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Crescent Biopharma, Inc. (CBIO)

Healthcare | Biotechnology | Waltham, United States | NasdaqCM
12.91 USD -1.55 (-10.719%) ⇩ (Oct. 13, 2026, 4 p.m. EDT)

Short-term:★★☆☆☆Long-term:★☆☆☆☆Dividends:☆☆☆☆☆
Hot Take ↕ | Oct. 10, 2026, 5:21 a.m. EDT

The long-term investment case is severely compromised by a brutal multi-year decline. Over the last nine years, the stock has lost over 98% of its value, with the most recent annual performance showing another significant drop. While the company boasts a fortress balance sheet with negligible debt and massive cash reserves, the market has clearly priced in a lack of sustainable growth or profitability, evidenced by negative earnings and operating margins. The recent surge in price appears to be a speculative anomaly rather than a fundamental turnaround, given the persistent negative earnings trajectory and the overwhelming bearish sentiment in the options chain. Investors should view this as a high-risk speculative vehicle rather than a solid long-term holding, as the structural deterioration in the stock's price history suggests the market sees no immediate path to recovery.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoETS ✓0.077090
AutoARIMA0.077239
MSTL0.077781
AutoTheta0.113615

Forecast horizon: 45 days | Selected: AutoETS

Forecast Reliability
Score 37%
H-stat 3.22
Ljung-Box p 0.000
Jarque-Bera p 0.791
Excess Kurtosis -0.45
Attribute Value
Sector Healthcare
Last Dividend Date 2023-01-12
Debt to Equity Ratio 0.88
Revenue per Share 0.434
Market Cap 479,565,600
Forward P/E -4.91
Website https://crescentbiopharma.com

As of Oct. 10, 2026, 5:21 a.m. EDT: Speculators are overwhelmingly positioning for downside protection rather than upside participation. Put open interest significantly exceeds call open interest across nearly all expirations, with heavy concentration in strikes below the current price (e.g., $10 and $12.50). Call activity is sparse and skewed toward deep out-of-the-money strikes, suggesting a 'lottery ticket' mentality rather than a conviction bet on a near-term rally. Implied volatility remains elevated relative to the low option prices, indicating fear of further declines.


Dividend Data

Dividend History
Date Dividend Yield %
2023-01-13 24.0 7.94702
2022-09-21 143.0 223.43750
Additional Data
dividendYield 0.0
trailingAnnualDividendRate 0.0
trailingAnnualDividendYield 0.0
lastDividendValue 24.0
lastDividendDate 2023-01-13

Info Dump

Attribute Value
52 Week Change 0.28077948
Address1 300 Fifth Avenue
All Time High 2,605.0
All Time Low 8.72
Ask 16.64
Ask Size 2
Audit Risk 8
Average Analyst Rating 1.1 - Strong Buy
Average Daily Volume10 Day 408,920
Average Daily Volume3 Month 405,509
Average Volume 405,509
Average Volume10Days 408,920
Bid 10.23
Bid Size 2
Board Risk 6
Book Value 4.766
City Waltham
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 8
Country United States
Crypto Tradeable 0
Currency USD
Current Price 12.91
Current Ratio 9.657
Custom Price Alert Confidence HIGH
Date Short Interest 1,790,726,400
Day High 14.67
Day Low 12.85
Debt To Equity 0.88
Display Name Crescent Biopharma
Dividend Yield 0.0
Ebitda -170,028,000
Ebitda Margins 0.0
Enterprise To Ebitda -2.273
Enterprise To Revenue 32.518
Enterprise Value 386,405,696
Eps Current Year -2.35333
Eps Forward -2.63
Eps Trailing Twelve Months -7.63
Esg Populated 0
Exchange NCM
Exchange Data Delayed By 15
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 16.6386
Fifty Day Average Change -3.7285995
Fifty Day Average Change Percent -0.22409335
Fifty Two Week Change Percent 28.077948
Fifty Two Week High 27.41
Fifty Two Week High Change -14.5
Fifty Two Week High Change Percent -0.52900404
Fifty Two Week Low 8.72
Fifty Two Week Low Change 4.1899996
Fifty Two Week Low Change Percent 0.4805045
Fifty Two Week Range 8.72 - 27.41
Financial Currency USD
First Trade Date Milliseconds 1,389,364,200,000
Float Shares 27,030,582
Forward Eps -2.63
Forward P E -4.908745
Full Exchange Name NasdaqCM
Full Time Employees 69
Fullday Change -1.5500002
Fullday Change Percent -10.719227
Fullday Price 12.91
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,790,812,800
Gross Margins 1.0
Gross Profits 11,883,000
Has Pre Post Market Data 1
Held Percent Insiders 0.0026800002
Held Percent Institutions 0.82941
Implied Shares Outstanding 37,146,830
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Language en-US
Last Dividend Date 1,673,568,000
Last Dividend Value 24.0
Last Fiscal Year End 1,767,139,200
Last Split Date 1,750,032,000
Last Split Factor 1:100
Long Business Summary Crescent Biopharma, Inc., a biotechnology company, researches and develops cancer therapy candidates in the United States. Its pipeline includes CR-001, which is in Phase 3 clinical trial, a proprietary anti-PD-1/anti-VEGF bispecific antibody to treat solid tumors; and CR-002, and CR-003. The company has a strategic partnership with Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. for the development and commercialization of oncology therapeutics. The company was formerly known as GlycoMimetics, Inc. The company was founded in 2024 and is headquartered in Waltham, Massachusetts.
Long Name Crescent Biopharma, Inc.
Market us_market
Market Cap 479,565,600
Market State PRE
Max Age 86,400
Message Board Id finmb_1902132924
Most Recent Quarter 1,782,777,600
Net Income To Common -165,124,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 527,113,517
Number Of Analyst Opinions 6
Open 14.46
Operating Cashflow -72,679,000
Operating Margins -14.32635
Overall Risk 10
Phone 617 460 5595
Previous Close 14.46
Price Eps Current Year -5.4858437
Price Hint 2
Price To Book 2.7087705
Price To Sales Trailing12 Months 40.357285
Profit Margins 0.0
Quick Ratio 9.257
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.125
Region US
Regular Market Change -1.55
Regular Market Change Percent -10.7192
Regular Market Day High 14.67
Regular Market Day Low 12.85
Regular Market Day Range 12.85 - 14.67
Regular Market Open 14.46
Regular Market Previous Close 14.46
Regular Market Price 12.91
Regular Market Time 1,791,921,601
Regular Market Volume 197,106
Revenue Per Share 0.434
Sand P52 Week Change 0.17502642
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 10
Shares Outstanding 37,143,940
Shares Percent Shares Out 0.1286
Shares Short 4,777,172
Shares Short Previous Month Date 1,788,134,400
Shares Short Prior Month 3,172,374
Short Name Crescent Biopharma, Inc.
Short Percent Of Float 0.2207
Short Ratio 8.78
Source Interval 15
State MA
Symbol CBIO
Target High Price 36.0
Target Low Price 27.0
Target Mean Price 31.5
Target Median Price 31.5
Total Cash 171,592,992
Total Cash Per Share 4.009
Total Debt 1,437,000
Total Revenue 11,883,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -7.63
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 15.7842
Two Hundred Day Average Change -2.8741999
Two Hundred Day Average Change Percent -0.18209349
Type Disp Equity
Volume 197,106
Website https://crescentbiopharma.com
Zip 2,451