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Coya Therapeutics, Inc. (COYA)

Healthcare | Biotechnology | Houston, United States | NasdaqCM
4.59 USD -0.27 (-5.556%) ⇩ (Aug. 28, 2026, 4 p.m. EDT)
After hours: 4.57 -0.02 (-0.019%) ⇩ (Aug. 28, 2026, 7:30 p.m. EDT)

Short-term:★★☆☆☆Long-term:★★☆☆☆Dividends:☆☆☆☆☆
Hot Take | Aug. 22, 2026, 2:32 a.m. EDT

The investment case for Coya Therapeutics is currently bifurcated between a compelling long-term narrative and a precarious short-term reality. Fundamentally, the company is showing signs of life with a 49% revenue growth rate and a price trajectory that has surged nearly 95% over the last two years, driven by positive year-over-year performance. However, these gains are built on a foundation of significant losses, with negative operating margins of nearly 29% and no free cash flow. The balance sheet remains fragile, relying on capital raises like the recent $11.1 million private placement to fund operations, while the gross margin is negative, indicating severe cost inefficiencies in production or sales. While analysts maintain a 'strong buy' rating with a mean target of $15, this optimism appears disconnected from the current operational burn rate and the lack of commercialized revenue. The stock is trading at a premium valuation relative to its sales, which is typical for biotech but risky without a proven product pipeline. In the short term, the technical picture is mixed; the stock is hovering near its 50-day average but lacks the explosive momentum needed to justify a bullish entry given the low reliability of statistical forecasts. The options market reflects this uncertainty, with heavy put buying at the $2.50 level acting as a psychological floor, while call interest at $7.50 represents a distant dream scenario. Until the company demonstrates a path to profitability or a major clinical milestone that de-risks the pipeline, the risk-reward profile remains skewed toward caution.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoARIMA ✓0.074136
AutoTheta0.098964
AutoETS0.107884
MSTL0.117786

Forecast horizon: 45 days | Selected: AutoARIMA

Forecast Reliability
Score 48%
H-stat 0.07
Ljung-Box p 0.000
Jarque-Bera p 0.895
Excess Kurtosis -0.26
Attribute Value
Sector Healthcare
Revenue per Share 0.403
Market Cap 107,671,528
Forward P/E -2.44
Profit Margins -270.22%
Website https://www.coyatherapeutics.com

As of Aug. 22, 2026, 2:32 a.m. EDT: Speculators are positioning for a range-bound outcome rather than a directional breakout. Call open interest is heavily concentrated at the $7.50 strike, suggesting a speculative ceiling or a 'lottery ticket' bet on a massive rally, while the bulk of volume sits at-the-money. Conversely, put open interest is significantly heavier at the $2.50 strike, indicating a defined floor where investors believe the stock could fall. The implied volatility gap between the near-term ATM ($26%) and deep OTM/ITM strikes suggests traders expect a potential spike in price movement but are hedging against a drop to the lower end of the range.


