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Cogent Biosciences, Inc. (COGT)

Healthcare | Biotechnology | Waltham, United States | NasdaqGS
34.67 USD -2.42 (-6.525%) ⇩ (Aug. 28, 2026, 4 p.m. EDT)
After hours: 34.59 -0.08 (-0.084%) ⇩ (Aug. 28, 2026, 7:30 p.m. EDT)

Short-term:★★⯪☆☆Long-term:★★⯪☆☆Dividends:☆☆☆☆☆
Hot Take | Aug. 22, 2026, 4:15 a.m. EDT

Cogent Biosciences presents a classic biotech dilemma: exceptional balance sheet strength masking severe fundamental deterioration. The company holds a fortress-like liquidity position with a massive cash reserve relative to debt and a negligible short float, suggesting management is well-capitalized to pursue its pipeline. However, the business itself is currently failing to generate value, evidenced by deep losses in both assets and equity, negative free cash flow, and a trailing P/E that is mathematically undefined due to negative earnings. The stock has suffered a catastrophic multi-year decline, dropping nearly 80% over the last seven years, which serves as a stark warning that the market does not believe the current pipeline can yet deliver commercial success. Despite a 'strong buy' analyst recommendation driven by potential future upside, the lack of a dividend and the absence of recent positive annual returns suggest the investment thesis remains unproven. Options activity confirms this skepticism, with traders aggressively buying downside protection while waiting for a binary event to drive the price higher.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
MSTL ✓0.095916
AutoETS0.096599
AutoARIMA0.097018
AutoTheta0.121465

Forecast horizon: 45 days | Selected: MSTL

Forecast Reliability
Score 44%
H-stat 2.97
Ljung-Box p 0.000
Jarque-Bera p 0.105
Excess Kurtosis -1.00
Attribute Value
Sector Healthcare
Debt to Equity Ratio 45.88
Market Cap 6,016,110,592
Forward P/E -31.28
Beta 0.33
Previous Name Unum Therapeutics Inc.
Website https://www.cogentbio.com

As of Aug. 22, 2026, 4:15 a.m. EDT: Speculators are positioning defensively with heavy put volume relative to calls, particularly in the near term where out-of-the-money puts show significant open interest. While there is some call volume at strikes significantly above the current price (indicating a speculative hope for a catalyst-driven rally), the dominant flow is hedging or betting against a continued decline, with implied volatility remaining elevated on downside protection.


