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Caribou Biosciences, Inc. (CRBU)

Healthcare | Biotechnology | Berkeley, United States | NasdaqGS
1.80 USD -0.13 (-6.494%) ⇩ (July 13, 2026, 4 p.m. EDT)
After hours: 1.83 +0.03 (1.633%) ⇧ (July 13, 2026, 7:20 p.m. EDT)

Short-term:★★⯪☆☆Long-term:★☆☆☆☆Dividends:☆☆☆☆☆
Hot Take | July 11, 2026, 3:20 a.m. EDT

The fundamental reality here is stark: despite a 'strong buy' analyst consensus driven by a $32 price target, the business is deteriorating. Revenue growth is negligible at 1.9%, while the company burns cash aggressively, resulting in a -10.9% operating margin and negative free cash flow. The balance sheet is fragile with negative ROE and ROA, and the stock has suffered a catastrophic -90% decline over the last four years. The recent price action shows a slight recovery from lows, but the technicals remain weak relative to the 200-day average. The disconnect between the analyst targets and the actual financials is dangerous. Analysts are pricing in a miracle turnaround that the current fundamentals do not support. The options market reflects this tension: while call buyers are optimistic about a breakout, the extreme put IV suggests the market is terrified of a continued grind lower. For a biotech stock with no dividends and a history of multi-year destruction, the risk-reward profile is unfavorable. The 'strong buy' rating appears to be a function of the low share price making the absolute dollar gain look large, rather than a reflection of superior business quality.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoTheta ✓0.090856
MSTL_62_1130.096692
MSTL_1130.100524
MSTL_620.111758
AutoETS0.113846
AutoARIMA0.113849
MSTL0.120102

Forecast horizon: 60 days | Selected: AutoTheta

Forecast Reliability
Score 32%
H-stat 5.24
Ljung-Box p 0.000
Jarque-Bera p 0.544
Excess Kurtosis -0.69
Attribute Value
Sector Healthcare
Debt to Equity Ratio 26.413
Revenue per Share 0.119
Market Cap 178,525,040
Forward P/E -1.29
Beta 2.37
Website https://cariboubio.com

As of July 11, 2026, 3:20 a.m. EDT: Speculators are heavily skewed toward calls, with open interest concentrated in out-of-the-money strikes ($2.50 and $5.00) across various expirations, suggesting a speculative bet on a binary event or pipeline catalyst. However, implied volatility is significantly elevated for puts (2.92% vs 0.70% for calls), indicating deep fear regarding downside protection. The massive put volume at the $2.50 strike suggests a specific resistance level where traders are hedging against a failure to break out, creating a 'long gamma' squeeze scenario if the price rallies, but a heavy ceiling if it stalls.


