Caribou Biosciences, Inc. (CRBU)Healthcare | Biotechnology | Berkeley, United States | NasdaqGS
1.62 USD
-0.04
(-2.410%) ⇩
(Aug. 28, 2026, 4 p.m.
EDT)
After hours: 1.65 +0.03 (1.852%) ⇧ (Aug. 28, 2026, 7:30 p.m. EDT) |
Hot Take ↕ | Aug. 22, 2026, 2:15 a.m. EDT
The investment case here is fundamentally broken. This biotech stock has suffered a catastrophic multi-year decline, dropping nearly 94% over the last four years with every single year showing negative returns. The company is burning cash aggressively, reporting negative free cash flow and operating cash flow, while revenue has contracted significantly. Despite a 'strong buy' analyst rating and a lofty $32 price target, these metrics reflect a speculative bet on a future cure rather than a viable business today; the market has correctly priced the high risk of total capital loss. The balance sheet, while currently liquid, cannot sustain this burn rate indefinitely without dilution or a successful clinical trial. Short-term, the stock is trapped between the $1.50 support and the heavy put wall at $2.00, likely to remain range-bound or drift lower until a binary event occurs. There is no margin of safety here, only a lottery ticket with a very low probability of success. |
| Model | MAE |
|---|---|
| AutoETS ✓ | 0.168166 |
| MSTL | 0.182982 |
| AutoARIMA | 0.189356 |
| AutoTheta | 0.193283 |
Forecast horizon: 45 days | Selected: AutoETS
| Forecast Reliability | |
|---|---|
| Score | 41% |
| H-stat | 2.11 |
| Ljung-Box p | 0.000 |
| Jarque-Bera p | 0.564 |
| Excess Kurtosis | -0.35 |
| Attribute | Value |
|---|---|
| Sector | Healthcare |
| Debt to Equity Ratio | 27.171 |
| Revenue per Share | 0.104 |
| Market Cap | 173,676,176 |
| Forward P/E | -1.28 |
| Beta | 2.28 |
| Website | https://cariboubio.com |
As of Aug. 22, 2026, 2:15 a.m. EDT: Speculators are positioning for a continued grind lower, evidenced by heavy put open interest at the $2.00 strike across multiple expirations, which acts as a significant resistance wall. While there is some call volume at $2.50, the overwhelming majority of open interest sits out-of-the-money on the downside side, suggesting a 'bear put spread' mentality rather than a bullish breakout attempt. Implied volatility remains elevated relative to deep ITM strikes, indicating fear of further downside moves.
| Attribute | Value |
|---|---|
| 52 Week Change | -0.13829786 |
| Address1 | 2,929 7th Street |
| Address2 | Suite 105 |
| All Time High | 32.645 |
| All Time Low | 0.66 |
| Ask | 1.63 |
| Ask Size | 1 |
| Average Daily Volume10 Day | 967,740 |
| Average Daily Volume3 Month | 1,758,993 |
| Average Volume | 1,758,993 |
| Average Volume10Days | 967,740 |
| Beta | 2.276 |
| Bid | 1.2 |
| Bid Size | 2 |
| Book Value | 0.926 |
| City | Berkeley |
| Compensation As Of Epoch Date | 1,767,139,200 |
| Country | United States |
| Crypto Tradeable | 0 |
| Currency | USD |
| Current Price | 1.62 |
| Current Ratio | 6.487 |
| Custom Price Alert Confidence | HIGH |
| Date Short Interest | 1,786,665,600 |
| Day High | 1.66 |
| Day Low | 1.6 |
| Debt To Equity | 27.171 |
| Display Name | Caribou Biosciences |
| Earnings Timestamp End | 1,794,427,200 |
| Earnings Timestamp Start | 1,794,427,200 |
| Ebitda | -104,609,000 |
| Ebitda Margins | 0.0 |
| Enterprise To Ebitda | -0.841 |
| Enterprise To Revenue | 8.771 |
| Enterprise Value | 88,017,168 |
| Eps Current Year | -1.175 |
| Eps Forward | -1.26333 |
| Eps Trailing Twelve Months | -1.05 |
| Esg Populated | 0 |
| Exchange | NMS |
| Exchange Data Delayed By | 0 |
| Exchange Timezone Name | America/New_York |
| Exchange Timezone Short Name | EDT |
| Fifty Day Average | 1.6667 |
| Fifty Day Average Change | -0.0467 |
| Fifty Day Average Change Percent | -0.02801944 |
| Fifty Two Week Change Percent | -13.829785 |
| Fifty Two Week High | 3.535 |
| Fifty Two Week High Change | -1.9150001 |
| Fifty Two Week High Change Percent | -0.54172564 |
| Fifty Two Week Low | 1.38 |
| Fifty Two Week Low Change | 0.24000001 |
| Fifty Two Week Low Change Percent | 0.17391305 |
| Fifty Two Week Range | 1.38 - 3.535 |
| Financial Currency | USD |
| First Trade Date Milliseconds | 1,627,047,000,000 |