Info Dump

Attribute Value
52 Week Change 2.0703642
Address1 275 Wyman Street
Address2 3rd Floor
All Time High 70.64
All Time Low 1.18
Ask 44.2
Ask Size 5
Audit Risk 6
Average Analyst Rating 1.3 - Strong Buy
Average Daily Volume10 Day 1,499,190
Average Daily Volume3 Month 2,411,269
Average Volume 2,419,800
Average Volume10Days 1,499,190
Beta 0.329
Bid 33.5
Bid Size 3
Board Risk 6
Book Value 2.724
City Waltham
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 9
Country United States
Crypto Tradeable 0
Currency USD
Current Price 34.67
Current Ratio 13.573
Custom Price Alert Confidence HIGH
Date Short Interest 1,786,665,600
Day High 36.845
Day Low 34.53
Debt To Equity 45.88
Display Name Cogent Biosciences
Dividend Date 1,604,880,000
Earnings Timestamp 1,786,365,000
Earnings Timestamp End 1,793,709,000
Earnings Timestamp Start 1,793,709,000
Ebitda -386,456,992
Ebitda Margins 0.0
Enterprise To Ebitda -14.321
Enterprise Value 5,534,348,288
Eps Current Year -2.2143
Eps Forward -1.10821
Eps Trailing Twelve Months -2.16
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 38.6352
Fifty Day Average Change -3.9652023
Fifty Day Average Change Percent -0.10263186
Fifty Two Week Change Percent 209.08334
Fifty Two Week High 43.73
Fifty Two Week High Change -9.060001
Fifty Two Week High Change Percent -0.20718046
Fifty Two Week Low 11.6
Fifty Two Week Low Change 23.069998
Fifty Two Week Low Change Percent 1.9887929
Fifty Two Week Range 11.6 - 43.73
Financial Currency USD
First Trade Date Milliseconds 1,522,330,200,000
Float Shares 172,560,477
Forward Eps -1.10821
Forward P E -31.284683
Free Cashflow -186,149,376
Full Exchange Name NasdaqGS
Full Time Employees 258
Fullday Change -2.42
Fullday Change Percent -6.52468
Fullday Price 34.5861
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,785,542,400
Gross Margins 0.0
Has Pre Post Market Data 1
Held Percent Insiders 0.00424
Held Percent Institutions 1.1497799
Implied Shares Outstanding 173,524,982
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Last Split Date 1,604,880,000
Last Split Factor 1:4
Long Business Summary Cogent Biosciences, Inc., a clinical-stage biotechnology company, focuses on developing precision therapies for genetically defined diseases. Its lead product candidate includes bezuclastinib (CGT9486), a selective tyrosine kinase inhibitor in Phase 3 trial designed to target mutations within the KIT receptor tyrosine kinase, including KIT D816V mutation that drives systemic mastocytosis, as well as other mutations in KIT exon 17, which are found in patients with advanced gastrointestinal stromal tumors. The company also develops CGT4859, a reversible and selective fibroblast growth factor receptor 2 inhibitor in Phase 1 trial for patients with documented FGFR mutations, including advanced cholangiocarcinoma; CGT4255, a novel ErbB2 mutant program, which is focused on actionable and underserved mutations in a solid tumor systemic and CNS involved indications; and CGT6297, a Novel PI3Ka mutant-selective inhibitor. It has a licensing agreement with Plexxikon Inc. for the research, development, and commercialization of bezuclastinib. Cogent Biosciences, Inc. is headquartered in Waltham, Massachusetts.
Long Name Cogent Biosciences, Inc.
Market us_market
Market Cap 6,016,110,592
Market State CLOSED
Max Age 86,400
Message Board Id finmb_675599465
Most Recent Quarter 1,782,777,600
Name Change Date 2,026-08-28
Net Income To Common -377,179,008
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 6,434,306,332
Number Of Analyst Opinions 11
Open 36.66
Operating Cashflow -307,544,992
Operating Margins 0.0
Overall Risk 8
Payout Ratio 0.0
Phone 617 945 5576
Post Market Change -0.08389664
Post Market Change Percent -0.24198627
Post Market Price 34.5861
Post Market Time 1,787,959,805
Prev Name Unum Therapeutics Inc.
Previous Close 37.09
Price Eps Current Year -15.657318
Price Hint 2
Price To Book 12.727606
Profit Margins 0.0
Quick Ratio 13.362
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.33333
Region US
Regular Market Change -2.42
Regular Market Change Percent -6.52468
Regular Market Day High 36.845
Regular Market Day Low 34.53
Regular Market Day Range 34.53 - 36.845
Regular Market Open 36.66
Regular Market Previous Close 37.09
Regular Market Price 34.67
Regular Market Time 1,787,947,201
Regular Market Volume 1,771,022
Return On Assets -0.43842
Return On Equity -1.09737
Sand P52 Week Change 0.1966995
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 8
Shares Outstanding 173,524,982
Shares Percent Shares Out 0.10609999
Shares Short 18,411,111
Shares Short Previous Month Date 1,784,073,600
Shares Short Prior Month 16,557,226
Short Name Cogent Biosciences, Inc.
Short Percent Of Float 0.1067
Short Ratio 9.61
Source Interval 15
State MA
Symbol COGT
Target High Price 62.0
Target Low Price 45.0
Target Mean Price 55.81818
Target Median Price 55.0
Total Cash 792,300,032
Total Cash Per Share 4.565
Total Debt 244,260,992
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -2.16
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 36.92465
Two Hundred Day Average Change -2.25465
Two Hundred Day Average Change Percent -0.061060842
Type Disp Equity
Volume 1,771,022
Website https://www.cogentbio.com
Zip 2,451