Codexis, Inc. (CDXS)Healthcare | Biotechnology | Redwood City, United States | NasdaqGS
1.32 USD
-0.09
(-6.383%) ⇩
(Oct. 13, 2026, 4 p.m.
EDT)
After hours: 1.36 +0.04 (2.894%) ⇧ (Oct. 13, 2026, 5:05 p.m. EDT) |
Hot Take ↕ | Oct. 10, 2026, 1:16 a.m. EDT
The investment case for Codexis is currently broken by a perfect storm of deteriorating fundamentals and overwhelming bearish sentiment. The company is hemorrhaging cash, with operating cash flow at -$10.4 million and free cash flow barely covering $2.1 million against a debt load of $72.6 million. This financial distress is reflected in the balance sheet, where debt-to-equity has exploded to 220%, and profitability metrics are deeply negative, with a return on equity of nearly -69%. The market has already punished this reality with a brutal multi-year decline; the stock is down 42% over the last nine years, trading at less than half its 2021 peak despite a recent, albeit weak, revenue recovery. The recent news of a dilutive offering reshaping the trading setup confirms that insiders and management are scrambling to raise capital, further eroding shareholder value. Options activity screams 'sell,' with traders piling into puts at every expiration while calls remain virtually dormant. The statistical forecasting model offers no help, showing a flat prediction with low confidence, which aligns with the lack of a clear catalyst for a turnaround. With no dividend to provide income and a balance sheet that looks fragile, this is a speculative trap for anyone hoping for a quick bounce without seeing concrete evidence of sustainable profitability. |
| Model | MAE |
|---|---|
| AutoARIMA ✓ | 0.054697 |
| AutoETS | 0.054703 |
| MSTL | 0.062105 |
| AutoTheta | 0.132662 |
Forecast horizon: 45 days | Selected: AutoARIMA
| Forecast Reliability | |
|---|---|
| Score | 34% |
| H-stat | 3.37 |
| Ljung-Box p | 0.000 |
| Jarque-Bera p | 0.406 |
| Excess Kurtosis | -0.84 |
| Attribute | Value |
|---|---|
| Sector | Healthcare |
| Debt to Equity Ratio | 220.241 |
| Revenue per Share | 0.857 |
| Market Cap | 144,547,616 |
| Forward P/E | -4.13 |
| Beta | 2.55 |
| Profit Margins | -39.55% |
| Website | https://www.codexis.com |
As of Oct. 10, 2026, 1:16 a.m. EDT: Speculators are aggressively positioning for downside protection, evidenced by massive put volume relative to call volume across all expirations. The ATM anchor for October puts saw significant new inflow (49 contracts vs 2 open interest), while call activity remains negligible. Open interest is heavily skewed toward out-of-the-money strikes (e.g., $5.00 calls and $2.50/$1.00 puts), indicating bets on extreme volatility or a continued decline rather than a rebound.
| Attribute | Value |
|---|---|
| 52 Week Change | -0.44047618 |
| Address1 | 200 Penobscot Drive |
| All Time High | 42.01 |
| All Time Low | 0.96 |
| Ask | 1.72 |
| Ask Size | 2 |
| Audit Risk | 5 |
| Average Daily Volume10 Day | 781,310 |
| Average Daily Volume3 Month | 1,125,926 |
| Average Volume | 1,125,926 |
| Average Volume10Days | 781,310 |
| Beta | 2.554 |
| Bid | 0.9936 |
| Bid Size | 2 |
| Board Risk | 5 |
| Book Value | 0.361 |
| City | Redwood City |
| Compensation As Of Epoch Date | 1,767,139,200 |
| Compensation Risk | 8 |
| Country | United States |
| Crypto Tradeable | 0 |
| Currency | USD |
| Current Price | 1.32 |
| Current Ratio | 3.059 |
| Custom Price Alert Confidence | HIGH |
| Date Short Interest | 1,790,726,400 |
| Day High | 1.405 |
| Day Low | 1.305 |
| Debt To Equity | 220.241 |
| Display Name | Codexis |
| Dividend Yield | 0.0 |
| Earnings Call Timestamp End | 1,786,480,200 |
| Earnings Call Timestamp Start | 1,786,480,200 |
| Earnings Timestamp | 1,786,478,400 |
| Earnings Timestamp End | 1,793,908,800 |
| Earnings Timestamp Start | 1,793,908,800 |
| Ebitda | -19,047,000 |
| Ebitda Margins | -0.24520001 |
| Enterprise To Ebitda | -8.517 |
| Enterprise To Revenue | 2.088 |
| Enterprise Value | 162,216,608 |
| Eps Current Year | -0.425 |
| Eps Forward | -0.32 |
| Eps Trailing Twelve Months | -0.33 |
| Esg Populated | 0 |
| Exchange | NMS |
| Exchange Data Delayed By | 15 |
| Exchange Timezone Name | America/New_York |
| Exchange Timezone Short Name | EDT |
| Fifty Day Average | 1.4688 |
| Fifty Day Average Change | -0.1487999 |
| Fifty Day Average Change Percent | -0.101307124 |
| Fifty Two Week Change Percent | -44.04762 |
| Fifty Two Week High | 2.98 |
