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Cogent Biosciences, Inc. (COGT)

Healthcare | Biotechnology | Waltham, United States | NasdaqGS
37.25 USD +1.06 (2.929%) ⇧ (April 17, 2026, 4 p.m. EDT)
After hours: 37.51 +0.26 (0.698%) ⇧ (April 17, 2026, 6:27 p.m. EDT)

Short-term: ★★★★☆ | Long-term: ★★★★☆ | Dividends: ☆☆☆☆☆
Hot Take | April 18, 2026, 10:31 p.m. EDT

Cogent is a 'strong buy' on a proxy basis, driven by elite validation from Stan Druckenmiller and imminent catalyst (Bezuclastinib launch) rather than current P&L. The stock trades at a $37 price level against a $54 consensus target, with a massive amount of OTM call leakage at $40+, signaling the market is pricing in a massive move to the upside upon the launch. The risk is regulatory delay or post-launch execution failure, which is why the 5-year forward PE is negative—this is a venture capital bill, not a value investment, making it a high-conviction momentum long.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoETS ✓0.046762
MSTL0.048473
AutoARIMA0.048703
AutoTheta0.059061

Forecast horizon: 45 days | Selected: AutoETS

Forecast Reliability
Score 49%
H-stat 4.34
Ljung-Box p 0.000
Jarque-Bera p 0.648
Excess Kurtosis -0.58
Attribute Value
Sector Healthcare
Debt to Equity Ratio 37.525
Market Cap 6,046,003,200
Forward P/E -54.08
Beta 0.47
Website https://www.cogentbio.com

As of April 18, 2026, 10:31 p.m. EDT: Options flow is heavily skewed towards long calls with significant ICE buildup (Open Interest) at OTM strikes of $40.00 and $50.00 for late 2026 and beyond, suggesting strong bullish positioning and a 'wait-for-the-upside' mentality. While ATM calls at $35-$37 show moderate activity, the concentration of long-dated OTM call OI far outweighs the put positioning. Interestingly, puts show high velocity at the $28-$34 strikes in the near term (April-May), indicating some hedging or downside stops, but the dominant flow is speculative bullishness betting on the upcoming bezuclastinib launch. Implied volatility is notably elevated on extreme strikes, reflecting a belief in a binary probabilistic event (Catalyst/FDA approval) rather than steady drift.


