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Cellectis S.A. (CLLS)

Healthcare | Biotechnology | Paris, France | NasdaqGM
3.40 USD -0.11 (-3.139%) ⇩ (Aug. 28, 2026, 4 p.m. EDT)
After hours: 3.41

Short-term:★★★☆☆Long-term:★⯪☆☆☆Dividends:☆☆☆☆☆
Hot Take | Aug. 22, 2026, 4:01 a.m. EDT

The investment case here is severely compromised by a deteriorating business trajectory. Revenue has contracted by nearly 62% year-over-year, and the company is burning cash with negative operating margins and a return on equity of nearly -95%. Despite a recent price bounce, the multi-year history shows a catastrophic decline of over 89%, indicating the market has already priced in a structural failure of the current business model. The lack of any dividend payout eliminates income as a buffer, leaving investors entirely exposed to capital loss. While the analyst consensus remains 'Buy' with a target price significantly higher than the current level, this appears to be a speculative bet on a turnaround that the fundamentals currently do not support. The options market confirms this skepticism, with traders placing substantial bets on further downside. This is a high-risk situation where the gap between the optimistic analyst targets and the grim reality of shrinking revenues and losses is too wide to ignore.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoARIMA ✓0.175986
AutoETS0.179521
MSTL0.182502
AutoTheta0.202656

Forecast horizon: 45 days | Selected: AutoARIMA

Forecast Reliability
Score 37%
H-stat 3.09
Ljung-Box p 0.000
Jarque-Bera p 0.574
Excess Kurtosis -0.30
Attribute Value
Sector Healthcare
Debt to Equity Ratio 195.656
Revenue per Share 0.635
Market Cap 342,384,128
Forward P/E -5.48
Beta 2.75
Profit Margins -102.34%
Website https://www.cellectis.com

As of Aug. 22, 2026, 4:01 a.m. EDT: Speculators are positioning for a significant downside move, evidenced by heavy put open interest at the $2.50 strike across multiple expirations compared to minimal call activity. While some out-of-the-money calls exist at higher strikes ($5.00-$7.50), the volume and open interest concentration in the puts suggests a bearish bias or a hedging strategy against further declines rather than a bullish momentum play.


Info Dump

Attribute Value
52 Week Change 0.37258685
Address1 8, rue de la Croix Jarry
All Time High 50.0
All Time Low 0.963
Ask 2.99
Ask Size 1
Average Daily Volume10 Day 18,390
Average Daily Volume3 Month 28,304
Average Volume 28,304
Average Volume10Days 18,390
Beta 2.752
Bid 2.8
Bid Size 1
Book Value 0.565
City Paris
Compensation As Of Epoch Date 1,767,139,200
Country France
Crypto Tradeable 0
Currency USD
Current Price 3.4
Current Ratio 1.366
Custom Price Alert Confidence HIGH
Date Short Interest 1,786,665,600
Day High 3.57
Day Low 3.4
Debt To Equity 195.656
Display Name Cellectis
Earnings Call Timestamp End 1,774,008,000
Earnings Call Timestamp Start 1,774,008,000
Earnings Timestamp 1,786,046,400
Earnings Timestamp End 1,794,600,000
Earnings Timestamp Start 1,794,600,000
Ebitda -46,677,000
Ebitda Margins -0.73135
Enterprise To Ebitda -3.446
Enterprise To Revenue 2.52
Enterprise Value 160,837,744
Eps Forward -0.62
Eps Trailing Twelve Months -0.62
Esg Populated 0
Exchange NGM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 2.96886
Fifty Day Average Change 0.43114018
Fifty Day Average Change Percent 0.14522079
Fifty Two Week Change Percent 37.258686
Fifty Two Week High 5.48
Fifty Two Week High Change -2.08
Fifty Two Week High Change Percent -0.37956202
Fifty Two Week Low 2.35
Fifty Two Week Low Change 1.0500002
Fifty Two Week Low Change Percent 0.4468086
Fifty Two Week Range 2.35 - 5.48
Financial Currency USD
First Trade Date Milliseconds 1,427,203,800,000
Float Shares 46,787,081
Forward Eps -0.62
Forward P E -5.483871
Free Cashflow 107,701,376
Full Exchange Name NasdaqGM
Full Time Employees 224
Fullday Change -0.1102
Fullday Change Percent -3.13942
Fullday Price 3.41
Gmt Off Set Milliseconds -14,400,000
Gross Margins 1.0
Gross Profits 63,823,000
Has Pre Post Market Data 1
Held Percent Insiders 0.0
Held Percent Institutions 0.15359001
Implied Shares Outstanding 100,701,207
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Cellectis S.A., a clinical stage biotechnological company, develops products based on gene-editing with a portfolio of allogeneic chimeric antigen receptor T-cells product candidates in the field of immuno-oncology and gene therapy product candidates in other therapeutic indications. The company is developing BALLI-01, to evaluate the safety, expansion, persistence, and clinical activities of lasme-cel in patients with r/r ALL; NatHaLi-01, designed to evaluate the safety, expansion, persistence, and clinical activity of eti-cel in patients with relapsed or refractory B-Cell Non-Hodgkin's Lymphoma (B-NHL). It also develops ALPHA3, targets Large B-Cell Lymphoma (LBCL); TRAVERSE, for the treatment of patients with advanced or metastatic clear cell renal cell carcinoma (RCC). In addition, the company Melanoma, for treatment of unresectable or metastatic melanoma. Cellectis S.A. was founded in 1999 and is headquartered in Paris, France.
Long Name Cellectis S.A.
Market us_market
Market Cap 342,384,128
Market State CLOSED
Max Age 86,400
Message Board Id finmb_1216695
Most Recent Quarter 1,782,777,600
Net Income To Common -65,314,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 363,819,777
Number Of Analyst Opinions 5
Open 3.48
Operating Cashflow -41,625,000
Operating Margins -3.4068701
Payout Ratio 0.0
Phone 33 1 81 69 16 00
Post Market Change 0.0
Post Market Change Percent 0.0
Post Market Price 3.41
Post Market Time 1,787,947,451
Previous Close 3.5102
Price Hint 4
Price To Book 6.0176992
Price To Sales Trailing12 Months 5.3645883
Profit Margins -1.02336
Quick Ratio 1.336
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key none
Region US
Regular Market Change -0.11019993
Regular Market Change Percent -3.1394203
Regular Market Day High 3.57
Regular Market Day Low 3.4
Regular Market Day Range 3.4 - 3.57
Regular Market Open 3.48
Regular Market Previous Close 3.5102
Regular Market Price 3.4
Regular Market Time 1,787,947,200
Regular Market Volume 5,600
Return On Assets -0.11668
Return On Equity -0.94536
Revenue Growth -0.621
Revenue Per Share 0.635
Sand P52 Week Change 0.20504117
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 72,701,207
Shares Percent Shares Out 0.003
Shares Short 301,671
Shares Short Previous Month Date 1,784,073,600
Shares Short Prior Month 289,618
Short Name Cellectis S.A.
Short Percent Of Float 0.0055
Short Ratio 17.73
Source Interval 15
Symbol CLLS
Target High Price 10.0
Target Low Price 4.0
Target Mean Price 7.6
Target Median Price 8.0
Total Cash 166,686,000
Total Cash Per Share 2.293
Total Debt 80,350,000
Total Revenue 63,823,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -0.62
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 3.70254
Two Hundred Day Average Change -0.30253983
Two Hundred Day Average Change Percent -0.08171143
Type Disp Equity
Volume 5,600
Website https://www.cellectis.com
Zip 75,013