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C4 Therapeutics, Inc. (CCCC)

Healthcare | Biotechnology | Watertown, United States | NasdaqGS
3.92 USD -0.14 (-3.448%) ⇩ (July 13, 2026, 4 p.m. EDT)
After hours: 3.92

Short-term:★★☆☆☆Long-term:★☆☆☆☆Dividends:☆☆☆☆☆
Hot Take | July 11, 2026, 6:34 a.m. EDT

The investment case for C4 Therapeutics is severely compromised by a catastrophic multi-year price trajectory. Despite a recent technical bounce and positive news regarding pipeline developments, the stock has lost over 94% of its value since 2021, with the most recent annual return being a sharp decline of nearly 56%. This is not a temporary correction; it is a structural implosion where the market has repeatedly rejected the company's value proposition. Fundamentally, the business is bleeding cash with negative operating margins and no revenue growth, while the balance sheet remains fragile relative to the burn rate. The options market confirms this pessimism, with traders piling into deep out-of-the-money puts to insure against further losses. While the biotech sector often offers binary outcomes, the combination of deteriorating fundamentals, a broken price trend, and aggressive short-term hedging suggests this is a value trap rather than a turnaround opportunity. Investors should avoid this security until there is clear, sustained evidence of commercial success or a drastic reduction in burn rate.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoETS ✓0.259477
MSTL0.260157
AutoARIMA0.264655
MSTL_1260.292372
AutoTheta0.298489

Forecast horizon: 60 days | Selected: AutoETS

Forecast Reliability
Score 26%
H-stat 27.68
Ljung-Box p 0.000
Jarque-Bera p 0.090
Excess Kurtosis -1.33
Attribute Value
Sector Healthcare
Debt to Equity Ratio 24.951
Revenue per Share 0.36
Market Cap 433,423,520
Forward P/E -3.77
Beta 2.91
Profit Margins -297.76%
Website https://www.c4therapeutics.com

As of July 11, 2026, 6:34 a.m. EDT: Speculators are aggressively positioning for downside protection, evidenced by massive put volume and open interest at strikes significantly below the current price ($1.00, $2.00, $3.00) across multiple expirations. While there is some call activity at higher strikes ($9.00) for later dates, the overwhelming sentiment is hedging against a collapse, with implied volatility spiking on deep out-of-the-money puts. The options market is pricing in a high probability of further decline rather than a rally.


