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Caris Life Sciences, Inc. (CAI)

Healthcare | Biotechnology | Irving, United States | NasdaqGS
21.15 USD +0.75 (3.676%) ⇧ (April 17, 2026, 4 p.m. EDT)
After hours: 21.36 +0.21 (0.993%) ⇧ (April 17, 2026, 7:33 p.m. EDT)

Short-term: ★★★☆☆ | Long-term: ★★☆☆☆ | Dividends: ☆☆☆☆☆
Hot Take | April 18, 2026, 11:35 p.m. EDT

Despite negative earnings (forever P/L) and poor short-term forecasting models (-1.2% predicted move), Caris (CAI) presents a flawed but intriguing long-term asymmetric bet. The market has punished the stock for being below its 200-day average, yet the options market is betting hard on a multi-year recovery. The fundamental picture remains weak with 74% debt-to-equity and 56x forward PE based on losses, offering no margin of safety. However, the 'hot take' at the bottom of the well is the 13x analyst consensus 'Strong Buy' rating, which is rare for a biotech in distress, suggesting a catalyst (e.g., drug approval or data readout) could be concealed within the upcoming earnings report. Buy only on speculation of that catalyst, not for quarterly results.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
MSTL ✓0.258492
AutoETS0.269685
AutoTheta0.269835
AutoARIMA0.270685

Forecast horizon: 45 days | Selected: MSTL

Forecast Reliability
Score 38%
H-stat 2.27
Ljung-Box p 0.000
Jarque-Bera p 0.006
Excess Kurtosis 1.10
Attribute Value
Sector Healthcare
Debt to Equity Ratio 74.083
Revenue per Share 4.856
Market Cap 5,976,564,736
Forward P/E 56.62
Profit Margins -8.39%
Website https://www.carislifesciences.com

As of April 18, 2026, 11:35 p.m. EDT: Options flow shows a distinct bullish bias on the long duration (>6 months). Call OI is heavily skewed out-of-the-money (OTM) with massive positioning at strikes 30.0 and 35.0 for the July and October 2026 expirations, indicating speculation of a significant 50%+ move by year-end. Conversely, put positioning is front-loaded for downside protection below the current price (15.0–20.0 strikes for May/July), suggesting investors are hedging against a potential immediate 10-20% correction, but are confident of a recovery in 6+ months. The ATM call premium is relatively cheap compared to the depth of OTM call interest.


