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C4 Therapeutics, Inc. (CCCC)

Healthcare | Biotechnology | Watertown, United States | NasdaqGS
3.85 USD -0.25 (-6.098%) ⇩ (Aug. 28, 2026, 4 p.m. EDT)
After hours: 3.91 +0.06 (1.538%) ⇧ (Aug. 28, 2026, 7:59 p.m. EDT)

Short-term:★★⯪☆☆Long-term:★☆☆☆☆Dividends:☆☆☆☆☆
Hot Take | Aug. 22, 2026, 2:36 a.m. EDT

The long-term investment case is severely compromised by a brutal four-year trajectory where the stock has lost nearly 94% of its value. While the company boasts a fortress balance sheet with minimal debt and strong gross margins, the market has punished the business with a structural decline, evidenced by three consecutive years of negative annual returns. This persistent underperformance suggests the market views the current management or pipeline execution as fundamentally flawed, rendering the attractive valuation metrics a 'value trap' rather than a bargain. The short-term outlook remains murky; while the stock recently rallied off its lows, the statistical forecast offers no directional clarity, and the heavy options positioning indicates traders are waiting for a specific catalyst rather than betting on organic recovery. Without a clear turnaround in the underlying business quality, the risk of further deterioration outweighs the potential for a rebound.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoTheta ✓0.099113
AutoARIMA0.113301
AutoETS0.113558
MSTL0.122720

Forecast horizon: 45 days | Selected: AutoTheta

Forecast Reliability
Score 35%
H-stat 2.24
Ljung-Box p 0.000
Jarque-Bera p 0.285
Excess Kurtosis -0.84
Attribute Value
Sector Healthcare
Debt to Equity Ratio 22.995
Revenue per Share 0.314
Market Cap 473,646,752
Forward P/E -3.86
Beta 2.95
Profit Margins -289.44%
Website https://www.c4therapeutics.com

As of Aug. 22, 2026, 2:36 a.m. EDT: Speculators are positioning for a binary event rather than steady appreciation. There is heavy open interest in out-of-the-money calls (strikes $6.00 and $9.00) expiring in late 2026 and early 2027, suggesting a bet on a massive price surge or successful clinical milestone. Conversely, significant put volume exists at lower strikes ($2.00, $3.00) for near-term expirations, indicating a hedge against continued volatility or failure. The implied volatility skew is extreme, with deep OTM calls priced at a premium relative to ATM options, reflecting high uncertainty about the stock's ability to recover from its multi-year decline.