| Float Shares | 102,908,492 |
| Forward Eps | -1.26333 |
| Forward P E | -1.2823253 |
| Free Cashflow | -59,605,500 |
| Full Exchange Name | NasdaqGS |
| Full Time Employees | 97 |
| Fullday Change | -0.04 |
| Fullday Change Percent | -2.40964 |
| Fullday Price | 1.65 |
| Gmt Off Set Milliseconds | -14,400,000 |
| Gross Margins | 0.0 |
| Gross Profits | -73,818,000 |
| Has Pre Post Market Data | 1 |
| Held Percent Insiders | 0.082440004 |
| Held Percent Institutions | 0.44852 |
| Implied Shares Outstanding | 107,207,513 |
| Industry | Biotechnology |
| Industry Disp | Biotechnology |
| Industry Key | biotechnology |
| Ipo Expected Date | 2,021-07-23 |
| Is Earnings Date Estimate | 1 |
| Language | en-US |
| Last Fiscal Year End | 1,767,139,200 |
| Long Business Summary | Caribou Biosciences, Inc. operates as a clinical-stage clustered regularly interspaced short palindromic repeats (CRISPR) genome-editing biopharmaceutical company. It offers a genome-editing platform based on novel CRISPR hybrid RNA-DNA genome-editing technology that enables precise genome editing of allogeneic cell therapies. The company develops Vispacabtagene Regedleucel, an allogeneic anti-CD19 CAR-T cell therapy that is in phase 1 clinical trial to treat relapsed or refractory B cell non-Hodgkin lymphoma; and CB-011, an allogeneic anti-BCMA CAR-T cell therapy that is in phase 1 clinical trial for the treatment of relapsed or refractory multiple myeloma. Caribou Biosciences, Inc. was incorporated in 2011 and is headquartered in Berkeley, California. |
| Long Name | Caribou Biosciences, Inc. |
| Market | us_market |
| Market Cap | 173,676,176 |
| Market State | CLOSED |
| Max Age | 86,400 |
| Message Board Id | finmb_272189231 |
| Most Recent Quarter | 1,782,777,600 |
| Net Income To Common | -103,403,000 |
| Next Fiscal Year End | 1,798,675,200 |
| Non Diluted Market Cap | 177,428,434 |
| Number Of Analyst Opinions | 7 |
| Open | 1.66 |
| Operating Cashflow | -95,780,000 |
| Operating Margins | -16.90394 |
| Payout Ratio | 0.0 |
| Phone | 510 982 6030 |
| Post Market Change | 0.029999971 |
| Post Market Change Percent | 1.85185 |
| Post Market Price | 1.65 |
| Post Market Time | 1,787,959,806 |
| Previous Close | 1.66 |
| Price Eps Current Year | -1.3787235 |
| Price Hint | 4 |
| Price To Book | 1.7494601 |
| Price To Sales Trailing12 Months | 17.307043 |
| Profit Margins | 0.0 |
| Quick Ratio | 6.357 |
| Quote Source Name | Nasdaq Real Time Price |
| Quote Type | EQUITY |
| Recommendation Key | none |
| Region | US |
| Regular Market Change | -0.04 |
| Regular Market Change Percent | -2.40964 |
| Regular Market Day High | 1.66 |
| Regular Market Day Low | 1.6 |
| Regular Market Day Range | 1.6 - 1.66 |
| Regular Market Open | 1.66 |
| Regular Market Previous Close | 1.66 |
| Regular Market Price | 1.62 |
| Regular Market Time | 1,787,947,201 |
| Regular Market Volume | 666,306 |
| Return On Assets | -0.36845002 |
| Return On Equity | -0.78266 |
| Revenue Growth | -0.438 |
| Revenue Per Share | 0.104 |
| Sand P52 Week Change | 0.20204377 |
| Sector | Healthcare |
| Sector Disp | Healthcare |
| Sector Key | healthcare |
| Shares Outstanding | 107,207,513 |
| Shares Percent Shares Out | 0.1163 |
| Shares Short | 12,465,346 |
| Shares Short Previous Month Date | 1,784,073,600 |
| Shares Short Prior Month | 11,594,287 |
| Short Name | Caribou Biosciences, Inc. |
| Short Percent Of Float | 0.120699994 |
| Short Ratio | 9.79 |
| Source Interval | 15 |
| State | CA |
| Symbol | CRBU |
| Target High Price | 32.0 |
| Target Low Price | 4.0 |
| Target Mean Price | 11.85714 |
| Target Median Price | 10.0 |
| Total Cash | 112,314,000 |
| Total Cash Per Share | 1.048 |
| Total Debt | 26,655,000 |
| Total Revenue | 10,035,000 |
| Tradeable | 0 |
| Trailing Annual Dividend Rate | 0.0 |
| Trailing Annual Dividend Yield | 0.0 |
| Trailing Eps | -1.05 |
| Trailing Peg Ratio | None |
| Triggerable | 1 |
| Two Hundred Day Average | 1.80405 |
| Two Hundred Day Average Change | -0.18404996 |
| Two Hundred Day Average Change Percent | -0.102020435 |
| Type Disp | Equity |
| Volume | 666,306 |
| Website | https://cariboubio.com |
| Zip | 94,710 |