Info Dump

Attribute Value
52 Week Change 0.7058823
Address1 490 Arsenal Way
Address2 Suite120
All Time High 51.21
All Time Low 1.06
Ask 4.9
Ask Size 2
Average Daily Volume10 Day 5,591,020
Average Daily Volume3 Month 3,097,868
Average Volume 3,097,868
Average Volume10Days 5,591,020
Beta 2.91
Bid 2.91
Bid Size 2
Book Value 2.252
City Watertown
Compensation As Of Epoch Date 1,767,139,200
Country United States
Crypto Tradeable 0
Currency USD
Current Price 3.92
Current Ratio 9.005
Custom Price Alert Confidence HIGH
Date Short Interest 1,782,777,600
Day High 4.05
Day Low 3.83
Debt To Equity 24.951
Display Name C4 Therapeutics
Earnings Timestamp 1,778,589,000
Earnings Timestamp End 1,786,019,400
Earnings Timestamp Start 1,786,019,400
Ebitda -101,203,000
Ebitda Margins -2.90304
Enterprise To Ebitda -2.532
Enterprise To Revenue 7.349
Enterprise Value 256,199,504
Eps Current Year -0.956
Eps Forward -1.04
Eps Trailing Twelve Months -1.06
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 3.7503
Fifty Day Average Change 0.16970015
Fifty Day Average Change Percent 0.045249753
Fifty Two Week Change Percent 70.588234
Fifty Two Week High 5.17
Fifty Two Week High Change -1.25
Fifty Two Week High Change Percent -0.24177949
Fifty Two Week Low 1.69
Fifty Two Week Low Change 2.23
Fifty Two Week Low Change Percent 1.3195266
Fifty Two Week Range 1.69 - 5.17
Financial Currency USD
First Trade Date Milliseconds 1,601,645,400,000
Float Shares 83,714,866
Forward Eps -1.04
Forward P E -3.769231
Free Cashflow -53,370,752
Full Exchange Name NasdaqGS
Full Time Employees 104
Gmt Off Set Milliseconds -14,400,000
Gross Margins 0.78339994
Gross Profits 27,310,000
Has Pre Post Market Data 1
Held Percent Insiders 0.00921
Held Percent Institutions 0.85310996
Implied Shares Outstanding 110,567,222
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Ipo Expected Date 2,020-10-02
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary C4 Therapeutics, Inc., a clinical-stage biopharmaceutical company, develops novel therapeutic candidates to degrade disease-causing proteins. Its lead product candidate is Cemsidomide, an orally bioavailable monodac targeting IKZF1 and IKZF3, or IKZF1/3 to address a need across multiple lines of therapy in multiple myeloma, which has competed its phase 1. The company is also developing oncology product candidate, CFT8919, an orally bioavailable, allosteric, mutant-selective bidac degrader of epidermal growth factor receptor, with an L858R mutation in non-small cell lung cancer; and new degraders focused on inflammation, neuroinflammation, and neurodegeneration. It has strategic collaborations F. Hoffmann-La Roche Ltd and Hoffmann-La Roche Inc., Betta Pharmaceuticals Co. Ltd., and Merck KGAA. Additionally, it has a collaboration agreement with Roche Holding AG for the development of Degrader-Antibody Conjugates for cancer treatment. The company was incorporated in 2015 and is headquartered in Watertown, Massachusetts.
Long Name C4 Therapeutics, Inc.
Market us_market
Market Cap 433,423,520
Market State PREPRE
Max Age 86,400
Message Board Id finmb_321572356
Most Recent Quarter 1,774,915,200
Net Income To Common -103,801,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 448,902,921
Number Of Analyst Opinions 6
Open 4.04
Operating Cashflow -95,353,000
Operating Margins -4.51642
Payout Ratio 0.0
Phone 617 231 0700
Post Market Change 0.0
Post Market Change Percent 0.0
Post Market Price 3.92
Post Market Time 1,783,986,710
Previous Close 4.06
Price Eps Current Year -4.1004186
Price Hint 4
Price To Book 1.740675
Price To Sales Trailing12 Months 12.432905
Profit Margins -2.9775698
Quick Ratio 8.755
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key none
Region US
Regular Market Change -0.14
Regular Market Change Percent -3.44827
Regular Market Day High 4.05
Regular Market Day Low 3.83
Regular Market Day Range 3.83 - 4.05
Regular Market Open 4.04
Regular Market Previous Close 4.06
Regular Market Price 3.92
Regular Market Time 1,783,972,801
Regular Market Volume 2,990,561
Return On Assets -0.19878
Return On Equity -0.48348
Revenue Growth -0.15
Revenue Per Share 0.36
Sand P52 Week Change 0.20847368
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 110,567,222
Shares Percent Shares Out 0.22610001
Shares Short 24,997,175
Shares Short Previous Month Date 1,780,012,800
Shares Short Prior Month 21,650,001
Short Name C4 Therapeutics, Inc.
Short Percent Of Float 0.22760001
Short Ratio 7.08
Source Interval 15
State MA
Symbol CCCC
Target High Price 30.0
Target Low Price 7.0
Target Mean Price 13.33333
Target Median Price 11.0
Total Cash 235,671,008
Total Cash Per Share 2.131
Total Debt 58,447,000
Total Revenue 34,861,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -1.06
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 2.7542
Two Hundred Day Average Change 1.1658001
Two Hundred Day Average Change Percent 0.42328084
Type Disp Equity
Volume 2,990,561
Website https://www.c4therapeutics.com
Zip 2,472