Info Dump

Attribute Value
52 Week Change 0.6334661
Address1 490 Arsenal Way
Address2 Suite120
All Time High 51.21
All Time Low 1.06
Ask 5.06
Ask Size 2
Average Analyst Rating 1.1 - Strong Buy
Average Daily Volume10 Day 2,453,540
Average Daily Volume3 Month 3,053,956
Average Volume 3,053,956
Average Volume10Days 2,453,540
Beta 2.946
Bid 3.89
Bid Size 1
Book Value 2.012
City Watertown
Compensation As Of Epoch Date 1,767,139,200
Country United States
Crypto Tradeable 0
Currency USD
Current Price 3.85
Current Ratio 5.449
Custom Price Alert Confidence HIGH
Date Short Interest 1,786,665,600
Day High 4.1
Day Low 3.83
Debt To Equity 22.995
Display Name C4 Therapeutics
Earnings Timestamp 1,786,451,400
Earnings Timestamp End 1,793,881,800
Earnings Timestamp Start 1,793,881,800
Ebitda -99,448,000
Ebitda Margins -2.83821
Enterprise To Ebitda -2.784
Enterprise To Revenue 7.901
Enterprise Value 276,841,760
Eps Current Year -0.885
Eps Forward -0.9975
Eps Trailing Twelve Months -0.85
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 3.9589
Fifty Day Average Change -0.10890007
Fifty Day Average Change Percent -0.027507659
Fifty Two Week Change Percent 63.34661
Fifty Two Week High 5.17
Fifty Two Week High Change -1.3200002
Fifty Two Week High Change Percent -0.25531918
Fifty Two Week Low 1.69
Fifty Two Week Low Change 2.1599998
Fifty Two Week Low Change Percent 1.2781063
Fifty Two Week Range 1.69 - 5.17
Financial Currency USD
First Trade Date Milliseconds 1,601,645,400,000
Float Shares 94,515,291
Forward Eps -0.9975
Forward P E -3.859649
Free Cashflow -43,664,000
Full Exchange Name NasdaqGS
Full Time Employees 104
Fullday Change -0.25
Fullday Change Percent -6.09756
Fullday Price 3.9092
Gmt Off Set Milliseconds -14,400,000
Gross Margins 0.86344004
Gross Profits 30,254,000
Has Pre Post Market Data 1
Held Percent Insiders 0.00835
Held Percent Institutions 1.02023
Implied Shares Outstanding 123,025,136
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Ipo Expected Date 2,020-10-02
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary C4 Therapeutics, Inc., a clinical-stage biopharmaceutical company, develops novel therapeutic candidates to degrade disease-causing proteins. Its lead product candidate is Cemsidomide, an orally bioavailable monodac targeting IKZF1 and IKZF3, or IKZF1/3 to address a need across multiple lines of therapy in multiple myeloma, which has competed its phase 1. The company is also developing oncology product candidate, CFT8919, an orally bioavailable, allosteric, mutant-selective bidac degrader of epidermal growth factor receptor, with an L858R mutation in non-small cell lung cancer; and new degraders focused on inflammation, neuroinflammation, and neurodegeneration. It has strategic collaborations F. Hoffmann-La Roche Ltd and Hoffmann-La Roche Inc., Betta Pharmaceuticals Co. Ltd., and Merck KGAA. Additionally, it has a collaboration agreement with Roche Holding AG for the development of Degrader-Antibody Conjugates for cancer treatment. The company was incorporated in 2015 and is headquartered in Watertown, Massachusetts.
Long Name C4 Therapeutics, Inc.
Market us_market
Market Cap 473,646,752
Market State CLOSED
Max Age 86,400
Message Board Id finmb_321572356
Most Recent Quarter 1,782,777,600
Net Income To Common -101,416,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 503,787,931
Number Of Analyst Opinions 6
Open 4.07
Operating Cashflow -84,870,000
Operating Margins -3.9787703
Payout Ratio 0.0
Phone 617 231 0700
Post Market Change 0.05920005
Post Market Change Percent 1.5376636
Post Market Price 3.9092
Post Market Time 1,787,961,554
Previous Close 4.1
Price Eps Current Year -4.350282
Price Hint 4
Price To Book 1.9135188
Price To Sales Trailing12 Months 13.517702
Profit Margins -2.89437
Quick Ratio 5.285
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.14286
Region US
Regular Market Change -0.25
Regular Market Change Percent -6.09756
Regular Market Day High 4.1
Regular Market Day Low 3.83
Regular Market Day Range 3.83 - 4.1
Regular Market Open 4.07
Regular Market Previous Close 4.1
Regular Market Price 3.85
Regular Market Time 1,787,947,201
Regular Market Volume 1,823,145
Return On Assets -0.19253999
Return On Equity -0.48141
Revenue Growth 0.028
Revenue Per Share 0.314
Sand P52 Week Change 0.20504117
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 123,025,136
Shares Percent Shares Out 0.2768
Shares Short 34,048,321
Shares Short Previous Month Date 1,784,073,600
Shares Short Prior Month 23,815,010
Short Name C4 Therapeutics, Inc.
Short Percent Of Float 0.2784
Short Ratio 12.57
Source Interval 15
State MA
Symbol CCCC
Target High Price 30.0
Target Low Price 7.0
Target Mean Price 13.33333
Target Median Price 11.0
Total Cash 253,663,008
Total Cash Per Share 2.062
Total Debt 56,858,000
Total Revenue 35,039,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -0.85
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 3.004425
Two Hundred Day Average Change 0.84557486
Two Hundred Day Average Change Percent 0.28144315
Type Disp Equity
Volume 1,823,145
Website https://www.c4therapeutics.com
Zip 2,472