Info Dump

Attribute Value
52 Week Change -0.29601228
Address1 5,850 San Felipe St.
Address2 Suite 500
All Time High 10.69
All Time Low 3.21
Ask 5.9
Ask Size 2
Average Analyst Rating 1.0 - Strong Buy
Average Daily Volume10 Day 100,030
Average Daily Volume3 Month 194,287
Average Volume 194,287
Average Volume10Days 100,030
Bid 3.48
Bid Size 2
Book Value 1.845
City Houston
Compensation As Of Epoch Date 1,767,139,200
Country United States
Crypto Tradeable 0
Currency USD
Current Price 4.59
Current Ratio 13.397
Custom Price Alert Confidence HIGH
Date Short Interest 1,786,665,600
Day High 4.82
Day Low 4.55
Display Name Coya Therapeutics
Earnings Timestamp 1,786,451,400
Earnings Timestamp End 1,794,400,200
Earnings Timestamp Start 1,794,400,200
Ebitda -20,830,436
Ebitda Margins -2.59759
Enterprise To Ebitda -3.096
Enterprise To Revenue 8.042
Enterprise Value 64,490,524
Eps Current Year -1.36667
Eps Forward -1.88
Eps Trailing Twelve Months -1.01
Esg Populated 0
Exchange NCM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 4.8724
Fifty Day Average Change -0.28239965
Fifty Day Average Change Percent -0.057959046
Fifty Two Week Change Percent -29.601229
Fifty Two Week High 7.75
Fifty Two Week High Change -3.1599998
Fifty Two Week High Change Percent -0.4077419
Fifty Two Week Low 3.71
Fifty Two Week Low Change 0.8800001
Fifty Two Week Low Change Percent 0.23719679
Fifty Two Week Range 3.71 - 7.75
Financial Currency USD
First Trade Date Milliseconds 1,672,324,200,000
Float Shares 17,285,620
Forward Eps -1.88
Forward P E -2.4414895
Free Cashflow -11,967,820
Full Exchange Name NasdaqCM
Full Time Employees 8
Fullday Change -0.27
Fullday Change Percent -5.55555
Fullday Price 4.5712
Gmt Off Set Milliseconds -14,400,000
Gross Margins -1.08682
Gross Profits -8,715,404
Has Pre Post Market Data 1
Held Percent Insiders 0.1469
Held Percent Institutions 0.33234
Implied Shares Outstanding 23,457,849
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Ipo Expected Date 2,022-12-29
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Coya Therapeutics, Inc., a clinical-stage biotechnology company, engages in the development of proprietary therapies to enhance the function of regulatory T cells (Tregs). Its candidate product pipeline is based on therapeutic modalities, such as Treg-enhancing biologics, Treg-derived exosomes, and autologous Treg cell therapy. The company develops COYA 302, a biologic combination for subcutaneous administration intended to enhance Treg function while depleting T effector function and activated macrophages in Phase 2 trial for use in the treatment of amyotrophic lateral sclerosis, as well as frontotemporal dementia, Alzheimer's disease (AD), and Parkinson's disease. In addition, its pre-clinical product candidates include COYA 301, a low-dose interleukin 2 product candidate to treat AD; COYA 303, an investigational biologic combination of COYA 301 and a glucagon-like-peptide-1 receptor agonist for the treatment of inflammatory diseases; COYA 201, an antigen directed Treg-derived exosome product candidate to treat neurodegenerative, autoimmune, and metabolic diseases; COYA 206, an antigen directed Treg-derived exosome product candidate; and COYA 101. It has a collaboration with Dr. Reddy's Laboratories SA for the development and commercialization of COYA 302, an investigational combination therapy for treatment of amyotrophic lateral sclerosis. Coya Therapeutics, Inc. was founded in 2020 and is headquartered in Houston, Texas.
Long Name Coya Therapeutics, Inc.
Market us_market
Market Cap 107,671,528
Market State CLOSED
Max Age 86,400
Message Board Id finmb_700238507
Most Recent Quarter 1,782,777,600
Net Income To Common -21,669,624
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 113,770,567
Number Of Analyst Opinions 7
Open 4.82
Operating Cashflow -15,722,176
Operating Margins -28.904518
Payout Ratio 0.0
Phone 800 587 8170
Post Market Change -0.018800259
Post Market Change Percent -0.40959167
Post Market Price 4.5712
Post Market Time 1,787,959,805
Previous Close 4.86
Price Eps Current Year -3.3585284
Price Hint 4
Price To Book 2.487805
Price To Sales Trailing12 Months 13.426809
Profit Margins -2.70224
Quick Ratio 12.294
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.0
Region US
Regular Market Change -0.27
Regular Market Change Percent -5.55555
Regular Market Day High 4.82
Regular Market Day Low 4.55
Regular Market Day Range 4.55 - 4.82
Regular Market Open 4.82
Regular Market Previous Close 4.86
Regular Market Price 4.59
Regular Market Time 1,787,947,201
Regular Market Volume 152,927
Return On Assets -0.32271
Return On Equity -0.60541
Revenue Growth 0.49
Revenue Per Share 0.403
Sand P52 Week Change 0.20204377
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 23,457,849
Shares Percent Shares Out 0.045100003
Shares Short 1,057,492
Shares Short Previous Month Date 1,784,073,600
Shares Short Prior Month 1,048,435
Short Name Coya Therapeutics, Inc.
Short Percent Of Float 0.045500003
Short Ratio 5.55
Source Interval 15
State TX
Symbol COYA
Target High Price 18.0
Target Low Price 12.0
Target Mean Price 15.21429
Target Median Price 15.5
Total Cash 43,181,000
Total Cash Per Share 1.841
Total Debt 0
Total Revenue 8,019,145
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -1.01
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 4.895475
Two Hundred Day Average Change -0.30547476
Two Hundred Day Average Change Percent -0.062399413
Type Disp Equity
Volume 152,927
Website https://www.coyatherapeutics.com
Zip 77,057