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Compass Therapeutics, Inc. (CMPX)

Healthcare | Biotechnology | Boston, United States | NasdaqCM
6.00 USD -0.53 (-8.116%) ⇩ (April 17, 2026, 4 p.m. EDT)
After hours: 6.00 +0.00 (0.003%) ⇧ (April 17, 2026, 7:47 p.m. EDT)

Short-term: ★★★★☆ | Long-term: ★☆☆☆☆ | Dividends: ☆☆☆☆☆
Hot Take | April 18, 2026, 10:44 p.m. EDT

Despite the negative fundamentals and high-beta risk of a pre-revenue biotech with negative earnings, the market is rallying on specific clinical trial milestones (CTX-10726). The options chain acts as a clear contrarian signal to the short-seller crowd; with massive call volume at the 8.0 strike and analysts averaging $13.64, a short-term breakout above the 50-day average is the most probable near-term play, assuming the earnings estimate next month does not derail the momentum.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
MSTL ✓0.109784
AutoARIMA0.111249
AutoETS0.111309
AutoTheta0.139324

Forecast horizon: 45 days | Selected: MSTL

Forecast Reliability
Score 42%
H-stat 23.10
Ljung-Box p 0.000
Jarque-Bera p 0.147
Excess Kurtosis -1.23
Attribute Value
Sector Healthcare
Debt to Equity Ratio 4.995
Market Cap 1,080,527,488
Forward P/E -12.44
Beta 1.30
Website https://www.compasstherapeutics.com

As of April 18, 2026, 10:44 p.m. EDT: Options flow reveals a strong bullish bias. Call volume significantly outpaces put volume in near-term expirations (April, May). Specifically, massive call volume (27k) accumulated at the 8.0 SR, which represents a +33.3% upside from the current ~6.0 price. Despite high implied volatility for upside strikes (Bull Put Spread/Leverage), the speculation is heavily skewed towards calls. Put activity is concentrated in lower strikes (3.0, 4.0, 5.0) suggesting a floor defense below 5.0, whereas the majority of aggressive positioning targets the 6.0-8.0 range.


Info Dump

Attribute Value
52 Week Change 2.3707864
Address1 80 Guest Street
Address2 Suite 601
All Time High 11.0
All Time Low 0.765
Ask 7.55
Ask Size 2
Audit Risk 8
Average Analyst Rating 1.2 - Strong Buy
Average Daily Volume10 Day 3,366,060
Average Daily Volume3 Month 2,324,469
Average Volume 2,324,469
Average Volume10Days 3,366,060
Beta 1.3
Bid 4.73
Bid Size 2
Board Risk 7
Book Value 1.104
City Boston
Compensation As Of Epoch Date 1,735,603,200
Compensation Risk 9
Country United States
Crypto Tradeable 0
Currency USD
Current Price 6.0
Current Ratio 15.021
Custom Price Alert Confidence HIGH
Date Short Interest 1,774,915,200
Day High 6.67
Day Low 5.87
Debt To Equity 4.995
Display Name Compass Therapeutics
Earnings Call Timestamp End 1,754,913,600
Earnings Call Timestamp Start 1,754,913,600
Earnings Timestamp 1,772,717,400
Earnings Timestamp End 1,778,761,800
Earnings Timestamp Start 1,778,761,800
Ebitda -72,563,000
Ebitda Margins 0.0
Enterprise To Ebitda -12.147
Enterprise Value 881,450,496
Eps Current Year -0.41077
Eps Forward -0.4825
Eps Trailing Twelve Months -0.42
Esg Populated 0
Exchange NCM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 5.697
Fifty Day Average Change 0.30299997
Fifty Day Average Change Percent 0.053185884
Fifty Two Week Change Percent 237.07864
Fifty Two Week High 6.88
Fifty Two Week High Change -0.8800001
Fifty Two Week High Change Percent -0.127907
Fifty Two Week Low 1.665
Fifty Two Week Low Change 4.335
Fifty Two Week Low Change Percent 2.6036036
Fifty Two Week Range 1.665 - 6.88
Financial Currency USD
First Trade Date Milliseconds 1,617,629,400,000
Float Shares 118,868,829
Forward Eps -0.4825
Forward P E -12.435233
Free Cashflow -26,161,376
Full Exchange Name NasdaqCM
Full Time Employees 39
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,775,001,600
Gross Margins 0.0
Has Pre Post Market Data 1
Held Percent Insiders 0.111420006
Held Percent Institutions 0.87654
Implied Shares Outstanding 180,087,915
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Ipo Expected Date 2,021-11-02
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Compass Therapeutics, Inc., a clinical-stage oncology-focused biopharmaceutical company, develops antibody-based therapeutics for the treatment of various human diseases in the United States. The company's lead product candidate, tovecimig, is a bispecific antibody that targets delta-like ligand 4 (DLL4) and vascular endothelial growth factor A (VEGF-A), which are critical to angiogenesis and tumor vascularization. It also develops CTX-471, an IgG4 monoclonal antibody that is an agonist of CD137, a key co-stimulatory receptor on immune cells; CTX-8371, a bispecific inhibitor that targets programmed cell death protein-1 (PD-1) and ligand PD-L1 checkpoint inhibitor antibodies; and CTX-10726, a bispecific antibody that targets PD-1 and VEFG-A. The company was founded in 2014 and is headquartered in Boston, Massachusetts.
Long Name Compass Therapeutics, Inc.
Market us_market
Market Cap 1,080,527,488
Market State CLOSED
Max Age 86,400
Message Board Id finmb_266166780
Most Recent Quarter 1,767,139,200
Net Income To Common -66,489,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 1,079,627,050
Number Of Analyst Opinions 14
Open 6.6
Operating Cashflow -49,143,000
Operating Margins 0.0
Overall Risk 8
Payout Ratio 0.0
Phone 617 500 8099
Post Market Change 0.00019979477
Post Market Change Percent 0.003329913
Post Market Price 6.0002
Post Market Time 1,776,469,673
Previous Close 6.53
Price Eps Current Year -14.606714
Price Hint 2
Price To Book 5.434783
Profit Margins 0.0
Quick Ratio 14.956
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.1875
Region US
Regular Market Change -0.53
Regular Market Change Percent -8.11639
Regular Market Day High 6.67
Regular Market Day Low 5.87
Regular Market Day Range 5.87 - 6.67
Regular Market Open 6.6
Regular Market Previous Close 6.53
Regular Market Price 6.0
Regular Market Time 1,776,456,001
Regular Market Volume 3,731,736
Return On Assets -0.25292
Return On Equity -0.41294
Sand P52 Week Change 0.38150132
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 8
Shares Outstanding 180,087,915
Shares Percent Shares Out 0.1451
Shares Short 26,127,480
Shares Short Previous Month Date 1,772,150,400
Shares Short Prior Month 23,008,490
Short Name Compass Therapeutics, Inc.
Short Percent Of Float 0.22760001
Short Ratio 12.39
Source Interval 15
State MA
Symbol CMPX
Target High Price 30.0
Target Low Price 8.0
Target Mean Price 13.64286
Target Median Price 12.0
Total Cash 208,906,000
Total Cash Per Share 1.16
Total Debt 9,829,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -0.42
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 4.5695
Two Hundred Day Average Change 1.4305
Two Hundred Day Average Change Percent 0.31305397
Type Disp Equity
Volume 3,731,736
Website https://www.compasstherapeutics.com
Zip 2,135