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Compass Therapeutics, Inc. (CMPX)

Healthcare | Biotechnology | Boston, United States | NasdaqCM
0.88 USD -0.02 (-2.108%) ⇩ (Oct. 16, 2026, 3:36 p.m. EDT)

Short-term:★☆☆☆☆Long-term:★★⯪☆☆Dividends:☆☆☆☆☆
Hot Take ↕ | Oct. 10, 2026, 1:12 a.m. EDT

The investment case for Compass Therapeutics is currently defined by severe distress rather than opportunity. Fundamentally, the company is bleeding cash with negative free cash flow and negative returns on equity, while trading at a fraction of its book value. The price action confirms this deterioration, with the stock tumbling from a high of $6.88 to trade near $1.00, erasing nearly 85% of its value over the last year. While the long-term trajectory shows a recent recovery in annual returns, the underlying business remains unprofitable with no dividend support. The short-term outlook is bearish due to overwhelming options positioning. The market is pricing in a continued decline, with traders aggressively buying deep out-of-the-money puts for 2027 expiration while offering almost no call liquidity. This asymmetry suggests that even optimistic news, such as upcoming clinical data presentations, may be insufficient to reverse the trend without significant catalysts. The statistical forecasting models are unreliable, adding no clarity to the noise. Until the company demonstrates a path to profitability or a definitive regulatory approval that changes the risk profile, the balance sheet risks and lack of income make this a poor vehicle for capital preservation.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
MSTL ✓0.153337
AutoETS0.153706
AutoARIMA0.153767
AutoTheta0.155022

Forecast horizon: 45 days | Selected: MSTL

Forecast Reliability
Score 20%
H-stat 22.68
Ljung-Box p 0.000
Jarque-Bera p 0.000
Excess Kurtosis 1.83
Attribute Value
Sector Healthcare
Debt to Equity Ratio 5.801
Market Cap 158,081,168
Forward P/E -1.63
Beta 0.91
Website https://www.compasstherapeutics.com

As of Oct. 10, 2026, 1:12 a.m. EDT: Speculators are overwhelmingly positioning for downside protection, evidenced by massive open interest in out-of-the-money puts expiring in late 2027 (over 41,000 contracts at the $1 strike). Conversely, call activity is negligible, with virtually no volume or open interest beyond the immediate term, indicating a lack of speculative bullish conviction despite the low implied volatility environment.


Info Dump

Attribute Value
52 Week Change -0.78943664
Address1 80 Guest Street
Address2 Suite 601
All Time High 11.0
All Time Low 0.765
Ask 1.12
Ask Size 2
Audit Risk 6
Average Daily Volume10 Day 7,390,770
Average Daily Volume3 Month 4,299,754
Average Volume 4,299,754
Average Volume10Days 7,390,770
Beta 0.914
Bid 0.6278
Bid Size 2
Board Risk 7
Book Value 0.922
City Boston
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 8
Country United States
Crypto Tradeable 0
Currency USD
Current Price 0.8778
Current Ratio 11.216
Custom Price Alert Confidence HIGH
Date Short Interest 1,790,726,400
Day High 0.9092
Day Low 0.8601
Debt To Equity 5.801
Display Name Compass Therapeutics
Dividend Yield 0.0
Earnings Call Timestamp End 1,754,913,600
Earnings Call Timestamp Start 1,754,913,600
Earnings Timestamp 1,786,019,400
Earnings Timestamp End 1,793,881,800
Earnings Timestamp Start 1,793,881,800
Ebitda -81,013,000
Ebitda Margins 0.0
Enterprise To Ebitda 0.108
Enterprise Value -8,761,167
Eps Current Year -0.48455
Eps Forward -0.538
Eps Trailing Twelve Months -0.39
Esg Populated 0
Exchange NCM
Exchange Data Delayed By 15
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 1.78798
Fifty Day Average Change -0.91018
Fifty Day Average Change Percent -0.5090549
Fifty Two Week Change Percent -78.943665
Fifty Two Week High 6.88
Fifty Two Week High Change -6.0022
Fifty Two Week High Change Percent -0.8724128
Fifty Two Week Low 0.822
Fifty Two Week Low Change 0.05579996
Fifty Two Week Low Change Percent 0.06788316
Fifty Two Week Range 0.822 - 6.88
Financial Currency USD
First Trade Date Milliseconds 1,617,629,400,000
Float Shares 132,424,047
Forward Eps -0.538
Forward P E -1.6315985
Free Cashflow -31,361,124
Full Exchange Name NasdaqCM
Full Time Employees 39
Fullday Change -0.018900037
Fullday Change Percent -2.1077323
Fullday Price 0.8778
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,790,812,800
Gross Margins 0.0
Has Pre Post Market Data 1
Held Percent Insiders 0.12467
Held Percent Institutions 0.88558996
Implied Shares Outstanding 180,087,915
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Ipo Expected Date 2,021-11-02
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Compass Therapeutics, Inc., a clinical-stage oncology-focused biopharmaceutical company, develops antibody-based therapeutics for the treatment of various human diseases in the United States. The company's lead product candidate, tovecimig, is a bispecific antibody that targets delta-like ligand 4 (DLL4) and vascular endothelial growth factor A (VEGF-A), which are critical to angiogenesis and tumor vascularization. It also develops CTX-471, an IgG4 monoclonal antibody that is an agonist of CD137, a key co-stimulatory receptor on immune cells; CTX-8371, a bispecific inhibitor that targets programmed cell death protein-1 (PD-1) and ligand PD-L1 checkpoint inhibitor antibodies; and CTX-10726, a bispecific antibody that targets PD-1 and VEFG-A. The company was founded in 2014 and is headquartered in Boston, Massachusetts.
Long Name Compass Therapeutics, Inc.
Market us_market
Market Cap 158,081,168
Market State REGULAR
Max Age 86,400
Message Board Id finmb_266166780
Most Recent Quarter 1,782,777,600
Net Income To Common -73,446,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 210,702,860
Number Of Analyst Opinions 11
Open 0.9
Operating Cashflow -56,110,000
Operating Margins 0.0
Overall Risk 7
Phone 617 500 8099
Previous Close 0.8967
Price Eps Current Year -1.8115777
Price Hint 4
Price To Book 0.95206076
Profit Margins 0.0
Quick Ratio 11.153
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key none
Region US
Regular Market Change -0.018900037
Regular Market Change Percent -2.1077323
Regular Market Day High 0.9092
Regular Market Day Low 0.8601
Regular Market Day Range 0.8601 - 0.9092
Regular Market Open 0.9
Regular Market Previous Close 0.8967
Regular Market Price 0.8778
Regular Market Time 1,792,179,372
Regular Market Volume 1,159,324
Return On Assets -0.33029
Return On Equity -0.56659
Sand P52 Week Change 0.16207206
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 8
Shares Outstanding 180,087,915
Shares Percent Shares Out 0.2241
Shares Short 40,357,710
Shares Short Previous Month Date 1,788,134,400
Shares Short Prior Month 40,788,891
Short Name Compass Therapeutics, Inc.
Short Percent Of Float 0.26790002
Short Ratio 8.74
Source Interval 15
State MA
Symbol CMPX
Target High Price 12.0
Target Low Price 1.0
Target Mean Price 5.45455
Target Median Price 6.0
Total Cash 179,879,008
Total Cash Per Share 0.999
Total Debt 9,633,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -0.39
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 3.440345
Two Hundred Day Average Change -2.562545
Two Hundred Day Average Change Percent -0.7448512
Type Disp Equity
Volume 1,159,324
Website https://www.compasstherapeutics.com
Zip 2,135