Info Dump

Attribute Value
52 Week Change 0.13235295
Address1 2,929 7th Street
Address2 Suite 105
All Time High 32.645
All Time Low 0.66
Ask 2.26
Ask Size 2
Average Analyst Rating 1.1 - Strong Buy
Average Daily Volume10 Day 3,471,290
Average Daily Volume3 Month 2,065,173
Average Volume 2,065,173
Average Volume10Days 3,471,290
Beta 2.365
Bid 1.34
Bid Size 2
Book Value 1.052
City Berkeley
Compensation As Of Epoch Date 1,767,139,200
Country United States
Crypto Tradeable 0
Currency USD
Current Price 1.8
Current Ratio 6.221
Custom Price Alert Confidence HIGH
Date Short Interest 1,782,777,600
Day High 1.91
Day Low 1.76
Debt To Equity 26.413
Display Name Caribou Biosciences
Earnings Timestamp End 1,778,184,000
Earnings Timestamp Start 1,778,184,000
Ebitda -114,156,000
Ebitda Margins 0.0
Enterprise To Ebitda -0.77
Enterprise To Revenue 7.841
Enterprise Value 87,845,032
Eps Current Year -1.24667
Eps Forward -1.4
Eps Trailing Twelve Months -1.42
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 1.9195
Fifty Day Average Change -0.11950004
Fifty Day Average Change Percent -0.06225582
Fifty Two Week Change Percent 13.235294
Fifty Two Week High 3.535
Fifty Two Week High Change -1.7350001
Fifty Two Week High Change Percent -0.49080625
Fifty Two Week Low 1.38
Fifty Two Week Low Change 0.41999996
Fifty Two Week Low Change Percent 0.30434778
Fifty Two Week Range 1.38 - 3.535
Financial Currency USD
First Trade Date Milliseconds 1,627,047,000,000
Float Shares 94,810,679
Forward Eps -1.4
Forward P E -1.2857143
Free Cashflow -63,509,124
Full Exchange Name NasdaqGS
Full Time Employees 97
Gmt Off Set Milliseconds -14,400,000
Gross Margins 0.0
Gross Profits -81,400,000
Has Pre Post Market Data 1
Held Percent Insiders 0.08912
Held Percent Institutions 0.37747002
Implied Shares Outstanding 99,180,575
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Ipo Expected Date 2,021-07-23
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Caribou Biosciences, Inc. operates as a clinical-stage clustered regularly interspaced short palindromic repeats (CRISPR) genome-editing biopharmaceutical company. It offers a genome-editing platform based on novel CRISPR hybrid RNA-DNA genome-editing technology that enables precise genome editing of allogeneic cell therapies. The company develops Vispacabtagene Regedleucel, an allogeneic anti-CD19 CAR-T cell therapy that is in phase 1 clinical trial to treat relapsed or refractory B cell non-Hodgkin lymphoma; and CB-011, an allogeneic anti-BCMA CAR-T cell therapy that is in phase 1 clinical trial for the treatment of relapsed or refractory multiple myeloma. Caribou Biosciences, Inc. was incorporated in 2011 and is headquartered in Berkeley, California.
Long Name Caribou Biosciences, Inc.
Market us_market
Market Cap 178,525,040
Market State PREPRE
Max Age 86,400
Message Board Id finmb_272189231
Most Recent Quarter 1,774,915,200
Net Income To Common -133,219,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 190,922,606
Number Of Analyst Opinions 7
Open 1.9
Operating Cashflow -101,251,000
Operating Margins -10.9637
Payout Ratio 0.0
Phone 510 982 6030
Post Market Change 0.029399991
Post Market Change Percent 1.6333328
Post Market Price 1.8294
Post Market Time 1,783,984,822
Previous Close 1.925
Price Eps Current Year -1.4438463
Price Hint 4
Price To Book 1.7110265
Price To Sales Trailing12 Months 15.935468
Profit Margins 0.0
Quick Ratio 6.099
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.14286
Region US
Regular Market Change -0.125
Regular Market Change Percent -6.49351
Regular Market Day High 1.91
Regular Market Day Low 1.76
Regular Market Day Range 1.76 - 1.91
Regular Market Open 1.9
Regular Market Previous Close 1.925
Regular Market Price 1.8
Regular Market Time 1,783,972,801
Regular Market Volume 1,954,826
Return On Assets -0.34687
Return On Equity -0.8346
Revenue Growth 0.019
Revenue Per Share 0.119
Sand P52 Week Change 0.20847368
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 99,180,575
Shares Percent Shares Out 0.0971
Shares Short 9,625,837
Shares Short Previous Month Date 1,780,012,800
Shares Short Prior Month 7,450,323
Short Name Caribou Biosciences, Inc.
Short Percent Of Float 0.1011
Short Ratio 3.88
Source Interval 15
State CA
Symbol CRBU
Target High Price 32.0
Target Low Price 4.0
Target Mean Price 12.0
Target Median Price 10.0
Total Cash 117,626,000
Total Cash Per Share 1.186
Total Debt 26,946,000
Total Revenue 11,203,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -1.42
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 1.9369
Two Hundred Day Average Change -0.13690007
Two Hundred Day Average Change Percent -0.070679985
Type Disp Equity
Volume 1,954,826
Website https://cariboubio.com
Zip 94,710