| Fifty Two Week High Change | -1.66 |
| Fifty Two Week High Change Percent | -0.55704695 |
| Fifty Two Week Low | 0.96 |
| Fifty Two Week Low Change | 0.36000007 |
| Fifty Two Week Low Change Percent | 0.3750001 |
| Fifty Two Week Range | 0.96 - 2.98 |
| Financial Currency | USD |
| First Trade Date Milliseconds | 1,271,943,000,000 |
| Float Shares | 82,348,335 |
| Forward Eps | -0.32 |
| Forward P E | -4.1250005 |
| Free Cashflow | 2,129,750 |
| Full Exchange Name | NasdaqGS |
| Full Time Employees | 146 |
| Fullday Change | -0.051800013 |
| Fullday Change Percent | -3.67376 |
| Fullday Price | 1.32 |
| Gmt Off Set Milliseconds | -14,400,000 |
| Governance Epoch Date | 1,790,812,800 |
| Gross Margins | 0.24269 |
| Gross Profits | 18,852,000 |
| Has Pre Post Market Data | 1 |
| Held Percent Insiders | 0.07119 |
| Held Percent Institutions | 0.70161 |
| Implied Shares Outstanding | 109,505,765 |
| Industry | Biotechnology |
| Industry Disp | Biotechnology |
| Industry Key | biotechnology |
| Is Earnings Date Estimate | 0 |
| Language | en-US |
| Last Fiscal Year End | 1,767,139,200 |
| Long Business Summary | Codexis, Inc. provides technology solutions for therapeutics manufacturing, leveraging its proprietary CodeEvolver technology platform to discover, develop, enhance, and commercialize novel enzymes in the United States, Canada, Latin America, Europe, the Middle East, Africa, Australia, New Zealand, Southeast Asia, and China. The company develops its proprietary ECO Synthesis manufacturing platform to enable the scaled manufacture of RNAi therapeutics through an enzymatic route. It has a license agreement with Aldevron LLC and Pfizer Inc. The company was incorporated in 2002 and is headquartered in Redwood City, California. |
| Long Name | Codexis, Inc. |
| Market | us_market |
| Market Cap | 144,547,616 |
| Market State | POSTPOST |
| Max Age | 86,400 |
| Message Board Id | finmb_3160285 |
| Most Recent Quarter | 1,782,777,600 |
| Net Income To Common | -30,723,000 |
| Next Fiscal Year End | 1,798,675,200 |
| Non Diluted Market Cap | 152,760,542 |
| Number Of Analyst Opinions | 7 |
| Open | 1.39 |
| Operating Cashflow | -10,404,000 |
| Operating Margins | -0.75287 |
| Overall Risk | 7 |
| Peg Ratio | 13.53 |
| Phone | 650 421 8100 |
| Post Market Change | 0.0381999 |
| Post Market Change Percent | 2.8939319 |
| Post Market Price | 1.3582 |
| Post Market Time | 1,791,925,544 |
| Previous Close | 1.41 |
| Price Eps Current Year | -3.1058824 |
| Price Hint | 4 |
| Price To Book | 3.6565099 |
| Price To Sales Trailing12 Months | 1.8608326 |
| Profit Margins | -0.39551 |
| Quick Ratio | 2.831 |
| Quote Source Name | Nasdaq Real Time Price |
| Quote Type | EQUITY |
| Recommendation Key | none |
| Region | US |
| Regular Market Change | -0.0899999 |
| Regular Market Change Percent | -6.38297 |
| Regular Market Day High | 1.405 |
| Regular Market Day Low | 1.305 |
| Regular Market Day Range | 1.305 - 1.405 |
| Regular Market Open | 1.39 |
| Regular Market Previous Close | 1.41 |
| Regular Market Price | 1.32 |
| Regular Market Time | 1,791,921,601 |
| Regular Market Volume | 820,164 |
| Return On Assets | -0.11738 |
| Return On Equity | -0.69361 |
| Revenue Growth | -0.027 |
| Revenue Per Share | 0.857 |
| Sand P52 Week Change | 0.17502642 |
| Sector | Healthcare |
| Sector Disp | Healthcare |
| Sector Key | healthcare |
| Share Holder Rights Risk | 8 |
| Shares Outstanding | 109,505,765 |
| Shares Percent Shares Out | 0.0442 |
| Shares Short | 4,839,321 |
| Shares Short Previous Month Date | 1,788,134,400 |
| Shares Short Prior Month | 3,848,350 |
| Short Name | Codexis, Inc. |
| Short Percent Of Float | 0.044699997 |
| Short Ratio | 5.54 |
| Source Interval | 15 |
| State | CA |
| Symbol | CDXS |
| Target High Price | 11.0 |
| Target Low Price | 2.0 |
| Target Mean Price | 6.14286 |
| Target Median Price | 5.0 |
| Total Cash | 54,918,000 |
| Total Cash Per Share | 0.502 |
| Total Debt | 72,587,000 |
| Total Revenue | 77,679,000 |
| Tradeable | 0 |
| Trailing Annual Dividend Rate | 0.0 |
| Trailing Annual Dividend Yield | 0.0 |
| Trailing Eps | -0.33 |
| Trailing Peg Ratio | None |
| Triggerable | 1 |
| Two Hundred Day Average | 1.84485 |
| Two Hundred Day Average Change | -0.5248499 |
| Two Hundred Day Average Change Percent | -0.28449464 |
| Type Disp | Equity |
| Volume | 820,164 |
| Website | https://www.codexis.com |
| Zip | 94,063 |