively for a rally. The heavy concentration of call open interest at strikes significantly above the current price suggests traders are betting on a successful Phase II trial result or a strategic partnership announcement that could re-rate the entire asset. This speculative fervor creates a volatile, binary trading environment rather than a stable investment thesis. For the long term, the risk of permanent capital loss remains high given the lack of commercialized products and shrinking revenues. Short-term, the stock acts as a leveraged bet on a single clinical event, making it suitable only for high-risk speculation, not portfolio allocation.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
MSTL ✓0.201192
AutoETS0.212543
AutoARIMA0.213212
AutoTheta0.565809

Forecast horizon: 45 days | Selected: MSTL

Forecast Reliability
Score 30%
H-stat 12.07
Ljung-Box p 0.000
Jarque-Bera p 0.233
Excess Kurtosis -0.94
Attribute Value
Sector Healthcare
Debt to Equity Ratio 1.722
Revenue per Share 0.007
Market Cap 74,380,032
Forward P/E -1.79
Beta 1.42
Website https://www.cardiffoncology.com

As of Oct. 10, 2026, 3:16 a.m. EDT: Options activity reveals a distinct bullish bias with heavy open interest in out-of-the-money calls (strikes $1.50 and $2.50) across multiple expirations, suggesting speculation on a significant upside move. Conversely, put volume is negligible and concentrated near the money, indicating minimal hedging against downside. Implied volatility is extremely low, reflecting a lack of pricing for a crash despite the company's precarious fundamentals.


Info Dump

Attribute Value
52 Week Change -0.55707765
Address1 11,055 Flintkote Avenue
All Time High 2,030.4
All Time Low 0.7
Ask 1.02
Ask Size 1
Audit Risk 6
Average Daily Volume10 Day 450,900
Average Daily Volume3 Month 798,423
Average Volume 798,423
Average Volume10Days 450,900
Beta 1.418
Bid 1.11
Bid Size 3
Board Risk 2
Book Value 0.387
City San Diego
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 8
Country United States
Crypto Tradeable 0
Currency USD
Current Price 0.9561
Current Ratio 3.296
Custom Price Alert Confidence HIGH
Date Short Interest 1,790,726,400
Day High 0.9949
Day Low 0.9501
Debt To Equity 1.722
Display Name Cardiff Oncology
Dividend Date 1,550,620,800
Dividend Yield 0.0
Earnings Call Timestamp End 1,740,691,800
Earnings Call Timestamp Start 1,740,691,800
Earnings Timestamp 1,786,478,400
Earnings Timestamp End 1,794,513,600
Earnings Timestamp Start 1,794,513,600
Ebitda -41,915,000
Ebitda Margins 0.0
Enterprise To Ebitda -0.99
Enterprise To Revenue 81.646
Enterprise Value 41,476,188
Eps Current Year -0.5625
Eps Forward -0.535
Eps Trailing Twelve Months -0.6
Esg Populated 0
Exchange NCM
Exchange Data Delayed By 15
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 1.094
Fifty Day Average Change -0.1379
Fifty Day Average Change Percent -0.12605119
Fifty Two Week Change Percent -55.707764
Fifty Two Week High 3.31
Fifty Two Week High Change -2.3539
Fifty Two Week High Change Percent -0.711148
Fifty Two Week Low 0.76
Fifty Two Week Low Change 0.1961
Fifty Two Week Low Change Percent 0.2580263
Fifty Two Week Range 0.76 - 3.31
Financial Currency USD
First Trade Date Milliseconds 1,090,935,000,000
Float Shares 75,379,707
Forward Eps -0.535
Forward P E -1.7871027
Free Cashflow -24,304,250
Full Exchange Name NasdaqCM
Full Time Employees 30
Fullday Change -0.014900029
Fullday Change Percent -1.5345035
Fullday Price 0.9561
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,790,812,800
Gross Margins 0.0
Gross Profits -34,821,000
Has Pre Post Market Data 1
Held Percent Insiders 0.06204
Held Percent Institutions 0.22114
Implied Shares Outstanding 77,795,249
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Last Split Date 1,550,620,800
Last Split Factor 1:6
Long Business Summary Cardiff Oncology, Inc., a clinical-stage biotechnology company, develops novel therapies for the treatment of various cancers in the United States. Its lead drug candidate is Onvansertib, an oral and selective polo-like kinase 1 inhibitor for treating RAS-mutated metastatic colorectal cancer. The company also focuses on the clinical program in indications, such as investigator-initiated trials in metastatic pancreatic ductal adenocarcinoma, small cell lung cancer, metastatic triple negative breast cancer, and chronic myelomonocytic leukemia; CRDF-004, a Phase 2 open-label randomized multi-center clinical trial of onvansertib in combination with FOLFIRI and bevacizumab or FOLFOX and bevacizumab for the treatment of patients confirmed metastatic and unresectable colorectal cancer in patients with a KRAS or NRAS mutation; and TROV-054, a Phase 1b/2 single-arm clinical trial in KRAS-mutated metastatic colorectal cancer. The company was formerly known as Trovagene, Inc. and changed its name to Cardiff Oncology, Inc. in May 2012. Cardiff Oncology, Inc. was founded in 1999 and is headquartered in San Diego, California.
Long Name Cardiff Oncology, Inc.
Market us_market
Market Cap 74,380,032
Market State REGULAR
Max Age 86,400
Message Board Id finmb_10959548
Most Recent Quarter 1,782,777,600
Net Income To Common -40,076,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 103,467,681
Number Of Analyst Opinions 7
Open 0.98
Operating Cashflow -40,854,000
Operating Margins -92.45193
Overall Risk 4
Phone 858 952 7570
Previous Close 0.971
Price Eps Current Year -1.6997333
Price Hint 4
Price To Book 2.4705427
Price To Sales Trailing12 Months 146.41739
Profit Margins 0.0
Quick Ratio 3.215
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key none
Region US
Regular Market Change -0.014900029
Regular Market Change Percent -1.5345035
Regular Market Day High 0.9949
Regular Market Day Low 0.9501
Regular Market Day Range 0.9501 - 0.9949
Regular Market Open 0.98
Regular Market Previous Close 0.971
Regular Market Price 0.9561
Regular Market Time 1,792,165,664
Regular Market Volume 130,672
Return On Assets -0.46726
Return On Equity -0.94085
Revenue Growth -0.141
Revenue Per Share 0.007
Sand P52 Week Change 0.16207206
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 3
Shares Outstanding 77,795,249
Shares Percent Shares Out 0.1552
Shares Short 12,073,948
Shares Short Previous Month Date 1,788,134,400
Shares Short Prior Month 11,684,625
Short Name Cardiff Oncology, Inc.
Short Percent Of Float 0.1585
Short Ratio 14.24
Source Interval 15
State CA
Symbol CRDF
Target High Price 12.0
Target Low Price 1.2
Target Mean Price 5.81429
Target Median Price 6.0
Total Cash 34,520,000
Total Cash Per Share 0.444
Total Debt 457,000
Total Revenue 508,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -0.6
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 1.54855
Two Hundred Day Average Change -0.59245
Two Hundred Day Average Change Percent -0.3825837
Type Disp Equity
Volume 130,672
Website https://www.cardiffoncology.com
Zip 92,121