Info Dump

Attribute Value
52 Week Change 7.6627903
Address1 275 Wyman Street
Address2 3rd Floor
All Time High 70.64
All Time Low 1.18
Ask 47.5
Ask Size 2
Audit Risk 5
Average Analyst Rating 1.5 - Strong Buy
Average Daily Volume10 Day 2,168,860
Average Daily Volume3 Month 2,149,150
Average Volume 2,149,150
Average Volume10Days 2,168,860
Beta 0.474
Bid 26.7
Bid Size 2
Board Risk 6
Book Value 3.396
City Waltham
Compensation As Of Epoch Date 1,735,603,200
Compensation Risk 8
Country United States
Crypto Tradeable 0
Currency USD
Current Price 37.25
Current Ratio 14.235
Custom Price Alert Confidence HIGH
Date Short Interest 1,774,915,200
Day High 37.3
Day Low 36.59
Debt To Equity 37.525
Display Name Cogent Biosciences
Dividend Date 1,604,880,000
Earnings Timestamp 1,771,335,000
Earnings Timestamp End 1,777,984,200
Earnings Timestamp Start 1,777,984,200
Ebitda -330,799,008
Ebitda Margins 0.0
Enterprise To Ebitda -16.405
Enterprise Value 5,426,610,176
Eps Current Year -2.14939
Eps Forward -0.68876
Eps Trailing Twelve Months -2.16
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 36.6804
Fifty Day Average Change 0.56959915
Fifty Day Average Change Percent 0.015528706
Fifty Two Week Change Percent 766.27905
Fifty Two Week High 43.73
Fifty Two Week High Change -6.4799995
Fifty Two Week High Change Percent -0.14818202
Fifty Two Week Low 4.2
Fifty Two Week Low Change 33.05
Fifty Two Week Low Change Percent 7.8690476
Fifty Two Week Range 4.2 - 43.73
Financial Currency USD
First Trade Date Milliseconds 1,522,330,200,000
Float Shares 150,971,712
Forward Eps -0.68876
Forward P E -54.0827
Free Cashflow -152,490,624
Full Exchange Name NasdaqGS
Full Time Employees 258
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,775,001,600
Gross Margins 0.0
Has Pre Post Market Data 1
Held Percent Insiders 0.0030399999
Held Percent Institutions 1.07743
Implied Shares Outstanding 162,308,820
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Last Split Date 1,604,880,000
Last Split Factor 1:4
Long Business Summary Cogent Biosciences, Inc., a clinical-stage biotechnology company, focuses on developing precision therapies for genetically defined diseases. Its lead product candidate includes bezuclastinib (CGT9486), a selective tyrosine kinase inhibitor in Phase 3 trial designed to target mutations within the KIT receptor tyrosine kinase, including KIT D816V mutation that drives systemic mastocytosis, as well as other mutations in KIT exon 17, which are found in patients with advanced gastrointestinal stromal tumors. The company also develops CGT4859, a reversible and selective fibroblast growth factor receptor 2 inhibitor in Phase 1 trial for patients with documented FGFR mutations, including advanced cholangiocarcinoma; CGT4255, a novel ErbB2 mutant program, which is focused on actionable and underserved mutations in a solid tumor systemic and CNS involved indications; and CGT6297, a Novel PI3Ka mutant-selective inhibitor. It has a licensing agreement with Plexxikon Inc. for the research, development, and commercialization of bezuclastinib. Cogent Biosciences, Inc. is headquartered in Waltham, Massachusetts.
Long Name Cogent Biosciences, Inc.
Market us_market
Market Cap 6,046,003,200
Market State CLOSED
Max Age 86,400
Message Board Id finmb_675599465
Most Recent Quarter 1,767,139,200
Net Income To Common -328,936,992
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 6,044,380,456
Number Of Analyst Opinions 12
Open 36.98
Operating Cashflow -264,444,000
Operating Margins 0.0
Overall Risk 7
Payout Ratio 0.0
Phone 617-945-5576
Post Market Change 0.25999832
Post Market Change Percent 0.6979821
Post Market Price 37.51
Post Market Time 1,776,464,859
Previous Close 36.19
Price Eps Current Year -17.330498
Price Hint 2
Price To Book 10.968787
Profit Margins 0.0
Quick Ratio 14.085
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.46154
Region US
Regular Market Change 1.06
Regular Market Change Percent 2.92899
Regular Market Day High 37.3
Regular Market Day Low 36.59
Regular Market Day Range 36.59 - 37.3
Regular Market Open 36.98
Regular Market Previous Close 36.19
Regular Market Price 37.25
Regular Market Time 1,776,456,001
Regular Market Volume 3,869,493
Return On Assets -0.32928002
Return On Equity -0.73697996
Sand P52 Week Change 0.38150132
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 9
Shares Outstanding 162,308,820
Shares Percent Shares Out 0.1074
Shares Short 17,425,998
Shares Short Previous Month Date 1,772,150,400
Shares Short Prior Month 16,112,481
Short Name Cogent Biosciences, Inc.
Short Percent Of Float 0.1196
Short Ratio 7.99
Source Interval 15
State MA
Symbol COGT
Target High Price 72.0
Target Low Price 35.0
Target Mean Price 54.16667
Target Median Price 55.0
Total Cash 900,764,992
Total Cash Per Share 5.593
Total Debt 238,796,992
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -2.16
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 26.187725
Two Hundred Day Average Change 11.062275
Two Hundred Day Average Change Percent 0.42242214
Type Disp Equity
Volume 3,869,493
Website https://www.cogentbio.com
Zip 2,451