Info Dump

Attribute Value
52 Week Change -0.24464285
Address1 750 West John Carpenter Freeway
Address2 Suite 800
All Time High 42.5
All Time Low 16.28
Ask 22.68
Ask Size 2
Average Analyst Rating 1.4 - Strong Buy
Average Daily Volume10 Day 1,818,290
Average Daily Volume3 Month 2,426,870
Average Volume 2,426,870
Average Volume10Days 1,818,290
Bid 19.6
Bid Size 2
Book Value 2.043
City Irving
Compensation As Of Epoch Date 1,735,603,200
Country United States
Crypto Tradeable 0
Currency USD
Current Price 21.15
Current Ratio 7.848
Custom Price Alert Confidence HIGH
Date Short Interest 1,774,915,200
Day High 21.46
Day Low 20.95
Debt To Equity 74.083
Display Name Caris Life Sciences
Earnings Call Timestamp End 1,772,141,400
Earnings Call Timestamp Start 1,772,141,400
Earnings Timestamp 1,772,139,600
Earnings Timestamp End 1,778,011,200
Earnings Timestamp Start 1,778,011,200
Ebitda 67,728,000
Ebitda Margins 0.083409995
Enterprise To Ebitda 82.768
Enterprise To Revenue 6.903
Enterprise Value 5,605,682,176
Eps Current Year 0.14008
Eps Forward 0.37354
Eps Trailing Twelve Months -3.22
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fax 866 479 4925
Fifty Day Average 19.4216
Fifty Day Average Change 1.7283993
Fifty Day Average Change Percent 0.08899366
Fifty Two Week Change Percent -24.464285
Fifty Two Week High 42.5
Fifty Two Week High Change -21.35
Fifty Two Week High Change Percent -0.50235295
Fifty Two Week Low 16.28
Fifty Two Week Low Change 4.869999
Fifty Two Week Low Change Percent 0.29913998
Fifty Two Week Range 16.28 - 42.5
Financial Currency USD
First Trade Date Milliseconds 1,750,253,400,000
Float Shares 97,083,157
Forward Eps 0.37354
Forward P E 56.620438
Free Cashflow 53,502,500
Full Exchange Name NasdaqGS
Full Time Employees 1,846
Gmt Off Set Milliseconds -14,400,000
Gross Margins 0.66628
Gross Profits 541,038,016
Has Pre Post Market Data 1
Held Percent Insiders 0.48583
Held Percent Institutions 0.51936
Implied Shares Outstanding 282,579,919
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Ipo Expected Date 2,025-06-18
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Caris Life Sciences, Inc., an artificial intelligence TechBio company, provides molecular profiling services in the United States and internationally. It develops and commercializes solutions to transform healthcare using molecular information, and artificial intelligence/machine learning algorithms. The company's molecular intelligence product portfolio includes MI Profile Platform, a whole exome sequencing (WES)/ whole transcriptome sequencing (WTS) tissue-based molecular profiling solutions; Caris Assure Platform WES/WTS blood-based molecular profiling solutions; Precision Whole Genome Platform, a whole genome sequencing (WGS) blood- and tissue-based profiling solutions; and Caris Detect, a WGS-based multi-cancer early detection solution; Caris WGS MRD a WGS and digital droplet polymerase reaction-based minimal residual disease solution; and Caris ChromoSeq, a WGS and WTS based assay for therapy selection in hematological cancers. It also offers pharma research and development services comprising laboratory delivery, strategic data, and research services to biopharmaceutical customers. The company provides its precision oncology solutions to customers, such as hospitals, institutions and patients. The company was founded in 2008 and is headquartered in Irving, Texas.
Long Name Caris Life Sciences, Inc.
Market us_market
Market Cap 5,976,564,736
Market State CLOSED
Max Age 86,400
Message Board Id finmb_285971879
Most Recent Quarter 1,767,139,200
Net Income To Common -537,956,992
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 5,976,565,286
Number Of Analyst Opinions 13
Open 21.0
Operating Cashflow 83,155,000
Operating Margins 0.30186
Payout Ratio 0.0
Phone 866 771 8946
Post Market Change 0.21000099
Post Market Change Percent 0.99291253
Post Market Price 21.36
Post Market Time 1,776,468,827
Previous Close 20.4
Price Eps Current Year 150.98514
Price Hint 2
Price To Book 10.352423
Price To Sales Trailing12 Months 7.360002
Profit Margins -0.083850004
Quick Ratio 7.163
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.38462
Region US
Regular Market Change 0.75
Regular Market Change Percent 3.67647
Regular Market Day High 21.46
Regular Market Day Low 20.95
Regular Market Day Range 20.95 - 21.46
Regular Market Open 21.0
Regular Market Previous Close 20.4
Regular Market Price 21.15
Regular Market Time 1,776,456,001
Regular Market Volume 1,121,875
Return On Assets 0.03838
Return On Equity -0.45374
Revenue Growth 1.254
Revenue Per Share 4.856
Sand P52 Week Change 0.38150132
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 282,579,919
Shares Percent Shares Out 0.0364
Shares Short 10,294,979
Shares Short Previous Month Date 1,772,150,400
Shares Short Prior Month 6,509,779
Short Name Caris Life Sciences, Inc.
Short Percent Of Float 0.0705
Short Ratio 3.78
Source Interval 15
State TX
Symbol CAI
Target High Price 38.0
Target Low Price 21.0
Target Mean Price 29.69231
Target Median Price 30.0
Total Cash 798,569,024
Total Cash Per Share 2.826
Total Debt 427,686,016
Total Revenue 812,033,024
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -3.22
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 26.9243
Two Hundred Day Average Change -5.7742996
Two Hundred Day Average Change Percent -0.21446425
Type Disp Equity
Volume 1,121,875
Website https://www.carislifesciences.com
Zip 75,039